Basic Information

Insect: Scaptomyza graminum
Gene Symbol: Bcl11a
Assembly: GCA_018901835.1
Location: JAEIFL010000001.1:16051192-16068913[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 8.8 5.7e+02 1.1 0.1 2 11 35 44 34 47 0.85

2 7 0.02 1.3 9.4 2.4 1 23 309 332 309 332 0.95

3 7 8.9e-07 5.8e-05 23.1 1.5 1 23 621 643 621 643 0.98

4 7 0.0095 0.62 10.4 4.7 1 23 649 671 649 671 0.99

5 7 8.8e-07 5.7e-05 23.1 3.2 2 23 952 973 951 973 0.97

6 7 1.2e-05 0.00075 19.6 3.3 1 23 979 1001 979 1001 0.99

7 7 2.1e-05 0.0014 18.8 0.4 1 22 1009 1030 1009 1030 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	8.8	5.7e+02	1.1	0.1	2	11	35	44	34	47	0.85
2	7	0.02	1.3	9.4	2.4	1	23	309	332	309	332	0.95
3	7	8.9e-07	5.8e-05	23.1	1.5	1	23	621	643	621	643	0.98
4	7	0.0095	0.62	10.4	4.7	1	23	649	671	649	671	0.99
5	7	8.8e-07	5.7e-05	23.1	3.2	2	23	952	973	951	973	0.97
6	7	1.2e-05	0.00075	19.6	3.3	1	23	979	1001	979	1001	0.99
7	7	2.1e-05	0.0014	18.8	0.4	1	22	1009	1030	1009	1030	0.97

Sequence Information

Coding Sequence: ATGTACAACAAAGTGCTGTCGATCAGTGAGGATCATGGATTCCGTTCACTGAGCCATTCCGACTCGACAGAGAACGATGCGGTTGCCGCGCAGGACATCCTCACATGCGGCGCCTGCCACAAGACCTTCGCACTGTCGGACATTGTCCGTTTCATACAGCACAAGGTGCTGCAGTGCAACAAGGAGAACTATGGCCAGTGCACGACACAGGCACCGAGCATGGATCGCGATGCCGACGAGGGTCGACCTTTGAGTCTGGTCAATCGTCGTCCCTCGATATCGGCGCCCATAACTGGCCGCAAATCAGCGCCATCGCTTTCCACTGCCGGCAGTGGCGCCACAGTTGCGGCACAGTCAGCTGCTGCAGCTGCTGCTTCTGCTTCGGCCAATGCTGCGGCTGCCACAGCGGCTGCTGCGGCGGCTGCTGCTGCCGCCGTTGCAAGCAGCGCGGCAAGCGGCTCACGCATCCATACACCACCGCCGAGTCCAGCGGATCTGCTTGCCGATGGCGCCAGCAGTACGCCCAAGCGTCTCGTCGACGAGAACGACAATACAACGCCAAAGGCAGAGAGCGATGCGCTAACCAACACTGCCACTGGTGGTGGTGCAACACTTGAAACGAGCAACGCTCACAGTCCACAGGATCAGCGGATTGGACGCAGCGACGAGTGCACGTTGCACGACGACAAGCCAAAGGTCAAACAGGAGCCCTATGCCGATGACGATGATGATAATGAAGATAATGATGAGCAGCAACATCATCTAGACGAAGAACTACAACTAGATCAGGATCCGGAGCGGGAGGAACGTGAGCTGCTGACACAAACAAACACAGACACCGAATGCTCACAGCCGCTGGCCAAGCGACCCAAAATGGAGCTTGTCGATGCCGAAGCGAACACAGTGCATACAGAACCCAGCAATTATACGTGTTCAACGTGCAAGACCCGTTATACATCCGCGTGGCGCCTCATACAGCATGTGCAACATTCGCATGGCGTCAAAATCTATGTGGAAGCGGGCGGTTGTGCGCCACCGGATTCCCTGCATCCGAATCCCTTCCAGCTGCTGCGCATGCCGCTGCCACCAGCGCTGTCGCAGAGCAATGTAGTTCCTAGCGTGTCGCCGCTCTTTGGCCGCCCCACGCCCGCCGATCACTATCGCATGGAGCAGCTGGTTAGCGAACAGTTTCGGCACCATGGCTTCAATCTAGCCGCTGCCGCTGCTGCTGCCCAGGCTCAATTCAATGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGTCCGGCTGGTAGTTTGAATTTGGAACCGCAACAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCGGGCACAACAAGCCCTGGAGCTGGCAACATTGTTAACTCGAGCTCGCCGAGTCCAAGACAGAAGCAATCGCCGCGCTTTGCGAGCCCCTCGCCCAGCTCAGCCAGCTCATCGATGGTTGTGGCTGTGGCTGGTGCAACGACAACAACGCCACCCGACAAGCATCCCGACCAGAATGGTCAGCTAGCATTGACGCCACGCTCAGCGAGCACACCAACAACAACAACAACACCCACCATCAATACCCTCAACGCCACCAAGACACCAGACACGGAACGTGATTCCAATCTCGACGCAAGTTGCTACAATTGCGGCTACTGCGACAAAAAGTTTCGCTACGAGAACAATTTGATAATCCATCAGCGAACGCACACCGGCGAGAAGCCTTACAAGTGCACGGCCTGCGACTTTGAGTGCTCGCACATACAGAAGCTAATGAAGCATATGCGTGTGCATCGCAGTCCGGCGGACAATAATAATGGTGATGGTGGGGATAATCCCGATGGCCACGACGGTGGCAGCAATGCCGATTCGATTGAAACCAATGAGGCGGACAACGACGATGATCCCAATCCCGATGATTCCGACGATGAGCTAAACGACGAGGATGCCGATGCGGATGCAGATGCGGATGGCGAGGACGATGACGAGGATGAGCTGGACGATTGTGATGATGTGGACTATGAGGCAGAGGATTTGAGCGTCAACAATCGCATCGATGGCAAAAGTCAGAGCCCAAAGACGACCAGCTCGGGTGCCACATCGCTGGTGGGTGAGCTAATGGACAAGTTCGGCCTCTCGAACATTGCGCAATATTCCGAGGCATATAAGCAGGCGCTGCAAGAGTCCGGACGCAAGGAGGCTGCAGCTGTGGCGGCTGCCGCTGCTGCCGCCGCTGCCGTTGTCGACAACAATAATCATCGTGGCACACCAGTTCTGGGCTCGGCCAATCCGGCCGCCAATCCAGCCGCCCAGCCTATGGGCGATAAGCTCAATGGCCTCCCAGTTGCCGCGTTGCGTTTGCGCGATGAATTCGCCAAGAACTGCAATATGTTCCAGCCGCAGCCGCAGCAGCAGGATGCGCCGACGCAGGTGCCGCTTTTCAATCCCTTCCCCAATCCCTTTGAGCTGTCCAAGCGCATGAAGATCGACGGCGGCGATTGGTGGGGAATGTCCGCGCTGCATCGCAACGAGGCGCTCTTCGAGAACCTCAAGCTCAAACCGCTGGGCCTGGGCGGCGCCAATTCGCTGCTGCAGGGACCATTGCTCAAAAAGGAGAGCCGGCAGCGCAACGATACGTGCGAGTTCTGCGGCAAGGTCTTCAAGAATTGCTCCAATCTGACGGTGCATCGTCGCAGCCATACCGGCGAGAAGCCCTACAAGTGCGAACTTTGCTCCTATGCCTGCGCCCAGAGCTCCAAGCTGACGCGGCACATGAAGACGCACGGACGCACCGGCAAGGATGTGTATCGTTGCCGCTTCTGTGACATGCCCTTCAGCGTACCCTCCACCCTCGAGAAGCACATGCGCAAGTGTGTCGTCAATCAGGGCAAAGCCGCCGCAGCTGCTGCCAATGCCGCGAATGCTGTGGCCGCTGCCCAGGCTGCTGCCGCTGCCCAGCAACTTCAAGCAGCTGCTCAGGCCCAACAACAGCAACAGCAGCAGCAATCGATGCCATCATCGCAATCCCAGTTGTCGCCCGCCTGTTCGATGGGCGTGGCTGTTGGCTATCCGCCACAATTCGGACACAATCTGTCGCTGGCGGGCAGCGTGAGTGGCGATAACGATTCGAACGCATCCTCCAGCCTGCCAGCGCATTCCTCCATATCGCTCAAGGAGGAGGCATGA
Protein Sequence: MYNKVLSISEDHGFRSLSHSDSTENDAVAAQDILTCGACHKTFALSDIVRFIQHKVLQCNKENYGQCTTQAPSMDRDADEGRPLSLVNRRPSISAPITGRKSAPSLSTAGSGATVAAQSAAAAAASASANAAAATAAAAAAAAAAVASSAASGSRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKAESDALTNTATGGGATLETSNAHSPQDQRIGRSDECTLHDDKPKVKQEPYADDDDDNEDNDEQQHHLDEELQLDQDPEREERELLTQTNTDTECSQPLAKRPKMELVDAEANTVHTEPSNYTCSTCKTRYTSAWRLIQHVQHSHGVKIYVEAGGCAPPDSLHPNPFQLLRMPLPPALSQSNVVPSVSPLFGRPTPADHYRMEQLVSEQFRHHGFNLAAAAAAAQAQFNAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSPAGSLNLEPQQMDFYSQRLRQLAGTTSPGAGNIVNSSSPSPRQKQSPRFASPSPSSASSSMVVAVAGATTTTPPDKHPDQNGQLALTPRSASTPTTTTTPTINTLNATKTPDTERDSNLDASCYNCGYCDKKFRYENNLIIHQRTHTGEKPYKCTACDFECSHIQKLMKHMRVHRSPADNNNGDGGDNPDGHDGGSNADSIETNEADNDDDPNPDDSDDELNDEDADADADADGEDDDEDELDDCDDVDYEAEDLSVNNRIDGKSQSPKTTSSGATSLVGELMDKFGLSNIAQYSEAYKQALQESGRKEAAAVAAAAAAAAAVVDNNNHRGTPVLGSANPAANPAAQPMGDKLNGLPVAALRLRDEFAKNCNMFQPQPQQQDAPTQVPLFNPFPNPFELSKRMKIDGGDWWGMSALHRNEALFENLKLKPLGLGGANSLLQGPLLKKESRQRNDTCEFCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAAAANAANAVAAAQAAAAAQQLQAAAQAQQQQQQQQSMPSSQSQLSPACSMGVAVGYPPQFGHNLSLAGSVSGDNDSNASSSLPAHSSISLKEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -