Slat006448.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_037075145.1
- Location
- JBAMCM010000123.1:13540566-13541773[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 1.5e-05 0.0013 19.3 0.5 2 20 163 181 162 184 0.92 2 7 0.59 50 4.8 1.0 1 21 189 209 189 213 0.89 3 7 0.0018 0.15 12.8 2.8 1 23 226 249 226 249 0.97 4 7 0.00077 0.065 13.9 0.7 1 23 256 278 256 278 0.98 5 7 3.1e-06 0.00026 21.5 1.8 1 23 289 311 289 311 0.98 6 7 3e-05 0.0025 18.4 3.1 1 23 317 340 317 340 0.98 7 7 0.00064 0.054 14.2 3.3 1 23 346 369 346 369 0.96
Sequence Information
- Coding Sequence
- atgtcaaaagaaCTGTGCAAATTATGTTTGGAAAATCCTGCAGGCAGTGAGTTACTCAAGACCAAAGGATTTATGTCGGCCGCCAATCTACTGGAGCGGCTTTTCGAAGCCTACGAAATCGAGTGCTCCTACGAGGACAGCGTCTGCCAATGTTGTTTGGCCGATGTCCTGGGAATATGCGATTCACTATGCAACTGGCAGAAGGCTCAACAATTACGCACAACCACCACAATTATTGATGAAGAGTTGGAGCAAGAAATAAGCCTCATTATACAAAACGACGAAACAGAGGACCAGCTAGATGATCCCAATGTGGACATAGAAACTATGGAGCAGACAGATGAAAATACTGATGATGAAGTCGGATCTGTTTCAGTCTCTGACGCTGACACAGCAGGAGAAACCCCCAACTTGGGCTCTGTCATAGCCAACGACAGCGCCCTACTGGGAAAAATACTCAAAGTTggcaatgacaatgaaattCTAGTCTGTCATTATTGCGAACTAGACTTCAGTCGTCCCTCCTCTCTGCGCAAGCACATTCCCATTCATGAGGATCTTATGTACATGTGCCGCACTTGTGGCCTCACCTGGTCCAGTCAACAAAAACTCCACCTACACGAACAGGAAAAGGACCACACCAGCGAGCCCAACAAAAACCCTCAAGCCCTAGATTTTCGCTGTCTCCAATGCGGCAAGGTCTACGATCGATATTTCTGTATACTCCGTCACCAGCGAGAAGTCCATCGTCCTCTAGACCAACACTATCGCTGTGCCGAATGCAATGAAACCTTCAAATACCAAGCCATCTACGAGAAGCACCTGGAGAAACATCAGAACCACGACCAGCCAAAAATCCTGCCTTTCAGCTGCACCGAGTGCGACAAAGCCTTTGCCCGGCACTATCAACTGGTCACCCACAGTCGCATACACACCGGCGAGAAGCCCTACAAGTGTGAGGAGTGTGGCAAGCTCTTTGCCAATCGCTGCAATCGAACGCTCCACCAACGAACCCTACACGGGGGCGAGCGACGTTTCGAGTGCGACATCTGCCTGGCCCGCTTCACCACCAGCACCCACATGAAGAAACATCGCCAGCAACAGCACGGACTACCCGaaaaacatacaaacaaaagaattaaatataaataa
- Protein Sequence
- MSKELCKLCLENPAGSELLKTKGFMSAANLLERLFEAYEIECSYEDSVCQCCLADVLGICDSLCNWQKAQQLRTTTTIIDEELEQEISLIIQNDETEDQLDDPNVDIETMEQTDENTDDEVGSVSVSDADTAGETPNLGSVIANDSALLGKILKVGNDNEILVCHYCELDFSRPSSLRKHIPIHEDLMYMCRTCGLTWSSQQKLHLHEQEKDHTSEPNKNPQALDFRCLQCGKVYDRYFCILRHQREVHRPLDQHYRCAECNETFKYQAIYEKHLEKHQNHDQPKILPFSCTECDKAFARHYQLVTHSRIHTGEKPYKCEECGKLFANRCNRTLHQRTLHGGERRFECDICLARFTTSTHMKKHRQQQHGLPEKHTNKRIKYK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -