Basic Information

Gene Symbol
-
Assembly
GCA_949320045.1
Location
OX439453.1:2156955-2164934[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 5.7 3.4e+02 2.4 0.1 3 23 109 129 107 129 0.94
2 18 0.00056 0.034 15.0 0.5 2 23 133 155 132 155 0.90
3 18 0.018 1.1 10.2 0.5 3 23 407 428 405 428 0.95
4 18 0.057 3.4 8.7 0.2 1 20 436 455 436 457 0.95
5 18 0.044 2.6 9.0 0.6 2 23 467 488 466 488 0.94
6 18 1.3 77 4.4 1.6 1 23 504 527 504 532 0.91
7 18 0.06 3.6 8.6 4.3 1 23 536 558 536 559 0.95
8 18 0.19 11 7.0 2.5 1 19 636 654 636 659 0.82
9 18 0.099 5.9 7.9 0.6 1 23 664 687 664 687 0.94
10 18 9e-05 0.0054 17.5 2.7 1 23 693 715 693 715 0.97
11 18 1.7e-06 0.0001 22.9 1.5 1 23 722 744 722 744 0.98
12 18 4.2e-05 0.0025 18.5 1.4 1 23 749 771 749 771 0.96
13 18 0.015 0.88 10.5 1.9 1 23 777 799 777 799 0.95
14 18 1.9e-06 0.00011 22.7 1.6 1 23 805 827 805 827 0.98
15 18 2.1e-05 0.0013 19.4 2.2 2 23 834 857 834 857 0.96
16 18 0.0019 0.11 13.3 0.6 2 23 867 889 866 889 0.96
17 18 0.0079 0.47 11.4 0.5 1 23 894 916 894 916 0.97
18 18 0.00052 0.031 15.1 3.4 1 23 922 945 922 945 0.98

