Spec001156.1
Basic Information
- Insect
- Schizotus pectinicornis
- Gene Symbol
- Zeb1
- Assembly
- GCA_951805265.1
- Location
- OX638202.1:10984860-10986467[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.063 4.3 8.1 0.6 1 23 167 188 167 188 0.93 2 11 0.0091 0.62 10.8 0.8 1 23 229 250 229 250 0.95 3 11 4.9e-05 0.0033 17.9 4.5 1 23 256 278 256 278 0.97 4 11 0.0029 0.19 12.4 2.3 1 23 284 306 284 306 0.98 5 11 4.4e-05 0.003 18.1 4.9 1 23 313 335 313 335 0.97 6 11 0.0022 0.15 12.7 7.2 1 21 348 368 348 369 0.92 7 11 5.7e-05 0.0039 17.7 3.4 1 23 379 402 379 402 0.96 8 11 8.2 5.6e+02 1.5 0.3 6 23 411 428 409 428 0.72 9 11 8.1e-06 0.00055 20.4 1.7 1 23 434 456 434 456 0.98 10 11 5.2e-06 0.00035 21.0 0.1 1 23 462 484 462 484 0.98 11 11 5.8e-05 0.004 17.7 1.2 1 23 490 512 490 512 0.97
Sequence Information
- Coding Sequence
- ATGAGCCTAATTAAGGGCTACGCAACAATCTCCAACGTGAATCAAATATGCAAAGTATGTCTCGAAGAGAAAACCCAAATGCTTCCCTTGGCGTCAACAATGGAATTTCAAAACGTTGAAACTACCGCTATAAGAATCAGTGAAATCCTGGCAAGAATTGTTCCAGAACCAGAAGACGCCAGTAATGGACCAGTCCTAATCTGTGTTGACTGCTTGAATGAACTGAAACCAGTCTACTTATTTATACTGAAATACGAAGAGGCTGTGAGAAATTtacgaaattatttacaatccagtatcaaaattgaagaaaattacgaCGATACCGAAGACTTTGGTTGCACAGATACCATTTGTAGCAGTGATGAAGTAAGAACACAAAAGCAGTATCAAACGCGAAGCAAACAACGAACCAGCAACAAAAAGAAAGTGCGCAAGAGGAAAGTGAAAACAATTGAAAGTGGGAGTGAAAATGAAATATCAAACGATCCAATTTTGCACCCATGCCCAGTTTGCACTAAAGAATTTCCCGCCTTAGAGCTGCGAGACCACGCTCACACCCataaagcattaaaaaaatacctgAGTATCCCCGCGGACAGAAAGGTAACGCCAACATCAAAATTCTACGCTAATCCCTACAATGATAAAGCTTCCTTTTTTAACAatgcaaaaaaacaattgcacaAGTGTCCGTATTGTAATTTAGAGTTTAGTGTGGAAGATTTCCGTTTACACATTGACGTGCATCGCAAACAAAACGAGTTTAAGTGTGACAAGTGCGAACGCGTCTTCAAACGGTTGAACCACCTAAACACCCATCGGGTCAAACATCTGAAAGAATACCCCTACAAATGCGACCAATGCGGCAAAGGTTTTGTTATCAAAACCAACTATGATTGTCACATGCTAACACACACCAATAGCGAGTTGCCTCACGAGTGTCGCTTTTGTTTTAAGCGTTTTTCGAATCCAGAGCACTTGAACCGGCATCAAATTATCCATACGGAAAACGTTACTTATTCAGTTAAGTATCGCGTTTGTAAATGCCACCATTGTCTAAAAACTTTTAAGGACAAAAGCGAACTTAAGGGTCACGTTTGTGTTCCCTTGGAACAGGCAGTTAATACTCGGTTTCCTTGTAAAACGTGCAAGAAGGTTTTTAAACATTCGAGTGGACTTTACAATCACAACCGGAATATTCATAAACTGAAAGGCGCGAAAACTTTGTGTTCGGTTTGTGGAAATTACGTTTCGAACATTTACAACCATATGATGCGGCATACTGGGGAAAAACCGTATCAGTGTCATCAGTGCGATAAAAGGTTTATTGCGAAGCCCCAATTGAAACAGCATTTGTTGGTGCATTCAGGACTTAAACCGTACGTTTGTAGTGTTTGTGCCAAGgcgtttaataatttgtacaATTTGCAAGTGCACGAAAGGATACATAAAGGAGATCGGTGCCATATTTGTCCGATTTGTAGTAAGGGCTTTTTGGAGAAGTCCTATCTTAAAAAACATATGAATGTGCATTCGAAAATTTAG
- Protein Sequence
- MSLIKGYATISNVNQICKVCLEEKTQMLPLASTMEFQNVETTAIRISEILARIVPEPEDASNGPVLICVDCLNELKPVYLFILKYEEAVRNLRNYLQSSIKIEENYDDTEDFGCTDTICSSDEVRTQKQYQTRSKQRTSNKKKVRKRKVKTIESGSENEISNDPILHPCPVCTKEFPALELRDHAHTHKALKKYLSIPADRKVTPTSKFYANPYNDKASFFNNAKKQLHKCPYCNLEFSVEDFRLHIDVHRKQNEFKCDKCERVFKRLNHLNTHRVKHLKEYPYKCDQCGKGFVIKTNYDCHMLTHTNSELPHECRFCFKRFSNPEHLNRHQIIHTENVTYSVKYRVCKCHHCLKTFKDKSELKGHVCVPLEQAVNTRFPCKTCKKVFKHSSGLYNHNRNIHKLKGAKTLCSVCGNYVSNIYNHMMRHTGEKPYQCHQCDKRFIAKPQLKQHLLVHSGLKPYVCSVCAKAFNNLYNLQVHERIHKGDRCHICPICSKGFLEKSYLKKHMNVHSKI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01283696;
- 90% Identity
- iTF_01283696;
- 80% Identity
- -