Basic Information

Gene Symbol
-
Assembly
GCA_018901835.1
Location
JAEIFL010000243.1:13937981-13940485[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.011 0.74 10.2 3.7 3 23 276 296 274 296 0.97
2 12 0.0099 0.64 10.4 0.4 1 23 302 327 302 327 0.91
3 12 0.0019 0.12 12.7 1.0 1 23 334 359 334 359 0.96
4 12 0.00049 0.032 14.5 2.6 1 23 371 393 371 393 0.97
5 12 1.8e-06 0.00012 22.2 0.1 1 23 400 422 400 422 0.98
6 12 0.011 0.73 10.2 0.2 1 23 428 450 428 450 0.97
7 12 0.06 3.9 7.9 3.0 1 23 456 479 456 479 0.97
8 12 0.0046 0.3 11.4 4.6 1 23 485 507 485 507 0.97
9 12 0.095 6.2 7.3 5.3 2 23 514 535 513 535 0.96
10 12 0.00011 0.0069 16.6 0.2 1 23 636 659 636 659 0.95
11 12 0.091 5.9 7.3 1.3 1 21 665 684 665 687 0.75
12 12 1.5e-07 9.4e-06 25.6 3.0 1 23 693 715 693 715 0.98

Sequence Information

Coding Sequence
ATGGACGTGGCGCGGACATACTCCATACATACGCTGTGTCGCATTTGTTTGAATCTCCTGCAAAACGATGCTGCCTACGACCTGTATTTGGTGCCTGGCCTGGCTAAAAAACTTTGCCTCTGCACCTCGCTGTCTGTGGAGCAAAATGATGGCTTTCCCAAAAACCTGTGTACCAATTGTTATACCCGGCTCAACGATATGCATGATTTTCAAAAACTATGCGTCGACTCTGTACAAAAGTTTCAGGACATGGTCTCGAGCAACGCCTTTACATGCCAATCGAACTTTGACGTACTGGATCCAAGTGTGTCAGCGCACGATCTGCCCAACGATGATGAGGACCACATTAATTTTGACCCATTGCTGAATCACAAAATGGAGCTAATCGAGAACGAAGAAGATGTTTTCAAGATGCTTGAGGACTGCGATAAAGAAGCCGAGGAGGTGGAAAAGAAAGAAAAAAAGGAGATCAATGAGCCAATTATAGTGAACATGTTCAACGAAGACTCATCTTCTATTGAGAGCGGCAATGACAACGACAGGGACATGGACTTTGAGCCAAACAGCAGCGACGACGACATTCCTTTGGCTCAACGCATCCGAGGCAAGAACACCAGAGGCGTCAAGTCCAAGCCCAGAAAGAAGAAGACTGCTGCTGCCGGCGGCTTTGACAACGACGACGACGATTTCACTACTTCATCGGATGACGACTCTTACGACGATGACGACGACGAGGCCGATCCCGACCGTAGACGGCGCTCTAGAGACAAACCAAAACGCAAACGCATTCCTGCTGCCGAGCGACACCTGCATCGTATCATCGACTGCCACATTTGTCACCAGAAATTTAAGAAGGCTATCCGCTACGAGGAACACATGAAGTATCACAACGATTTGTTGCCCTTCCAGTGCAAGGTAGAGGCCTGCAAGAAAGGCTTCACTACCGCCAATGGACTGCGCATCCACGTCGATCACGCTCACACCGAACTATCTGAGGTGCATACCTGCAGCGCTGAAGGCTGCGGTAAGACATTCCCACGTGTGCGTCTGCTTACCTTCCACATGAAGAAGGTGCACAACATTTCCAAGTCGGCGGCCCCGCTGCGCGACTTCCCCTGCACCGAGTGCAACACAGTGTTCCGTTGTCCGACAGCGCTCAAGAAGCACATGTATAAGCACACCGGCGAGGAGCTGCCATATCCATGCAACATATGCGGTAAACGCTTTGTCATCAACAGCGCACTCAGGGATCATCTGATGCGGCACGCTGGCATCAAAAACCACGTTTGCCCTTACTGCGGCGTAGGTAAAACTACTCGGCAGGAGTGGAACGCCCATATCCTTACGCACACCAAGGAAAAGAAGTTCAAGTGCCGCCAGTGCGATCATGCTTCCCACAACAAACAGGCTCTGTCCAATCACGTCAAGGTGGTGCACATGAAAATCAAGAACTTTGCCTGCCAGTATTGCGGCAAGACCTTTGGCAAATCGCATGCCTGCAAGGTGCACGAGAGGACGCACACGGGCGAGAAATGCTGCGAGTGCAAGATCTGTGGCAAGATTTTCCTTTGCGAAAAGAGCTTAACTAAGCATTTAAAGACGCATGAGAAGCGCGATTTGCCGCCAGTAGACCATCGACCGCTCAACATTCCGCTTCCCGGACTTCAAATACCTCCGCATTTGCAGGACGATGGCATGATGCCTCCAAATATGGCTGACGATTTGCTTAAAGCGTGTGGCGGCGGGCCCGCAACAGCAGCAACGGCAGCGGCTAAGCCGAAAAATTCACGACGCGTCCAGCGTGTGGATATCTCGCAACTGGCGGGCACCTCAGTTAATCCCATACCATCAGTATCGGTGCCATCCTGGTCACCTCAAGTCAACTTCACAAAGAAAGAGGGCCAACACATTTGTCCAGGATGTGGGCGGGGCTTCAACAATATTGGCAACATGAAACTTCACTACAAGATCATTCATGAAAAGGTAAAGGACTTTGCCTGCCGTTTCTGTCCCAAGCGTTTTTCGAAAGCACAAATCTTGCGGCATCACGAATGGATACACACCGGCGAGAAGCCATTCGAGTGCAAGATTTGCGGCAAACATTTCCGTCAGGAAACGGCGCTTAAAAAGCACATTAAGACGCACGACAAGCCCAACAGGCGCCACTATCCGGAGAAGGTTCAAGAACCGATAATCACGTTCCACAAGATCGAGCCGCGGGAGATTGATCGCGAGCCACGAAACTACGATCAGTATCAGGATCCGGCCGCAGAGCGAGCTGCCGCCACTGCTGAGCTGCTTGCCCATCAGATTGAGGAGAATGAGGCAAAACGCAAAGCCGACATTGAACGAAGAAAGATTCAGGAAGCTGCTTGCGAGCAGCTTAACAAGCTGCAGCAGCAGCAAGAGATCGAGAAAGCGACCACTTCCTATGACGGCTACTTTCAACAAAAGGCTCAAGCCGAAGGCATCAGTGTGGATGCGCTCAAAATTGATCATGTTTAG
Protein Sequence
MDVARTYSIHTLCRICLNLLQNDAAYDLYLVPGLAKKLCLCTSLSVEQNDGFPKNLCTNCYTRLNDMHDFQKLCVDSVQKFQDMVSSNAFTCQSNFDVLDPSVSAHDLPNDDEDHINFDPLLNHKMELIENEEDVFKMLEDCDKEAEEVEKKEKKEINEPIIVNMFNEDSSSIESGNDNDRDMDFEPNSSDDDIPLAQRIRGKNTRGVKSKPRKKKTAAAGGFDNDDDDFTTSSDDDSYDDDDDEADPDRRRRSRDKPKRKRIPAAERHLHRIIDCHICHQKFKKAIRYEEHMKYHNDLLPFQCKVEACKKGFTTANGLRIHVDHAHTELSEVHTCSAEGCGKTFPRVRLLTFHMKKVHNISKSAAPLRDFPCTECNTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALRDHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVKVVHMKIKNFACQYCGKTFGKSHACKVHERTHTGEKCCECKICGKIFLCEKSLTKHLKTHEKRDLPPVDHRPLNIPLPGLQIPPHLQDDGMMPPNMADDLLKACGGGPATAATAAAKPKNSRRVQRVDISQLAGTSVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFNNIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKICGKHFRQETALKKHIKTHDKPNRRHYPEKVQEPIITFHKIEPREIDREPRNYDQYQDPAAERAAATAELLAHQIEENEAKRKADIERRKIQEAACEQLNKLQQQQEIEKATTSYDGYFQQKAQAEGISVDALKIDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01570408;
90% Identity
iTF_01323568;
80% Identity
-