Basic Information

Insect: Scaptomyza tumidula
Gene Symbol: zfh1
Assembly: GCA_035044465.1
Location: JAWNNW010000668.1:1093227-1122397[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0012 0.084 13.4 1.0 2 23 84 106 83 106 0.96

2 9 0.0011 0.077 13.5 0.1 1 23 316 338 316 338 0.97

3 9 3e-05 0.0022 18.4 1.8 2 23 353 374 352 374 0.97

4 9 1.1e-05 0.00076 19.8 6.4 1 23 383 405 383 405 0.99

5 9 0.00031 0.022 15.2 1.2 3 21 413 431 411 432 0.94

6 9 0.028 2 9.0 0.4 2 21 677 696 676 697 0.92

7 9 2.5e-05 0.0017 18.6 0.5 1 23 1041 1063 1041 1063 0.94

8 9 5.2e-05 0.0037 17.6 7.4 1 23 1069 1091 1069 1091 0.98

9 9 0.0026 0.19 12.3 4.3 1 21 1097 1117 1097 1118 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0012	0.084	13.4	1.0	2	23	84	106	83	106	0.96
2	9	0.0011	0.077	13.5	0.1	1	23	316	338	316	338	0.97
3	9	3e-05	0.0022	18.4	1.8	2	23	353	374	352	374	0.97
4	9	1.1e-05	0.00076	19.8	6.4	1	23	383	405	383	405	0.99
5	9	0.00031	0.022	15.2	1.2	3	21	413	431	411	432	0.94
6	9	0.028	2	9.0	0.4	2	21	677	696	676	697	0.92
7	9	2.5e-05	0.0017	18.6	0.5	1	23	1041	1063	1041	1063	0.94
8	9	5.2e-05	0.0037	17.6	7.4	1	23	1069	1091	1069	1091	0.98
9	9	0.0026	0.19	12.3	4.3	1	21	1097	1117	1097	1118	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTTTGGCCAAGAGGATAACATTATAATACAGCAGAGTATGCCATCAACTACAGCCTTCTCCATGCAGTTTTCCTCTTTGGCCTCGAGtttgcatcatcatcaagcCTCTGCGCATAACAGCAAGCCGGCAAACAATAATGTTGCTGGCAGTTTGGAGCATGTGGCACATGCAACCAGTGTTGCCACAACGAATGCAACAATCGATGATTGTATGATCCAGTGTCCGGAGTGTCACAAACGTTTCAACGAGTTTCAGTCGTTTAGTGAGCATATTGCCACAGAGCATCCGCATGACAAGTTGAACTATGAGCATACACATCGTGTGGCAGCTGGGGCAGCTGGGGATGCTAGCGAGCCCGAGGAGGATGAGGAGCAGAGCAATTtgagcagcggcagcaacaacaacaacaacaacaataatcatcGTCATTATGCCAAATctcccaacaacaataacaacaacaacagcaacagcattaacaacaacaatagtgaaACGGCAAAGAATCAAAACAATCGAATCCATTCACATTCACCATCGTGCTCACCGGTTGCCCAGGTTGCGCCCAACGATCTTTTCGCCCACCTGCAGCATCCACCGCCCCAACTGCCCGCCCATCTGCATGCCCAGTTTATGGCTGCAGCCGCCTTGGCAATGCAATCTGCACGCACAGCCAGCTCGCCCAGCCaccagcatcatcatcaccaccaTCCACATCATGCGTcacagcaccagcaccagcaacaaacagcatcacaacagcaacagcagcaacagcaactgttgccgCCGCCAGCACAGCAAGcgggcagcaatagcagcgtTGGCAGCAATTCAGCATACGATCTGGATCTAAGTGCTCATCGTTCCACTTCCAGTCCGGGCTCAACAACAGGCGATCTCAATACCGCCTTTCCCTGCATGCAATGCACCGCTGCCTTTCCCAATCGCGAGCAACTCGAACAACACCAACTGTTGCATTCGCCAACGGGTCCACATGCAACCACACACAATGTGACACAGACTTGCAAAATATGCCACAAAGCATTTGCGAATGTTTATCGACTCCAACGCCATATGATTAGCCACGATGAGTCGGCGCTCCTACGCAAATTTAAGTGTAATCAATGCGATAAGGCGTTTAAGTTCAAGCATCATCTCAAGGAGCATGTTAGGATCCATTCGGGTGAGAAACCCTTTGGCTGCGACAACTGTGGCAAGCGTTTCTCGCATTCGGGCAGCTTCTCCTCGCACATGACCTCCAAAAAGTGCATCAGCATGGGCCTGAAGCTCAACAATAATCGCCAGATGTTGAAGACTCTCGACAAGAATACGGAtcctcagcagcagcaattgcctCAGGGTAAACGCTCCTCGTGTAAACTGATGCCGGAACAGATCCTGCCCAATCCCATGAACTACTTTGCTGGCGATGCTCAGTCGCCCGTTGGAGGAGCAGCAGTTGGCGGCGCTGGTGGAGGCGCTCCACCTCCGCCTCCATTTTATTCCAATTATAGTGCGATGAATGCGGCACTGTTGGCATTCCCAAATGCTTTTATGGCCGCTGCACTCGATCCACGCATGCATCCCTATAGCATACAGCGACTCCTGGAGCTAACAGCTGctggccagcagcaacaacaacagcagcgggaACAGGAAGAGCAACGTGAGCAGGAGCAGCGGGAGGAGGAGCTTCTGCCCAGCAAGGATGAGGATGAGACACCCGATGAGCCAAAGCTGATCATGGATCTGGAATCCGAGCCTGAGATGATGAGCAGCAAGCCGGCAGCTACTCCCCAGCCAAGTCCTGCCACTGTCAAGCAGGAGCCGAGTCGGGAGCCAACGCCTCTGCCGGAGGAACATGCACCCCAAACACCCAAATCCATTAAACAAGAGCAGGAGCacgtggaggaggaggaggagcagcagcagcagcagcagcagcaggaacatgTTGAGGAGCAGGAGGATTCCATGCAGGAGGCGGATCTTCGCTGTAGTCGCTGTGCCAAGCAATTCAATCATCCCACAGAGCTTGTGCAGCACGAGAAAGTGCTCTGCGGTCTGATCAAAGAGGAACTGGAGCAACActaccaccaacaacagcaacaacaacagcagcagcagcagcaacaaaatacgAGCTTTGTGCTGCCTTCTGCCAGTGAGGCAGATGAGGAGGACGATGAAGAGGTGGAGGAGGAGCCACGTCAGGATTACCATGCCGGAAGCAGCGATAGCGGGGAGCGAAAAGTACGCGTCCGCACCGCCATCAAtgaggaacagcagcagcaacttaaGCAACATTATGCCCACAATGCTCGACCCAGTCGCGATGAGTTCCGACGGATTGCCGCCCATCTTCAGCTGGATGCGCGTGTCGTCCAGGTTTGGTTTCAGAACAATCGTTCCAGGGAACGTAAGCTTCAGAGTTATGCTGCCGGCAGCAATGAGGCAGCAACTACTGTAGCCTTGTCCACTCCTAGTGCTGCACTGCCTCCTCCGCCGCCGGCCATGCGTGCTGGCGGTGAGGATCAGCCACTGGACTTGTCCGTCAAGCGGGATGCAACACCTcctctgcagcagcagctgcagcaacagcagcagccgatgCAGCTACCCAATGATTATCCTGAAGCAATGGCTATTAATCTCAGTCGCAAGCTATCCAGCTCTGCGTCCATGTCGCCAGCTTCCCTGTCACCGGCAGCAGCGGGTCTCTACTTTGCGCCACCATCGCCGCCCAACATGCACGAGGTGACGCCTCCGATGCCACCACGTTCGGCACCCTTTCCCGGCCTACCTCACTTCCCGATGATGACCCGTCTGCCAATGGAGGCACTTTTCCAGATGCGTCCCGGCGGCGACTATGCACCCAATCCTCTGATGAACAGTATTAAGCTGCCTGACTATCGCGGCACCAGCCTCAGTCCCGGTGGCTCCGAGAAACGTTCGTGGCGCGACGACGATTCGCGCATCTCCCACGAGGATGATTATGTTTTGGCTAGTGCGGGACTTTTACCACCCAAGCCCAAGCGTGCCAAGGCCGAAACCCATGGACATGCCGGTGATCCCGATCTACCTTTCATCTGTGACCAGTGCGACAAGGCCTTTGCCAAACAGAGTTCCCTGGCCAGGCACAAGTACGAGCATTCCGGTCAACGACCGTACCAGTGCATGGACTGCCCGAAAGCCTTCAAGCACAAGCATCATTTGACGGAGCACAAGCGTTTGCATTCCGGCGAGAAGCCATTTCAATGCTCCAAATGCTTGAAGCGTTTCTCCCACTCCGGCAGCTACAGTCAGCACATGAACCACCGTTACTCGTACTGCAAGCCGTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIIQQSMPSTTAFSMQFSSLASSLHHHQASAHNSKPANNNVAGSLEHVAHATSVATTNATIDDCMIQCPECHKRFNEFQSFSEHIATEHPHDKLNYEHTHRVAAGAAGDASEPEEDEEQSNLSSGSNNNNNNNNHRHYAKSPNNNNNNNSNSINNNNSETAKNQNNRIHSHSPSCSPVAQVAPNDLFAHLQHPPPQLPAHLHAQFMAAAALAMQSARTASSPSHQHHHHHHPHHASQHQHQQQTASQQQQQQQQLLPPPAQQAGSNSSVGSNSAYDLDLSAHRSTSSPGSTTGDLNTAFPCMQCTAAFPNREQLEQHQLLHSPTGPHATTHNVTQTCKICHKAFANVYRLQRHMISHDESALLRKFKCNQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRQMLKTLDKNTDPQQQQLPQGKRSSCKLMPEQILPNPMNYFAGDAQSPVGGAAVGGAGGGAPPPPPFYSNYSAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQQQQQREQEEQREQEQREEELLPSKDEDETPDEPKLIMDLESEPEMMSSKPAATPQPSPATVKQEPSREPTPLPEEHAPQTPKSIKQEQEHVEEEEEQQQQQQQQEHVEEQEDSMQEADLRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQHYHQQQQQQQQQQQQQNTSFVLPSASEADEEDDEEVEEEPRQDYHAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRRIAAHLQLDARVVQVWFQNNRSRERKLQSYAAGSNEAATTVALSTPSAALPPPPPAMRAGGEDQPLDLSVKRDATPPLQQQLQQQQQPMQLPNDYPEAMAINLSRKLSSSASMSPASLSPAAAGLYFAPPSPPNMHEVTPPMPPRSAPFPGLPHFPMMTRLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVLASAGLLPPKPKRAKAETHGHAGDPDLPFICDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01321430;
90% Identity: iTF_01327792;
80% Identity: iTF_01327792;