Basic Information

Insect: Scaptodrosophila lebanonensis
Gene Symbol: ush
Assembly: GCA_003285725.2
Location: NW:4384971-4492741[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0057 0.36 11.0 0.0 1 20 235 254 235 256 0.90

2 9 0.00025 0.015 15.3 0.8 1 23 308 330 308 330 0.98

3 9 0.041 2.6 8.3 1.0 2 21 368 387 368 388 0.92

4 9 0.043 2.7 8.2 2.9 2 21 783 802 782 803 0.93

5 9 0.0079 0.49 10.5 0.0 3 21 844 862 842 863 0.91

6 9 0.088 5.5 7.3 0.0 2 23 952 973 951 973 0.97

7 9 0.0031 0.19 11.9 1.5 1 23 979 1001 979 1001 0.99

8 9 0.00034 0.021 14.9 1.2 1 23 1062 1085 1062 1085 0.96

9 9 0.27 17 5.7 0.7 2 20 1193 1211 1192 1213 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0057	0.36	11.0	0.0	1	20	235	254	235	256	0.90
2	9	0.00025	0.015	15.3	0.8	1	23	308	330	308	330	0.98
3	9	0.041	2.6	8.3	1.0	2	21	368	387	368	388	0.92
4	9	0.043	2.7	8.2	2.9	2	21	783	802	782	803	0.93
5	9	0.0079	0.49	10.5	0.0	3	21	844	862	842	863	0.91
6	9	0.088	5.5	7.3	0.0	2	23	952	973	951	973	0.97
7	9	0.0031	0.19	11.9	1.5	1	23	979	1001	979	1001	0.99
8	9	0.00034	0.021	14.9	1.2	1	23	1062	1085	1062	1085	0.96
9	9	0.27	17	5.7	0.7	2	20	1193	1211	1192	1213	0.91

Sequence Information

Coding Sequence: ATGTCACGACGCAAACAGTCGAATCCAAAGCCGTTGAATAAAGgtGATTGTTCCGATACCACAGAAGAGATGACCGTTGACAGCAGAGATTCCAAAGATATGGGCGAGGAGAAACAGCTGTTGGAGCCCAATGAAGAGCACAGCCAAACGAATGCTACTGAGCAGGAAGATGATGAGACTGAATGCGGCTTCGCTGCAGGTGATAATGAGAACGCTGCGATGAGAGAGACCCCGCCACCGCCGGCCAAATCAAGTCCCCATTTGGAGGCCAAGCTGGAGCAGCATCAGCCGGAAGCGCTACCCTCGCGTCCCACCAGCAATGAGGCACGCAGCCCAACGCCTGCACGCTCCGAGCAGCGTCTGAACAGCTGTGATGAGCTCATACCGAAGCTGGAACTGGATATGGACACGCCATCGCCTTCCTCCACAACACGACCCACTACAGTATCCCCGAGCCCCTCACCACCGCAGAACGAGCGCACGCCGCTGCCTCCTTTGCCAAAACTGCGTCTCAACACGCTGCTTGCCTCAGACCCAGCTCTCAAGCCCGATGCCAAGGAGTTGAGCCTAATGCACGAGGAGACACCCTCGAAGCAACGCTTGCTGGCCGCCACAGCATCCGCGCTTAGCAAgcaacagcaggagcagcagcagcagcagctggcCGATGCTTTGGTCGAGCCTTTGCTAAAGCCTGCCCGCTTCATGTGCCTGCCCTGCGGCATTGCCTTCAGCTCACCGTCAACGCTGGAGGCACATCAGGCCTACTACTGTTCACATCGCAATAAGGACGACGATGAGGTGCTGCCTGTGGCCGACAAAGCCTCAGGAACGGCCTCTGGCGCATCTTCGGCTTCCGGAGGCGGCACTTCCGGAGGCAGCTCTGAGCCAGCAGCCAAGGCTGCGCGAACGGGCAAGCAATACGCATGCACTCAATGTTCCTATAGTGCCGACAAGAAGGTCTCGCTGAATCGTCACATGCGCATGCATCAAAGCTCCCCGGCTCCCAGTCTGGGGGCATGCAGCGCCAATGGCGCGTCTGTGGTGCCAGCCCCAAGCGGCGCCGGATATGAGGAGAGCTCTAGTCAACAAACCGACCGTTACTGCAGCGATTGTGATATACGTTTCAACAATGTGAAGACCTACCGCGCCCACAAGCAACACTACTGCAGCTCACGTCGCACCGAAGGCTCCATGACACCCAAGCTGGAGACCAGTGGGGGCACTGCGACTGCGGGCGTCAACAAGGCCGCCTTGGTCAGTGGCGCCCACAGTCCCCAGACGCGCAATAAGACCCCCACACCGGCCATGgtggctgcagcagcagctgccgcgGCTGCGGCCGCTGCCTCACTCCAAGTGCCGCCTCCTCAACCGTTCCTGGCGCTGCCCACAAACCCCATCATCATTGTGCCCTGCTCGCTGATACGAGCGGCCAGTCTTATTCCAGGACCACTCACCACTTCGACCTCGGGCATTGTGAATCCCGAGTCCACATGCTTTGCACTCGAGAATGGGGCCCTGAAGCCGCTGGCCACGGCTCTCAACATCAATGCGTTGACCAGCAATCCGGCAAATGCTGTGCCCAACAACAACCCACCAGCGATGCCGAACTTGGAGCCGGAACGTAAGCCAACCAGCGCTGCGGTGGAGCCAGAGAAGAGCAATGCCATTGAAAATGTGCCCGTGAAACGCAAAGAAGCCGGCGGCACACGCGAATCGACGCCGCTGGATCTCTCTCTACGTAGGTCGCCCATTTCGGTGCAACGTCAGCGTCTCATACGCTCCGCCACCGCACTTCTGGACACTGAAACTCAACAGTCGCATCGCATGGATATGGAGTCGCTACTGGAGGCGAGCAAAGAGAATCTGGCGCTAGACCAGAGCGGGAGCGTGACCCCCGAGCAGATCGTATGCGCACCCTCCCTGCCCAGCAGCCCTTCAATGAGTCCCTCGCCGAAGCGACGAGCCATCAGTCCGCGCAGCTCAGGGGCCGGCAGCACATCCTCGATGTCGCCACCAACGAGTGTGAGCGTGCCACATTTTTCAGCAGCAGCCACCGCCGCTGCTGGTCTATTGGACAACTTGCCACTGCGCTCCATGCTGCCCGCTGATTTTGCTCTATCGCTCTCGAATTCCGAATCCTTGTTGGCGAAGACAAATCCTGAGCTCGCACTGAagttggcagcagcagcagccgctgctgTGGCGGGTAGCACCACAGCAGAGTTGGCCAGCAAGCTGGGCTTTTCGGTGCCACCTCCAGCTGCGCCGACCACGGCTCCAACAGCCGCTCCAAACACGCCCAGCGGCCAGCCTCAGATCTATGTGAAGCAGGGCGTATCCAAGTGCAAGGAATGCAACATTGTCTTCTGCAAGTATGAGAACTATTTGGCCCACAAGCAACACTACTGCTCGGCACGCAATCAGGAAGGCAACGAGGGGGAATCCAAGCTCACCCGAACATCCCCAAATACGAGCATCGGCTCGTCAGCGGACTCCACGCCCGTGGCCTATCAACAACTGATATGTGCGGCCTGTGGCATTAAATACACCTCGCTGGACAATCTGCGAGCTCACCAGAACTACTATTGCCCCAAGGGAGGCGGCGCCCCAGCAGCTGCCACTGGAACAGGAGCAACAGCTATGGATACCGTTTCGCTCAGCCTACCCAAGGAGAAGTGCGGCAAGTGCAAAACAGTCCATGAACATGGCCTGCCCTGTCCCCCACCAGCAACGTTGCCACAACCCCAAGCTTCACCACTGATTGCGCCAAGTGCTGGAGTAGAGCGCGTCATCAGCACCACACCAGCCCCTTCGACAACATCGTCGTCCTCGTCGAACAATGTCAACAAGTGTCCTGTGTGTGGTGTGCTTAGCCCTACGGCAGCGCTGGCCCGCAAACACATGGAAATGCACGGAACTGTGAAGGCTTTTCGCTGCACCATCTGCCAGTACAAGGGCAACACGCTACGCGGCATGCGCACCCACATCCGAACACACTTTGACAAGAAGACGAACGACATCAATGAGGAGCACTACATGACGTGCATTTTCGAGGAGGACTCACTCGAGGTGCccacagcagcggcagcaatgCAACAGGAACAATTGGAGCAGCAGTTGCAGGCAGCAgccgcagcggcagcagctgccgcCATCGCGGAGCAGACGCCCCAAATCTTTAATTGCGATTATTGCAATTATACTTCCACCTACAAAGGCAATGTGCTACGGCACATGAAGCTGGTGCATCCACATGCAGCCATCAGCTCGCCTTCAATATCTCCCGAGTCGCGGGAGCATGAGCCCGCTACGGACGTTACGGCTGTAAACGGCGAAGCAGCCAACTTTCATATTAAATCGGAGCCGCTGGATCATCCCACTGGCGTAGTTTCTAATCTGGGTCTTGTGCATGAGAACAACAATTCTCCACTAGCCACGCCTCTGCCGCACATTAAGGCCGAGCCTATGGACATAGGTCTCGATGTGGTTCAACCGCCGCCACTTCCACCCAACCTGCCGCCGCCTGTTGCCTCGCCGCTGGGCCCCACCGCCGCCGAGGCCATGAAGAAGTACTGCTCCACCTGCGATATATCCTTTAACTATGTGAAGACCTTTCTGGCCCACAAGCAATTCTACTGCAAGAGCAAGCTGCAACGACCCGAGGCGAACGATAGTCCCAGTCCCAATCATGTGGGCGTAGCAGGACATGCCATGCAGCCGCTACAATCCCCCAGCGAGTTGCTCTTGCTGCAGAAGAATAAGGAGAATCTACAGGAGGCGGCCATTTGA
Protein Sequence: MSRRKQSNPKPLNKGDCSDTTEEMTVDSRDSKDMGEEKQLLEPNEEHSQTNATEQEDDETECGFAAGDNENAAMRETPPPPAKSSPHLEAKLEQHQPEALPSRPTSNEARSPTPARSEQRLNSCDELIPKLELDMDTPSPSSTTRPTTVSPSPSPPQNERTPLPPLPKLRLNTLLASDPALKPDAKELSLMHEETPSKQRLLAATASALSKQQQEQQQQQLADALVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDDDEVLPVADKASGTASGASSASGGGTSGGSSEPAAKAARTGKQYACTQCSYSADKKVSLNRHMRMHQSSPAPSLGACSANGASVVPAPSGAGYEESSSQQTDRYCSDCDIRFNNVKTYRAHKQHYCSSRRTEGSMTPKLETSGGTATAGVNKAALVSGAHSPQTRNKTPTPAMVAAAAAAAAAAAASLQVPPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFALENGALKPLATALNINALTSNPANAVPNNNPPAMPNLEPERKPTSAAVEPEKSNAIENVPVKRKEAGGTRESTPLDLSLRRSPISVQRQRLIRSATALLDTETQQSHRMDMESLLEASKENLALDQSGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSTSSMSPPTSVSVPHFSAAATAAAGLLDNLPLRSMLPADFALSLSNSESLLAKTNPELALKLAAAAAAAVAGSTTAELASKLGFSVPPPAAPTTAPTAAPNTPSGQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEGNEGESKLTRTSPNTSIGSSADSTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGGAPAAATGTGATAMDTVSLSLPKEKCGKCKTVHEHGLPCPPPATLPQPQASPLIAPSAGVERVISTTPAPSTTSSSSSNNVNKCPVCGVLSPTAALARKHMEMHGTVKAFRCTICQYKGNTLRGMRTHIRTHFDKKTNDINEEHYMTCIFEEDSLEVPTAAAAMQQEQLEQQLQAAAAAAAAAAIAEQTPQIFNCDYCNYTSTYKGNVLRHMKLVHPHAAISSPSISPESREHEPATDVTAVNGEAANFHIKSEPLDHPTGVVSNLGLVHENNNSPLATPLPHIKAEPMDIGLDVVQPPPLPPNLPPPVASPLGPTAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLQRPEANDSPSPNHVGVAGHAMQPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -