Basic Information

Insect: Scaptomyza pallida
Gene Symbol: zfh2
Assembly: GCA_018152965.1
Location: JAECXP010000010.1:355498-373225[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0054 0.4 11.3 0.4 1 22 82 103 82 106 0.91

2 9 4.2 3.1e+02 2.2 0.4 1 21 258 279 258 280 0.88

3 9 1.2 89 3.9 1.9 1 23 301 325 301 325 0.91

4 9 0.087 6.4 7.5 0.7 1 23 564 587 564 587 0.97

5 9 0.13 9.9 6.9 1.4 2 21 782 801 782 805 0.89

6 9 5.8e-05 0.0043 17.5 2.3 1 23 856 878 856 878 0.98

7 9 0.0065 0.48 11.0 2.9 2 23 885 907 884 907 0.94

8 9 0.0003 0.022 15.3 1.7 1 23 1627 1649 1627 1649 0.97

9 9 0.0035 0.26 11.9 1.3 1 23 1764 1786 1764 1786 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0054	0.4	11.3	0.4	1	22	82	103	82	106	0.91
2	9	4.2	3.1e+02	2.2	0.4	1	21	258	279	258	280	0.88
3	9	1.2	89	3.9	1.9	1	23	301	325	301	325	0.91
4	9	0.087	6.4	7.5	0.7	1	23	564	587	564	587	0.97
5	9	0.13	9.9	6.9	1.4	2	21	782	801	782	805	0.89
6	9	5.8e-05	0.0043	17.5	2.3	1	23	856	878	856	878	0.98
7	9	0.0065	0.48	11.0	2.9	2	23	885	907	884	907	0.94
8	9	0.0003	0.022	15.3	1.7	1	23	1627	1649	1627	1649	0.97
9	9	0.0035	0.26	11.9	1.3	1	23	1764	1786	1764	1786	0.97

