Basic Information

Insect: Scaptomyza graminum
Gene Symbol: zfh1_3
Assembly: GCA_018901835.1
Location: JAEIFL010000277.1:11128766-11154273[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0043 0.28 11.5 1.0 2 23 87 109 86 109 0.92

2 9 0.0014 0.09 13.1 0.1 1 23 316 338 316 338 0.97

3 9 2.9e-05 0.0019 18.4 1.8 2 23 353 374 352 374 0.97

4 9 1e-05 0.00065 19.8 6.4 1 23 383 405 383 405 0.99

5 9 0.00029 0.019 15.2 1.2 3 21 413 431 411 432 0.94

6 9 0.027 1.7 9.0 0.4 2 21 669 688 668 689 0.92

7 9 2.3e-05 0.0015 18.7 0.5 1 23 1032 1054 1032 1054 0.94

8 9 4.9e-05 0.0032 17.6 7.4 1 23 1060 1082 1060 1082 0.98

9 9 0.0025 0.16 12.3 4.3 1 21 1088 1108 1088 1109 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0043	0.28	11.5	1.0	2	23	87	109	86	109	0.92
2	9	0.0014	0.09	13.1	0.1	1	23	316	338	316	338	0.97
3	9	2.9e-05	0.0019	18.4	1.8	2	23	353	374	352	374	0.97
4	9	1e-05	0.00065	19.8	6.4	1	23	383	405	383	405	0.99
5	9	0.00029	0.019	15.2	1.2	3	21	413	431	411	432	0.94
6	9	0.027	1.7	9.0	0.4	2	21	669	688	668	689	0.92
7	9	2.3e-05	0.0015	18.7	0.5	1	23	1032	1054	1032	1054	0.94
8	9	4.9e-05	0.0032	17.6	7.4	1	23	1060	1082	1060	1082	0.98
9	9	0.0025	0.16	12.3	4.3	1	21	1088	1108	1088	1109	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTTTGGCCAAGAGGATAACATTATAATACAGCAGAGTATGCCATCATCCGCCGCCTTCTCCATGCAGTTTTCCTCTTTGGCCTCAAGTTTGCATCATCATCAACAACAACAAGCGTCGGCGCATAATAGCAAGCCTTTGAGCAATGTTGTTGCTGGCAATTTGGAGCATGTGGCACATGCAACCAGTGCTGCCACAACCAATGCCACAATCGATAGCTGCATGATACAGTGCCCCGAGTGCCACAAACGCTTCAACGAGTTTCAGTCGTTCAGCGAGCATATTGCCCAGGAGCATCCGCATGACAAGTTGAACTATGAGCAGACGCATCGCGGGGCAGCCGTTGGGGCAGCTGATGCTGCAAGCGAAGCGGAGGAGGAGGAGGATGGGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAAATCAAAATAATCATCATACATCGGCTTCCCATTCGCCGCTCTGCTCGCCGGTTGCCCAAACAGCGGCCAACGATCTGTTTGCCCACCTGCCGCATCCCCCGCCTCAGCTGCCGCCCCATTTGCATGCCCAATTTATGGCAGCAGCCGCCTTGGCCATGCAATCGGCTCGCACCGCCAGCTCACCCAGCCACCACCAGCACCACCATAGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCCTACGATTTGGATTTAAGTGCTCATCGTTCCACCTCGAGTCCGGGCTCAACAACGGGTGATCTCAACACCGCCTTCCCCTGCATGCAATGCACCGCCGCCTTCCCCAGCCGCGAACAACTCGAACAGCATCAGCTGTTGCACTCGCCAACGGGCCAACATACAACAACACAAAATGTTACGCAGACATGCAAAATTTGCCACAAAGCATTCGCAAATGTTTATCGACTGCAACGCCATATGATTAGCCACGATGAGTCGGCGCTCCTTCGCAAATTCAAGTGCAATCAATGCGACAAAGCATTCAAGTTCAAGCACCATCTCAAGGAGCACGTCAGGATCCATTCCGGCGAGAAGCCCTTTGGCTGCGACAATTGTGGCAAGCGTTTCTCGCACTCCGGCAGCTTCTCCTCACACATGACCTCCAAGAAGTGCATCAGCATGGGCCTCAAACTCAACAACAATCGCCAAATGTTGAAAACTCTCGACAAGAATACGGATCCCCAACAGCAGCAGCAGTTGCCTCAGGGTAAACGCTCCTCCTGCAAACTGATGCCGGAACAGATTCTACCCAATCCGATGAACTATTTCGCTGGCGATGCTCAGGCGCCCGTTGGAGGAGTCGGATCAGTTGGGGCTGGTGTTGGAGGCGTTGGTCCTCCTCCGCCGCCATTCTATTCCAATTATAGTGCCATGAATGCGGCGCTGTTGGCATTTCCCAATGCCTTTATGGCCGCTGCACTCGATCCTCGCATGCATCCCTATAGCATACAGCGACTCCTCGAGCTAACAGCTGCTGGCCAGCAGCAGCAGCAACACCAGCAGCAGCAGCAGCGGGAAGAAGAGCAACGGGAGCAAGAGGAGCTCCAGCAACCCCCCAAGGATGTTGAGGATGAGACACCAGATGAGCCCAAGCTGGTCATGGATCTGGAATCGGAGGCGGAGCTGATGAAGCCGGCAGCTACGCCCCAGCAGAGTCCTGCCGCTGTCAAGCTGGAGCCCAGTCGGGAGGCAACCCCCCTGCTGGCCGAGGAGCACCCATCAACCCCCAAATCGATTAAGCAAGAGCAGGAGCAAGTGGAGGAGCATGTGGAGGAGCGGGAGGAAGAAACTAACCAAGAGACGGCGGATCTGCGCTGCAGTCGCTGTGCCAAGCAATTCAATCATCCCACAGAGCTGGTGCAGCACGAGAAGGTGCTCTGCGGATTGATCAAGGAGGAACTCGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACGAGCTTTGTCCTGCCCTCGGCCAGTGAGGCAGATGAGGAGGACGACGAGGAGGAGGAGGAGGTGGGCGGAGAGGAACCACGTCAGGATTACCATGCCGGCAGCAGCGATAGCGGGGAGCGCAAAGTGCGCGTTCGCACCGCCATCAACGAGGAGCAACAGCAACAGCTGAAGCAACATTATGCCCACAATGCCCGGCCGAGTCGGGACGAGTTCCGTCGGATTGCCGCCCATCTGCAGCTGGACGCGCGCGTGGTCCAGGTCTGGTTTCAGAACAATCGTTCGAGGGAGCGCAAACTCCAGAGCTTTGAGGCGGCGGCGACTGTCGCCATTCCTTCGACAAATGCTGCACTGCCTCCGCCGCCGCCGCCGTCGACTGGAATACGTGCTGCTGGCGAGGATCAGCCATTGGACTTGTCGGTCAAACGGGACGCAACACCGCCGCTGCAGCAGCAACAGCCGATGCAGCTGCCCAACGACTATCCCGAAGCTATGGCCATTAATCTGAGTCGCAAGTTGTCCAGCTCCGCGTCCATGTCGCCAGCCTCGCTGTCGCCGGCAGCAGCGGCTCTTTACTTTGCGCCACCCTCGCCGCCCAACATGCACGAGGTGACAGCGCCTTCGATGCCGCCCCGATCGGCACCCTTTCCCGGCCTGCCGCCCTTTCCGCTGATGGCTCGCCTGCCGATGGAGGCGCTCTTCCAGATGCGTCCCGGCGGCGATTACGCGCCCAATCCTCTGATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGCCTCAGTCCCGGCGGCTCCGAGAAACGCTCGTGGCGCGACGACGATTCCCGCATCTCCCACGAGGATGATTATGTTTTGGCGAGCTCGGGACTTTTGCCACCGAAACCCAAGCGTGCCAAGGCCGAGACCCATGGCCATGCCGGCGATCCCGATCTGCCCTTCATCTGTGACCAATGCGACAAAGCCTTTGCCAAACAGAGTTCCCTGGCCAGGCACAAGTACGAGCATTCCGGTCAACGACCGTACCAGTGCATGGATTGCCCCAAGGCCTTCAAGCACAAACACCATTTGACGGAGCACAAACGTTTGCATTCCGGCGAGAAGCCATTTCAGTGCTCCAAGTGCCTGAAGCGATTCTCGCACTCCGGCAGCTACAGCCAGCACATGAACCACCGTTACTCGTACTGCAAGCCGTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRFGQEDNIIIQQSMPSSAAFSMQFSSLASSLHHHQQQQASAHNSKPLSNVVAGNLEHVAHATSAATTNATIDSCMIQCPECHKRFNEFQSFSEHIAQEHPHDKLNYEQTHRGAAVGAADAASEAEEEEDGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNQNNHHTSASHSPLCSPVAQTAANDLFAHLPHPPPQLPPHLHAQFMAAAALAMQSARTASSPSHHQHHHSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAYDLDLSAHRSTSSPGSTTGDLNTAFPCMQCTAAFPSREQLEQHQLLHSPTGQHTTTQNVTQTCKICHKAFANVYRLQRHMISHDESALLRKFKCNQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRQMLKTLDKNTDPQQQQQLPQGKRSSCKLMPEQILPNPMNYFAGDAQAPVGGVGSVGAGVGGVGPPPPPFYSNYSAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQQQHQQQQQREEEQREQEELQQPPKDVEDETPDEPKLVMDLESEAELMKPAATPQQSPAAVKLEPSREATPLLAEEHPSTPKSIKQEQEQVEEHVEEREEETNQETADLRCSRCAKQFNHPTELVQHEKVLCGLIKEELEXXXXXXXXXXXXXXXXXXXTSFVLPSASEADEEDDEEEEEVGGEEPRQDYHAGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRRIAAHLQLDARVVQVWFQNNRSRERKLQSFEAAATVAIPSTNAALPPPPPPSTGIRAAGEDQPLDLSVKRDATPPLQQQQPMQLPNDYPEAMAINLSRKLSSSASMSPASLSPAAAALYFAPPSPPNMHEVTAPSMPPRSAPFPGLPPFPLMARLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHEDDYVLASSGLLPPKPKRAKAETHGHAGDPDLPFICDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01321430;
90% Identity: iTF_01322542;
80% Identity: iTF_01322542;