Basic Information

Insect: Scaptomyza graminum
Gene Symbol: PRDM1
Assembly: GCA_018901835.1
Location: JAEIFL010000243.1:8455739-8459903[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2.5e-05 0.0016 18.5 2.5 1 23 820 842 820 842 0.99

2 5 7.5e-06 0.00049 20.2 5.1 1 23 848 870 848 870 0.98

3 5 1.6e-06 0.0001 22.3 4.3 1 23 876 898 876 898 0.98

4 5 0.00052 0.034 14.4 2.4 1 23 904 926 904 926 0.97

5 5 8.9e-05 0.0058 16.8 0.1 1 22 932 953 932 953 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2.5e-05	0.0016	18.5	2.5	1	23	820	842	820	842	0.99
2	5	7.5e-06	0.00049	20.2	5.1	1	23	848	870	848	870	0.98
3	5	1.6e-06	0.0001	22.3	4.3	1	23	876	898	876	898	0.98
4	5	0.00052	0.034	14.4	2.4	1	23	904	926	904	926	0.97
5	5	8.9e-05	0.0058	16.8	0.1	1	22	932	953	932	953	0.96

Sequence Information

Coding Sequence: ATGCGTGAGGAGGACTTTGAGCGTTTAGCGGTGTATCTGGTGCCCGATGTGCAAGCGGAGCGTGGTTTGCCCAATCGTGCCGATAAAACGTTGCCGCGCAGCCTAACGCTAAAGTCCTCAATGGTCTATTCAACGCCAAATGTTAAGACTGAAGGAGTTTGGAGCAGCGGCGTCATACCGCGTGGCACTCGCTTTGGCCCATTCGAAGGCATTCCAACCTCAAATTATCCAAATGATAAGAATAAGGCGCGCTATTTCTGGCGGGTGCAGGGAACACGCCACATAACTTACGGGATTATTAAGATCTTCAAGGATGATGATTATTACTATCTGGATGGCTCGGATCGCTCCGAATCGAATTGGATGCGCTATGTGGCCTCGGCATATAGTTTATCCGTTATGAATCTAGTGGCGTGCCAGCATCAGGATAACATATATTTCTACACCACCCGCGACATACTGCCCAATGAGGAACTGATGGTCTGGTATTGCAAAGATTTTGCCAGTCGCCTCGGCTACGATGTGGATCCCGAGCGCACCATCTTTGGAGCCTGCAAACAGGATGTGGATGTCGATGAGGATGAGGATGATGAGCTGCCGCACAAGAAGCCCCATTATGCAATGCCCGCTCCCGAAATACCTCCCGAGATTGCTGTTAGTCACATAACCTATGTAATGGGCCTACATCTGCCTGGTGCACCACCTCCACCACCATCCACAACAGCTGGATCAGCTGGTGTTTCCTCTGCTCCGACTGCGCAAACACACGCCCAATGCTGTCGTCGTGGCAGTCCACCCGCCCATGTCAGCACCACCACCACCACCGCCAACAGCAGCAGCACAACCATCAGCTCCAATTCCCTACATCCGCATATACAGCATATACAGCACAGCCGACATGCTTCCGTAATCATTGGCCAGGATCGTTCTCCCCTGAATAGCAGCTGTGAAAAGGATACAGCGGGTTCACCACTCTGTGGCAAGGATGCCCATTACGAGCATCAGCTGACGCCACAGGATGGCAGCGTGCGTTCGGTAAGATCCGATGAGGGTTACCACAGCAACGAGTGCCAGGAGGATGGACTGACACCACCCGAGGATTCCAGTGATAGCGAAAGTGAGCACAACTATGTGCTTGACTGCTCCAAGAAGGCGATAGCTCCCAAGGAGACGGTCATTGCGCAAGCACAAAAACCCAACAGTGGGACACCACCAGCGACAGCAAACAACAACAACAACAACACCAGTAGCACTAACAGCTGCACAAACAACAGCAACAGCATCACACCCACCGCTGCCATTGCCACGCCCAGCTGTGAGGCGGATAAGAATGAGTATCGCAAGTTCAAGGTAAAAATGCCACTCAAATATGAGTTCAAGAACAAGAGCTGTGTGAAGACGGAACCAATCAAGGATGTGGATGGGCAATTGCCACCAGTGGGTGTCGGTCTAGAGGAGGAGGATCTACACGAGCTGCATGGAGCAGCAAGTGTGCACTGTGAGGACTCATTATGCCCGCCCAGCACAACTACAACCCTTGGCGAAGAGCACCACCAGCTGCAGCATATCGTAGAGCCAACAAATCCACAACCTGCCTCCTCCACAGTGATTGTGCTGGAGCACAGTTCAAATGGACAAACCCGAACCATTGTGCCGTTGAGTAAACCCTACTATGAAGCCGATCCGCCCGTGGAACGCTATGTGCGCTTCGCACAACCCAGCTCGAGCATCTTGGAGACGATACTTACCAGCCAGCACCGTTTGGAAGCAGCTGCTGCCGCAGCAAATGCTTGCAGGCAAGCGAATGCCGCCACACCGCCACCCACATCACCCACGGAGATGGCCTACAGCTATAAGAAATCCCAGCGTTATGGCAATGCAGTAAGTCCCGATTCCAGCTCGAATCTGGGACAGCCGCAGGAGCTAACCAGTGCACATGTGGTGCAGGAGCAGGAACTCACACTGAGTCGTGGTGCACTGATCAAGGGTGAATGCTCGCCACCACCTCCAGCCTCTCATCATCATCACAATGTGATCTACTCGCCAACAAGGACACATCATGGTGGCTACGAAACGGGCAGCCATTCACCCAACTACGCTGGCTATACGGGTTATCCGGGCGCACAATCGTTGCATGCGGCAACCTCAACGTTCCATTCGCCGCCACACAGTTCCCATTCTCCGTTCGATCGCCAATCGAATGCTTCGAGTGGTGGAGGATCTGCTTCCAACTTGCATCTGTTGCAGAGCAGCACACAAATGTTGAATCATCCGTTGATGCAACCACTGACACCGCTGCAACGTCTCTCCCCATTGCGCATCTCCCCACCCAGCAGTCTGAGTCCCGATGGAAATTCCTGTCCACGCAGTGGAAGTCCCCTGAGTCCCAATTCACTAGCTTCACGTGGCTACCGTTCACTGCCGTATCCGCTGAAGAAGAAAGATGGCAAAATGCATTACGAGTGCAATGTGTGCTGCAAGACATTCGGACAGCTAAGCAATCTTAAGGTCCATCTACGCACCCATTCCGGCGAACGTCCCTTCAAGTGCAATGTGTGCACGAAGAGTTTCACCCAGCTGGCTCATCTGCAGAAGCATCATTTGGTGCATACGGGCGAGAAGCCGCATCAGTGTGATATCTGCAAGAAACGCTTCTCCAGCACATCCAATTTGAAGACCCATCTGCGACTGCACAGTGGACAGAAACCCTATGCCTGCGATCTGTGTCCACAGAAGTTTACCCAGTTTGTGCATTTGAAGCTGCACAAGCGTTTGCATACGAACGATCGGCCGTATGTGTGCCAGGGTTGTGATAAGAAGTATATCAGTGCATCTGGTTTGAGGACACACTGGAAGACGACCAGCTGCAAGCCCAACAATCTGGAGGAGGAACTGGCCATGGCAGCAGCAGCAACTTCTGAGTGTTTGGACAAGGATCTACCGGAGCCGGACTCGCGTGAGGCCTATGAGCAACTGCAGCAGCACATGCATCCAGTGCATCCTAGTTTGCGTCATCTAGCAGGCGCACAATCGCCACCACGTCTCATTCCATTGGGCAGCAATGGACAGCCTCATATGCATCTGCAACAGCATTCACATCCTACCCCACCAGGACACTTAATGCATTCGCCACACGGTGGTCAACCTATGCTGCTGACCACAGCCAATCAATTGCCGCCACCAACAACGCCACATCACATGCAACAACAGCAACAGCAGCAGCAGCAACAACCACTTCCACAAGTCTCGCCCGGCAGACAGCAGCAACATTTGGCTGCAGCTCATCATTTGGCACAACATTCACCCAAGTCACTAAAGCCTCTGCCGGACAATGGCTATCTGCATGGACCACATGTGCAGACGCAGGAGAATCGACCATCGGTCATTGAATCCTCCAGCCAGCCCATGATAATTGAGTGCACGTAG
Protein Sequence: MREEDFERLAVYLVPDVQAERGLPNRADKTLPRSLTLKSSMVYSTPNVKTEGVWSSGVIPRGTRFGPFEGIPTSNYPNDKNKARYFWRVQGTRHITYGIIKIFKDDDYYYLDGSDRSESNWMRYVASAYSLSVMNLVACQHQDNIYFYTTRDILPNEELMVWYCKDFASRLGYDVDPERTIFGACKQDVDVDEDEDDELPHKKPHYAMPAPEIPPEIAVSHITYVMGLHLPGAPPPPPSTTAGSAGVSSAPTAQTHAQCCRRGSPPAHVSTTTTTANSSSTTISSNSLHPHIQHIQHSRHASVIIGQDRSPLNSSCEKDTAGSPLCGKDAHYEHQLTPQDGSVRSVRSDEGYHSNECQEDGLTPPEDSSDSESEHNYVLDCSKKAIAPKETVIAQAQKPNSGTPPATANNNNNNTSSTNSCTNNSNSITPTAAIATPSCEADKNEYRKFKVKMPLKYEFKNKSCVKTEPIKDVDGQLPPVGVGLEEEDLHELHGAASVHCEDSLCPPSTTTTLGEEHHQLQHIVEPTNPQPASSTVIVLEHSSNGQTRTIVPLSKPYYEADPPVERYVRFAQPSSSILETILTSQHRLEAAAAAANACRQANAATPPPTSPTEMAYSYKKSQRYGNAVSPDSSSNLGQPQELTSAHVVQEQELTLSRGALIKGECSPPPPASHHHHNVIYSPTRTHHGGYETGSHSPNYAGYTGYPGAQSLHAATSTFHSPPHSSHSPFDRQSNASSGGGSASNLHLLQSSTQMLNHPLMQPLTPLQRLSPLRISPPSSLSPDGNSCPRSGSPLSPNSLASRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPQKFTQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTHWKTTSCKPNNLEEELAMAAAATSECLDKDLPEPDSREAYEQLQQHMHPVHPSLRHLAGAQSPPRLIPLGSNGQPHMHLQQHSHPTPPGHLMHSPHGGQPMLLTTANQLPPPTTPHHMQQQQQQQQQQPLPQVSPGRQQQHLAAAHHLAQHSPKSLKPLPDNGYLHGPHVQTQENRPSVIESSSQPMIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610151;
90% Identity: iTF_00498390;
80% Identity: -