Basic Information

Insect: Scaptomyza polygonia
Gene Symbol: zfh1
Assembly: GCA_035044585.1
Location: JAWNNU010000906.1:1825225-1851975[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0042 0.46 11.6 1.0 2 23 85 107 84 107 0.93

2 9 0.0011 0.12 13.5 0.1 1 23 323 345 323 345 0.97

3 9 3.1e-05 0.0034 18.3 1.8 2 23 360 381 359 381 0.97

4 9 1.1e-05 0.0012 19.8 6.4 1 23 390 412 390 412 0.99

5 9 0.00032 0.035 15.2 1.2 3 21 420 438 418 439 0.94

6 9 0.029 3.2 9.0 0.4 2 21 675 694 674 695 0.92

7 9 2.5e-05 0.0027 18.6 0.5 1 23 1046 1068 1046 1068 0.94

8 9 5.4e-05 0.0058 17.6 7.4 1 23 1074 1096 1074 1096 0.98

9 9 0.0027 0.29 12.3 4.3 1 21 1102 1122 1102 1123 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0042	0.46	11.6	1.0	2	23	85	107	84	107	0.93
2	9	0.0011	0.12	13.5	0.1	1	23	323	345	323	345	0.97
3	9	3.1e-05	0.0034	18.3	1.8	2	23	360	381	359	381	0.97
4	9	1.1e-05	0.0012	19.8	6.4	1	23	390	412	390	412	0.99
5	9	0.00032	0.035	15.2	1.2	3	21	420	438	418	439	0.94
6	9	0.029	3.2	9.0	0.4	2	21	675	694	674	695	0.92
7	9	2.5e-05	0.0027	18.6	0.5	1	23	1046	1068	1046	1068	0.94
8	9	5.4e-05	0.0058	17.6	7.4	1	23	1074	1096	1074	1096	0.98
9	9	0.0027	0.29	12.3	4.3	1	21	1102	1122	1102	1123	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTTTGGCCAAGAGGATAACATTATTATACAGCAGAGTATGCCATCATCCGCAGCCTTCTCCATGCAGTttTCCTCTTTGGCCTCAAGTttgcatcatcatcaacaagtTGCCTCGGCGCATAATAGCAAGCCTTTAAGCAATGTGGCTGGCAATTTGGAGCATGTGGCACATGCAAACAGTGTTGCCACAACGAATGCCACAATCGATAGCTGTATGATACAGTGTCCGGAGTGCCACAAACGCTTCAACGAGTTTCAGTCCTTCAGCGAGCATATTGCCAATGAGCATCCGCATGACAAATTAAACTATGAGCATACGCATCGTGTGGCAGTTGGGGCAGCTGATGCTGCTAGCGAAGTTGACGAGGATGAGGAGCAAAGCAATctaagcaacagcagcaacaacaataatcgTCGCTATGCCAAATctcccaacaacaataataacattaacattaacaacaacaacagcgaaacagcaaaaaatcaaaataatcatACGTCAGCATCGCATTCGCCATTGTGCTCACCGCTTGGCCAGGCAGCGGCGGCGACGGCGGCGGCAGTGGCGGCGCCGAACGATCTATTTGCCCACCTGCCGCATCCACCACCGCAGCTGCCACCGCATTTGCATGCCCAATttatggcagcagcagctttggCCATGCAATCAGCTCGCACCGCCAGCTCACCCAGCCACCATCAGcagcaccaccagcagcaccatcatcatcatcatcaccaccAACTCcagcatcatcagcaacattcgtcacaacagcaactgttgcCACCACcacagcagcaccaacagcagcaacagccaccGGGCAGCAATAGCAGCGTTGGCAGCAATTCGGCATATGATTTGGATTTAAGTGCTCATCGTTCCACATCGAGTCCGGGCTCGACAACAGGTGATCTCAACACCGCCTTTCCCTGCATGCAATGCACCGCTGCCTTCCCAAATCGCGAACAGCTCGAGCAACATCAGTTGTTGCATTCGCCAACGGGGCAACATACAGCAACACAAAATGTTACACAGACATGCAAAATTTGCCACAAAGCATTTGCAAATGTTTATCGACTGCAACGCCATATGATTAGCCATGATGAGTCGGCGCTGCTTCGTAAATTCAAGTGTAATCAATGCGATAAGGCATTCAAGTTCAAGCATCATCTCAAAGAGCACGTTAGAATCCATTCCGGTGAGAAACCCTTTGGCTGCGACAATTGTGGCAAGCGTTTCTCGCATTCTGGCAGCTTCTCATCCCACATGACCTCGAAGAAGTGCATCAGCATGGGCCTAAAACTGAACAATAATCGCCAAATGTTGAAAACTCTTGATAAAAATACGGatccacagcagcagcagcagcagttgcctCAGGGCAAACGCTCCTCATGTAAACTAATGCCGGAACAGATTCTACCCAATCCCATGAATTACTTTGCTGGCGATGCTCATGCGCCTGTTGGACAggcagcagttgttgttggtgttggtggaGTTGGTCCTCCTCCGCCTCCATTTTATTCCAATTATAATGCTATGAATGCGGCTCTGTTGGCATTTCCCAATGCCTTTATGGCCGCTGCACTCGATCCACGCATGCATCCCTACAGCATACAGCGACTCCTGGAGCTAACAGCTGctggccagcagcagcagcgtgaAGAAGAGCAACGGGAGCGGGAGCACGAGCAGCATGTGGAGCTGCTACCAAACACCAAGGATGAGGATGAGACACCGGATGAGCCCAAGCTGGTAATGGATCTTGAATCGGAATCGGAGTTGATGAACAACAAGCCGGCAGCTACGCCCGAGCAAAGTCCTGCCGCTGTCAAGCAGGAGCCAAGCCGGGAGCCAACACCTCTGCTGCCAGAGGAACCAAGCCAGTCACCCAAATCTATTAAGCAAGAGCAGGAGCAAGTGGAGGAGCATGCGGAAGAGCAGGAGCAGGAAGAAACCAACCAGGAGACGGAGTTGCGCTGTAGTCGCTGTGCCAAGCAATTCAATCATCCCACAGAGCTTGTGCAGCACGAGAAAGTGCTCTGCGGCTTGATCAAAGAGGAACTGGAACAACATTaccatcagcaacagcagcaacaacaacaacaacaacagcaacaacaacaacaacaacaacaacatcaagctGGCTTTGTCCTGCCTTCGGCCAGTGAGGCAGATGAAGAAGACGAGGATGAGGATGTGGTGGGTGAGGAACCACGTCAGGATTACCATGCCGGCAGCAGTGATAGCGGGGAGCGCAAAGTACGCGTTCGCACTGCCATCAACgaggagcaacaacaacagctgaaaCAACATTATGCCCACAATGCTCGACCAAGTCGCGATGAGTTCCGTCGGATTGCCGCCCATCTTCAGCTGGACGCACGTGTTGTCCAGGTTTGGTTTCAGAATAATCGTTCCAGGGAACGCAAACTTCAGAGCTATgaggcagcagcaactgttgctatTCCTTCTACAAATGCTGCACTGCTGCCTTCTCTGCCGCCGCCGTCGATGTCGTCGTCAGCCATACGTGCTGCTGGTGAGGATCAGCCATTGGATTTGTCTGTCAAACGGGATGCAACACCGCCTCCAatgcaacaacatcagcaacagccgATGCAGCAATCCAACGATTATCCCGAAGCTATGGCCATTAATCTTAGTCGCAAGTTGTCCAGCTCGGCATCCATGTCACCAGCTTCGCTGTCGCCTGCAGCAGCGGCTATTTACTTTGCGCCACCCTCGCCGCCGCAAGAGGTGACGCCTTCCATGCCGCCTCGATCGGCACACTTTCCCGGCCTGCCTCCCTTTCCGCTGATGGCACGTCTGCCCATGGAGGCCCTCTTCCAGATGCGTCCCGGTGGTGATTATGCACCCAATCCTCTGATGAACAGTATTAAATTGCCCGACTATCGCGGCACCAGCCTCAGTCCCGGTGGCTCCGAGAAACGCTCCTGGCGCGACGATGATTCCCGCATCTCCCATGAGGATGATTATGTTTTGGCGAGTTCGGGACTCTTACCACCGAAACCAAAGCGTGCCAAAGCCGAGACCCATGGACATGCCGGTGATCCCGATCTGCCCTTCATCTGTGACCAATGCGACAAAGCTTTTGCCAAACAGAGTTCCCTGGCCAGGCATAAGTATGAGCATTCCGGTCAAAGACCGTACCAGTGCATGGATTGCCCAAAAGCCTTCAAGCACAAACATCATTTGACGGAACACAAACGTTTGCATTCCGGCGAGAAACCATTTCAATGCTCCAAGTGTTTGAAGCGTTTCTCCCACTCCGGCAGCTACAGTCAGCACATGAACCACCGTTACTCGTACTGCAAGCCGTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIIQQSMPSSAAFSMQFSSLASSLHHHQQVASAHNSKPLSNVAGNLEHVAHANSVATTNATIDSCMIQCPECHKRFNEFQSFSEHIANEHPHDKLNYEHTHRVAVGAADAASEVDEDEEQSNLSNSSNNNNRRYAKSPNNNNNININNNNSETAKNQNNHTSASHSPLCSPLGQAAAATAAAVAAPNDLFAHLPHPPPQLPPHLHAQFMAAAALAMQSARTASSPSHHQQHHQQHHHHHHHHQLQHHQQHSSQQQLLPPPQQHQQQQQPPGSNSSVGSNSAYDLDLSAHRSTSSPGSTTGDLNTAFPCMQCTAAFPNREQLEQHQLLHSPTGQHTATQNVTQTCKICHKAFANVYRLQRHMISHDESALLRKFKCNQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRQMLKTLDKNTDPQQQQQQLPQGKRSSCKLMPEQILPNPMNYFAGDAHAPVGQAAVVVGVGGVGPPPPPFYSNYNAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQQREEEQREREHEQHVELLPNTKDEDETPDEPKLVMDLESESELMNNKPAATPEQSPAAVKQEPSREPTPLLPEEPSQSPKSIKQEQEQVEEHAEEQEQEETNQETELRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQHYHQQQQQQQQQQQQQQQQQQQHQAGFVLPSASEADEEDEDEDVVGEEPRQDYHAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRRIAAHLQLDARVVQVWFQNNRSRERKLQSYEAAATVAIPSTNAALLPSLPPPSMSSSAIRAAGEDQPLDLSVKRDATPPPMQQHQQQPMQQSNDYPEAMAINLSRKLSSSASMSPASLSPAAAAIYFAPPSPPQEVTPSMPPRSAHFPGLPPFPLMARLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVLASSGLLPPKPKRAKAETHGHAGDPDLPFICDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01321430;
90% Identity: iTF_01326293;
80% Identity: iTF_01326293;