Basic Information

Gene Symbol
-
Assembly
GCA_963935595.1
Location
OZ012550.1:30601307-30608480[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 7.3e-05 0.019 17.5 0.4 1 23 511 534 511 534 0.98
2 9 0.0041 1 12.0 0.2 1 23 609 631 609 631 0.98
3 9 0.033 8.5 9.2 0.2 1 21 635 655 635 658 0.89
4 9 0.0011 0.29 13.8 1.3 1 23 665 688 665 688 0.96
5 9 0.37 94 5.9 2.7 1 23 694 717 694 717 0.80
6 9 7.8e-08 2e-05 26.9 2.5 1 23 724 746 724 746 0.99
7 9 0.00098 0.25 14.0 1.3 2 23 753 774 752 774 0.96
8 9 8.2e-07 0.00021 23.6 0.9 1 23 780 802 780 802 0.99
9 9 3.3e-06 0.00086 21.7 1.4 1 23 808 830 808 831 0.96

Sequence Information

Coding Sequence
ATGCAGCCTATCATGGGACAGTTACCATCAGAAAGAACTAATGTAACTTTTCCTTTTTATACTTGCGGCACCGATTTCGCCGGACCTTTTATGATTGCAAGTAAAAAGGGACGGGGCAGTCGCACTACTAAAGCTtatttatgcttatttatttgccTTTTAACCAAAGCAGTCCACTTAGAAGTGGTCAGCGACTTGAGTACCGAAGCCTTTATATTATGTCTGCGTCGTTTTGTATCTCGACGCGGCAAGCCCCATGCTATTCATTGTGATAATGGCAGTAACTTCATTGGCGCAAATAATGAATTAGGTAGAATTCTGCGTTCTAGCCGTAAGCCCATTGATGAATATGCTAGTAACGAGGGCATAGTCATGAAATTCATACCGGCGTATTCACCTAATTTTGGGGGGATAGAGGCTATCCTAAACTCCCGTCCTATCTCCCCCTTGTCTTCTAATCCTCAAGACCTCACTCCAATCACTCCTGGTCATTTCCTCATAGGTCGACCTCTAATGTCAGTGCCATCAGAAGTCATGGACATGGCAAGACCAAATCGATACCAGCTAATTGAGAAGATCAGACAGCAATTTTGGGAGAGATGGAGAAGGGAATATTTGTCAGAGCTCCAATCAAGATGCAAATGGCGTACCAGTCAACACAATATCAAGGTTGGCGACATGGTGCTTCTGAAGGAAGATCATGTTCCTCCACTAAAATGGCGACTAGGCCGCATCACCAAGTTGTACCCTGGACCAGACAAGATCACCAGGCTTTCACAGAAATCTGATTTAACTACCCTCATATGTTCAGAATGTATCAGAAGACTCAGGGAAGCAAGTAGTTTTAAGATTTTAGCTACAAATACTGAAAAATATCTTCTAGAATGTCATGCGAGAAGAACAGAGGGTGTAAGCACCAAAGAGATAGATGTAAACACAATTTCTTCTGAAAAATCTCATTTCAAGGCTGATCTAAAGGTGGAATCTTGGCTCATAGAGCAGAGTGATGGTGAATGCTCTGATCGAGGTGCAGACTTTGACATTTCTGAAGGTCAGGGATTTAGTGTACCTATTGGCATTGTTGTCGGCAGCAACAAAGTTGCCAATAGCGCTTTGAGCCGTCCGTACCCCCCTTTGTCGTACGGGCATTTTCTACAAATAGCTTGTTTTGCATCGAAAGGTTGGAAGCCCGATCTCTCCAGGCATTCTAGGTCCTTCAGGAAATTCACCAACTCCCAATCAGCAAGAAAACGCATAAGTGGCAAGACAATAAAATCGTTGCTGGAACAAAATCACAACCGAAAACCAAAGAAAGAAGTCAAAACGGACAAGGTGATCACTACGAAACTAGACCAACCAATGCCAATAAAAAAGAGGATACAACGAACAAAGTATTATCGGGAGAAGTTGATAAATTTGGACACAGAAAGAAATCCACATACACTCGAACGTCACTTTCACGTGACCAACATTACAGCTTTACTCGAATATTCAAATTTAACACCATTCAGAACGAAACACCAGCGCTCCTACCCATGTTTTTACTGCGGTGCGAGCTACGAAGACTTTGAGGACTTAAGGAAGCATCGAATGACAGAACACAGAAAGGAAAACGTTAGGCAACGTGTACTTGACAAATATAGAGTCGGGAAACCAGACAGTCTGGTGGTATATGCGGACGTGAAAGATTTAAAGTGCATCATTTGCGCAACAAATTTGAGTGACTTAAAGGAATTGAAGTGTCATTTGACTAGCGTTCACAACAAGCGGATGTATTTGGATTCGACGGATAGAGTGATACCGTTCAAAGTgtgtgaaaataattttatctgtCAGAACTGTGGCACTTTGTATGAGACTTTCGGTGCTATCGAGAGGCATATGAACACGCATTACAGAAATTATATATGTGAAGAATGCGATTCCGGGTTTGTAACAAAACAACGGTTGAAGATACACGGTTATTTGATGCATTCAACGCGCCCGAAGAAGTTTGCGTGCGGGAAATGCGACAAACAATTCAGTACGCAACAAAAACGTAAGACACACGTAGAGACGGTCCATGACAACGTCAAGAAGTACAAATGTAACCGGTGCCCGGAGAGATTCAACGAATACTTTAGGAGGCATAAACATATGGTTGTAGTACACGGCGTGGCCCCTATAGAATATAAGTGCAACGTTTGCGAGAAAACCTTCAATCGAAGGTACTCACTGTCAGTTCACATGCGTACACATATTCAGCAGAAAGATGTGTATTGCGAAATATGTCCGTACAGGTGTTTTACTAAGGTGGAACTTAAAAATCACATGGTAAAGCATAACGGGGAGAGGATATATGAATGTTCCATTTGTAAGAAGTCATACGCTCGAGAAAAGACGTTAAAAGAACATATGAGAATCCATACGAATGATCGTCGTTTCGTTTGTCCCGTTTGCGGTGTGGCGTTTATCCAGAATTGCAGTCTGAAGAGTCATATCAGGAGTCACCACAAAGAGCACGGTTTGActtag
Protein Sequence
MQPIMGQLPSERTNVTFPFYTCGTDFAGPFMIASKKGRGSRTTKAYLCLFICLLTKAVHLEVVSDLSTEAFILCLRRFVSRRGKPHAIHCDNGSNFIGANNELGRILRSSRKPIDEYASNEGIVMKFIPAYSPNFGGIEAILNSRPISPLSSNPQDLTPITPGHFLIGRPLMSVPSEVMDMARPNRYQLIEKIRQQFWERWRREYLSELQSRCKWRTSQHNIKVGDMVLLKEDHVPPLKWRLGRITKLYPGPDKITRLSQKSDLTTLICSECIRRLREASSFKILATNTEKYLLECHARRTEGVSTKEIDVNTISSEKSHFKADLKVESWLIEQSDGECSDRGADFDISEGQGFSVPIGIVVGSNKVANSALSRPYPPLSYGHFLQIACFASKGWKPDLSRHSRSFRKFTNSQSARKRISGKTIKSLLEQNHNRKPKKEVKTDKVITTKLDQPMPIKKRIQRTKYYREKLINLDTERNPHTLERHFHVTNITALLEYSNLTPFRTKHQRSYPCFYCGASYEDFEDLRKHRMTEHRKENVRQRVLDKYRVGKPDSLVVYADVKDLKCIICATNLSDLKELKCHLTSVHNKRMYLDSTDRVIPFKVCENNFICQNCGTLYETFGAIERHMNTHYRNYICEECDSGFVTKQRLKIHGYLMHSTRPKKFACGKCDKQFSTQQKRKTHVETVHDNVKKYKCNRCPERFNEYFRRHKHMVVVHGVAPIEYKCNVCEKTFNRRYSLSVHMRTHIQQKDVYCEICPYRCFTKVELKNHMVKHNGERIYECSICKKSYAREKTLKEHMRIHTNDRRFVCPVCGVAFIQNCSLKSHIRSHHKEHGLT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-