Basic Information

Gene Symbol
-
Assembly
GCA_035044645.1
Location
JAWNNT010000127.1:1718731-1723953[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.00063 0.042 14.3 1.9 1 23 228 250 228 250 0.97
2 26 0.029 1.9 9.0 2.8 1 23 256 278 256 278 0.98
3 26 0.096 6.4 7.4 2.5 2 23 309 330 308 330 0.96
4 26 0.021 1.4 9.5 0.6 1 23 404 427 404 427 0.93
5 26 0.72 48 4.7 0.4 2 22 439 459 438 459 0.94
6 26 3.3 2.2e+02 2.6 0.4 1 20 468 487 468 489 0.89
7 26 0.1 6.8 7.3 0.4 2 23 503 524 502 524 0.97
8 26 0.078 5.2 7.7 0.4 1 23 598 621 598 621 0.95
9 26 0.0049 0.32 11.5 0.0 1 22 630 651 630 651 0.96
10 26 0.017 1.1 9.8 1.0 1 23 660 683 660 683 0.96
11 26 5.3e-05 0.0035 17.7 0.4 2 23 704 725 703 725 0.97
12 26 7e-06 0.00047 20.4 6.1 1 23 731 753 731 753 0.99
13 26 0.0082 0.54 10.8 1.3 1 23 840 863 840 863 0.94
14 26 0.0027 0.18 12.3 1.3 1 22 870 891 870 891 0.96
15 26 0.083 5.5 7.6 0.5 1 23 900 923 900 923 0.91
16 26 6.8e-05 0.0045 17.3 1.9 1 23 949 971 949 971 0.97
17 26 2.4e-05 0.0016 18.7 3.0 1 23 978 1000 978 1000 0.98
18 26 0.006 0.4 11.2 0.0 2 20 1027 1045 1026 1047 0.93
19 26 0.0036 0.24 11.9 2.2 1 23 1092 1115 1092 1115 0.96
20 26 0.0081 0.54 10.8 2.0 1 23 1152 1175 1152 1175 0.96
21 26 0.0037 0.25 11.9 1.4 1 23 1197 1220 1197 1220 0.97
22 26 1.3e-05 0.00085 19.6 0.1 2 23 1241 1262 1240 1262 0.95
23 26 4.3e-05 0.0029 17.9 2.9 1 23 1268 1290 1268 1290 0.99
24 26 4.7e-06 0.00031 21.0 1.9 1 23 1296 1318 1296 1318 0.97
25 26 2.5e-07 1.7e-05 25.0 2.3 1 23 1324 1346 1324 1346 0.99
26 26 0.00064 0.043 14.3 0.3 1 21 1352 1372 1352 1376 0.91

Sequence Information

Coding Sequence
atGGTGCTAACGAATTATTGTCGCACATGTGCGCTACAAGATGACAATTTATTGGCTCTGGCATCGTGCAGTAAAAAATACCCTGAGAAAAGTATTTGCGACATGTTGCAAGAACTAACACAAAACGATCCTCTGTTGGAGCACTTAGATGATGATATGCCACAGCGTCTGTGCGGCTCATGTTTGAATCAGCTGGAAGCTGCCTATGCATTTGTGCTGCAGGCTCGCCAGGCTCAGAAGCGACTGTTAATGCAACTACATAAAGGATTACAGACAAAATGTCTTGAAGAAATACCTATAGATATAACACTGGAGCACATCAAAACCGAAGCGGACATGGACCCAGATCCAAAGACTAACACAGAAATTAGTGAGCAATTGGAGGACGCTGATGCTAATATGGAGgaggagaaagagaaggaggtTTCTGTTGAAGGTGTCACTGCCTTTAAATGCCCACCAACAAGTTATTGCGATAGCAGTGAAGAAGACTTAGATAACGACGATGTTGTTTTCACGCCACCGCAGCTTAGGCGCAGTGCACGGCGAGTCAAACGTAGTACTATTGGCGAAAATGAGTCCACTTGTGACCAAGCATCCAATCTTCAGACACTAGCCAAGCGTGGTCGCGGCCGTCCTGCACGcccaaacaaaacagagaCCATTAACGAGGATGGCCGGCACATGTGTAAGGTGTGTGGCAAGACGTATTCGTGGTATCGCGACTTACAGCGCCATGAACGCATACATTTTGAACAAGCGACCTACGTGTGCGAGCGTTGCGGAAAGAAATTCTTACGCAAGGATAAGTATATGTTCCATTTGCGAACGCATGAGAAACACGTTAAACTGCAGACGCTGCAAGTGGCCAGTGAATGGCGCTACGCTGAGCGACTCTACAGCTCGGGTTGCCTGAAGCGTGTAGAGTGCAAGTTGTGCGGTCTGAAGTGCCACCGCATACAGGAATTACGTCAGCATTTAGCAAGTCATGCTAATATTGAGACACTGTCAAATCTCAGTTTGGACAATGATGTCATCAGAGAGCAATTTGGTAGCCAATGGGATTTGGAACACATCAAGCAACAGGTGTGCTTGCAAATTGCGAAAGGAGGCGACGAGCTGGAGAACTTCTGTGCTATTGTAAATGCCTACGGTTATGAGCTGTGCCTAAGTGACTCGGATGAGGAGTTGCCAGACGTACCCTCTCAATATCAATGCCTGCCCTGCAATGCCAGTTTCACACGCAAATATCGCCTCATACAACACACCTTGGAGGATCACACGCAACCGAACGTAACAGAAACGCCTTGGGTTCGCTGCAATATCTGCCAAATTGGCTTTGTTTGCATCAAACTTCTGGAGCAACATCAGCGCACCCAGTGCCTCAATCCGCTGAAGCGTTACAGCTGCAACAATTGTCCCGGCAAATTCATTTGGCTTCAAAATCTACAGGAACACGCGTGCAGTAGACTGCAACAGGATCAACCAAAGGATTACAGCAAAGTTCAGTGTTGTCTATGCGATGCCAAACTAAGCAGCATGGCAGCTTTGCGATCCCATGTACTGACCCATCGCGATGGACACACTGGCATCGATCCACAGCAACACGCCGCCTTCTTTCGCACCTATTATCGGGATGATGTCGATTGCAGTCTTACAGAGCTTCGGGCACGCATCGCTGGCGACTTTCAATCACAAAATTATGGACGCTACTTTAATGCCTGCACGGGCAGCGGCCATGAATTGGACTTCAATGATTCCGACACTGCTTTGAGCGATGCACCCACTCTGCACACCTGTGAGGTGTGTGGCGAAACTACAGAACTTCTCGTTCAGATGgaacaacatcagcaaaacCAGCACAAGGAGTTGGGTAAAATAATGCCTTATATCTGCACTGATTGTGGGTTGGGTTTTGTGGCCGAAGCGTTGCTTCAGCAACATCGTCGTCGTAtttgtggcaagcagcaagccAAATACAATTGCGCCGAATGCAGTCAACGTTTTTACTGGCTCTCCAACTATGAACGACACATGCAGTTGAAGCATGGGGTTGAGCATACGGACGAGGCTCAGATTCAGAAACACAAGCGGCAAACATCAAAGTTACAGTGCACCGAATGCGACAAGgtaTTTATCTGGCCCAAGGATCTGACGCGGCACAAGCGCATGCATCAGTCACAGGTGCAGTTTCAATGCAACTTTTGTGAGCGCAAGTTTCATCGTAAGGATAACCTCAAGTCGCATATGCGAATGCACAAGGAGCAACAGTTGGATGCGTCAACCCTGTCGACCAGTGAGCAACAGGACGTAATGCAGCAGCGCATGCACGTGGTGTTGAGCCACTTTTGCCGTCCTCACGGCTGTAAGACTGATATAGCCAATGATGAAGAATTGGAAAGATTCATTTCGATTACCAACGAGGCGGGCATTGAGTTGAGCTTAGATAGCAGTGAAACAGATACGGATTCGGATTCCGATTTCGCAGACAATAAGCGGAGCAGCAGTGGGCGCCAGTACGACTGTGAGCTGTGCCAGCTTCGTGTGACACGCAAGCATCAGCTCTATGCCCACCAGCTGGAGCAGCACACGTGGAAGCAGGGAGCACACGTTTGCAGCTACTGCCAAGCAAGGTTTGTGAATGAACAGCTGCTGGAGCATCACTATCGCACTCTCTGCCGTAATGGCCAACGTCGTTTTCTCTGTCGCAAGTGTCCATTACGCTTTCGTTGGCGCGACAATCTTAAGCTACACACTGACGTTGCGCATGAGGATGGGAACACACTAGACCAGTCGAACATGGACACTCAGCTGAATGGTTCAGGAATGCTGCCGATGGTTAGTTACGACTGTTTAGAGTGCAAACGTAgcttcaaaatgcaaaaggaTCTCACAAGGCATACCCTAATGCATACCCAGGATTCGAGCATCTATCGTTGCCATTGGTGTGCACGTCGTTTCTATCGCCAGTCAAATCTGTTGCAGCACATTGAACGTCATGGCATCAGCGCCGATCAGCTGCCCTATGCGGAGGCCCTGCTGAATGCCAGTCGGCATCCACATGGCCAGAAGTGCATTCAGTGTAAGGTGTGCGAAATATCCTTTACCAGCATTGCGGCATTGCGTTCCCATCTGGCATCAGCCCCAGTTGGCACACATCATGCAATTGGATCTATGCTCAACTATTCTATTACTGATCAGTTGGGCTATGAGCTGCACTTGGAGGACTCGGAAACGGATGAGGAGACCAAGCCGGGGGGTACGCCATCGCACTACACCTGTGGCATGTGCCAGCTGCGTTGTGTGCGCAAATTTGAGCtccaacagcatcagcaggcCATGCATCGTCTAGAGCGAATCAGTGAGGGATGCGAGGTGTGCATTTTTAAGAGCGTGTCGCCAGATGTGATTGCCCATCATCGGCGAATATTGTGCGGCAACACGGAGAAACAGTTCAAGTGCTCAAAGTGTAGCTACCGATTTATGTGGCAGTCGAATCTGGATCAGCACATGCAGCTACAGCATCCCAGAAGCGAGGAGCCAACTGTCCTGCCCGTGCCGGACACTGATAACTCCAAGAGCCAGATCTTCCAGTGCGGTCAGTGTCCCAGTAAATATAATCGCAAGGATCGTCTGACGGCGCATGTGAAGAGATTCCATGCAGATGGTGCTATGGCCTCCAAGAAGTCACCAGCGACTGCCAAGCAACAAAAGAGTTTCTTGTGCGCTTTCTGTGGCAAAGCCGTGAGCTCCTCGTCGAATTTAATTATACACATACGTCGGCACACGGGAGAGAAACCATTCAAGTGCGATTATTGTGACATGGCCTTTCCACGTTCCTCCGATCTCCAGTGccacagacgcacacacactgggGAGCGTCCTCATGTTTGCACCGTCTGTCAGAGGGGTTTCGCTCGCTCCTACAAGCTTCAGCAGCACATGCGCATCCACAATGGCGAGCGACCCTACAGGTGTACCTACTGCGAGAAAAGCTTCACCCAATCCAATGATTTAACGCTTCACATACGACGACATACGGGCGAACGTCCCTATCAGTGCAATACGTGCGGCGAGAGATTTATTCAGGGCACAGCCCTCAAAAATCATCGACTACAAAGTGGTCACATGGAAACGGATGTCGAACAAGCAAAAATTGACTGA
Protein Sequence
MVLTNYCRTCALQDDNLLALASCSKKYPEKSICDMLQELTQNDPLLEHLDDDMPQRLCGSCLNQLEAAYAFVLQARQAQKRLLMQLHKGLQTKCLEEIPIDITLEHIKTEADMDPDPKTNTEISEQLEDADANMEEEKEKEVSVEGVTAFKCPPTSYCDSSEEDLDNDDVVFTPPQLRRSARRVKRSTIGENESTCDQASNLQTLAKRGRGRPARPNKTETINEDGRHMCKVCGKTYSWYRDLQRHERIHFEQATYVCERCGKKFLRKDKYMFHLRTHEKHVKLQTLQVASEWRYAERLYSSGCLKRVECKLCGLKCHRIQELRQHLASHANIETLSNLSLDNDVIREQFGSQWDLEHIKQQVCLQIAKGGDELENFCAIVNAYGYELCLSDSDEELPDVPSQYQCLPCNASFTRKYRLIQHTLEDHTQPNVTETPWVRCNICQIGFVCIKLLEQHQRTQCLNPLKRYSCNNCPGKFIWLQNLQEHACSRLQQDQPKDYSKVQCCLCDAKLSSMAALRSHVLTHRDGHTGIDPQQHAAFFRTYYRDDVDCSLTELRARIAGDFQSQNYGRYFNACTGSGHELDFNDSDTALSDAPTLHTCEVCGETTELLVQMEQHQQNQHKELGKIMPYICTDCGLGFVAEALLQQHRRRICGKQQAKYNCAECSQRFYWLSNYERHMQLKHGVEHTDEAQIQKHKRQTSKLQCTECDKVFIWPKDLTRHKRMHQSQVQFQCNFCERKFHRKDNLKSHMRMHKEQQLDASTLSTSEQQDVMQQRMHVVLSHFCRPHGCKTDIANDEELERFISITNEAGIELSLDSSETDTDSDSDFADNKRSSSGRQYDCELCQLRVTRKHQLYAHQLEQHTWKQGAHVCSYCQARFVNEQLLEHHYRTLCRNGQRRFLCRKCPLRFRWRDNLKLHTDVAHEDGNTLDQSNMDTQLNGSGMLPMVSYDCLECKRSFKMQKDLTRHTLMHTQDSSIYRCHWCARRFYRQSNLLQHIERHGISADQLPYAEALLNASRHPHGQKCIQCKVCEISFTSIAALRSHLASAPVGTHHAIGSMLNYSITDQLGYELHLEDSETDEETKPGGTPSHYTCGMCQLRCVRKFELQQHQQAMHRLERISEGCEVCIFKSVSPDVIAHHRRILCGNTEKQFKCSKCSYRFMWQSNLDQHMQLQHPRSEEPTVLPVPDTDNSKSQIFQCGQCPSKYNRKDRLTAHVKRFHADGAMASKKSPATAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQRGFARSYKLQQHMRIHNGERPYRCTYCEKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQSGHMETDVEQAKID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-