Sleb006480.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Scaptodrosophila lebanonensis
Gene Symbol
-
Assembly
GCA_003285725.2
Location
NW:27686285-27692669[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 10 6.2e+02 0.8 0.1 1 9 74 82 74 90 0.84
2 15 0.0012 0.075 13.1 0.4 1 23 180 202 180 202 0.97
3 15 3.7e-05 0.0023 17.9 2.5 1 23 452 474 452 474 0.98
4 15 3 1.9e+02 2.4 1.8 1 23 480 503 480 503 0.92
5 15 0.18 11 6.3 1.3 1 23 530 553 530 553 0.97
6 15 7.3e-05 0.0045 17.0 2.0 3 23 797 817 796 817 0.96
7 15 0.001 0.062 13.4 0.6 1 23 823 846 823 846 0.96
8 15 0.78 48 4.3 1.7 3 23 884 904 882 905 0.77
9 15 0.21 13 6.1 1.3 1 23 926 949 926 949 0.97
10 15 0.0035 0.22 11.7 3.2 1 23 1117 1140 1117 1140 0.94
11 15 0.00033 0.021 14.9 5.5 1 23 1155 1177 1155 1177 0.99
12 15 2.9e-05 0.0018 18.2 0.4 1 23 1182 1204 1182 1204 0.98
13 15 0.0018 0.11 12.6 3.3 2 23 1211 1241 1210 1242 0.80
14 15 3.7e-05 0.0023 17.9 0.4 1 23 1246 1270 1246 1270 0.93
15 15 9.6e-05 0.0059 16.6 0.5 1 23 1276 1299 1276 1299 0.96

Sequence Information

Coding Sequence
ATGGCTAATAAAGATGTAAAAACGGCGGGTATAGTCGACTACAATATAATATGTCGTTGCTGCCTGAAACCCGACGCCGAGCTCTACAAACTAGACTCTCTTATGGTGGCGCGAGACCTGACGCGGCAAGCAGAAGATGGTGGCAATGGTGAAAAAATAACTCTATTGCGATGTTTGCTATTCTGCATACGCACTGAAAATATTCCGGAGCTACCACTGTTCATATGCACCGGCTGCAGCAAAAGTTTGCAGATTGCGTATCATTTCATACAGAACGCTTTGCGTGCCCATGAGTTTCTGTGTCATAAGCTCAGCCCAGACAGAGAATGTTCAAAGACGCAAGCATCGGCGAAGCGCGCGGTGCGTTTTAACGGACAGCAAAATCGCTGCTTGGATGGCAGTAAAGAGAAGGCGCCAATAAGGGGCATTAAGTGCTTGGAGCAAgagGCGTTCAACAAAAAAGATGGCACTGACACAACAAAGGACAAGCGACAGACTCAGACCCAGCTGAAAGACCAACCACGCAAAAACGTACGTCATGAATGCAAGGTATGCGGCGCTGTAATATACAACAAACTAGAGCTAAAGCAGCATATACGGTTGCATTCTGACGTAATTTCACACAGTTGTAGGCTGTGTCCCTTTATTACTCTAAAGCAGCGCCAATTGAGCGATCATTATCGCATGAAGCATGACTTAACGCTAACACAAGTAGCAAGATTAAACGCGCCTGCACCCTCGAAAAAGATTGGCCCAGAGCCACCTTGTTCCTCACCAACCAGAACAAGTACAGTCGCCTGTAGTTTGAGCGCTACAAAGCCCGCAGAGGACTCAGTTGTTAAAGTGTGCACCCTGGAAGACATGGAACTTTTGATACCAACAGTTTTGAGACCGGAGGATTATACAACTCCACATATTGATTCCGAGCAATTGTGCGAAATGGAGCAGTTGAGTACTAACATGCATACAGAAGCCGAGATTGCGCCGATGACTGATTCCGCACTCAACGCGACGGCTAAATCATACGCTGAAAATTCCACTTCGGGCGAAACTTCTGACATGCAGTCAGGGAGGCACGTGAGCATAGGGACCGAGTATCTCGTTCTTCCAGATGGATCACTACAACAGTTAAACGGAAGCGGTGTTGTCATAGAATACATCAATGCATCCGTCGCCGatactaaaaataataacgatGTCAGGGCCCCTAACCTAACGCTCCAGAACTTGTTAGGCACAGCAGCGGATAATGAAGCAGCGATGGATATTGATGAGCTTATTGTTGAGGAAGTGCAGCcccaaataaaaaTCAAGGCAGCAATTGGATCTTCGCGCATGTCGACGTTCTTAAAACATAAATGCAGCCAATGCCCCAAGACATTTGCTACCTTGGCACGCTTGAAATCTCATCAATTGACTCACACCAATCTGCCAAAATTCTACTGTGATCAGTGCACTTTCTATTCGCTGCGCAGTACCGAGCTAATGGATCATTACAAGACACTGCACAACATCCAGCCAACTGTCGCCCAGGGCTTGTTTCGTAACGTAAAGGCTACAGCAGCTCCTTCAGatgtaaataaaacttacTCGTGTGATATGTGCCTCTTTGAAACCCAGAGCCGTGGACAACTACGCGTGCATTACAACAAGAAGCACTTGGTGGAACCGTCGGAGATCCAACTTAGACCTAGTTGGTCAGGTGCGGATAATGGCAACGTAGTTAAATGTGATGGAGTCCCGGGCAAACAAGTCAAGCAAACGCAACTCCCAATAGGAATTACATATGCTCCAACACCGAACCCGCCCGAACAACTTACCTTGCTAACCGCAACATCAAGTAATACCAACGAGATTATCACTACGCCGATATTAGAGTATACCACTAACTCAGATGTAGTCACAGCTACGGCGAATAGCCCACCTCAAATAATCACAGACTCAGAATTTCCATCTACAGCGGACAATTCCTTTGCAATTTTTCCGGAAAGCTCAACGGCAGCAGAACCCAAAAAGGCATTGCCTTTGGTGAGCACACAGGCTCCTATAATTGGTGATATGCAGGAATTTATTGATAATACCGATGTTGCTGCTATTTGCACGATACCAGCCGATGGAATGCCTGTGGCTGATGGGGAAGATCTTGTCATAGATAACAACAATATAAGTTTAGATTTTGATGCTGAAAATCTTTTTGAAGATTTTGAAGATGAAGATGAACCAGACGAAGAGGttgaagaagaggaagaagaggaGGATGAGAGCAATATTGATGATGAGAATGACAACAATGGTTCGGCCATTAATCAGAATTTGGTGCACACCagcgacgatgacgatgtagATGATTTTGATGATGAGCAATCAAAACACTTACAAAAACCATATTGTGTATACTGCAACAAGAAATTTACGAGTCAGTACAAGTTTGAAAACCACATGTTTGTGCATAGAGGATTGGCACCTTACCGTTGCGAGCTATGTACGAACATCTATAATCGTAAACGTGCCCTTATTCGACACTACAGGGCCGTACACAAGCGCATACCAACTCGCGATATGGTGCAGGCTAAAGGCGACAAGGTGTCGGTGGATCGCACTAACATTGAAAAGCTGCACATCGTACCGCCCAAGTATCCTGCGCTTATGTGCGCAAAATGTCCATTCGAATGTGAGCAGGATTCGGAGATGCGTAGCCATTTAAATGCACACCATGGAATCAATGATGGTGCTTCATGTCATGCTGGCGACGTATTCATTATACGCAAATTGCCCTATGAGTGTCCACGATGTATTCGCACTTTTGCGGCCAAGCACATATTAACGCGCCATCTACAGCGGAGCCATCTTGTAGATACAATCATTGAGCTGCAATCGGTGTCGAATCCCCAAACGACAAGTTCGGCTACCACAAGAACCACTTCCACAACGACCACCACTTTGCCGAACGCTGGCGAGCAAAAGGCCGCTGCCGTTGAGCAGCTAAACCAAGGACAGGAAAATAAAGAAGCAGCAGATAAATATGATCAAAACTTGAATGACACAACTGAAAGCATAATTACAACTGCAGCGGATCTCCACACCAGTATCGGCAACATCAGTGTATCCTGTTACACACCCCTCCCTACCCCGACACCGAATGATTCCTATGACTACGAATATAATTTCATTGGTCATGCACACGCCACAACAAGAGCAAGCATAGAGCACGAAAACGACAATCAGCCATCCACTTCCAGCTACCAAAGGCAGGGGTTGACTGCAGACAAGACTATGACATTTGGTATGGCGCATCAGGAGGCACAACAAAATAACAGCATGCATAATGGCTTGCCCAACACGcctatatatgtttgtaagcAATGCAACCATACTTGCACTGAACTAAGCGAGTTGCAGCAGCATCAAGCGGAGCAGCATACCATAAGCGATCATCTGTCATCGCCCCGTCGCAATTATGACTTCAAGTGCCACATATGCAACAGTACTTATCGTACAAAAACACTGTTATTGTATCACATGAAACGTCATGCGAACAGAAACTATCAGTGTGACCAATGTCCAAAGACCTTTGTGATAAAGCCAGAGCTGACAAAACATCGTGTAACCCACACAAACGAAATGCCATTTAAATGTAACATTGAAATAGATGATGGGAAAGCAGTTTGTGCGAAGACTTTCCGCTATAAGCATCACTTAAAGCGCCATCAAAATGCAAGCCATCATTTAAAGCGTTTTGCATGCCAATTTCCGAATTGCGGGCGAGAACTTGTCACAAAATCGCAGCTCAATCAACATATGCGTATGCATAAAGGTATTTTTGCATACAGGTGCCCGAAGTGCGGGCATGCTTTTTCACGACGCAGGCCTTTGTGGCTACATGCACTGCGTGCACATCAGCTAAAAATGACAGAGGACGATTTGGCAGAAGTCTATCGCGCCAATGTGGGCTACACCAATCCGCATGACTTGAAGGTATTCACGCGCAGTGGAGAACTGTTGCGGCGTCAGGATTTTGAGGCTGCTGTTGCGCAAGAGCAGCTCGTCGAGGTGGAGAATGCCGttgtaaatattataacaTAA
Protein Sequence
MANKDVKTAGIVDYNIICRCCLKPDAELYKLDSLMVARDLTRQAEDGGNGEKITLLRCLLFCIRTENIPELPLFICTGCSKSLQIAYHFIQNALRAHEFLCHKLSPDRECSKTQASAKRAVRFNGQQNRCLDGSKEKAPIRGIKCLEQEAFNKKDGTDTTKDKRQTQTQLKDQPRKNVRHECKVCGAVIYNKLELKQHIRLHSDVISHSCRLCPFITLKQRQLSDHYRMKHDLTLTQVARLNAPAPSKKIGPEPPCSSPTRTSTVACSLSATKPAEDSVVKVCTLEDMELLIPTVLRPEDYTTPHIDSEQLCEMEQLSTNMHTEAEIAPMTDSALNATAKSYAENSTSGETSDMQSGRHVSIGTEYLVLPDGSLQQLNGSGVVIEYINASVADTKNNNDVRAPNLTLQNLLGTAADNEAAMDIDELIVEEVQPQIKIKAAIGSSRMSTFLKHKCSQCPKTFATLARLKSHQLTHTNLPKFYCDQCTFYSLRSTELMDHYKTLHNIQPTVAQGLFRNVKATAAPSDVNKTYSCDMCLFETQSRGQLRVHYNKKHLVEPSEIQLRPSWSGADNGNVVKCDGVPGKQVKQTQLPIGITYAPTPNPPEQLTLLTATSSNTNEIITTPILEYTTNSDVVTATANSPPQIITDSEFPSTADNSFAIFPESSTAAEPKKALPLVSTQAPIIGDMQEFIDNTDVAAICTIPADGMPVADGEDLVIDNNNISLDFDAENLFEDFEDEDEPDEEVEEEEEEEDESNIDDENDNNGSAINQNLVHTSDDDDVDDFDDEQSKHLQKPYCVYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNIYNRKRALIRHYRAVHKRIPTRDMVQAKGDKVSVDRTNIEKLHIVPPKYPALMCAKCPFECEQDSEMRSHLNAHHGINDGASCHAGDVFIIRKLPYECPRCIRTFAAKHILTRHLQRSHLVDTIIELQSVSNPQTTSSATTRTTSTTTTTLPNAGEQKAAAVEQLNQGQENKEAADKYDQNLNDTTESIITTAADLHTSIGNISVSCYTPLPTPTPNDSYDYEYNFIGHAHATTRASIEHENDNQPSTSSYQRQGLTADKTMTFGMAHQEAQQNNSMHNGLPNTPIYVCKQCNHTCTELSELQQHQAEQHTISDHLSSPRRNYDFKCHICNSTYRTKTLLLYHMKRHANRNYQCDQCPKTFVIKPELTKHRVTHTNEMPFKCNIEIDDGKAVCAKTFRYKHHLKRHQNASHHLKRFACQFPNCGRELVTKSQLNQHMRMHKGIFAYRCPKCGHAFSRRRPLWLHALRAHQLKMTEDDLAEVYRANVGYTNPHDLKVFTRSGELLRRQDFEAAVAQEQLVEVENAVVNIIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-