Sequence Information

Coding Sequence: ATGCAGGAGCTTAACAGTTCACAAAACATTGTGGCTGTTGCAGCAGCAGCAGCAGCAAACGCCAAACTGATTCTACCCAGTCCGTCCCCTCAAGGATCTAGCGGGAGTGGGCCGGGTATAGCCATCGCATCCGCAGTTGGATCGCAACAGCAGGCGCCTGGCGCTAGCTGCACCACTAGTAATGCGTCTGGTACAGCTGGCGGACCAACAGTTTCGTCGGCGTCCATTAAGCCGAAGCCATCGTTTCGTTGCGATATCTGTAGCTATGAAACATCTGTAGCCCGCAATCTTAGGATTCACATGACCAGTGAAAAGCATACACACAACATGGCTGTGCTCCAGAACAACATGAAGCATATACAAGCGTTAAACTTTTTGCAACAGCAACCTGGAGTTGGAGCTGGAACTGGATCCGGAGTTGGAGGGAGCAATGCCAATAGTTTTCTCCCACTGTCAGAAGTTGCTTTAGCTGATTTAGCCTATAATCAGGCACTCATGATTCAGTTAATACAACAAAACGCTGCCAGCGTCCTGCATCAACAGCAGCATCAACAACAGGTGTCTTCCAGCTCCAAATTGTCGCCAACGTCGCCTTCGACAGTTAGCACGCCCGACCATTTACATGCATCATCGTTTTCGTTTTCACCAAAACTGATAAAACATCCTCAAGTTGTGGGAATGGGATTTGGAGAGTCAGCGGTGGCATCAGGCGCGGCTGATACGCAGGACACATATGCGGATAGCTTGCCGGAATTGTGGCCAACCGCATTGTACAGCTGTTTGATTTGCGATTGTTTTAGCACAAGTAATATTGATGAACTTAATCAGCATTTGCTGATGGATCGCTCCAGGCAATCATCAAGCGCATCCACCGACGTTATGGTTATACACAACAATAACTATATATGCCGCTTGTGCAACTATAAAACGAATCTAAAAGCTAACTTTCAGTTACATAGCAAAACGGACAAACATTTGCAAAAGCTCAATTTGATCAATCACATTCGCGAAGGCGGCACTCGCAATGAATACAAGCTTCAAAATCAGCAGCTTGCCACAAATGTTGTGCAGGTTAAGTGCAACTGCTGCAACTTTCACACTAACTCAATTCAAAAGCTGTCGCTGCACACGCAACAGATGCGACACGACACAATGCGCATGATTTTTCAGCACTTGCTCGCAATAGTTCAACGAAGCCGTCTAAGCTTAGAGAGAGGGTCGCCATTATTAGTTGACGATCAGGATCAGCAACCCAACCAAACCTTACCAAAGAAGTCTCTATGTTGCCAGCTTTGTAATTTTGTTGCAAAAAATCTATACGAAATGGTCCAGCATGTAAAAGGATTAAGACACTTGCAGATTGAACAATTTGTTTGTTTGCAACGCCGTAGTGAAAATTTGGAAATGCTCGAACTTAACGAAGTTTTTAAAATGACCGAACAACTACCGGGCAGCACTGAAGATTCAAGCGTTGATTGTAGTCTCACCCTTGGAAATGATAGTTCCGCTGGTGCACCACCAGAAAAGGCACTTGGTGTGGCGGGTTGTTCATTAACATCCGAAAGTCATATGTTTTCGCCTGCTTCTGCCTCCAGTTGCTCGACGACATGTGGCAAAGGTCTGCCGCCTGTTTCATCACCGTTACCACCAACGTTAAGCGACTTACATTTAAACGTGACAACAACAGTTTTCAAATGCAATCTATGTGAATATTTTGTGCAATCGAAAAAGGACATGGAAAGTCACATTGTGACTATGCATCCATCGGCAGAAAGCGACGACTTTATCAGCATACCGACTAACACAGCTGCTCTGCAAGCTTTCCAGACAGCTATCGCAGCCGCTGCTCTTGCTGCCGTACAACGTTGTAGCGTTGGCGATAAGATGGCTACACCTGCAGGAGAACAAGGAAACAGCAATGGCGATGGTGACAGCGACTGTCCTGTTGATATTAAGCGAGAACGACTAGAAGAGAACGATTATGGAAGCATAATAATGACTAGTGCAGATGCTTTGGAAAGTAGTAATTTTATGGAAGTGAGCGATGCCAAAAAGAAGACTGAATCGGTTGCGCCAGCATCAGGTGTATCGTGTCCTTTGTGTCTGGATAGTGGCTATAGTGAGAAATCGCTATTAGAGAATCATTTAGTAAGCGTGCACAGCGTGACACGAGATGGCCTTGCCAGACTTCTACAGCTGGTAGATCATACCGCTTGGCGACCAGGAAATATTGACGACATTTCACCATCAACTGCATCCACCAACGAACAAAATCTAGAGGAAAGCAAGTGTTTAAATGACAACGAATCAAATATATCAGCCGCTACAATTTCAGCAGGCGCCTCATGCCAACAGTGCAATGCAAACTTCAAACATGAGGAGCAACTGCTTCAGCATGCTCAACAATCGCAACACTTTCCCATGCAAAATAACGAATACCTTTGCCTTGCTGTTAGTCAGGTTACCCGTCCCTGCTTTTTGACCTTTTCCAATTTGCCGGCAATGATTGCACATTTCAAGGACTTGCATATGAGCTTGGTTATCTCCGAGCGACACGTCTACAAGTATCGCTGCAAGCAGTGCTCACTGGCTTTTAAAACACAAGAAAAGCTAACTACTCATATGTTGTACCATAGTATGCGAGATGCTACGAAATGCTCCCTTTGCCAACGCAACTTTCGAAGCACGCAAGCCCTGCACAAGCATATGGAGCAGGTTCACACAGCGACAGAAGCAGAAGCGGCTGCTGGTTTAACTAGCAGTCCTCGGGATATGTCGCCATGTTTCAGGTCAACAGATCGAGCAAAGACGCAGCATGAGCAAAATGCTTTTGACTTATCTACATCCAGGACGAGTGCTTTGGCTGTCCAAAGCCAAGACAATTTGCATCAATCCCTCCCGCAATCATCCCTTCAACTAGATGATCCACAGTTGAAAAATTCGCAGCAACTCTCCGATGTGCTGATATCGCCAAACGTCCTTGAAGAACCGTCTACAGAGCAGCAACAACAGCATTTAGCTGTACTGACCGCAGCATTGCTTAAACAACAGAGTTCTCACGACGCAGTTAGCCAGTCGACTGATGGTCAATTATCCTTGTCGCCAATCGAATTGCATCAGTTGCAGTTAAAGGCTCAACAACAACATGGCTCGTTTAGCAATATAAACCAACAATCGCCGCTACACAATCTGCATAATCTTCAAAACTTGCAACAGCTGCAACAACAGTTAAGCGCAGCAGCATCATCCACTGGGATGCCTATTAATCCGGTAGAGATGCTAAATATTATGCAATTTCACCACTTGATGTCATTGAATTTTATGAATTTGGCACCACCATTGATCTTTGGGGCCAATGATGCCAGCGGCGCTGCCGGAACTGGGGCAACAGTTGGCGTTCAGAACAATGGTGTTGCGTCATGCTCATCAGCAAGCTCTTCCATTGTTTGTATATCGGATAATCAGCAGAAATGTACGGGTAGTCAGCAAACAAGTGACACAATGAATATAAATATCCTTGCGCCGTCACATCAAACCAATAATAGTCAGCAACAGCTTAGTAGCAATCAGAAACGTGCGCGCACCCGCATAACCGATGACCAGCTAAAAATTCTGCGAGCTCATTTCGATATAAACAACTCACCGAGTGAAGAGAGCATTATGGAAATGTCACAGAAAGCCAATCTACCAATGAAGGTTGTTAAGCATTGGTTTCGCAACACTTTGTTTAAAGAACGACAACGAAACAAAGATTCGCCGTACAATTTTAATAATCCGCCTTCAACCACATTGAACATTGAGGAATACGAACGTACTGGCCAAACCAAGGTTACGCCCTTAAATGAGACTGCTACTGCTCATACCGCTGCTTCTGACGTTATTACTGCATCGACGCCAGCTCCAACAACACCTGTCCAAAAATTAATCAATCATAAATCTTTAACATCTACAACAACTGCAGCAAATGCCTTTCTTACAACGACAGAAAATTCGTCTGAGAACATGTCAGACTATTTAAAAGAGCAGTCTGATGTAATGGCAAACTCCAAATTGGAGCATGACTATTTGGTGGGTGGCTTTCCGTTGCCGTTGGATGTGCAGATAAAGTCTGAACCGCATGTTAATGACATTGAAAACGCTACCGCCAGTAATTTTACTATTCACAAAAAGCAATGCCAACTGCAACAGCAAGAGGAAGTGATTGAGTTTATTAAGCAACAACAGCAAAATAGCGATGCAACTGATGGAACACAACCATCACATCAAAATGCTGATGACCAGCCGATGCAGCATGTTGGATCTGGTTCGCATCACCAAGTAAACCAGCAGCAGCAAACGCAACAGACTTGCTGTTACGAAACAAAGTCAGAAAGCGGCAGTTCTGATGTCCTTTCACGCCCCCCAACCCCGAACAGCGTAGCCGCCAACAATTTGTATAGCAGCATGAACGATTTACTAAGTCAACAGCTGGAAAATATGGGTAGCAACATGGGTCCACCAAAGAAACTGCAAATATCGAGTAAATCATTTGATAAACTATCCGTTTCAGGATCAGGAATAATGTCATCATCGACTGCATGTACGCAGCTAGAAAGCAACTCTTCAAACTCATCCAACTCTTCATCGACGTCAGGTGGTAAGCGAGCGAATCGAACGCGCTTTACGGACTATCAAATCAAAGTACTACAAGAATTTTTTGAAAATAATTCGTATCCCAAGGACAGTGATCTTGAATATTTGAGCAAGCTGCTGCTGCTATCGCCACGCGTCATTGTTGTTTGGTTTCAAAATGCCAGGCAAAAGCAACGTAAAATCTACGAAAATCAGCCAAACAATTCGCTTTATGAAAGCGAAGAGACTAAAAAGCAAAACATTAACTACGCCTGCAAAAAGTGTAGCTTGGTTTTTCAGCGTTACTACGAGCTTATCAGACATCAAAAAAACCACTGCTTTAAGGAGGAGAATAATAAAAAGTCCGCAAAAGCCCAAATTGCTGCAGCGCAAATAGCACATAATTTAAGCTCCGAAGATTCAAATTCATCAGTGGATATCCACCATACCGCAGGTACAACTTTACCGCCACAAAATGTTGCAACTGTTGTTGCGGCTGCTGCTGCCTCTGTTGCCCACTCTGGAGGAACCCACCCGTTCGGGTCATCGCCCTCACCTCAGCATTTATTTAGCAAATCGTCATCGCTTACGGATTTTAGTCCCTCAACGACACCAACGCCACCACAGCCACCACAGCGAGAACGCAGCAACAGTTTGGATCAACAGCGATTGCCCAAGTTTGATTGTGACAAGTGCGAACTGCAATTTAATCATTTGGAGCTGCTGCGCGAGCATCAATTAATGCATCTAATGAGTCCGGCACTCTTTGCTGCTGCTGGCCAGCACTCAGTCAGTCAGTCAGAAGGAAGTTATGGTCCATTTGGCAGCATATTGCAAGGCTTGCAGCAGGCAGCGGCCCAACAACAGCAACAACAGCAACAACAACAACAACAGTCACAACCGACCCCAGCAAAAAGGAGAAAATTCTCGGAAAGCTCGTCAAATGCAGAGGAAGGAACATCAATGGGTCTCTTTGAAAGTTCGCATAAAAAATACGAGTTCCTTTTTCAATACTTTTTGCAGCATGAAACCAATAACGAAGTCAAACAACAGTTCTTAATACAGCAGCAAAAGCAACAAGGAAATGGTACAGATTTGGAAATGGAATTTTTAAGCAATTTTTATCAGCAAAATGAATTGAATAAGGGTAGCAGCTACGATTTTTTACTTCAATATTATCGCAAGAATGAAGATAACTTAAAGCACCAGCAAATGTCTTTTAGCTCCAGCAAAAAACCAACAATTGAATTTCTTTTACAATACTATCAGCTCAACGAGTCTAAAAAGTTTTTTCAGTTAGCTGCCTCGCCTCAAACAATACATGATGATAGCATCGAATTGCAACCGTCGTTGCAGCAGCCGAACGCGACGGCGGATGATAAAAAAAACATCGGCAAACAAGATGGTGATATTAAAGCGAGTGAACAGGATATCAAAATTGATGATTCTCTGCATGATTCAATATTATTTTACACAAAAGGGGGGACAAATATCGAAGAAGAGGGAAGCGGTCAAATTCTAAATACTAAAAACGGAATGTGTACACCTAATGTAATTGTACCTAAAGACCTCGATAAAAAACTTAACAATAACAATCACATTAACAATAATGTTAGCTTACACGATGCATGCCAAGAACAATTTGATTTCAGGGAGACAAAAGAAAATGAAAGTGATCGTGAAGGTCCTAAATTATCCGGAACGAATGAAGCAATCAGTGAAAGAAAATCGCATTACTTTCAAAATCTCGAAGATTTTCTTGATGCAACGATGATTGAGAACAACTCTCAAATGCTGACATTCAATGATGACGACAAATCCCAAAACACAACCGCTGAGAGCGCCAACTTATCCTCCGTCAACACTAATGACTGTGTGCCCTCTTTAGACTCGTCGATTCAATTGACTGCTCCGTCATCTAAACAAAACAAGCGACTGCGGACTACAATACTTCCAGATCAATTGAATTTTTTGTATGACTGCTATCAAACTGAGTCCAATCCCAGCCGTAAAATGCTCGAGGAGATTTCGAAAAAAGTTAATCTTAAAAAGCGAGTCGTACAAATTCTTCCTTCCTTCTGCAACATACATTTCCAAAAAAAGCCATTAAACTATATTAAACTATAA
Protein Sequence: MQELNSSQNIVAVAAAAAANAKLILPSPSPQGSSGSGPGIAIASAVGSQQQAPGASCTTSNASGTAGGPTVSSASIKPKPSFRCDICSYETSVARNLRIHMTSEKHTHNMAVLQNNMKHIQALNFLQQQPGVGAGTGSGVGGSNANSFLPLSEVALADLAYNQALMIQLIQQNAASVLHQQQHQQQVSSSSKLSPTSPSTVSTPDHLHASSFSFSPKLIKHPQVVGMGFGESAVASGAADTQDTYADSLPELWPTALYSCLICDCFSTSNIDELNQHLLMDRSRQSSSASTDVMVIHNNNYICRLCNYKTNLKANFQLHSKTDKHLQKLNLINHIREGGTRNEYKLQNQQLATNVVQVKCNCCNFHTNSIQKLSLHTQQMRHDTMRMIFQHLLAIVQRSRLSLERGSPLLVDDQDQQPNQTLPKKSLCCQLCNFVAKNLYEMVQHVKGLRHLQIEQFVCLQRRSENLEMLELNEVFKMTEQLPGSTEDSSVDCSLTLGNDSSAGAPPEKALGVAGCSLTSESHMFSPASASSCSTTCGKGLPPVSSPLPPTLSDLHLNVTTTVFKCNLCEYFVQSKKDMESHIVTMHPSAESDDFISIPTNTAALQAFQTAIAAAALAAVQRCSVGDKMATPAGEQGNSNGDGDSDCPVDIKRERLEENDYGSIIMTSADALESSNFMEVSDAKKKTESVAPASGVSCPLCLDSGYSEKSLLENHLVSVHSVTRDGLARLLQLVDHTAWRPGNIDDISPSTASTNEQNLEESKCLNDNESNISAATISAGASCQQCNANFKHEEQLLQHAQQSQHFPMQNNEYLCLAVSQVTRPCFLTFSNLPAMIAHFKDLHMSLVISERHVYKYRCKQCSLAFKTQEKLTTHMLYHSMRDATKCSLCQRNFRSTQALHKHMEQVHTATEAEAAAGLTSSPRDMSPCFRSTDRAKTQHEQNAFDLSTSRTSALAVQSQDNLHQSLPQSSLQLDDPQLKNSQQLSDVLISPNVLEEPSTEQQQQHLAVLTAALLKQQSSHDAVSQSTDGQLSLSPIELHQLQLKAQQQHGSFSNINQQSPLHNLHNLQNLQQLQQQLSAAASSTGMPINPVEMLNIMQFHHLMSLNFMNLAPPLIFGANDASGAAGTGATVGVQNNGVASCSSASSSIVCISDNQQKCTGSQQTSDTMNINILAPSHQTNNSQQQLSSNQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNIEEYERTGQTKVTPLNETATAHTAASDVITASTPAPTTPVQKLINHKSLTSTTTAANAFLTTTENSSENMSDYLKEQSDVMANSKLEHDYLVGGFPLPLDVQIKSEPHVNDIENATASNFTIHKKQCQLQQQEEVIEFIKQQQQNSDATDGTQPSHQNADDQPMQHVGSGSHHQVNQQQQTQQTCCYETKSESGSSDVLSRPPTPNSVAANNLYSSMNDLLSQQLENMGSNMGPPKKLQISSKSFDKLSVSGSGIMSSSTACTQLESNSSNSSNSSSTSGGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNNSLYESEETKKQNINYACKKCSLVFQRYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAHNLSSEDSNSSVDIHHTAGTTLPPQNVATVVAAAAASVAHSGGTHPFGSSPSPQHLFSKSSSLTDFSPSTTPTPPQPPQRERSNSLDQQRLPKFDCDKCELQFNHLELLREHQLMHLMSPALFAAAGQHSVSQSEGSYGPFGSILQGLQQAAAQQQQQQQQQQQQSQPTPAKRRKFSESSSNAEEGTSMGLFESSHKKYEFLFQYFLQHETNNEVKQQFLIQQQKQQGNGTDLEMEFLSNFYQQNELNKGSSYDFLLQYYRKNEDNLKHQQMSFSSSKKPTIEFLLQYYQLNESKKFFQLAASPQTIHDDSIELQPSLQQPNATADDKKNIGKQDGDIKASEQDIKIDDSLHDSILFYTKGGTNIEEEGSGQILNTKNGMCTPNVIVPKDLDKKLNNNNHINNNVSLHDACQEQFDFRETKENESDREGPKLSGTNEAISERKSHYFQNLEDFLDATMIENNSQMLTFNDDDKSQNTTAESANLSSVNTNDCVPSLDSSIQLTAPSSKQNKRLRTTILPDQLNFLYDCYQTESNPSRKMLEEISKKVNLKKRVVQILPSFCNIHFQKKPLNYIKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324718;
90% Identity: iTF_01324718;
80% Identity: iTF_01324718;