Sleb009617.1
Basic Information
- Gene Symbol
- su(Hw)_1
- Assembly
- GCA_003285725.2
- Location
- NW:716900-726501[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00052 0.032 14.3 2.2 1 20 239 258 239 260 0.94 2 12 2.2e-06 0.00013 21.8 0.4 3 23 311 332 309 332 0.93 3 12 0.036 2.2 8.5 0.1 1 23 338 360 338 360 0.95 4 12 4.3e-07 2.6e-05 24.0 2.4 1 21 367 387 367 388 0.95 5 12 2.5e-06 0.00016 21.5 0.6 2 23 400 421 399 421 0.96 6 12 4.6e-05 0.0029 17.6 5.4 1 23 432 454 432 454 0.99 7 12 6.3e-05 0.0039 17.1 0.9 1 23 460 482 460 482 0.97 8 12 7.3e-06 0.00045 20.1 0.7 1 23 488 510 488 510 0.98 9 12 1.2e-06 7.2e-05 22.6 3.0 1 23 516 538 516 538 0.98 10 12 1.7e-05 0.0011 18.9 1.2 1 23 542 564 542 564 0.97 11 12 0.0022 0.14 12.3 0.2 1 21 572 592 572 596 0.91 12 12 0.00012 0.0074 16.3 0.2 3 23 615 636 613 636 0.96
Sequence Information
- Coding Sequence
- ATGACGAAAGCGTTAGCAATAACGAAGACAAACAGGAAAAGTGAGGGAATTCCAATGAGCAAGGAGGACAAAGGAACGACTGATGCAAGTCTCAGTAGTGGTGTGATCAAAGTTCTAGGTGTAGAACATAATCCGCCACCGAGAGAGAAACGTTCCGTCAATACACCCAGTAGTGGGACGCGTTTAAAACTTCTTAACGATGTTGCAGCAGCAGGTGGAGGGAAGGCCACATTGGGCTCGTATACTAAGCCAGATAAACGACTAAGCAGCGGCAGTTCCCGTATAAAAATACTCAATGAGGATAGCATAGCAACCAAGGCCGCTAAACGCAATAGCGCTGGCGCTTCCAATAAAACCATTCCGAACACAGCCACCGTCAAAATATTAAACGACAAACGCATTGTATCTGCTGCCACACCtatagaaacaacaaaaatcaagaCACCGCCCAcaaggaaaaagaaaatggaTCACTATGTGCTTCATGCTGTAAAAGGCGAAAATAATAAAGCTGATACAACCTGCAGTGTGattgttgatgatgatgatgatactATAGACTTTATACTTGCAGAGgaaaatatcaacaacaaagATCAGGCCAGCGAGCCAGTAGCCGAAGAGCTCACGGTATctgaagaagaagatgaagatGGGGAAGAAGGAGAACCCCGTTCCAGTGCAAACAGTAGCGACATTAAAGAGATTGTAGAACACGTATGTGGAAAATGCTATAAAACATTTCGACGCGTCAAGAGTCTTAAGAAACACTTAGAGTTTTGCCGATACGATAGTGGATATCACTTGCGCAAGGCAGATATGTTGAAAAACCTGGATAAAATCGAAAAAGATGCTGTTGTCATGGAAAAAAAAGATATATGCTTCTGTTGCAGTGAAAGCTATGACACTTTTCATCTGGGCCATATTAATTGTCCTGACTGTCCGAAGTCGTTTAAAACCCAGACAAGTTACGAGCGTCATATTTTCATCACTCATTCGGAGTTTAATGATTTTCCTTGCTCTATTTGCAATGCAAAGTTGCGCAGCGAAGCTCTTCTTAAACTGCACGAAGAACAGCACAAGATACGTGGAAAGCCATATGCATGCAAAATATGCGGGAAGGACTTCACGCGTTCCTATCATCTTAAGCGCCATCAAAAATACTCATCTTGCTCAGCCAGTGAGAACGATACCATGAGTTGCAAAGTGTGCGATAGAGTGTTTTATCGACTAGACAACTTGCGCGCCCACCTGAAACAGCATTTAGGCACACAAGTCGTAAAAAAACCAGAATACATGTGTCACATTTGCAAGAACTGTTTTTACAGCCTGTCCACGCTAAACATTCACATACGCACCCACACGGGTGAAAAGCCTTTTGATTGCGATCTGTGTGACAAGAAATTCTCTGCTTTGGTAGCGCTTAAGAAGCATCGGCGCTATCACACTGGTGAGAAGCCTTACAGTTGCACAGTGTGCAATCAATCCTTTGCTGTCAAAGAAGTGCTTAATCGACACATGAAGCGTCACACGGGCGAGCGCCCGCACAAGTGTAATGAGTGCGGCAAAAGTTTCATACAAGCTACTCAGCTTCGTACGCATTCTAAAACACATTTGCGTCCGTATTCGTGCGACCAATGCGATGAGAAGTTTAAGACGGAGAAACAACTCGACCGACACATTAAGGATCACACGCGGCAAAAGCGCGCGTCATTCATTTGCTCGCTATGCAATCAGGGTTTTCGCACAGATGAACTGCTGAAACAGCACATAGAAGAGGGCAAACACACTCCCAAGACCACGCGACCCAAACGCTCCGCGAAAGTTATTGAGCGCACCGACTGTGCCATTTGCGATAAAAATTTTGACAGTACCGACAGGCTACGCGCCCATATACGCAGCGTCCATGAATGTAATCCGGACGATATTTTCGGCACGGAGCCCCATGCCGCCAAACGCACAAAGAAGACAAAGAAGTTATTAGAGACTCCTTCAAACACATCTGGCTCGCTTATTTCCAGCAAAACGAACAGCAATGGCGTCGTTGTGCGCGAGTATCTTGTCGATGAGGGCGATGGTATTACACAGAGTATAACGCTTGAGAATGAAACCTACACTATATTGCCTTTGAACGAAAATCAGGAGTcgataataacaacaaatattgaaactgAAATTGCAGCTGCAACGCCTGATGTGAAGCCAGAATCAAAAGAGCAAATGTCACCCATGGTTAAGAAGGAACAGCGAAAGTCACTGGCAGCCAGCTTAGCAGCGGCCATAGCTGACAACGGCAGCGAATCTCTCAGTGACGATGAGCTTAACAGTGATGTTCTGTCCGAAAATGATTTAAAGCTAAAGGAGAATATAGGCAAGCTGATTGATATGCTGGTCGATCCGCCTACATTACAAAAGTATGGTTGGCCCAATACATCCGAAGAAACTGTACTCTGTAAGGTGATTGAAAACTGTGGCCATGACCTGACGCGAAGTGGCGAGAACTACGCAGAGTTGGACTATGGCACTCGAATGCGTGAATATGCGAAGCTCCTGTTTACTGTTGTCATACACAACGACTCCATCAAGTCACTTCTCAATAACTTTCCCATTGATGACGTTATTGAGTATGTACTGGGAAGTGACGATGATCAAGACGAGGGGAAGGATGATAAGGGCCGTGATCAGTTGGGGGCCAAAACTAGTGTCATCAATGTAGATGCTTAA
- Protein Sequence
- MTKALAITKTNRKSEGIPMSKEDKGTTDASLSSGVIKVLGVEHNPPPREKRSVNTPSSGTRLKLLNDVAAAGGGKATLGSYTKPDKRLSSGSSRIKILNEDSIATKAAKRNSAGASNKTIPNTATVKILNDKRIVSAATPIETTKIKTPPTRKKKMDHYVLHAVKGENNKADTTCSVIVDDDDDTIDFILAEENINNKDQASEPVAEELTVSEEEDEDGEEGEPRSSANSSDIKEIVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLDKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDFPCSICNAKLRSEALLKLHEEQHKIRGKPYACKICGKDFTRSYHLKRHQKYSSCSASENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHICKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYSCDQCDEKFKTEKQLDRHIKDHTRQKRASFICSLCNQGFRTDELLKQHIEEGKHTPKTTRPKRSAKVIERTDCAICDKNFDSTDRLRAHIRSVHECNPDDIFGTEPHAAKRTKKTKKLLETPSNTSGSLISSKTNSNGVVVREYLVDEGDGITQSITLENETYTILPLNENQESIITTNIETEIAAATPDVKPESKEQMSPMVKKEQRKSLAASLAAAIADNGSESLSDDELNSDVLSENDLKLKENIGKLIDMLVDPPTLQKYGWPNTSEETVLCKVIENCGHDLTRSGENYAELDYGTRMREYAKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGSDDDQDEGKDDKGRDQLGAKTSVINVDA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -