Basic Information

Insect: Schrankia costaestrigalis
Gene Symbol: topi
Assembly: GCA_905475405.1
Location: FR997839.1:17232019-17244296[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.039 4.9 9.1 5.1 1 23 272 294 272 294 0.97

2 11 0.00044 0.054 15.2 2.6 2 23 302 323 301 323 0.94

3 11 2 2.5e+02 3.7 0.5 1 23 327 349 327 349 0.90

4 11 0.024 3 9.8 1.5 1 23 354 377 354 377 0.97

5 11 0.0033 0.4 12.5 0.1 1 23 381 404 381 404 0.90

6 11 0.0013 0.16 13.8 0.4 2 21 421 440 421 445 0.92

7 11 0.00026 0.032 15.9 1.8 3 23 455 476 455 476 0.98

8 11 1.3e-06 0.00016 23.2 0.9 1 23 526 548 526 548 0.99

9 11 6.9e-07 8.5e-05 24.1 1.6 1 23 554 576 554 576 0.98

10 11 0.09 11 8.0 3.4 1 23 582 604 582 604 0.97

11 11 0.00031 0.038 15.7 0.1 1 23 610 633 610 633 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.039	4.9	9.1	5.1	1	23	272	294	272	294	0.97
2	11	0.00044	0.054	15.2	2.6	2	23	302	323	301	323	0.94
3	11	2	2.5e+02	3.7	0.5	1	23	327	349	327	349	0.90
4	11	0.024	3	9.8	1.5	1	23	354	377	354	377	0.97
5	11	0.0033	0.4	12.5	0.1	1	23	381	404	381	404	0.90
6	11	0.0013	0.16	13.8	0.4	2	21	421	440	421	445	0.92
7	11	0.00026	0.032	15.9	1.8	3	23	455	476	455	476	0.98
8	11	1.3e-06	0.00016	23.2	0.9	1	23	526	548	526	548	0.99
9	11	6.9e-07	8.5e-05	24.1	1.6	1	23	554	576	554	576	0.98
10	11	0.09	11	8.0	3.4	1	23	582	604	582	604	0.97
11	11	0.00031	0.038	15.7	0.1	1	23	610	633	610	633	0.97

Sequence Information

Coding Sequence: aTGGAAGACGTGAAAGTTTGTCGTGTTTGCCTCATATTAGATGTTAAAATGTATGATTTAGAAGCAAGCCCTTACGATTTATATTTTAGGTGTATAACTGGAAGTAATGTACTTTCAATAGTGAATGCACCACCGCATGCCTGCTATGAATGTATTCTATTtctaaaaaagttttacttttttaaacaaaaatgtttaagaAGTCAGGCTGTTCTATTTGGTTTATTAGACGGGAATGGAGAGaTCCCACcatcacaaataaaaaaaattgatcgCAAAAGCCTTTTGCTAACATCAAATCTCGCAATAAATGAATCGCAAGTTGAATTACATGAAGATTTTGATTCAAAGGATGATGTTAAAGAGGAAACATTAACAGAAAATGTTGGATCTAACTTTGATGTAGAAGTATCTTGTATAAAGAAAGAGGAAGTTGATGTTCTAGCACATGAGAAATGTTTGTCCAGTGATGTTGATGATCCGTATTCACCAGATAAAGAGGATAAGATTGAGGATTCTGATGATGATAGTGATTGGAGAGAGGAGACAGAAATACAAccCATAGAAACAGTGACCTGCGAATCACTCCCGATTCCTCCAAAAAGATTGCCAACTAAAAAAAGTACGGGATTAAAGAAAACCTTAAAGAAAACTATAACTAAAAGGAAAACCAGTAAAGCAGCTAGCAAGAAAACAGTAACCGATATTGAGAGTgaacttataaataatatagctaTTGTTAATGTATCTCTAGAAGATCAGTTGGAAGAAATAAACAAAAGGAAGTTGTCTACTAATTTCTTAAACTCGCCGTTTCAATGTCACCTCTGTTACAAAGGATTTATTGACACGGACACGTGGAAACATCACTCAAGTAAACATGATCCGAGTGCGGGTGATATGGAGTGTCCAATATGCAAGTGTAGGTTTAAAACGCGTCGAGCGCTTCAGAGGCATTCAATATATCATGAAAAGAAATATGTGTGTAAATCTTGTCCACATACATCTTCTAATATGGCTGTCGCGAAGAAACATCAAGGTTGGCACAAAGGAGTTACATACGAATGCAAGTTCTGCGACGATTCTTTCACCGTGTTCACATCGTATATGAGTCATGTACGTATAAAGCACCCCTCGGAGTTCATATGCGGGATCTGCGGGTACTCGTTCATTAGTAAGCTGGGACTTGCTATGCACAAGACTTTGATGCACAAAGATGTTTTGGCGAAAGGCGAAGACGACGTAGCGGAAGATGGTCCATATTGCGAAGAGTGTGACGTCAAATTCGTATCGACAGACGCGTTCAAACGTCACATGATCATGTCTACCAAACATACTAGGAATACTAAGACTATTAACGGCTGTCGTACATGCGGTGAGACATTCGAGAATTCAGAAGAGTTAAAGTTACATCATCGTAAAGCTCACGCTATTAAGAAACCCAAAAACTATGGACAGAAGATTAATTGGCCAGCCAAGTGTGAATATTGTTCAGAAGAGATGGCAAATGGACGGGAGCACTGGGCACACTTCCGTAGAGTACATCCAGACAGGAAATATCCGATACAGAAGAACTACGTCTGCGATGTCTGTGGGAAGAGTTTTAAGAACAACGCATTCCTCGTGTACCACAAGCGCACTCACACTGAAGAGCGCCTGTACCAGTGCGCGCAGTGCGACAAGTCGTTCTACACGCGCACCAACCTGCAGCTGCACCAGCGCGCGCACAGCGACACGCGCCCCTACCCCTGCGCCGTGTGCTGCAAGGCCTTCAAGTGTAAGAGTGCGCTCAAGAGACATTATATTGTACACTCAGGTCAGAAGCCATACGAATGTGAGCTATGTGGTAAGTCGTTCGCCGCAGCCAACACACGCAAGAATCACATATCTACAGTTCACTTCAAACAACCAGCGCAATATGTCAGTCGACGACGGAAAAAAAGTGAGAAGAAATCTTCTTTGCTCAATCTGtag
Protein Sequence: MEDVKVCRVCLILDVKMYDLEASPYDLYFRCITGSNVLSIVNAPPHACYECILFLKKFYFFKQKCLRSQAVLFGLLDGNGEIPPSQIKKIDRKSLLLTSNLAINESQVELHEDFDSKDDVKEETLTENVGSNFDVEVSCIKKEEVDVLAHEKCLSSDVDDPYSPDKEDKIEDSDDDSDWREETEIQPIETVTCESLPIPPKRLPTKKSTGLKKTLKKTITKRKTSKAASKKTVTDIESELINNIAIVNVSLEDQLEEINKRKLSTNFLNSPFQCHLCYKGFIDTDTWKHHSSKHDPSAGDMECPICKCRFKTRRALQRHSIYHEKKYVCKSCPHTSSNMAVAKKHQGWHKGVTYECKFCDDSFTVFTSYMSHVRIKHPSEFICGICGYSFISKLGLAMHKTLMHKDVLAKGEDDVAEDGPYCEECDVKFVSTDAFKRHMIMSTKHTRNTKTINGCRTCGETFENSEELKLHHRKAHAIKKPKNYGQKINWPAKCEYCSEEMANGREHWAHFRRVHPDRKYPIQKNYVCDVCGKSFKNNAFLVYHKRTHTEERLYQCAQCDKSFYTRTNLQLHQRAHSDTRPYPCAVCCKAFKCKSALKRHYIVHSGQKPYECELCGKSFAAANTRKNHISTVHFKQPAQYVSRRRKKSEKKSSLLNL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -