Sleb010131.1
Basic Information
- Gene Symbol
- RREB1
- Assembly
- GCA_003285725.2
- Location
- NW:3728967-3739951[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0087 0.54 10.4 0.8 1 21 233 253 233 255 0.93 2 13 0.00028 0.018 15.1 0.2 1 23 265 287 265 287 0.98 3 13 2e-05 0.0012 18.7 7.5 1 23 293 315 293 315 0.98 4 13 5.7 3.5e+02 1.6 0.0 1 23 537 561 537 561 0.88 5 13 0.069 4.3 7.6 3.0 2 19 567 584 567 588 0.91 6 13 0.0075 0.46 10.6 0.1 1 23 754 776 754 776 0.97 7 13 1e-05 0.00063 19.7 0.7 1 23 786 808 786 808 0.99 8 13 0.0007 0.044 13.9 2.0 1 23 814 837 814 837 0.97 9 13 0.0026 0.16 12.1 2.1 1 23 1153 1176 1153 1176 0.95 10 13 7.3e-05 0.0045 17.0 0.3 2 23 1553 1574 1552 1574 0.97 11 13 0.12 7.6 6.8 6.3 1 23 1580 1603 1580 1603 0.97 12 13 0.0071 0.44 10.7 0.5 3 23 1803 1823 1801 1823 0.96 13 13 0.0065 0.41 10.8 4.9 1 23 1829 1851 1829 1851 0.99
Sequence Information
- Coding Sequence
- ATGCTTGCGACACAAaagacaacgacaacaacaggcAGCACACGCGAAGATGAGACCAACATCGAGCGCCAGCGTCGCGAATCGACCACCTCAGAGTCCTCGCTGGAGCACCTAGACTTGGGCCGCACTCCGAAAAAgctcagcagcagcggcggtgCACCGCAGCCGACCTCAACGCCACACAACCTCACGAATGGTAACGGCAGTGCCGGCAGCGAGCAGTCACGCAAGCGCAAGCTGCGTCATCAGCAGCTTCAAGACGAGCAGCCACAGGAGCCGCTCTCCGATGAGGAGGAGCATGAGGCTGTGTTGTCGCACAGCGACGAGACCTCACAGCGACTGCGCCACAAGCAGCGTCGGAGCAGCGGGCGTACAGCCACGGCCAGCATCGTGGCAGACTACAGTGGTGGCGATGCGAGCTCGTTGCGCAAAAAGTTCAGACTAAACCGCAGCAATGCCACTCCGGCCGGCGAGCTGTCCGAGTCAGGCTTTGTGGACGCCAGCGGCCATAGCGGCTACTTGCTGAATGCCTCGTCCGCTTCATCTGGCCCGGTGAAGCCGCCAGTGGTGACTCCCAGCGCTGGTAGCAGTCACAgtaatagcagcagcagcagtggcggcGGCTCAGGCGCTTCATCGCCTCATGGTCTCTCCAGCGCCGAGTCTGGCATTGGAGCTGTCGATGAGCACATGAAGTACTTGTGCCCTATTTGCGACGTAGTGTCAGCCACGCCACATGAGTTTACAAATCATATTCGCTGCCACAATTACGCCTCCGGTGATACGGAGAACTTCACGTGCCGCATTTGCTCAAAGGTTCTATCGTCTGCCTCTTCGCTGGACCGGCATGTGCTGGTACATACTGGCGAGCGGCCCTTCAACTGCAAGTACTGCCACCTAACCTTCACCACCAACGGCAACATGCATCGCCACATGCGCACGCAcaagcagcatcagcagcagccagCGGCGACGACGACAGCGACCCAAGGGCAGCGACGTCATTCGCATGGCGCCAAAAATGGTTCCGGGGCGGCGGGTGCCAATGCGGGTGCCCAGCGCCTCAATGGGGGCGGCGAAAGCTATGAGAGTGATGGCAGTTGCTCCACGGATGTCTCCAGTACCAATAGCCAAAgctcaaagcagcaacagcagctgcacaacaacaacaataataacaacaacactaacaataacaacgacagCCATaaaacgaacaacaacaacaacaacagcagcagcaacattgcTGGCAATTTAAAGCGTCAGCAGGGCGTCGACGCAGCCGCCATGTCTAAGCAGCGACGCGTGAAGACcacaatcaacaacaacataatcgacgcggatgtggatgtggacgttcacgccgacgccgacgctgatgccgatgccgatgctgacgatgatgacgGTGGCGCTAACTCCGATGTGGACGGTGATATTGAAGCTGACGGCGATGGTACCCCCGCTACTAGCGTTACAACGCCCCTCTCTTCGCCAGCTCACGTGGCCATTACCAGCACCCCTGACGTGGCCACCTTGCTGGCCGGTGCTTCTACCTCTCCAACACACTCTTCGGCCGAGGCGTCGTTGAGTATGGGACTGGGATTCAGCTGCCCGGCCTGTGGTGCCGCTGACTTTGATAACCTGCCCGCGCTTTGTACGCATATGGATGCGGCGCATGCGGATATATCTGCCAAATGTCGCGAATGTGACGTGGTGTTCCGCAGTCATCGCCAACTGATGGCACATCCCTGCAGCCACCGAGGATTGCCAGGGACAGGGACAGAGTCGGAGCTGCCCCCTTTATTGGGTGCCAGTTCGTCGCCATTGCATGAGGCGAACGACGATGGTGAGAGGGAGGATAATGTAGATGCTGATAGAGTTGGGGAGGTCGACGATGAGGAGTTGGCAGCGGCAGAACAGCGAGTAGACTTCTTTCGTCAACTCTACCTCAAGAACAAGGCAGCTGTTGCAGGCGAAAGTGCGGCCATGTTGTCACCAATCTATGGAGCCACGGCTACGACTGGAGCTTGCGGCAGCGGTGGCGAGATAAAGTACGAGCCAGATGGCAAGGAGCTGGCCGACATACAGTCTATACTGAACATGACCAGCTCGTCATCCACCTCCAATTTTCTGCGCAACTTCGAGCAGACAGTCAACACGCCCTCCAGCCAATACAGCTTGGATGGCAAGGATGAGGAGGAGGCCCAGGACGCTTTCACATCGGAATTTCGCAAGATGAAGCTGCGCGGTGAGTTCCCCTGCAAACTCTGCAGTGCCGTCTTCCCCAATCTGCGCGCCTTAAAGGGACACAATCGTGTTCATCTCAGCGCTGTGGGTCCGGCCGGTCCTTTCCGCTGCAACATGTGTCCCTATGCAGTTTGCGACAAGGGGGCCTTGGTACGACACATGCGCACCCACAACGGCGACCGTCCTTACGAATGTGCCGTCTGCAACTACGCCTTTACCACCAAGGCCAACTGCGAACGTCATCTGCGCAACAGACATGGCAAGACGACGCGCGAAGAAGTTAAGCGTGCCATTGTGTACCATCCCGCTGAGGACGCTTCCTGCGACGAGGCAACCTCCACAACCTCCAAGAATGCGTCGCGCATGCAGCAGCTCTATGGAGATGCGGGCGATCTTGATTTAGCCGACCTTAGCTTCCGCTCAGTCACGCCCACATCAGCGCCAGCTTCTGTAGAACAGCATGCCACGCCCGTCTCGCAACTGAAGCACATGCTGCTTGCCGAAGGACAGCCACCAGCCAAGATCCAGGTGAAGAGTTTGGACCAGCTGGTGGACAAgtcgcaacagcagcagcagcaacaacagtcaGAAACAAAACCAGCTACGCCTGCCACCAGCACCACACCAATGGACCTCAGCATGGATGTATTAGACCTTAGCAAGAAGCCCACGGCCCCCGTCCCCACGGTGGCCCCAGTGGACGAGCTGGCAGCCGCCctagagcagcaacaacagcagcaactgctgTTATCCCAACACCCTCTTATGTGCGCCGGCGATCCAACACAATACATGCAGCAGATCTTTCGTAACTTGATGTTTCAGCAGCCCTCGCCGTTTGCTTTCTTCAATTTCATGCCGCCCGCCAATTCGGCCAATCTCGCGGAGTCGCTGTTAAAGCGCATGTTTAGCAGTGCCGCAGGCAATAGCACGATCCCACCAACTCCGTCATCTGGCGGTGGGAATGGCCCAGATAAGCTAACCCCATCGGCTCTATTGCCGCAGATAAGTCCGCTTATGGCCGGGGCAGAGAAGCCAGTGTCGTCGCTGTTGCCACCCCAACACCCACATCCGCACGCACATCCACATCAACATCCTCATGCCGCCGGGGTGCCGCTGCCTGTTGGTCCTGTAAAGATGGTCATCAAAAATGGCGTGCTCATGCcgaagcagaagcagcgccGGTACCGCACAGAGCGCCCCTTCGCCTGCGACCACTGCTCGGCTCGATTCACTCTACGGTCCAATATGGAACGGCACGTGAAGCAGCAGCATCCGCAGTTCTATGCCCAGCGCCAACGTAGTGGCCACCACGTTATGCGTGGTCGAGGAGCCGCTGCAGCTGCCGCCGCCATGAATAGCATCAGCCATCTAAGCTTCGCGGCTGGTCAACAACAATCAGCAGCGCATCATAGCCATCATCAGGGCGTTCCTGGAAGTACTGGAGGCACCACACACATCTCCGTTCAAGTGAAGCATGCCATACTGGCGCAGCAGCTCAAGGCGCGCAAGGATACGGATCTGTTGCAGCAGGCCCTGGCACATGGTTCCAGCAGTGTGGCTGCGAATCCGTTGCTTCACTTCGGCTATGGCCACTTAAATGGCGCCATCCAACATTGCAACACAAATGGCAGTAGTAGCAGCCACAGCGCCTCAAGTACCAACCACAATGTCTCTAACAACAACGGCGTCATAGACGATGATGAGGACAAGTTGGTAATTGATGAGGACGATGTGGAGGAAGAGGATGAGGAAGAGATGGAAGAGGAAGTCGATGAAATGGATGATGACGACGCCGAAGAGCAACAGATGCATGCGGAGCCAGCAACAGGCACTGCTGCAGACGACTCGGAGGACATTAAGATCTTGCCCAAGCCGCTGGAACAGCTGACCAAGGTGCGAACACCATCGCCCATGGCGCCCAAAAGTCCACCCGAATCCAATGAAGCGGCTAAGAAGATGGCCGACAGCATACTCGAACTGGCTATAAAGAAGGCCGCAAAACCAACTACCGTCGCTGTCCCCGCCACAGATTCGGCCACATCGCTAGCAAGCCGGCCAACACCCACACCACCACCTGCACACACCATGAAGACAATGATTGCTCAAGTCGAGTCGGTGGCCAAGTCGCTCAAAGAGGTTGCCAGTTCACCATTCAAAGACGAATCTCAGGATCTGGTACCCGTATCGAAGCTCGTCGACAATGCAAACGCTGCCAGTGCCTCGTTCAACACCTATTTCCGACCCAGTGACGTGGCCAACCACATGGAGCAGAGTGATGAGGAGGGTCTTGTCGCCTCTGGCAGCGCCAGCGAAAGCAACAACTCTGGCACCGAAGACGTCACAACCAGCAGTACCGAACCAAAGAAGAAATCCGCGTACAGTCTGGCCCCCAATCGCGTCTCATGCCCCTACTGCCAACGCATGTTCCCCTGGTCCAGTTCGCTGCGTCGTCATATCCTCACGCACACCGGCCAGAAGCCCTTCAAATGCTCTCACTGCCCGCTACTGTTCACCACCAAGAGCAACTGCGATCGCCACCTGCTGCGGAAGCACGGCAACGTGGAGTCCGCCATGTCCGTCTATGTACCCACCGAAGATGTCAACGAGCCCATACCAGTGCCCAAGTCGGTGGAAGAGatcgagcagcagcagcgccaacgTGAAGAGGAGGAGCGTCGACGCAAGGCGGCCGAGCAATTAGAGCGCGAACGTCGTGCCCAACAGCAGGCGGAACAGCGACAACGTGAGCGCGAACGTGAGCAGCAAAAGGAACAGCAGGAGCAGCTTTTCAAGCAGCTAGCTGCCGCCGCTCAAAAAATTAACGCCGCTGCTGTCGCAGCCGCCGCGGCCGCCGCCGCAGCTGCAGCCACTGCTGAGGCGAACGGCAACACCAACTCCGACTTGCCCTACAAGTGCCACCTATGCGAGTGCTCCTTCAGTGAGCGCCTGCAGTGCCTCGAGCACATTAAGCAGCACCATGCCCAGGAGTTTGCACTGCTCCTCGCCAAGGGTGCCATCGAGACTGACGTCCTAGAGCCCTCTCCTCCGCCACCCCCACTGGTCTCTGGTGCCGGTTCTGATGAGGAGCACGGCAGCGCGAGTGCCGCTCGATCCGGAAAGTATCCAGACTACAGCAATCGCAAAGTGATCTGCGCCTTCTGTGTGCGCCGCTTCTGGTCCACGGAGGACCTGCGTCGGCACATGCGCACCCACTCCGGCGAGCGGCCCTTCCAGTGCGAGATCTGTATGCGAAAATTCACGCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGCGGACGACCCTACAATGGGGCCAACGGCACCGGTTCTGAGCACGGCGGCTCCGATTGCTCCGACGACGAGCAGTCATCGACGCCACCACCCACACCCATGTCGACCAATGCAATTGCCCCACCAACTTCAActtgccacaacaacaacaacaatagcaacaacaacagcaatatgaATACCAATAAGCTGGCCTGTCTGCGCGGTCCCAAGCTGCACGAGCTGCTGGACAAGGCGAATGAGTGGCGTGCGAGTCGCTTGGGCGAGCAGAAGGAGAACATTGGCGGAAGCGAGGCGGCATCATCGGGCACCACAGTGCCCAGCAGCGGGGACCTCATCGGTAACCTCTTGGGCATCAGCGATCAGGGGATACTCAACAAACTGCTCTCCTCACCAGACGAGGCCGCCAAGCTGTTGGGTGTGGAGAAGTAG
- Protein Sequence
- MLATQKTTTTTGSTREDETNIERQRRESTTSESSLEHLDLGRTPKKLSSSGGAPQPTSTPHNLTNGNGSAGSEQSRKRKLRHQQLQDEQPQEPLSDEEEHEAVLSHSDETSQRLRHKQRRSSGRTATASIVADYSGGDASSLRKKFRLNRSNATPAGELSESGFVDASGHSGYLLNASSASSGPVKPPVVTPSAGSSHSNSSSSSGGGSGASSPHGLSSAESGIGAVDEHMKYLCPICDVVSATPHEFTNHIRCHNYASGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCKYCHLTFTTNGNMHRHMRTHKQHQQQPAATTTATQGQRRHSHGAKNGSGAAGANAGAQRLNGGGESYESDGSCSTDVSSTNSQSSKQQQQLHNNNNNNNNTNNNNDSHKTNNNNNNSSSNIAGNLKRQQGVDAAAMSKQRRVKTTINNNIIDADVDVDVHADADADADADADDDDGGANSDVDGDIEADGDGTPATSVTTPLSSPAHVAITSTPDVATLLAGASTSPTHSSAEASLSMGLGFSCPACGAADFDNLPALCTHMDAAHADISAKCRECDVVFRSHRQLMAHPCSHRGLPGTGTESELPPLLGASSSPLHEANDDGEREDNVDADRVGEVDDEELAAAEQRVDFFRQLYLKNKAAVAGESAAMLSPIYGATATTGACGSGGEIKYEPDGKELADIQSILNMTSSSSTSNFLRNFEQTVNTPSSQYSLDGKDEEEAQDAFTSEFRKMKLRGEFPCKLCSAVFPNLRALKGHNRVHLSAVGPAGPFRCNMCPYAVCDKGALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTTREEVKRAIVYHPAEDASCDEATSTTSKNASRMQQLYGDAGDLDLADLSFRSVTPTSAPASVEQHATPVSQLKHMLLAEGQPPAKIQVKSLDQLVDKSQQQQQQQQSETKPATPATSTTPMDLSMDVLDLSKKPTAPVPTVAPVDELAAALEQQQQQQLLLSQHPLMCAGDPTQYMQQIFRNLMFQQPSPFAFFNFMPPANSANLAESLLKRMFSSAAGNSTIPPTPSSGGGNGPDKLTPSALLPQISPLMAGAEKPVSSLLPPQHPHPHAHPHQHPHAAGVPLPVGPVKMVIKNGVLMPKQKQRRYRTERPFACDHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGAAAAAAAMNSISHLSFAAGQQQSAAHHSHHQGVPGSTGGTTHISVQVKHAILAQQLKARKDTDLLQQALAHGSSSVAANPLLHFGYGHLNGAIQHCNTNGSSSSHSASSTNHNVSNNNGVIDDDEDKLVIDEDDVEEEDEEEMEEEVDEMDDDDAEEQQMHAEPATGTAADDSEDIKILPKPLEQLTKVRTPSPMAPKSPPESNEAAKKMADSILELAIKKAAKPTTVAVPATDSATSLASRPTPTPPPAHTMKTMIAQVESVAKSLKEVASSPFKDESQDLVPVSKLVDNANAASASFNTYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTTSSTEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVNEPIPVPKSVEEIEQQQRQREEEERRRKAAEQLERERRAQQQAEQRQREREREQQKEQQEQLFKQLAAAAQKINAAAVAAAAAAAAAAATAEANGNTNSDLPYKCHLCECSFSERLQCLEHIKQHHAQEFALLLAKGAIETDVLEPSPPPPPLVSGAGSDEEHGSASAARSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICMRKFTLKHSMLRHMKKHSGRPYNGANGTGSEHGGSDCSDDEQSSTPPPTPMSTNAIAPPTSTCHNNNNNSNNNSNMNTNKLACLRGPKLHELLDKANEWRASRLGEQKENIGGSEAASSGTTVPSSGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -