Basic Information

Gene Symbol
-
Assembly
GCA_036419045.1
Location
CM071636.1:5325159-5328229[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.19 32 6.7 0.9 1 23 51 74 51 74 0.95
2 19 0.96 1.6e+02 4.5 0.0 2 23 104 127 103 127 0.90
3 19 0.33 54 5.9 0.4 3 23 151 172 150 172 0.95
4 19 5.3e-05 0.0087 17.9 0.3 1 23 177 200 177 200 0.97
5 19 0.0023 0.37 12.8 2.1 1 23 203 226 203 226 0.94
6 19 0.00047 0.077 14.9 1.2 3 23 234 255 233 255 0.94
7 19 0.00099 0.16 13.9 0.6 2 23 263 285 262 285 0.96
8 19 0.0068 1.1 11.3 0.6 1 23 290 312 290 312 0.98
9 19 2e-06 0.00032 22.4 0.6 1 23 318 340 318 340 0.99
10 19 0.0069 1.1 11.3 0.4 2 23 347 369 346 369 0.95
11 19 0.0049 0.81 11.7 1.6 1 23 438 460 438 460 0.99
12 19 0.2 33 6.6 0.0 3 23 487 508 485 508 0.90
13 19 0.026 4.2 9.5 1.8 2 23 531 552 530 553 0.94
14 19 0.00087 0.14 14.1 1.3 3 23 564 585 563 585 0.98
15 19 9.5e-05 0.016 17.1 0.6 3 23 592 613 591 613 0.97
16 19 0.064 10 8.2 4.1 1 23 619 642 619 642 0.98
17 19 9.3e-05 0.015 17.1 1.5 2 23 648 670 647 670 0.95
18 19 0.017 2.8 10.0 3.8 1 23 676 698 676 698 0.95
19 19 0.0053 0.86 11.6 1.0 1 23 704 727 704 727 0.91

Sequence Information

Coding Sequence
ATGATTGAGGacataaataaatctttctttCCAGGACAGTTACAAAGAGAAGAACCAAAAACACGTCAACGTCTGAACGTCCTGAGAAGGAATATTCTACTTCTCATCCACTACAGCAACATGAAGCCATTTAGATGGCACACCAAAGGATTCAGCTGTTTCTATTGTTCCATGCCGGTCAAAGATTGCGCTGCCCTCGATGCCCATTACAACTTAAAACACAAAAAGGAAATGGATGATTTAGACATCTTTATACAAAACAATGTTCTTTCGAAAGATTTTCCACTTAAAATGGATGTTTCGAATATATCCTGCAAATATTGTCCCAATATTGAATTCGTACGTACTGAAGATTTAATCGATCATGTAATTTTAGTACACAATGAAGACTATGATCAAACAGCAGGGATAAGCTTCTTACCATTTCGTCTAAGCAACGATATCATGGATTGTGTGCTATGTGACGAGCAATTTGATAATTTCACTACGATTATGAGCCACATGTATAGGCAACATGTCACACACTGCTACATGTGTCAGACGTGTGGCCTAAGCTTTGTAAATATCATCAAATTGAACCGGCATATTAAAAGTGTCCATGTTGGATATAAGTGTACCGTGTGCAAGAAATTGTTCACCAGTTATAATAAGTTGAGCGCGCACAAATCTAACATACATGGTAAAGTTGTAACACGGTGTTGCGAACTATGTAGTGCCTCGTTCAAGTCTGCCTATCAATTGAAAGTGCACATGGGAAAGGAGCACAATGTggagaaatataaaatacagtGCGAGTACTGTCCCAAAATCTGCACCACGAAAGGTGCTATGTTAACACATGTGCAGTCTTTGCATTCAGACGAGAAATACGAATGTGATCTTTGTGACTATAAAGCATCCACTCAGTGGTTGGTAAAGCTGCATAAAAGGAAGCATTTTGGCCAGAAAGATTACACGTGTAGTGTGTGTGAAAGAAAGTTTGGAAGGTCAAGTAATGTAAGGGCACATATGAAGGTGCACACTGGCCAGATAGGCAAGGTGTGCAGATGGTGTAGGTTTGGTTTTATCAGTAGTGAGACACTCGAGAAACATACTCGAGAAGCACATTTAGAACGAGAACAGCAAGGTGGCCATAATACACCGCAAACGGAGACGGAGCCTACTGTAGATGACTCTTTGGATTTATTCGATGCTCCAGTACCGATCGTACCAGGTCTGTCTGCCAAGCAAAAGCGTATCATAAAGAGAAAAAACGTATTAAATGTGCTTTTGAAATCAACAGTAATGCCATTCCGCTGGCTGAAGAGCTCCTACAGGTGTTTTTACTGCTACGAAATTTTCCAAGAAAATTTGGACTTGAAAAATCACCAGCAAATGCATTTAGACGACGCAATTAAAAAGCAAACCATGGGCAATTATTGGGACCCGATTGTTTATGTAGATATCTCAAACTTAGCTTGTAAGGAATGCGATGGAAAATTTGAAGATTTGTACGTATTAATTGACCACTTAATTGATGAACACGACGTGGAGTACAATAAAGACGTGGGCGTATGCATGGCAGCCTTCAAACTTGGTCCTGTAAGCGTTACCTGCCTGGTTTGCGGTAAGATCTATTATTCCTTTGGGCCTCTGTTGCACCACACGAACAAGCATCATAAAGAGACCACCACCACAACCGCAATCCTCTGCGATGTCTGCGGGCAACATTTCAAAGATGTGTACTACTTGAAACTACATTTCAAGACGGTTCATGAAAATACCGGAGTTCTTTGCACGGAATGCGGAGAGAAGTTTGAAACGGCGGCTAAATTGAAGACACATCAAAAGAACCAGCATTACATAGAGAAAAGATATAAATGTTTCGTCTGTTCAGAAATATTCCAGAGTCATTATAAAAGATCTAGGCATATGTCTACCGAACATAACCGAGAGGTGGTCAAGTGTCCACACTGCCCGAAGACGTTCGTCTTTAGGAGCATGATGATGACTCACGTAAGGGACACTCACCTGAAAGTTCGTAACCATATTTGTACCATATGCGGATGGAGAGCCTTCAATAGCCACCGATTGAAAAACCACATGTATAAGCACAGCGGCGAGAAGAATTTCAAATGTGATGCTTGCGGCAAAGCCTTCTcaacaaagaaaataatgaaGGCCCATTTCTCTAGAATGCACAAGGCTCCTCCCGTTCTTGTTCCGACGATGCCCTATGAGATGCCTCATAATGTATACCCAGGGCATTGA
Protein Sequence
MIEDINKSFFPGQLQREEPKTRQRLNVLRRNILLLIHYSNMKPFRWHTKGFSCFYCSMPVKDCAALDAHYNLKHKKEMDDLDIFIQNNVLSKDFPLKMDVSNISCKYCPNIEFVRTEDLIDHVILVHNEDYDQTAGISFLPFRLSNDIMDCVLCDEQFDNFTTIMSHMYRQHVTHCYMCQTCGLSFVNIIKLNRHIKSVHVGYKCTVCKKLFTSYNKLSAHKSNIHGKVVTRCCELCSASFKSAYQLKVHMGKEHNVEKYKIQCEYCPKICTTKGAMLTHVQSLHSDEKYECDLCDYKASTQWLVKLHKRKHFGQKDYTCSVCERKFGRSSNVRAHMKVHTGQIGKVCRWCRFGFISSETLEKHTREAHLEREQQGGHNTPQTETEPTVDDSLDLFDAPVPIVPGLSAKQKRIIKRKNVLNVLLKSTVMPFRWLKSSYRCFYCYEIFQENLDLKNHQQMHLDDAIKKQTMGNYWDPIVYVDISNLACKECDGKFEDLYVLIDHLIDEHDVEYNKDVGVCMAAFKLGPVSVTCLVCGKIYYSFGPLLHHTNKHHKETTTTTAILCDVCGQHFKDVYYLKLHFKTVHENTGVLCTECGEKFETAAKLKTHQKNQHYIEKRYKCFVCSEIFQSHYKRSRHMSTEHNREVVKCPHCPKTFVFRSMMMTHVRDTHLKVRNHICTICGWRAFNSHRLKNHMYKHSGEKNFKCDACGKAFSTKKIMKAHFSRMHKAPPVLVPTMPYEMPHNVYPGH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-