Sgrm014629.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Schizaphis graminum
Gene Symbol
zfh1
Assembly
GCA_003264975.1
Location
QEWZ01001415.1:17051-195611[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.27 26 6.1 0.2 2 20 171 188 170 189 0.93
2 7 0.03 2.9 9.0 0.1 3 23 212 232 210 232 0.94
3 7 1.6e-05 0.0015 19.4 0.6 2 23 239 260 238 260 0.97
4 7 1.1e-06 0.0001 23.0 4.6 1 23 269 291 269 291 0.99
5 7 4.8e-05 0.0046 17.8 1.5 1 21 297 317 297 318 0.95
6 7 0.00021 0.021 15.8 9.2 1 23 972 994 972 994 0.98
7 7 0.014 1.4 10.1 4.4 1 21 1000 1020 1000 1021 0.96

Sequence Information

Coding Sequence
ATGGAATCACTAACAGAGGACCAGAACAGACCTGTAGAACTTTTGTCACCGTCCAGAGGAAGGAGGAAACAAGCGAAACCTCAGCGGAAAAAtgTGGAAAGCGCAGACTGTGACATTGTAGACCGCCAACAGGATATGACTTTGTGTGTGGAACAAGATGACGAAATTATTATCAATCCGGACACTAATCACAACCATCAGCCGCTGCTGTCGGCGGGTACCAATACCAAACGACAATTCATCAAAAATCGTAGTCAGACGGCTGAAGATACTAAAGATTCTTCTacgtcGGCAAACGAAGATTGTACAAGTAGAGACGATGAAGAGGACATGACGGTAAACGACGAAGGCGATGGCACAGCTGCTGTTAAAGACGATGACGAAGGGGAAATGGCGATCAAGGACTGTGACAAAGTTCCGTTGCCCGGGATGAGCCTGGAGGGCCTTCTCAAAGACTATCAAGACCTACACCAccaacagcagcaacagcagcaacaacaacattTACAGTACTGCCCGTTTTGTCGGGAATCGTTTGACTTGGGATCGCTAAAAGAACACTTAGATGGCGGATGCCGAGCCCGGCCGTCTTCGCCGCCCTCAACCACAGTTGCAATTGCCGGTCAATATGGGTGCTTGCAGTGCAACGCTGCTTTTGGCAATCGTGATCTCCTCGAGAAACATGAACTGCTCCACTCGCCCAACGCCCAAGTGTCTTGTAAGGTGTGCAACAAGACATTCGCCAATGTTTACCGTCTCCAAAGGCACATGATAAGTCACGATGAGAGCGCAGTGCTACGCAAGTTCAAATGTCCCGAGTGTGAAAAAGCGTTCAAGTTTAAACATCATCTCAAGgaACACATTCGCATCCATAGTGGAGAAAAACCGTTCGAGTGTTCCAACTGCGGTAAACGGTTCTCGCATTCCGGTTCATATTCTAGTCACATGACCTCTAAGAAATGTCTGATCATAAATCTAAAAATGGGAGGCCGTGGGTCGCAAGCCAACAACCGAAACGCCGCTCACCATCAACCAAACAACGGTTATCCAAGCAAGCGTTCAGTTcctaacaacaacaacaacataaccaacaacaacagcagcaaccACAACAACAACAGCGTTGGTGCCGGTAGCAATACGTTCTCGCCCCTATTGCCGTCTTCAGCGTCCAAGTACGAAATGCAAGTGGCACAGCCGAGTCCAACACAAGCGCAATCGCTTACACAACAGTCATTCTATCACACACAACCAAAAGCCTCCGCGGCCGCTATTTATTTCCCAGGACTGTTCAACACTCAGAGCAAGTTCAACATACACGATCTTCTGCAACCATCGTTGATGCAGTCGGCGATGGTTAAGCAAGCACAAGAACAGGAACAGGAACAAGAACAAGAAGAACAAAAACAACAGCAAGACGATTGCTGTAGTGGTGACGACAAGAATAAGACGACAGACGACGACCAGAAGGAGCACGAGAGTGGTGGTGAAGACTTCAACGAAGACGACGAGGccgatgacgatgacgacgacaaGTACGACAACGTGATAGACGTGGTGAGCGTAGTGAAGAAGGAATGTGAAGACGGCGGCGGTGCGGACGAGGACACAGCTGGCGAAACAGACGCTGCTGTCAAGAAACTCTTGGAGACGGTCAACGTGTCAGCGGTCACCAAACAGCTGATGATGGCCAACGCTGCGGCCGCCGCAGCCGCTGCCCTGCACCACCAGCAGCACCAGCCGCCGCCGTCTTGCGGCTCGTCGGGCGGTTGCCCTAGTGTGACGAGCGATTCGCCGCCATATCACCACGGGTACAGCCTGTACCCCAATCACAACAACCATCACCACCTCCTCAACAACCATCACAGAGCCGAAGGGCTGGTCGTCAAGGCGGAATACTCGGCGGGCGGTAGTTCCGGGGCCTGCAAGACGAccatcaacaacaacaatataaacAACGGTTACGACGCGGGCAGCGACTGTTACACCGACGACGAGCACAGGCCGTGCACCACCGAAGAGGAAGACTCCGTAGACCAGGACGGCCGCAAGATCCGCGTCCGGTCGCAGATAGCCGACGACCAGCTGGCCGTGCTCAAGGAGTGCTATGCGGCCAACCCGCGGCCAAAGCGCGAGGAACTGAGCCGGATCGCCGACCGGATCGGCTTCAACGTGCGCGTCGTCCAGGTGTGGTTCCAGAACAACCGGGCCCGTGACCGGCGCGAGGGCCGCCTGGTGCACATGCCGTACTCGCCCGcgtccgccaccgccgccgcccaCGCCGCGCCCGTATCGAGCGCCGAACAGCCGCTCGACCTGTCCACGAAGCGGGGACGCCGCGACGACGAGTGCAACAGCGGCCGCAGTTCCGTCTGCAACGTTACGCTGACCAACAAGTGTACCATACAGTTCAAGTGTTGGACCGCCAACAACCGGGACGATTGCAGTTCGTCGCCGCCCGCGTCCATGTTGCAGCCGATGCAGCAGCATTGCCGCAAGACGTTTCTGGGAGGCGCGTACCCGCCGCCGTCACCTGCCTGCGCGGCACCGCCCCCGCCGCCGCCTTCGTCCCACCTGAACCATCCAGCGTCTCACTCGCCCATACCGGCCGTCGCGCTTCGGCACAACGGCAGCTTGAGCCCTGCGTCCGAGAAACGTTCGTGGAAGAGAGAATACGGAGACTGGAGTGACATGACAGACGAAGCCGAAGACTCGGGATGTACATCCCAAGACCCTGACGATGCGGTGTCCACTGGAGCCGGCGCCGGCGCTCtgcacaacaacaacaataacaacaacaaaaacaacaaccACAACACTAGTAATAGCGCAATGGCGGCCGCGGTCGGTTCGCCCAGCAAAAAATCAAAGCCTTCATCCGTGGAATCTGCTGAAGTACCAGATCAAAGACCGCACAAGTGCGACGTTTGCCCAAAAGCTTTCAAACACAAACACCATCTAACCGAACACAAGAGGCTGCACAGTGGTGAGAAGCCGTTCCAGTGTTCCAAATGCATGAAACGGTTCTCGCATTCGGGTTCATACAGCCAGCACATGAACCACCGATTCTCGTACTGCAAACCGTACAGAGAGTAA
Protein Sequence
MESLTEDQNRPVELLSPSRGRRKQAKPQRKNVESADCDIVDRQQDMTLCVEQDDEIIINPDTNHNHQPLLSAGTNTKRQFIKNRSQTAEDTKDSSTSANEDCTSRDDEEDMTVNDEGDGTAAVKDDDEGEMAIKDCDKVPLPGMSLEGLLKDYQDLHHQQQQQQQQQHLQYCPFCRESFDLGSLKEHLDGGCRARPSSPPSTTVAIAGQYGCLQCNAAFGNRDLLEKHELLHSPNAQVSCKVCNKTFANVYRLQRHMISHDESAVLRKFKCPECEKAFKFKHHLKEHIRIHSGEKPFECSNCGKRFSHSGSYSSHMTSKKCLIINLKMGGRGSQANNRNAAHHQPNNGYPSKRSVPNNNNNITNNNSSNHNNNSVGAGSNTFSPLLPSSASKYEMQVAQPSPTQAQSLTQQSFYHTQPKASAAAIYFPGLFNTQSKFNIHDLLQPSLMQSAMVKQAQEQEQEQEQEEQKQQQDDCCSGDDKNKTTDDDQKEHESGGEDFNEDDEADDDDDDKYDNVIDVVSVVKKECEDGGGADEDTAGETDAAVKKLLETVNVSAVTKQLMMANAAAAAAAALHHQQHQPPPSCGSSGGCPSVTSDSPPYHHGYSLYPNHNNHHHLLNNHHRAEGLVVKAEYSAGGSSGACKTTINNNNINNGYDAGSDCYTDDEHRPCTTEEEDSVDQDGRKIRVRSQIADDQLAVLKECYAANPRPKREELSRIADRIGFNVRVVQVWFQNNRARDRREGRLVHMPYSPASATAAAHAAPVSSAEQPLDLSTKRGRRDDECNSGRSSVCNVTLTNKCTIQFKCWTANNRDDCSSSPPASMLQPMQQHCRKTFLGGAYPPPSPACAAPPPPPPSSHLNHPASHSPIPAVALRHNGSLSPASEKRSWKREYGDWSDMTDEAEDSGCTSQDPDDAVSTGAGAGALHNNNNNNNKNNNHNTSNSAMAAAVGSPSKKSKPSSVESAEVPDQRPHKCDVCPKAFKHKHHLTEHKRLHSGEKPFQCSKCMKRFSHSGSYSQHMNHRFSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00018912;
90% Identity
iTF_01304751;
80% Identity
iTF_01328501;