Sleb002477.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_003285725.2
- Location
- NW:51401-54785[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.016 0.98 9.6 3.6 1 23 207 230 207 230 0.92 2 17 0.00017 0.01 15.8 0.8 1 23 237 259 237 259 0.98 3 17 0.0055 0.34 11.1 0.3 2 23 291 312 290 312 0.95 4 17 7.8e-05 0.0048 16.9 0.8 1 23 405 428 405 428 0.97 5 17 2 1.3e+02 3.0 0.4 1 20 435 454 435 456 0.88 6 17 0.017 1.1 9.5 6.1 1 23 465 487 465 487 0.95 7 17 9.1e-05 0.0056 16.7 1.8 1 23 494 517 494 517 0.96 8 17 0.00016 0.0097 15.9 2.4 2 23 525 546 524 546 0.97 9 17 0.0022 0.13 12.3 0.0 2 21 573 592 572 593 0.95 10 17 0.00059 0.037 14.1 1.5 1 23 647 670 647 670 0.98 11 17 0.092 5.7 7.2 1.6 1 23 707 730 707 730 0.96 12 17 0.00018 0.011 15.7 1.4 2 23 763 785 762 785 0.95 13 17 0.0011 0.069 13.2 0.6 1 23 799 821 799 821 0.96 14 17 1.3e-05 0.0008 19.3 0.9 1 23 827 849 827 849 0.99 15 17 2.9e-05 0.0018 18.2 1.5 1 23 855 877 855 877 0.98 16 17 2.7e-05 0.0017 18.3 4.1 1 23 883 905 883 905 0.97 17 17 1.3e-05 0.00082 19.3 0.7 1 23 911 935 911 935 0.91
Sequence Information
- Coding Sequence
- atgaagcTTCCCGTAGTGTGCCGCACCTGTGATACCAGAAATGCAGAGATTCTTTATAAGCTTGAAACATATACGAAAAAGTTCCCAGAGAAAATGCTTTCTGATCTTCTAACGGAATTAACCAAAATAGAGCTTACCGAGTCCTACCCACAGAAACCCCCCCAATGCGTTTGTGGGGATTGCACGCGCAAGCTAATAGGCGCATACTACTTTGTGACACAAGCCCGCGAAGCCAACAGTCTTTTGCTGAGCCACCTTAATCGAAGCGATTCTGGTCCGATTGTGGCTGCTGTCGAAGATTGTCTAGAAGAAGCACCTATGGAGCTATGCCCCGAGCAGCATGTGACAGTTAAGATAGAAGACGACAGGGCCGACAATGACATTAGTTGTATTGAACTGCCTGAGTTTGATTTGATACAACAATCGGATGTTGCAGATGAAGCTGAAGAAGATACGAAAAAGTCGTTTGATCCGCTAAAAATGCTTGATGCTGTCAAACAGGAGACAGATGAACAAAGAGCTTCCCTATTGCAAGATGAGGAGGATTCGCTTGATGAAATGCCGTTGACACAGCGAGTGCAGCGTTGGAAGCAAGaagaacataaattaaaaaaacgtTTTAAGTGCGACCAGTGTCCCAAGAGTTTTAACAAAGTCGAGTGTATGAAGCAGCATAGTGCACGGTATcacaattcaaaaattgattgGTATTCTTGTACATTTTGCATCAGAAAATTTAGTCGTAGTGATGGCTTACAAGCGCATCTTAAAGTTCACAGCAATCCGAAACGTTCATCACATGTTGCAGACCGGAAGAAAGTTAAAGATATCGATGTGAATCTTTGTAAGCCACATGGATTCAAACTCATACAGTGCATGATTTGTCAGAGCAAATATAATAGAATCTCCGAACTGCGACGCCATTTGGAAGCGCATCCCGAGCCAAACATATCTAACATTAGAGAGCGATACAACTTGGAATTAAATGAGCTAAGGGAACTGTTTTATCCTGATTTTAAAGACGCAACTGAGGATCATTTACAAAAGCTCATGTTAAAGGATTTGGGTTCTGGTATTTATCAGCGATTCTATTCAATAACCAATCAGTCTGGCTATGAAATGGATTTGGACAGTTCGGAAACGGACAGCGAAGCCGAACAGGAAGTATATGAGCAAACTATAGGAAAGACAAAAACATCGAGAAGCTCTTCCTATCAATGCGAGTTGTGTGATGAGGGATATCAACGCAAATATCAGCTTTTGGAGCACCAGCGACAAAGCCATGCATGGTCCGAAGTGCCTCACATTTGTGGTCGTTGTGATGCGCGCTTCGTGAGCCTTCAGATACTAAGACATCATTATGAGTCGCAGTGTAAAAATGCTCAAAAGCGTTTCTTATGCCCCAAATGTTCATGCAGATTCCGCTGGAAGCATAATTTGAAGGCACACCTCCAAAAACATCGAGTCataCACACATCACACGAATGCCAACAATGTAATCGGGTTTTCGACAAGAAAAAATCACTGACTGTTCATTTGCTCAGTGTTCATGCTGATCAGTCCAAAATAATCTCGTGTCAATGGTGCCCTCGCAAGTTTTATCGTCATGACTACCTCGTGAAGCATCTAAAACGTCATGGCATTGTAGAGCAGGACATTCCACTAGCAGAGACTTTGATAGCTGCCACATCAAAGCCGAATGGTGTCAAGATCATAAAATGCAAGATTTGCAATGTCCAGTTCGACCGTATAGCCGATCTTCGTGCTCATATACAGCTGGAACTTAAGTTGTCTCTTACTTTGCATCAAAACTACGAATCTCCAAACAACTATTCTATAATAAATGAATCCGGTTTCGAAATGCATCTCGATGACTCCGAAACAGAGGACGAAACACAATCTGAATCAACTTCTGGGTTCTATAAGACTCCTACGCTATAtgtttgtgaaatttgtaGTGTGCAGTGCCCTCGGAAGTACGAAATGATGCAACATCAGCGCACCATGCATCGATTTGTCAAATTGCCGTATGAGTGCGACCGTTGCATATTCAAGTGTGTTTCCAAGAACATAATGGAGCACCATATGCAATTGCAATGCCAAAGTGAGGAGAAGAAGCACACGTGTAAAAGGTGTAGCTACAAGTTTATGTGGCCTGAAAATCTAGAACTACATGTACGATTGCAACATGGCGACAAAGATGAAGGAGCTACAGAACAAAGCGACCCCAATGGAAATAAGGAGGCGCCTGGGACTTCTAAAGGACCTGCAAATGTTGAATTACTGCAATGCCCGCATTGCGATCGAACTTATCAGCTAAAATCACGTCTAAATAATCACATTCGGGATGTACACGTCAATGGGGATCGTAAACGTAAAGAGGCGATGAAAAGATTTCTATGCTCAATCTGTGGCAAAGAGTTGCACTCGGGTGCTAGTTTGGCAACCCACATGCGGAGGCACACCGGCGAGAAGCCCTTTAAATGTGATTTGTGTGACATGGCCTTTCCGCGCTATTCAGAGATGCGCTCTCATCGCCGGATGCACACTGGTGAGAAGCCATATCATTGTACGGTCTGTGGAAAGGACTTTGCCTGGTCCGACAAACTGAAGAGACACATGCTGACGCACAGTGGTCTAAAACCGCACAAATGCAATTACTGCGAGAAGAGTTACCGGCAGTCTAAAGacttaaatttgcatttgcaacaGCACACAGGCGAGTGCCCATTCGTGTGTGGTACTTGCGGTGAGCGGTTCATACAGAGAAGCTCGTTGGAAAAACATCGCATGATGCGACGTCATTTCGATGATGAAGGAGATAGGATTAAGATAGCTATTGAATAA
- Protein Sequence
- MKLPVVCRTCDTRNAEILYKLETYTKKFPEKMLSDLLTELTKIELTESYPQKPPQCVCGDCTRKLIGAYYFVTQAREANSLLLSHLNRSDSGPIVAAVEDCLEEAPMELCPEQHVTVKIEDDRADNDISCIELPEFDLIQQSDVADEAEEDTKKSFDPLKMLDAVKQETDEQRASLLQDEEDSLDEMPLTQRVQRWKQEEHKLKKRFKCDQCPKSFNKVECMKQHSARYHNSKIDWYSCTFCIRKFSRSDGLQAHLKVHSNPKRSSHVADRKKVKDIDVNLCKPHGFKLIQCMICQSKYNRISELRRHLEAHPEPNISNIRERYNLELNELRELFYPDFKDATEDHLQKLMLKDLGSGIYQRFYSITNQSGYEMDLDSSETDSEAEQEVYEQTIGKTKTSRSSSYQCELCDEGYQRKYQLLEHQRQSHAWSEVPHICGRCDARFVSLQILRHHYESQCKNAQKRFLCPKCSCRFRWKHNLKAHLQKHRVIHTSHECQQCNRVFDKKKSLTVHLLSVHADQSKIISCQWCPRKFYRHDYLVKHLKRHGIVEQDIPLAETLIAATSKPNGVKIIKCKICNVQFDRIADLRAHIQLELKLSLTLHQNYESPNNYSIINESGFEMHLDDSETEDETQSESTSGFYKTPTLYVCEICSVQCPRKYEMMQHQRTMHRFVKLPYECDRCIFKCVSKNIMEHHMQLQCQSEEKKHTCKRCSYKFMWPENLELHVRLQHGDKDEGATEQSDPNGNKEAPGTSKGPANVELLQCPHCDRTYQLKSRLNNHIRDVHVNGDRKRKEAMKRFLCSICGKELHSGASLATHMRRHTGEKPFKCDLCDMAFPRYSEMRSHRRMHTGEKPYHCTVCGKDFAWSDKLKRHMLTHSGLKPHKCNYCEKSYRQSKDLNLHLQQHTGECPFVCGTCGERFIQRSSLEKHRMMRRHFDDEGDRIKIAIE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -