Sleb010889.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_003285725.2
- Location
- NW:2909213-2912961[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.011 0.71 10.1 0.3 2 23 29 50 28 50 0.96 2 14 0.024 1.5 9.0 4.3 1 23 56 79 56 79 0.92 3 14 0.048 3 8.1 0.9 2 23 83 106 82 106 0.93 4 14 3.8e-06 0.00023 21.0 0.5 1 23 139 162 139 162 0.98 5 14 2.3e-05 0.0014 18.6 0.3 2 22 195 215 194 215 0.94 6 14 0.33 20 5.5 2.0 2 23 530 552 529 552 0.94 7 14 0.015 0.9 9.7 0.9 1 23 577 599 577 599 0.98 8 14 0.028 1.7 8.8 3.3 1 23 607 631 607 631 0.95 9 14 0.36 22 5.3 1.4 2 23 636 658 635 658 0.93 10 14 0.0003 0.019 15.0 0.2 2 21 671 690 670 691 0.93 11 14 0.0016 0.096 12.8 0.3 1 23 699 721 699 721 0.98 12 14 9.2e-07 5.7e-05 22.9 2.8 1 23 727 750 727 750 0.98 13 14 3.6e-05 0.0023 17.9 1.4 1 23 756 778 756 778 0.98 14 14 0.00034 0.021 14.9 2.9 1 23 784 806 784 806 0.95
Sequence Information
- Coding Sequence
- atggATGGCACAGGACCCAGTACAAGTGCTAGCCTCGGAGCCATGTTGGTGCAGGTCACTACGGATGGGGGCGTGCCGAAGCTGCACTGTCCGGTGTGCAACAAAGCGCTGGGCTCTCTGGCCGGCTATGTGAAGCATCTGAAGAAACACGAACCGCCTGGCGGCTTCAAATGTCGCCACTGTAACTCGCTCTTCTGCCAGGAGGATGAGCTGAAGAAGCACGTGGAGGCCACCCACGCGGAGCTGACGTGCAACCTGTGCCATGGTATGAGCTTCGTTAGTTCGGCCGCTTTGTGCTCTCACATCAACGAGGTACATCCCGATGAGGATAGGGAGAAGCACTTCAAATTCTTGAAGTTTGGCTTGGGACTTGCCACTGAGGATTCCATAAAAAGCGATAATGCCACACGTTCCTTCAAATGCGACATATGCGATAAGAGTTTGCCGACCAGACGCGATTTGAAACAGCATCAGGAGACTGTGCACAAGACTGGACCTGGACGACGCCGGGGCTTTGCGGAAAAGAACGAACGTGCGCACAACGCTACACCTTCTGCTCTGACTCCGCCCGTACGCAAGGTGGAGTGCAAGGGCTGTAACGCCACCTACTCCAGCTCCTCGAATCTAATGAAGCACAGACGCAGTCGACCGGACACCTGCGGCCTGCCCATCTATGATACGTGTACGCAACGGGGGCGTCCTCGTGGCTCACGCTCGTCCAATACTTTGGACTCATCAACTGCcgcaaaaataaaagcgaaaGCCAAGAAGACGCGAAAAAAGCACGGCTCCAATTCTTCTAGCGATGGAGGAGATGATTTCATGGACAATGATAACGTAGACAGCAGCGATGATGATCTGCCATTGGCCAACAGACTCAAGACACGAGGCCAGCAAATGAAGCAGGAGCCCATCAGCACTGCAGTCAGCGATTCGGATGAAGAGTATCCCGACTTCGAGCCCACCAATAGCGACGATGATGACTTCAAACTGCCCGCACCTGCAAAGGTAAAGGAGGAGACATACGATGATGATTTCGAGTACCAGGATGCCAGCCTCTTTGTGCAGTCCACATGCGCCGTCAAGGAGGAGGGCACAGGCAGCGAAATTTTCATCAATGAGAAGGACAAGTTGCTGGATGTGCTGCTCAGCACCGAGGAGGATGGAGTTGTGGCAACTGGCGAGACCAATCTAAAGCCATTCGAAAGTCTGAAAGTGGAGCACGCGATGCTGGATGAAATAGCCGCTGTGCCTTTGGCGGCCACAAACGAGCCGGAGTCCGTGGAGGAAGATGTTCTGGCGCTGCAAGAGCCTGCATCTCCGGaagacaacgacgacgacgatgatgatgatgatgacgaggaCTTTGAATATGACAGTGAAGCTGAGAAAAAATCTAAACGCAAGAAACAATCAAAAGCGAAGGCGTCTAAACCGACGGGTCCCAAGCGTAAATATCGAAAACGCAATGCCCCGCGTACACCGTCACCCTCATCGGACAGCCAAATGCCGAAACGTGTTGCCAAGATCAGCAAGAAAGAGCTCAAGGAACGTCTCAAGATGATCAACAAAGTGGAAAAGTCGTGGAAGTGTCCGCACTGCGTCAAAATCTATCACATACGCAAGCCGTACGAGAAACATTTACGCGACGATCACAAACTAACGCCCGAGCAAATGAAGGAGATATTCAAAGATGTCGATGCGCACGCCAAGCTGGATGAGGAGGTCTTCAAATGCAAGATATGCTCCAAGATCTATTTGGTGGAGAAACGTCTGGAGACGCACATGAAGGTGCACGGCGAGGACGGCAGTCTCACCTTTAAGTGCCCCTGCTATTGCAATCTATTCTTTGCCACCAAGGAGGAGGCCACAGCACACGCCCACAAGCAACACAAGGAGCTGCTCTACTGTGTCATCTGCGACAAGTACATGACTGGCCACGACAGCTTAAAGAACCACGAGAAGAACTTCCATTCAAAAAAACAGCCACGCAATCAGCCCCGTAATCTCATCTGCGACAAGTGTGGCAAAAAGTTTACCGGACGCACCTCTTTATCGGATCACGTGCGCTCCGATTGCGGTCGACTGCCCCTCTATCAGTGCTCTGTGTGCAGTAAACGTCTCTCCACCGCCGGCATTTTGAAAACCCACATGCTGCTCCATAAGGATGAGACGCCATACCAGTGCGACAAATGCGGCAAGACTTTCAAGGTGAAGGCTCAGTACAAATCGCATCTAAAAACGCGACACACGGACTACAAACCCTACAAGTGTCATCTCTGCCCCAAGGAATATCCCTACCGTGAAAGTCTGCTGACGCACATGACCGTCCACACAGGCATCAAGCGGTTCCTCTGCAACAATTGTGGCAAACGATTCACTTGCATCTCGAATCTCCAGGCGCATCGGAAGGTGCATGCCGACACCTGCGGCCTATTGCCCCTGAATGCAAAGGCCACGCAATATATGGGCGTGCAGCGGGGCAAGCTGTTGATGGGCGCGAAGCCCGAGGCAGGAATGGAGTATGAAGAGACCAAGACCCTCATTGCGCAGGATGTTATTGATCGCGATATGCCAATGGCACAGGAACTTAATTTTCCCTCAGAGCCATCGGCGCCGTTGGCCACTGTGCCCCTCAACTATGCCTCCTCTCATCTGGTTCCGCATATTGTGCTTCAAACCATGCAGGCGGAGGCCAGGCGCTCATCAAATTAG
- Protein Sequence
- MDGTGPSTSASLGAMLVQVTTDGGVPKLHCPVCNKALGSLAGYVKHLKKHEPPGGFKCRHCNSLFCQEDELKKHVEATHAELTCNLCHGMSFVSSAALCSHINEVHPDEDREKHFKFLKFGLGLATEDSIKSDNATRSFKCDICDKSLPTRRDLKQHQETVHKTGPGRRRGFAEKNERAHNATPSALTPPVRKVECKGCNATYSSSSNLMKHRRSRPDTCGLPIYDTCTQRGRPRGSRSSNTLDSSTAAKIKAKAKKTRKKHGSNSSSDGGDDFMDNDNVDSSDDDLPLANRLKTRGQQMKQEPISTAVSDSDEEYPDFEPTNSDDDDFKLPAPAKVKEETYDDDFEYQDASLFVQSTCAVKEEGTGSEIFINEKDKLLDVLLSTEEDGVVATGETNLKPFESLKVEHAMLDEIAAVPLAATNEPESVEEDVLALQEPASPEDNDDDDDDDDDEDFEYDSEAEKKSKRKKQSKAKASKPTGPKRKYRKRNAPRTPSPSSDSQMPKRVAKISKKELKERLKMINKVEKSWKCPHCVKIYHIRKPYEKHLRDDHKLTPEQMKEIFKDVDAHAKLDEEVFKCKICSKIYLVEKRLETHMKVHGEDGSLTFKCPCYCNLFFATKEEATAHAHKQHKELLYCVICDKYMTGHDSLKNHEKNFHSKKQPRNQPRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYQCSVCSKRLSTAGILKTHMLLHKDETPYQCDKCGKTFKVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRESLLTHMTVHTGIKRFLCNNCGKRFTCISNLQAHRKVHADTCGLLPLNAKATQYMGVQRGKLLMGAKPEAGMEYEETKTLIAQDVIDRDMPMAQELNFPSEPSAPLATVPLNYASSHLVPHIVLQTMQAEARRSSN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -