Basic Information

Insect: Schizotus pectinicornis
Gene Symbol: topi
Assembly: GCA_951805265.1
Location: OX638204.1:6695632-6697928[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0088 0.6 10.8 1.9 2 21 94 113 93 114 0.94

2 14 1.5e-06 0.0001 22.7 0.7 1 23 140 162 140 162 0.97

3 14 0.01 0.71 10.6 2.8 2 23 169 190 169 190 0.95

4 14 0.1 7.1 7.4 0.9 2 15 209 222 208 229 0.87

5 14 0.0015 0.1 13.3 1.2 2 23 274 295 273 295 0.97

6 14 4.5 3.1e+02 2.3 0.2 1 12 301 312 301 314 0.88

7 14 0.44 30 5.5 3.0 2 21 338 357 337 361 0.83

8 14 0.59 40 5.1 0.1 1 23 482 505 482 505 0.95

9 14 0.015 0.99 10.1 0.2 1 23 509 531 509 531 0.96

10 14 7.7e-07 5.3e-05 23.6 2.4 1 23 537 559 537 559 0.98

11 14 0.021 1.5 9.6 0.2 1 23 565 590 565 590 0.96

12 14 0.046 3.1 8.6 2.7 1 23 596 618 596 618 0.86

13 14 2e-05 0.0013 19.2 0.5 3 23 626 646 624 646 0.97

14 14 0.00039 0.026 15.1 1.7 1 23 652 675 652 675 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0088	0.6	10.8	1.9	2	21	94	113	93	114	0.94
2	14	1.5e-06	0.0001	22.7	0.7	1	23	140	162	140	162	0.97
3	14	0.01	0.71	10.6	2.8	2	23	169	190	169	190	0.95
4	14	0.1	7.1	7.4	0.9	2	15	209	222	208	229	0.87
5	14	0.0015	0.1	13.3	1.2	2	23	274	295	273	295	0.97
6	14	4.5	3.1e+02	2.3	0.2	1	12	301	312	301	314	0.88
7	14	0.44	30	5.5	3.0	2	21	338	357	337	361	0.83
8	14	0.59	40	5.1	0.1	1	23	482	505	482	505	0.95
9	14	0.015	0.99	10.1	0.2	1	23	509	531	509	531	0.96
10	14	7.7e-07	5.3e-05	23.6	2.4	1	23	537	559	537	559	0.98
11	14	0.021	1.5	9.6	0.2	1	23	565	590	565	590	0.96
12	14	0.046	3.1	8.6	2.7	1	23	596	618	596	618	0.86
13	14	2e-05	0.0013	19.2	0.5	3	23	626	646	624	646	0.97
14	14	0.00039	0.026	15.1	1.7	1	23	652	675	652	675	0.98

Sequence Information

Coding Sequence: ATGAACGTAATTGACGATAAAGCGATTTCCGTGATAAATTCGCACTATATTCGCGGAACGGACCGCGTCTTCTCCACCCGGTACGTAGCGGACCTGTTGACCCACCAATTGGTTTCGAAGGCCCCCATTTTGGGCAAGAATGTGAGTTTTAGCACCAGTTCCGGCGTAAACTTGGCCCTCTCGAATTTGGAAGTTGACTGGGGGAGCGTTAGGGTGGTGAAAATGGACCCCTCCGATCTGGCGAGGGTTAAGGCCAAAATGAACATCCCCTGCATGATTCGGTGTCAAAACTGCGAAACCAATTACCCGACCAAGTACCAATATCAGAGGCACCAATGCGAGTTCAATGCAGAAAAAGTTGTGCTGAAGCCAAACGTGGATTTGGTCGAGCTGGAAAAGGGCACCAAGAGGGTCAAATACGACTGCCCCACTTGCGGTAAGCAGTTCGTTAGCAAGAATAATTTAGACCGGCATCAGAGTAGCCACGAAAATTCGAAAGCCAACACCTGCGAGCACTGCAACAAACAGTTCGTAAGCGAGAACCGGCTGCGCATCCACAAGGAAAACCATTGCAAGAAAGCGGGGgatatttcaaaattctacCGCAGTGACGTCACTGTTTGGAAATGCGGCAAGTGCCACGAGGTGTTTTCTTCGAGTTCGATGGCGAGCTGTCATCTAGAAACCTGTGACGTCGCCATAGACCTACAGGAAGACCCTAACGAGGTCAAATCAGAGCCCGAGGATTCTCTAAACCAGGTCGAAAAGACCCCCGCTGAAAACAGAACAATCGAAAAAATGTCGACGGAAATCTTGTTGCAATGCGAGTTTTGCAACAGGACTTACGCCGATAAGCAAATTTTGCTCAAGCACCAAAAAACGCACAAAACCGACCAAAACTACCAATGCGTCGTTTGTCGCGAAGCGTTCGATTCGTACGTAATCGCGTCGCAGCATTGGCTCAAAAAATGTTCAGAAAAATCCAACTTGTTCTACCTCCCCAAATTAACTTATTGCGAATTTTGCGACCGCACTTTCAAATCCCACGAAATCCTCTACACgcacaaaatcaaaaagaaacaCTACACCCCCAAGTTACACTTCAAAAATCTCAGCGACGAAACTCCGGAAGTTTCCGTTAACTCAAAACCAGTTAAGAGCGAAGGTGCTATCGATAAAATGATCGAAGATGTTTTAATTGCGCTAGAGATTCCTCTCAATAAGCGCctcaacaaaaatgttgatgaCAACAAGGAAAATGAGGACCCAAACAAAGAAGTCATTGATATCAAAATGGAACCTTTAGCACAATCCAGCAACAACAGCGAAAACTTATCGGAAGAAAGTGTAGACGAGAAGAAGAAAAGGGGGCGCAAAAGGAAATTAGCGAGACCTCAATCCAAAGGAAAAAAAGCTTGTCTCGCGCTGGAGCAGGGGTACAGGTACCAATGCGAAAGATGCGTCACGGTTTGGAGCAGTATCACAGAATTGGAGGCACATAGAGAAAAAGAACATGCGTCCAACTTCAACTGCGATGAATGTGGCCAAGTGTTGCACAGCGCACGCGCCCTCTTGATCCACAGCCGCGCccacaaaagtttgaaacctTATGTTTGCGACACTTGCGGCAGGAGCTACTCGCAAACCTCCCACTTGTGGCAACATATGCGTTTCCACCAAGgCATAAAACCGTTTGCTTGTCCCCACGAGGGCTGCGAAGCTCGCTACACTATTCGTCCGGATTTGAAGGACCACATCAGAAAAGTTCACACTAGAGAGCGCCCCTTCAAGTGCAGCGTTTGTGGCAAATGTTTTTTGACCGGGTCGGTTTACTACCAGCATCGGTTGATACACACGGAAGATCGACGATACGGATGCGATatgTGTGACAAGCGCTTCTTTAGAGCGGACGCTCTGAATAATCACAAAAGGATTCACACCAATGAACGCCCGTATCCTTGTTTTGTTTGTGGAAGATTGTTTAGGCAGAAGGGGGATCGCAACAAACACTTCCGCACCCAGCATCCGGACGCTATTGTTAATTAA
Protein Sequence: MNVIDDKAISVINSHYIRGTDRVFSTRYVADLLTHQLVSKAPILGKNVSFSTSSGVNLALSNLEVDWGSVRVVKMDPSDLARVKAKMNIPCMIRCQNCETNYPTKYQYQRHQCEFNAEKVVLKPNVDLVELEKGTKRVKYDCPTCGKQFVSKNNLDRHQSSHENSKANTCEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCGKCHEVFSSSSMASCHLETCDVAIDLQEDPNEVKSEPEDSLNQVEKTPAENRTIEKMSTEILLQCEFCNRTYADKQILLKHQKTHKTDQNYQCVVCREAFDSYVIASQHWLKKCSEKSNLFYLPKLTYCEFCDRTFKSHEILYTHKIKKKHYTPKLHFKNLSDETPEVSVNSKPVKSEGAIDKMIEDVLIALEIPLNKRLNKNVDDNKENEDPNKEVIDIKMEPLAQSSNNSENLSEESVDEKKKRGRKRKLARPQSKGKKACLALEQGYRYQCERCVTVWSSITELEAHREKEHASNFNCDECGQVLHSARALLIHSRAHKSLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCGKCFLTGSVYYQHRLIHTEDRRYGCDMCDKRFFRADALNNHKRIHTNERPYPCFVCGRLFRQKGDRNKHFRTQHPDAIVN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01283708;
90% Identity: -
80% Identity: -