Sequence Information

Coding Sequence
ATGTCGTCAGACGACTCCGACGATGAGCCCTTGGCGGCGATTGCTATGAGAAATAAAACTGACTACGAAATAGAAATTTTGCCTGTTAGTGAGAGCAGGACTCGTATGAAGAAATCCATGTTGAAAAAGGACTGCGACGTGACGATAGAACTGCAGTACAAAGATGAACTGCAGTCTATAACTGTGGAGAGGCCCACAGATGTTTGGTTATACTTGAAGGACTTAAATCCCAATGGACCATACAGCTGTTTACTCTGCTCAGAATGGTTTATCAACAAGACTAAAATAGTAATTCACTATGTGGTCAATCACAAAAAGGACTTTTGTGGTATATGCAGGTATTTTGTGCCTGACAGAGAAGCATGGCAAGGTCACTTAAATTTCCACATACCATGGCAATGCTCCCAATGCCCCAAGACATTTAACAATGAACCACAATTACGTTCACACTTCAGTGAGGAGCACAACCTGGTACACTGCAGACTTTGCTACACACGTCTCGTCGACGGTGAAGATTACCACCTGCATTTGTATCAAAAACATAGTGTCACAAATGTCTCCTGCAAAAATGAGGAATGTTTCTGGGAGTTGGAACAAGAAGACTTCAAGTTCCTCTGTATCCTCTGctcaaaatcaaataactgTATTCAAACATTCTCAAATCATTACATGGCATACCACCATCTAACATTGAAGTGTTTAGCTCCTCTGATTTCAGGGAAAAACTGGAATTTCCCAGTTCAAGGTGCTGAAATCAGTACTGATTTCATTGTCAATCAACTAAAAGATTATGATAAGTATGGCTATTTGGATTTGGACAAAAAACCAGATCGGCTTATTGAGAAAGATGAAAACGTTGTTTTAACTAGAGTGATGGCTCATGAGCTTAAAACTGAGCCGAAGGAAGAAGCTGCAAGTGACTCTGAGGAGAACACTGGCACAGCTGATGAAGACGATGGTACTgcagatgatgataaaaataatgagcCTGGTACTGAAACAAATGAGTCCGACCCTAATGCTAACTGTGacgaattaaataaatcatataaAGGAGATGAAGACTTCGACACAACACAAGTTGAAATGATTTTGCTTCAGAAATGTTACCTAGACTATATCGATGACACATTGAACAGCATCAACTGTAATTTCATGCCTCAGACTTCATCAATCAATTATGGACTAGCTGATTCCGATCATCCGGTCTATATAGATTGTGATCTATGCCAAACACAGTTCACAACGCTGAACCCATTCACCCAACACATGATAAAGATGCATGGCTTTAAATATGTGCCTCTGTTTACTTGCCGAGTCTGTGCTACGACTTTTGACAGCTATACTGAGTTGGAGCAGCATGTGACTCAAGAGTTGGGAGAATTTGAGGATCTGTGGATTTGTCAGTTTTGTGAGAAGGAGTTTGATGATCGTGAGACAACTCGTAAACATTTGACAGAGCACTGGGATACTGTTGAGTATGATAACTGCTTCAGCCCACATTTGGGTTTTAAGTGTAAATATTGCCCGACCTTGTTTTGGAATGAGACGGATAGAGAAAGCCACATGGTGAGGGTACATTACCAGAAGCATAtggaaaattattataattgtgaGAGCTGTGATCAGCTTTTCAGTGACAAGGTTTGGTTCATCCACCACTACTTCACCCATCACATGACGAAGGGCGATTATCCAATCGGGTCGTACCTGCTCAAATGCGGCTTCTGTTGCACTGTGTTTCCGAACGTGGAGGAAATGAGAAGTCACTTCGATGCGAAGCACCCTGAGGCGAAGCGCATATTCTGCTCTCTCGATCCGTGCAAATACAAGCCGTTCAGTCACAAAAAGTCGTTCCATCTACATTTGAAGtcCTACCACAGTACGAAAAAGCGTCCGAAATCCTTCGCTTGCCAGTTCTGCGGCAAAGAGTTCAGCAGCCAGCGCTCGTGCAGCGCCCACAGCACGCAAGCCCACGGCCCGGGCCGCTTCACTTGCAACTTGTGCAAGGAGATGTTACGCACAGCCGACGagagGAAAATCCACTATCTCCTCCGCCACCCGGGCCGACACCCGTTCCAATGCCGCGACTGCGACAAATCATTCCAATACAAATCTTCTCTTTATCTACATCGCCAAGAACACGCGCCCAACAAACAGGATTACACATGTACCTATTGCGGAAAGGTTTTCAAGAAACGTGATTCGTTCAGAGAACACGTAATGATCCACGAAGGACCGAAGCACGCTTGCTCGTACTGCCCCATGGTGTTCGTACAGCGCTCCAACATGTTACGTCACGAGAGGAGACATACCGGCGAGCGACCTTACGCTTGCCAGTTCTGCCCTAAAACGTTCTCCGATAAGGGCGCCTGCTCTTCGCATTCAAGAATCCATCAGAAGACGCCGGCGTTTCCATGTATGTACTGCGGCCAGACCTTCGTCCAGAAGTCTAAGCTGACCTACCATATCAGAAAACATACTGGGGAGAATCTAGAGACTTGTCCGCACGCGAACTGCGGCAAGGTGTTCACGAGTCCTTGTTCTCTGCGCGAGCACATGAAGATACACGAGAGGAAGCAAATTATGAACCCCGTCAAGTGCCCGCTTTGCTCAAAGTCGTATCAAGACGAGAAGTATATGATGCGCCATTTGCGAGCGACGCATACAAACGCGGCATTCATCTGTCCGCTCTGCAAGAAGAAACTACACAGCGCCGCTTCGCTGAGGGACCATGTCGTGACACACAGCGATTCGAAGGCTTACAagTGTAATCAATGTTCCAAATCCTATAACGTGAAACGTACTATGGTAAGACACCTCCGACGTCGCCACGGCATCAAAGCATCCGGCAGCCTCACAGAATACTTCAGGAAACTGGACCCTAGAGAATTGAACTTAAACCTCGACGACGAAACAATGATCAGCATATTCGGACCCCCCAAACGAAAACACAATACAGTCAACTTCACAAACCTTAAGCGGCTTAAGCTAGACCGACCAAATGGTCCCAGTGATAATGAAAGTGAGGGTGAGAATCCACCACAGATCGAAAGCGTCCAAGTTAAGATAGAATGCGAGGAAGCTGAAGAGTCTCTTGAGAATAATGAATACCAAAATGAGTTGCAGCCAACTGATTTTGTGAGTGTTAAGATTGAGTGTGCGGACAGCATTGAGGAGGAAGAGATGGAAAATAGTGAAGAGGACTGA
Protein Sequence
MSSDDSDDEPLAAIAMRNKTDYEIEILPVSESRTRMKKSMLKKDCDVTIELQYKDELQSITVERPTDVWLYLKDLNPNGPYSCLLCSEWFINKTKIVIHYVVNHKKDFCGICRYFVPDREAWQGHLNFHIPWQCSQCPKTFNNEPQLRSHFSEEHNLVHCRLCYTRLVDGEDYHLHLYQKHSVTNVSCKNEECFWELEQEDFKFLCILCSKSNNCIQTFSNHYMAYHHLTLKCLAPLISGKNWNFPVQGAEISTDFIVNQLKDYDKYGYLDLDKKPDRLIEKDENVVLTRVMAHELKTEPKEEAASDSEENTGTADEDDGTADDDKNNEPGTETNESDPNANCDELNKSYKGDEDFDTTQVEMILLQKCYLDYIDDTLNSINCNFMPQTSSINYGLADSDHPVYIDCDLCQTQFTTLNPFTQHMIKMHGFKYVPLFTCRVCATTFDSYTELEQHVTQELGEFEDLWICQFCEKEFDDRETTRKHLTEHWDTVEYDNCFSPHLGFKCKYCPTLFWNETDRESHMVRVHYQKHMENYYNCESCDQLFSDKVWFIHHYFTHHMTKGDYPIGSYLLKCGFCCTVFPNVEEMRSHFDAKHPEAKRIFCSLDPCKYKPFSHKKSFHLHLKSYHSTKKRPKSFACQFCGKEFSSQRSCSAHSTQAHGPGRFTCNLCKEMLRTADERKIHYLLRHPGRHPFQCRDCDKSFQYKSSLYLHRQEHAPNKQDYTCTYCGKVFKKRDSFREHVMIHEGPKHACSYCPMVFVQRSNMLRHERRHTGERPYACQFCPKTFSDKGACSSHSRIHQKTPAFPCMYCGQTFVQKSKLTYHIRKHTGENLETCPHANCGKVFTSPCSLREHMKIHERKQIMNPVKCPLCSKSYQDEKYMMRHLRATHTNAAFICPLCKKKLHSAASLRDHVVTHSDSKAYKCNQCSKSYNVKRTMVRHLRRRHGIKASGSLTEYFRKLDPRELNLNLDDETMISIFGPPKRKHNTVNFTNLKRLKLDRPNGPSDNESEGENPPQIESVQVKIECEEAEESLENNEYQNELQPTDFVSVKIECADSIEEEEMENSEED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00119849;
90% Identity
-
80% Identity
-