Sleb004421.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_003285725.2
- Location
- NW:5412314-5416158[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.099 6.2 7.1 1.4 2 23 113 134 112 135 0.94 2 14 0.0086 0.54 10.4 1.0 2 23 150 172 149 172 0.93 3 14 1.8e-07 1.1e-05 25.1 3.0 2 23 182 204 181 204 0.97 4 14 2.7 1.7e+02 2.6 0.7 11 23 394 406 391 406 0.91 5 14 0.0046 0.28 11.3 9.0 2 23 492 513 492 513 0.97 6 14 1.6e-06 0.0001 22.2 2.9 1 23 519 542 519 542 0.95 7 14 0.00055 0.034 14.2 0.4 1 23 547 570 547 570 0.93 8 14 0.00012 0.0077 16.2 4.6 1 23 584 606 584 606 0.96 9 14 0.00012 0.0074 16.3 1.2 1 23 611 633 611 633 0.98 10 14 2.8e-05 0.0017 18.3 1.7 1 23 639 661 639 661 0.95 11 14 9.4e-05 0.0058 16.6 0.8 1 23 667 689 667 689 0.98 12 14 2.9e-07 1.8e-05 24.5 2.7 3 23 697 717 696 717 0.99 13 14 2.1e-08 1.3e-06 28.1 1.1 1 23 723 745 723 745 0.99 14 14 0.17 11 6.3 5.6 1 19 750 768 750 773 0.89
Sequence Information
- Coding Sequence
- ATGGCCTCGTCGGATAAATTTGATCCAGACCGCGTCTGCCGTGTTTGCCTGTGCGAAGTCGACGAGTTCTACTTCATCTACGATGAGGCTCCCGTGGAGCAGGGTGCCAATGTCGCCCAGATACTGAACGAATGCACGCGATACACTTGCGAGCGGTACGATAAGCTGCCGCATCACATGTGCGGCGGCTGCATCGCTTCAGCCCGTGAGGCCTATCGTTTCAAGGTGCGCGCCGAGGAATCTTATCGCTCGCTGGTATCTATGCTGGGCAGATCGCTGCAGCCCAAGAATAATTGCACAGATGTGAGTTCACAAACTGATCAAGTCGCACTGTTGCCTTGCGAGATGTGCGATAGCAAGTTCCTGAACAGCATCGAGTTGCGTATGCATCGTAATCGCCATCATAGGGAGCAAAGCTCTGTTgccaacagtagcagcagcgaGCTTAAATGCAGGGTATGCTCAAATCAGTTTACAACGCTGCGTCAGCTGCGCACTCATTTAGCACAGGAGCATCAACAGGATATCTTTGTACAGCACCTGCAGTGTCGCATTTGCCAGCGCACCTTTTCTCGCCGGGATCACTTGGTGAGACACATGCGAACTGTGCACAGCCTTGATGAGAAGTGCAGGAGACGCAAATTGGAAGCAGCGAGTGCAGTACAGCCAGAGGAGCAGCACACAGCAACGTCTTGGTCACACGCCGGTGGTGCCAATGGGGGGGCGGTTGCATTGAGTGGTGATGAGATGGAGTCGGTACCATTCGTACTTAACGAGGCTGCCTGCGCCGATGAAAACGCTGACGACTACCAATGCAATACGAATCCCATATCCAGCAATGACGAAGATgccaatgatgatgatgaggcaAAACAATCTTTGTGGCTACACATAAAGCCAGAGCTATGGCTGAAAGTGGAGGAAGACAACGGTAACGTGGACGAAGGTGAAGGTGTATTAACGTCTCGAATGAAGCGTGAAAAAAAACGTAAAGGGAAAACGAAACAGATGGCTAGTGCCAATGAGGATGTCGTAGGTCTCGAAGGTAATGGCGATAATGAAGGCGCAGAAGCTAAGGAGGAGGGCCGTGCCAACACGGATATGGAAGTAAAAGTGGAGGCGGAACTGGTCAAAGACGAGCCGACAGATGGATCGAACATTAAACAGGAACGTCAAAGAACCGATAGCGAGCATCTAGAGGACCACATGGAGCGGCACACAAATGTGGCACAATTAACTGTCAGTGATGAGGGTGTCATAGAAGATTCCAGCGATGACGATAGCTTTGACGAACACGAAgaaaataatgatgatgatgacgaagaggatgtagaagaagaagaagatgcaGATGCGGAAATGGAACAGTTAGGAAAACCCCCTAAAGTAGAAATTGTGCGCGAATACTTGCAAAAATCCGCAAACAAACAGCGACGCCGGCGTCGCAACAAGGATGAGCCCAATCCCGAAAATCGTTGTAACATTTGCGAGCGCACCTTTTCGCGTCACTGCCATCTGTTGCGCCATAAATTGTCACATCTGGAGAAGAAACCTCATAATTGTCCGCATTGTCCGAAGGCGTTTGCGCGTAGCGACCACCTGAAAGCGCATGTCCAAAGTTTGCACAGCAACAAGGATCACAAGTGTACGCTATGCAATGCTGCCTTTGCTCGCGCCGATGCTCTCGTCCGTCACAAGGTCAGCAAACACAATGGCGAGGGTCTGGACGCCGGCAATGAATTGAAGCTACACACCTGCGAATACTGCGCCAAACGTTTCTCGAGCAAGACCTATCTGCGAAAGCACACATTGCTCCACACGGACTTTCTCTATGCCTGTAAGAGCTGCGACGAGACTTTCAAGGAGCGTCAGCAGTTGCGCGAGCATGAGAAGACGCACACGGGACAACGAAATTTCCTCTGCTGCATTTGTGGCGATAGTTTCGCTCGCAACGACTATTTGCGCGTCCATATGCGGCGTCACAATGGCGAGAAACCCTACAAGTGTCGCTTCTGCGTTAAAGCCTTTCCACGCGCCACCGACCTCAAGGTGCACGAACGTTATCACACGGGCACCAAACCGAATCTGTGCAATACCTGCGGCAAAAGTTTCCACCGAGCCTACAATCTAACGATCCATATGCGCACCCACACCGGAGAGCGTCCGTATAAGTGCGATCAGTGCCCGAAGAGCTTCACGCAAAGCAATGATCTGAAGGCGCACATACGCCGACACACCGGGGAGCGCTACAAGTGTCCCCATTGCGATGCCTGCTTCCTGCAGCTCTACAATATGCGCAATCATTGCCTGAGCGCGCACAACAAACTGATTGAGACACGCACGGGTCGCTTGCAGCGGACAGGCTTGCTGGATGATGGCAGTCAATCGCATTTAACCACTGTGGTTCTGCCACCAGCGCGCTTTCAGCACCAACCTCAGGATGTGGCTCCCCAAGTAGTGCAAGTacaccgacaacagcaacaggaacagcTGCCAACGACTATGCAGCTACTGCATTCGCCTCTGAGCTATGAGGGcgcagcagtagcaacaacatcCCCACCAGTGGttatagcagcaacaacaacaacgccggTATTGGTGGATGGCAACCAGCTAGATGTTACAACGTCCGGAACAAGCACTGCTGCCGCAACAGCCTCCCTAGGCGCCTTTAACTTTATGGCCCACCTGATGTATAATCACAGCGGTGGAAATCAGCAGAGTCAAGCAAGCAATGCGAGCGGCGGAAACGATGCGAGCAAATAG
- Protein Sequence
- MASSDKFDPDRVCRVCLCEVDEFYFIYDEAPVEQGANVAQILNECTRYTCERYDKLPHHMCGGCIASAREAYRFKVRAEESYRSLVSMLGRSLQPKNNCTDVSSQTDQVALLPCEMCDSKFLNSIELRMHRNRHHREQSSVANSSSSELKCRVCSNQFTTLRQLRTHLAQEHQQDIFVQHLQCRICQRTFSRRDHLVRHMRTVHSLDEKCRRRKLEAASAVQPEEQHTATSWSHAGGANGGAVALSGDEMESVPFVLNEAACADENADDYQCNTNPISSNDEDANDDDEAKQSLWLHIKPELWLKVEEDNGNVDEGEGVLTSRMKREKKRKGKTKQMASANEDVVGLEGNGDNEGAEAKEEGRANTDMEVKVEAELVKDEPTDGSNIKQERQRTDSEHLEDHMERHTNVAQLTVSDEGVIEDSSDDDSFDEHEENNDDDDEEDVEEEEDADAEMEQLGKPPKVEIVREYLQKSANKQRRRRRNKDEPNPENRCNICERTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKDHKCTLCNAAFARADALVRHKVSKHNGEGLDAGNELKLHTCEYCAKRFSSKTYLRKHTLLHTDFLYACKSCDETFKERQQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRFCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDACFLQLYNMRNHCLSAHNKLIETRTGRLQRTGLLDDGSQSHLTTVVLPPARFQHQPQDVAPQVVQVHRQQQQEQLPTTMQLLHSPLSYEGAAVATTSPPVVIAATTTTPVLVDGNQLDVTTSGTSTAAATASLGAFNFMAHLMYNHSGGNQQSQASNASGGNDASK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -