Basic Information

Insect: Scaptodrosophila latifasciaeformis
Gene Symbol: lola_2
Assembly: GCA_037075145.1
Location: JBAMCM010000146.1:184763-199344[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0004 0.034 14.8 0.4 1 22 528 549 528 549 0.97

2 9 0.046 3.9 8.3 3.2 1 23 557 580 557 580 0.93

3 9 0.0013 0.11 13.2 0.3 2 20 693 711 692 713 0.94

4 9 0.00013 0.011 16.4 0.5 1 20 721 740 721 742 0.95

5 9 0.00013 0.011 16.4 2.4 1 21 932 952 932 953 0.97

6 9 0.00069 0.058 14.1 3.9 2 23 962 984 961 984 0.96

7 9 5.1 4.3e+02 1.9 6.8 1 23 1387 1410 1387 1410 0.96

8 9 8.9e-05 0.0075 16.9 0.7 1 21 1428 1448 1428 1449 0.96

9 9 0.05 4.3 8.2 4.7 1 23 1458 1481 1458 1481 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0004	0.034	14.8	0.4	1	22	528	549	528	549	0.97
2	9	0.046	3.9	8.3	3.2	1	23	557	580	557	580	0.93
3	9	0.0013	0.11	13.2	0.3	2	20	693	711	692	713	0.94
4	9	0.00013	0.011	16.4	0.5	1	20	721	740	721	742	0.95
5	9	0.00013	0.011	16.4	2.4	1	21	932	952	932	953	0.97
6	9	0.00069	0.058	14.1	3.9	2	23	962	984	961	984	0.96
7	9	5.1	4.3e+02	1.9	6.8	1	23	1387	1410	1387	1410	0.96
8	9	8.9e-05	0.0075	16.9	0.7	1	21	1428	1448	1428	1449	0.96
9	9	0.05	4.3	8.2	4.7	1	23	1458	1481	1458	1481	0.94

Sequence Information

Coding Sequence: ATGGAGGACGATCAACAATTTTGCTTGCGCTGGAATAATCATCAGAGCACGTTGATTAGCGTGTTTGATACGTTGCTGGAAAATGAGACGCTAGTCGATTGTACACTCGCTGCCGAGGGCAAATTTCTCAAGGCCCACAAGGTGGTGCTGTCAGCATGCAGTCCCTACTTTGCTACCTTACTTCAAGAACAGTACGACAAACATCCAATTTTCATACTCAAGGATGTCAAGTACCAGGAATTGCGCGCCATGATGGATTATATGTATCGTGGCGAAGTGAATATATCGCAAGATCAGCTGGCCGCTCTGCTGAAGGCCGCCGAATCGCTGCAGATCAAAGGTCTGTCAGATAATCGCGGTGGCGGCAACTCGGCTGCAGCGCCCAAGCCAGAAACACATCACCGTGGCAAATTAGGTGGCGCCTACACCTTGGAGCAGACGAAGCGTGCTCGCATGACAACCGGTGCCATGGATGCACAGGATGTGTCTGGCTCACGCGAAGGTTCCTCCAGTCCGTCGCGGCGTCGTAGAAAAGTTCGACGCAGGAGCATGGAAAATGacGCCCACGACAATTCCAACTCATCTGTGCTGCAAGCCGCCGCCTCCAATCAGTCAATCCTCCAACAAACGAGCGCCGGTTTAGCTGCTTCCGCTCTGGTCGCCACCCAAATGCCCAGCTCGGGTGTTGGTGGAAATATCGCAACCGGAAGCAATACAGGCGCCAGCCAAGTTACGACCCAGCCATTGACCAGCACCAATGTTACCAAAAAGACTGAAAGCGCTAAACTAACATCGACAGCCGCCCAGggcgtcgctgctgctgccgctgccggcGGTAGTGTCGTCAATgcaggacaacaacaaacaggcGATGCCATCAACACCGACAATGTACAAACAATTGGCGCCCAAGGCGCCCATGTTGGCGCTGGCGGTGATATTGACGATATGGATGTGGCTGGTGGCGGTACTGTGCACACTGGCGTGGTCAAGCAATTGGCTGCCATTGAAAAGTCGAATCACAAGCAAAAGAACAAGGATAATAGCGTCTCATCGGCTGGCTCCGAATTGGCCATTGAGCCGAAAGCCGAATACGATGATGATGCCCATGATGAAAATGTTGAGGATTTGACTTTGGATGAGGAAGATATGACAATGGAGGAGCTGGACCAAACGGCCGGCACCAGTCAGGGTGGCGAAGGATCTAGTCAAGCATATGCAGCATGGCAACACGACAGATCTCAGGACGAACTCGGACTAATGGCCGGACAGGATGCACAGCAACGGGATCCACAAGTGCGTGGCAGCTCGAAACGCATAGCCCGAAGGAAACCGCCGAGCTTAATGGCGGCGCCCACAGCGGTTACCTCGTCACCCCACCACACCCGTAACATGGGCAGGCGCAGGCGTAAAGCGATACCCGCCGCCACCAAATCGCGCAGAACTGCCACTGCGTCTTCAGCTGGGGTTGCCGCCGCCGCAGTTGCCACAgtgacagcaacagcagcagcagatggTTCAGCGGCAGCTggttcctcctcctccacgtCGACCTTGGCAGGGGCCGATGGTGCAGCACCCTATGTGTGCCAGACCTGTGGTCGCAGATACCAAGTCCTGGGCACCCTGACGCGCCACATGCGCAAAGAGTGCAATCAGCCCAAGAAGTTTGTCTGCCGCATGTGTGGACGTGGctttcattataatttcaaattgcaaGATCATTACTATTACGTACATAAGGATCTGCTTGAGCTGAGCTTGAATCAACCAACCTATAGCCACTTATATGAGCAGTCCATGctaccgccaccaccgccgctcTCACAAGCACcgacggcagcagcagcaacaaggcCTCCGCGCACTTCGCCGCGCCAGCGTAAAACCAACTCTGCCAATGCCAACAGAACAAAtcatagcaacaacaacagcaaatcgaataaaaatcaagatgAATTGAATACTTCACTTCAAACGCCACCACCCCCACTAACCGCGGCCGGGAATGGCCACACAAATGCTGCAGCCCTGGCCTTGGCCAAATCAGCTCAACAGGGTGCCGACGGCAAACTGAAATGTCCACAATGCTCGAATTCCTATTCCCGCCAATCGGTCCTCAAGCGGcacattgaatttgaatgcGGTCAGCTGCATAATTTTCGTTGTCAGATCTGTGATGCCGGTTTCAAGCGTAAAGATTCACTTTATCGGCATTacTTGCTGATGCAACAACATCaccatcacaacaacaacaacaacaacagttatACAGCCTTGGGGGCCGAAAGCCCACAGGCGCGGCACAACAagtacaataacaacaacaacagcaatggcagcagcagcaacaacaacaacaattgcaataagCAAAAGGAATTGTTGATGAATCACAAAGAAgccaaaaccacaacaacaacaaccactgacaatcaacaacaacaccaccacctccatcatcagcaacaacaacagcagctcaGTGACTTGCACTTGcattttcaacaacaacaaacggcaacaacaatttgcacAAAAGCCCACACCCCCCACACAGCCTCCTCCTCATCtttacaacaaccacaacaacaaccacaaacaGCACCTTCAGCCTTAACGTCCAACTCTGCCCTCTCCTCCTCTTCCACCTCCTCTTCGCTTCAGCATTTTCCAGCTCCGTCCAATCAACATAATTTTGAACACTTTCAGGCAGTCCTGACTGCCCCGGccacctcctcctcttcctcaTCGACTGCTGCTGCCAGCTTGATGGGTCTGGGCGAGATGAGCTATACCTGCCCGCAGTGTTATCGAACATATCGCCGCCATGGCACCCTGCGCCGTCACCTGCGCCAGGAGTGCGGCAAGGGCAAGAGCATGGTCTGTTCGGTCTGCGGTCACCGCACCAAGCGAGCCGACCACCTGCGTCAGCATGTCCGTAAGAAGCATCCAGAAATTGCCTTGCGTTCCCTTTTcaaacggcagcagcagaggGCGGCCGCTGCTGCCTCCACCACAACAGAGGCTGCCTTGGCCACCAGTGGTGGTGCCCTCAAACCGGATATTGTGGATCTGGATCTGCtggacgatgatgatgatgtggaGGTGGCCCCTTGCCCAGATGATTTTCCCGACGAGGAAAATCCAGCTTCCTTTGCCTTGGGTCTAATTGAAGAGGATGGTGATAATGAGCTGGAGGATATGACTCCGGTCACGGAGGATGAACGCTCCGCTGCCAAGTTCTACCAGCAGCAATTGCATCAGCAGGCTCTgcagcaattacaacaacagttccaccagcaacaacaactgcaggCCTTGGCGGCGGCAGCCGCTGCGGCTGCTGTGGCCAAGTCCAAGGCAGGCGGTGGTGCTGGCGGGGGCGAAGCCGGAAGCAGTGGCGAGGCCACCCTAAACTATTTAAGGACGCTGTATTGCAACTttgccacagcagcagccgcgGCTGCGGCAGTTGCAGCGGTGGCCAGTGTAAccgagaacaacaacaacaacaacagagtggccacccccaccagcaacaatggcggcggcggcagtcCCATAGAAAATGTGCCACAAACGCGGACCACAGTCTCGCCCAACCAGCTGACgtcatcaacagcagcagcaacaacaacaacaacaaccgcaatGACAACTGCCCTGCGGCAAAAGCCAATACAGAATTTTAAtagccataaaaatgcaacTGATATGCGTGAGATCTATGAGCCCGAGGTAACCATACGCCGCATGTACAAATGTGGTGGAGGgggtggaggaggaggtgggCAACAGCCCAGCGGCAGTCAATTGCCTTGCAAGGCCTCGGCCAACTGCAGTGGCTGTCAAATGTCTGCGGCAGCAGCCACCTTCCAATTGGCCAATTTGCTAAACTCCACCATGCTAATGCCTCCTaacgctgctgccgccgcctcCACCAAGTCCCCCTCCGCCGCAGTTAATACGCCAAGTTCAGTCGGTGTCTTTGGCAGCTCCtcggccgctgctgctgccgccaaagccaaagcaggcAGCTCTGCTGGTTCTGCTGCGGTCAAAGCCGCCACGCCAGCCGGCAGCAACTCCTCAGctgcggcggcagcagcggccgcCCTGCTCATGGCTGCGGCCACCAAGAAACCCAGTGTGCAATTCCACTGCGAATTCTGCAGTTTCTCCTGCACCTGGAAATACGATCTGAAACTGCATTTGCGGCAGAAACACGGCATTCATCAGCtcaagaaaatCGTCTACGGCGGAGATTCCCATGAGCGCTTCCCCTGCGCCGTCTGCGGCAAAAGTTATCTAAGGAAACGCCACCTCCAACGGCACATGCGAGATGAGTGCATCGGTATACCGCCGCGTTTCAATTGCGAATTCTGCTCCTCTCGTTTCCGTCGCAAATATCACATGGTCCGTCATCTGGTCTCCAAGCATGGCATACCACCGGCTATAGCCCAACAGACCACCGGCAGTGGCTCCCGCACCAGCAGTCCCCGCACGAATGCCTCGTCAGCGGTTGGTGGCGCCAGCTCAATCGATCTGAAGTTCGCCCTGGGCGGCGGTGTAGGCGGCGATAGTGGCAGTGTGGGCAGCTCCGGCTCCCAGAATGGTTGTGAGAGTCCCTTGCCGGAGAATCTGTCCTTGCGCAAGGAGAACTATGAGAACGAGCCGAATTCTCGCGGCACCTCGCCCTTGCCCCACCATCTGATGCCCATACCCACATATGGTCTGACCGGTGCCATTACGGCCATTTCGGCGGCAGCTGCCGTAGTGGAAGAGCAGGCCGCAGCGGCCCAGGCGGCGGCGGTTGCTGCCGCAGCAGCCATGGCGGTTGCTgccaaatcgaaaaataacaatgagaacaacagcagccaaggCAATGGCGGCGAAGATGCCAACTTGGAGGCTGATAATGCCGACGGTGCCACCGGGCCCGAGGTGGTGGGCCTAACTGTTAAGGCTGAACCGGTCACGCCCACCAAGGCCCAGCAGCTCATCGACGAGGAATGGAACATGAAGTTGGGTCTACAAATCATATCCAATTCCCTGCTCAAGGAGCGCCTCATGAATACAATGCCATTtgcttacaacaacaactaa
Protein Sequence: MEDDQQFCLRWNNHQSTLISVFDTLLENETLVDCTLAAEGKFLKAHKVVLSACSPYFATLLQEQYDKHPIFILKDVKYQELRAMMDYMYRGEVNISQDQLAALLKAAESLQIKGLSDNRGGGNSAAAPKPETHHRGKLGGAYTLEQTKRARMTTGAMDAQDVSGSREGSSSPSRRRRKVRRRSMENDAHDNSNSSVLQAAASNQSILQQTSAGLAASALVATQMPSSGVGGNIATGSNTGASQVTTQPLTSTNVTKKTESAKLTSTAAQGVAAAAAAGGSVVNAGQQQTGDAINTDNVQTIGAQGAHVGAGGDIDDMDVAGGGTVHTGVVKQLAAIEKSNHKQKNKDNSVSSAGSELAIEPKAEYDDDAHDENVEDLTLDEEDMTMEELDQTAGTSQGGEGSSQAYAAWQHDRSQDELGLMAGQDAQQRDPQVRGSSKRIARRKPPSLMAAPTAVTSSPHHTRNMGRRRRKAIPAATKSRRTATASSAGVAAAAVATVTATAAADGSAAAGSSSSTSTLAGADGAAPYVCQTCGRRYQVLGTLTRHMRKECNQPKKFVCRMCGRGFHYNFKLQDHYYYVHKDLLELSLNQPTYSHLYEQSMLPPPPPLSQAPTAAAATRPPRTSPRQRKTNSANANRTNHSNNNSKSNKNQDELNTSLQTPPPPLTAAGNGHTNAAALALAKSAQQGADGKLKCPQCSNSYSRQSVLKRHIEFECGQLHNFRCQICDAGFKRKDSLYRHYLLMQQHHHHNNNNNNSYTALGAESPQARHNKYNNNNNSNGSSSNNNNNCNKQKELLMNHKEAKTTTTTTTDNQQQHHHLHHQQQQQQLSDLHLHFQQQQTATTICTKAHTPHTASSSSLQQPQQQPQTAPSALTSNSALSSSSTSSSLQHFPAPSNQHNFEHFQAVLTAPATSSSSSSTAAASLMGLGEMSYTCPQCYRTYRRHGTLRRHLRQECGKGKSMVCSVCGHRTKRADHLRQHVRKKHPEIALRSLFKRQQQRAAAAASTTTEAALATSGGALKPDIVDLDLLDDDDDVEVAPCPDDFPDEENPASFALGLIEEDGDNELEDMTPVTEDERSAAKFYQQQLHQQALQQLQQQFHQQQQLQALAAAAAAAAVAKSKAGGGAGGGEAGSSGEATLNYLRTLYCNFATAAAAAAAVAAVASVTENNNNNNRVATPTSNNGGGGSPIENVPQTRTTVSPNQLTSSTAAATTTTTTAMTTALRQKPIQNFNSHKNATDMREIYEPEVTIRRMYKCGGGGGGGGGQQPSGSQLPCKASANCSGCQMSAAAATFQLANLLNSTMLMPPNAAAAASTKSPSAAVNTPSSVGVFGSSSAAAAAAKAKAGSSAGSAAVKAATPAGSNSSAAAAAAAALLMAAATKKPSVQFHCEFCSFSCTWKYDLKLHLRQKHGIHQLKKIVYGGDSHERFPCAVCGKSYLRKRHLQRHMRDECIGIPPRFNCEFCSSRFRRKYHMVRHLVSKHGIPPAIAQQTTGSGSRTSSPRTNASSAVGGASSIDLKFALGGGVGGDSGSVGSSGSQNGCESPLPENLSLRKENYENEPNSRGTSPLPHHLMPIPTYGLTGAITAISAAAAVVEEQAAAAQAAAVAAAAAMAVAAKSKNNNENNSSQGNGGEDANLEADNADGATGPEVVGLTVKAEPVTPTKAQQLIDEEWNMKLGLQIISNSLLKERLMNTMPFAYNNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01319119;
90% Identity: iTF_01319119;
80% Identity: iTF_01319119;