Basic Information

Insect: Scaptodrosophila lebanonensis
Gene Symbol: zfh1
Assembly: GCA_003285725.2
Location: NW:6762058-6768563[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.3e-05 0.0014 18.6 1.0 1 23 144 166 144 166 0.97

2 15 0.0007 0.043 13.9 1.2 3 23 174 194 172 194 0.94

3 15 0.00025 0.015 15.3 0.1 1 23 331 353 331 353 0.98

4 15 0.00085 0.053 13.6 0.9 1 23 359 381 359 381 0.98

5 15 6.7e-05 0.0042 17.1 6.0 1 23 411 433 411 433 0.97

6 15 0.00052 0.032 14.3 0.7 1 23 464 486 464 486 0.94

7 15 0.009 0.56 10.4 1.3 1 23 492 515 492 515 0.97

8 15 0.022 1.4 9.1 0.4 3 19 524 540 523 541 0.95

9 15 0.00013 0.0082 16.2 5.6 1 23 550 572 550 572 0.97

10 15 0.027 1.7 8.8 0.3 2 23 578 599 577 599 0.96

11 15 7.7e-06 0.00048 20.0 1.0 1 23 608 630 608 630 0.98

12 15 0.00087 0.054 13.6 0.1 3 23 638 658 636 658 0.97

13 15 4.7e-05 0.0029 17.6 0.5 1 23 664 686 664 687 0.95

14 15 0.035 2.2 8.5 0.3 1 23 697 719 697 719 0.97

15 15 0.0046 0.29 11.3 0.2 1 23 1263 1285 1263 1285 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.3e-05	0.0014	18.6	1.0	1	23	144	166	144	166	0.97
2	15	0.0007	0.043	13.9	1.2	3	23	174	194	172	194	0.94
3	15	0.00025	0.015	15.3	0.1	1	23	331	353	331	353	0.98
4	15	0.00085	0.053	13.6	0.9	1	23	359	381	359	381	0.98
5	15	6.7e-05	0.0042	17.1	6.0	1	23	411	433	411	433	0.97
6	15	0.00052	0.032	14.3	0.7	1	23	464	486	464	486	0.94
7	15	0.009	0.56	10.4	1.3	1	23	492	515	492	515	0.97
8	15	0.022	1.4	9.1	0.4	3	19	524	540	523	541	0.95
9	15	0.00013	0.0082	16.2	5.6	1	23	550	572	550	572	0.97
10	15	0.027	1.7	8.8	0.3	2	23	578	599	577	599	0.96
11	15	7.7e-06	0.00048	20.0	1.0	1	23	608	630	608	630	0.98
12	15	0.00087	0.054	13.6	0.1	3	23	638	658	636	658	0.97
13	15	4.7e-05	0.0029	17.6	0.5	1	23	664	686	664	687	0.95
14	15	0.035	2.2	8.5	0.3	1	23	697	719	697	719	0.97
15	15	0.0046	0.29	11.3	0.2	1	23	1263	1285	1263	1285	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGGCTATGGCGGCATGCAATGGATACAGCACCACGCATCTGTGGAGTCAGACGTTGCGGAGAACGATGTCGGGGACGCAGCTGCGTACCTTATTAACGGTAATCCAACAGAACAAGCCCTCGATCACATGGCGGCAGAAAACCTGATCTTTATGCGTGATGGACAGCTGAGCGAGATTATAGCTGCTAATGAGAACGGGGGTGCCACTGTGCTTGTTAGGGCTGACGGCAGTGCCGATGCATACGCCGACTCGTTTGACGATGACGCTCAAGTGGTCACCGAAGAAGTCATCACGGATGACTGGGTGCAACATCAGGGGGCGGAGCGCGTGGAGATAGCAGCGGAGCAAATTGCAGGCAATAGCAGCTCGCAGGAGCTGCTTGACATGGAACAGGATGAATATACAGCATTGCGCCCGTACCCATGTGACTTCTGCAGTCGACGATTTCGCAAAAAGGCCAGCCTTAACAACCATATGCTGGCACATCAAAACGATCGTCCTCACCTGTGTAAATTGTGTGGTGCTCGTTTCTCGCGCCGTGCAGAGCTCATTAGTCATTTTAAAGCGCACGCCGAGGCTCAGGATGCGGCGGATGCAGCAATGCAGGAAGCAACAGTTAAATTTGAGCCGCATCGCAGATCCATTGACGATCATTACTATGACCAAGATTGGTCGCCTTGTCCGGATCCTGTGCCCAGTAGTACCATTCAAACTGCGGATCAGACGTCTTATCCTCATGAATCAAACACCTCTCTAAGCGCTGTCGTTGTCCCGGCAGCAACGCGTGGTCGTATTAGTCGACTCAAGCCGAAGGAGGAATACATTGTGATTGCAGAAAAGCCGGCGTTAGCGGAGCTCGAATACATTGAGAGTCAGCAAGAGCAGCAGTCGGTTATTTCGAGCTTGGATTTAGCGCATGTGGCCCAGCCTGTGCAGCAGCCACAACCTCGTTTCCCCGTGCTGGACGAGAGTAAACCCTTCGTATGCCAGCAATGTGGGTTGGCATTTGCACGGGAGAAGGCGCTGGTCTCTCACGTAAAGAACCATCGTGTGGACTCCCCTTTTGAGTGCAACAAATGTCAGGAAATGTTTTGGGATAATAACAGCCTGCAAGAGCATCAGAAGTCGCATCAGTTTGAGGAAAGCAACTCTGAATATGACCCCACCTCGAGTGGAGACAGTGCCTCTGACTCCGAGCCAGAACAACTCTACGGGGACTTCTACTGCAATGAATGTGGCATCTGCTTCCACCGACAAGATCTGCTTCGCCGTCATACTAAGCAGCACGAGAAATTGGCTACAGCTAGAGCTGGTGCTCATGTAGAACCAACGTCAGGCACGACTGGTATTGGTCATGAGCTTGCTAAAGATGGGGAGCATTGCTGCAGCACATGCGGCAAATCCTTTCCCAGCGCTCTGGAGTTGTTAGCTCACGCCGAGATTCATGCGCGCTTTCCGCCTTTCAAGTGCGTCCTCTGTGGCATCAGTTTCTATGAGGAGCAGGCCATCAAGCGGCATTTACACACACGCCATCCTCACGAATTAAAACCAAACTCCTGTGTACTGTGCGGTAAGGAATGTCGAGACCGAAAGGCACTTATCAAACACGCTTGGGACCATTCTCGCGAGAAATGCCATTCGTGCTCTAAATGTGGCAAAAATTTCCATAACAAGGCTCGCCTGAAGCGTCATATGGCGTCACATCGCGACAAGTCAGTGGTATGTGAGGTGTGCCAGGAAGAGTTTCCCGACGGCCGATCGCTCTCCAATCATCGCCACTCACACAGCACCACATCTCCAGGAAAACTGTTTCCATGCCATGAGTGCGGAAAAACATTTGGCTCGCGCAGCTCGCAGCAAATCCATGTTCGCATCCACACGGGCGAAAGACCCTACGGCTGTCGCTACTGCTGGAAGGCCTTCGCTGATGGCGGGACTCTCCGCAAACATGAGCGCATTCACACCGGCGAAAAGCCTTACGCCTGCTCCGTGTGCCCTCGTGCCTTCAACCAGCGCGTCGTTCTTCGCGAACACATACGCTCCCATCACTCGGGATTAGATGTGGAACGTGGCACTTACCACTGCACGGTTTGCGAAGCGGATTTGACTTCCTCCAATGATCTAATACAACATCTTATACAGCACAGCGACACAAACACGGCCAAGCAACGGCAACCTGTAACCGGACCACGGAAATACAAGCGCCGGCGGAAGCTGCAGCCGCACGAGATTGCGCACTTGTGCGCCAAACCAAAGGACCCCGAATGCGACGATTACGGTAGCGACATTGACATCGGTGACTTTGATGTAGACAATGTGGAagatttgtttgaaatatCGGAACCAACCAAAAAAGGGACTGGAAAAGATAAGCGCAAAAGGGGCGCAGTTGAAGGTGTCAAAAAATCAATGGCCAATGGGAGCAATACGTCAGCTAGTACCAAGTCTGAAGCAAGTGCGCAGGGCGCACAGACGGTGGCAAAATCGAATGTAGAAAAGCCACGCTATGACTCAACCAGCAGCACTTCGGACAGACTATGGGAGGAAAAGTTTATGCATGGAAGTGGACATCCTAGTGATGATGCTTACAAAACCCTCTTTCAGATTGACTCGCTGGTGGTAGTAAATGACACGGCGCTGCCTGTGGAAACGCCTGCCAGCGTGGTAAAAACGCGGCGTAACGTCAAGCATAATGTGAATACGGAGCCACAGGCACTTAGCATGTCGACTACGGCGTCTGCGTTGGAAGCCAAAAACAATAGTCATACTGGTGGCAGCTCTAACAGTCGCAGTAGCCGCAAGAAACTGGCCAAGGCAGCAAAGGGTGCAGCCCCGACAACACGACCTCGAATGATACATACCGAGAAATCGCGTGTGCAGCCGTCGACGGAGACTGTCAGTGGATCAAAAAAAACGCGCGGGAAAATGTACGTGACGCGCACCGAAACCAACAGTCCGGTTCAGACCAGTGCCTCTGCAACACGTGCTAGTTCTTCGACCATGGTCGATGATTATGAGATCATTTCACCCGCCACACAGCCACCTAATCAGATAAGCTCTAGTCCGCTGCACATTAaacaggagcaggagcagcaacagcgtgTGCAGCTCATGTACGATGACACACACCTGTTGCTAGACGCGACGCTTCGTGAGAAGGCATACGAAAAGTTTAATCCAAGCATTGTCAACGATCTGGAGGAGATTCTGCGCTCCCCTCTTAAGTCTGATCGCAATGCGCGCCTACGCTTCATTAGCGAGTCATCTACGACGCCACAATTTTTACCGGATGAGGAGCagaatttaatcaaaattgagCCTACATCACCGGATCTGCGCGAAATGGTCGAGAGTCAACAACGAGTCACAGCCTCAACAGGCCCTCCCGCTTCGTCCGCAAGGACCACACGCCACCAGAGACAGTCACAAACTACCAATAACAAATATCTGCCAGAGAGTATGCAGCAAAATAACTCAAAAGTGTCCATGAAGCGACTCAGTGCCAGCAAAAACGCACCTGCCTCGAAATCTAAGAAACCCAAAACGACCTCACCGTCAGCTATGACTGCCAAAGTCAATGATACCAACAGCTCGACCACCCAGTCATATCTTGGCTACGTGGACTCGTTCAATGTGAATGTACCTGCCAGCTCTAACACTGCCGATGTCAGCTCGGGTTTCTTCTCCATTTCCGAGGTCGTTTCAGCTGCGGATGCAGCTGATGCAGCGGCCAAGGCGGCAGCCACGAGTAAACCGGAGCGCAAGGCACGAACTTTCGAGTGTGAGATGTGTTCGGCAATATTCTACGATCGAGCCCAGCTGTTGGAACATGTGCACATTCATATATAG
Protein Sequence: MNNQGYGGMQWIQHHASVESDVAENDVGDAAAYLINGNPTEQALDHMAAENLIFMRDGQLSEIIAANENGGATVLVRADGSADAYADSFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGNSSSQELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAAMQEATVKFEPHRRSIDDHYYDQDWSPCPDPVPSSTIQTADQTSYPHESNTSLSAVVVPAATRGRISRLKPKEEYIVIAEKPALAELEYIESQQEQQSVISSLDLAHVAQPVQQPQPRFPVLDESKPFVCQQCGLAFAREKALVSHVKNHRVDSPFECNKCQEMFWDNNSLQEHQKSHQFEESNSEYDPTSSGDSASDSEPEQLYGDFYCNECGICFHRQDLLRRHTKQHEKLATARAGAHVEPTSGTTGIGHELAKDGEHCCSTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRSLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVERGTYHCTVCEADLTSSNDLIQHLIQHSDTNTAKQRQPVTGPRKYKRRRKLQPHEIAHLCAKPKDPECDDYGSDIDIGDFDVDNVEDLFEISEPTKKGTGKDKRKRGAVEGVKKSMANGSNTSASTKSEASAQGAQTVAKSNVEKPRYDSTSSTSDRLWEEKFMHGSGHPSDDAYKTLFQIDSLVVVNDTALPVETPASVVKTRRNVKHNVNTEPQALSMSTTASALEAKNNSHTGGSSNSRSSRKKLAKAAKGAAPTTRPRMIHTEKSRVQPSTETVSGSKKTRGKMYVTRTETNSPVQTSASATRASSSTMVDDYEIISPATQPPNQISSSPLHIKQEQEQQQRVQLMYDDTHLLLDATLREKAYEKFNPSIVNDLEEILRSPLKSDRNARLRFISESSTTPQFLPDEEQNLIKIEPTSPDLREMVESQQRVTASTGPPASSARTTRHQRQSQTTNNKYLPESMQQNNSKVSMKRLSASKNAPASKSKKPKTTSPSAMTAKVNDTNSSTTQSYLGYVDSFNVNVPASSNTADVSSGFFSISEVVSAADAADAAAKAAATSKPERKARTFECEMCSAIFYDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -