Spar001921.1
Basic Information
- Insect
- Scaptomyza parva
- Gene Symbol
- topi
- Assembly
- GCA_035044645.1
- Location
- JAWNNT010000065.1:1934387-1935707[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.82 55 4.5 1.9 1 23 127 149 127 149 0.93 2 9 0.00056 0.037 14.4 3.3 1 23 155 179 155 179 0.97 3 9 0.0021 0.14 12.6 3.5 1 23 186 211 186 211 0.96 4 9 0.00013 0.0085 16.5 0.8 1 23 220 242 220 242 0.97 5 9 1.5e-05 0.00098 19.4 1.7 1 23 250 274 250 274 0.96 6 9 0.00026 0.017 15.5 1.1 1 23 280 302 280 302 0.98 7 9 0.0001 0.0069 16.7 1.1 2 23 309 331 308 331 0.96 8 9 0.00023 0.016 15.6 0.9 1 23 337 359 337 359 0.97 9 9 5.1e-07 3.4e-05 24.0 0.6 2 23 366 387 365 387 0.98
Sequence Information
- Coding Sequence
- ATGCGAGAGGTGCCCATGCTGGCGCACAAGTTTACCACCTGTACAGTTTTGTCCATCGATGAGGATGAGCGAGTGCCCAGCAAGCTGTGCACGGAGTGCTACACAAATTTGAATGAATTGTATGCATTTCGAGCCAAGTGCATTGCTTCTGATATATACTGGCGCAAGGAGCAAGAAAACTGTAAGGTTAATGCGCCCCAAGATGTGGACTTCACGGACATGGAGAAAAAGCCTCCCAAAAAGATTCCACTCCGGCGAAGTAAAAAGCAATCCACGCAAAAGAATGAAATAGAGAAATCCGAATCAGAAACAGAATTCGAATACAAGGATGCCATAGAAAATGAAGagAccacacaaagcaaacaaactgcAACAAGCTACAAGTGTGACATTTGCAGCAGCCGTTTTTTGGTGGAGCATCGTCTTTTAGCGCACAAGCGTCAACATGAAGGACTCATGCCATATCCGTGCACGGAAGACGGCTGTGAGCGCGCCTTTAATCGTCGGCACTGCTTGACGGAGCACCAAAAGCAGCACTCGGGCACTAGCCGCTGGTTCAGTTGTGAGCAGGAGGGCTGCCCCAAACAGTATCGCCACAGACCCACGCTTATAATGCACCAGCGCAAATGCCACAACATGGGACCAGAACTGAAGTCCCACATATGTGAGTTTTGCGGCAAGATCTTTAGTTCCACGGCAGTGCTCAACGATCACCGTCtaacacacagagacatatCAGAGCTGCCGCATCCATGTCAAGAGGCCGACTGCTCGAGACGCTTCTCCAGCAAAGAGAAGCTAAAGGTGCACATGATGCGTCATGcgggtataaaaaattttcGCTGTCCGTATTGTGGCATGCGCAAGACGACAAGAAATGAGCTAAAGATACACATAAACTATCACACATTGGAGCGCACCTGGCCCTGTCGCTTCTGTTCGAAGGTGTGCAACAGCTCTGGCAATCTCCAAATGCATGTGCGCACCGTGCACGAGGGTGCCAGAGATTACGCGTGCAGCTACTGCGATCGCAGCTTCGCCAAGGCGGACACTCGCAAATATCACGAGATGACCCACACCGGCGAGAAGCCCAACAAGTGTGAGGAATGCGACAAACGCTTCACCCAACCAGCCGCATTACGCACCCATCGAAAGATACACGAGCGGCAGCGCAAGGAAACGGAGGCAAGGTCAACGGCATATACAATAGTCATAACTGCACCAGCCGATGTAGCTGATATTGGCGTTATACAAACATTATAG
- Protein Sequence
- MREVPMLAHKFTTCTVLSIDEDERVPSKLCTECYTNLNELYAFRAKCIASDIYWRKEQENCKVNAPQDVDFTDMEKKPPKKIPLRRSKKQSTQKNEIEKSESETEFEYKDAIENEETTQSKQTATSYKCDICSSRFLVEHRLLAHKRQHEGLMPYPCTEDGCERAFNRRHCLTEHQKQHSGTSRWFSCEQEGCPKQYRHRPTLIMHQRKCHNMGPELKSHICEFCGKIFSSTAVLNDHRLTHRDISELPHPCQEADCSRRFSSKEKLKVHMMRHAGIKNFRCPYCGMRKTTRNELKIHINYHTLERTWPCRFCSKVCNSSGNLQMHVRTVHEGARDYACSYCDRSFAKADTRKYHEMTHTGEKPNKCEECDKRFTQPAALRTHRKIHERQRKETEARSTAYTIVITAPADVADIGVIQTL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01321375;
- 90% Identity
- -
- 80% Identity
- -