Slat000997.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Scaptodrosophila latifasciaeformis
Gene Symbol
RREB1_1
Assembly
GCA_037075145.1
Location
JBAMCM010000073.1:5882355-5888771[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00055 0.046 14.4 0.7 1 21 251 271 251 273 0.96
2 12 0.00032 0.027 15.1 0.2 1 23 283 305 283 305 0.98
3 12 2.2e-05 0.0019 18.8 7.5 1 23 311 333 311 333 0.98
4 12 0.22 18 6.2 1.0 2 19 551 568 551 568 0.97
5 12 0.036 3.1 8.7 0.1 1 23 727 749 727 749 0.97
6 12 9.8e-05 0.0083 16.7 1.4 1 23 759 781 759 781 0.99
7 12 0.00058 0.049 14.3 2.2 1 23 787 810 787 810 0.97
8 12 0.0028 0.24 12.2 2.0 1 23 1114 1137 1114 1137 0.95
9 12 8.1e-05 0.0069 17.0 0.3 2 23 1493 1514 1492 1514 0.97
10 12 0.14 12 6.8 6.3 1 23 1520 1543 1520 1543 0.97
11 12 0.079 6.7 7.6 1.1 3 23 1750 1770 1749 1770 0.91
12 12 0.0013 0.11 13.2 4.8 1 23 1776 1798 1776 1798 0.99

Sequence Information

Coding Sequence
ATGCTGGCATCGCAACAAAAGACAACGACATCGGCtttaccaccaccaccaccaatagcagcagagccaacaacaacaacaacacaaacaaatcttGAAAATGCCATTAAAATGGAGCGTCGCGATTCGAGCACATCCGAATCCTCGCTAGAGCATCTGGATCTGGGCCGTACACCAAAGAAGCTAACCACCACCAGCGGTAATCCCCAGCCAACCTCCACCCCGCATACCAATGGCACCGCCAGCGGCGCCGAGCTCAACAATACAACCAGCCCAAACACACTGACCCGCAAGCGTAAGCATCGCCAGCATCTGGATCAGCAGTCTCAGGCCGAACACCTGTACTCCGACAGGGATGAGTCAGCTCTGGCCGGCCAGAATGAGAGGGCACCGCGTCACAAGCAGAGACGCGTGAGCGGACGCCCGGTCACGGCCAGCATTGTGGGCGGTGATTCCAGTTCCTTGCGCAAAAAGTTTCGTCTCAAtcgcagtggtggtggtgctggcaaCGGCGGTGGGGAGCTGGGTGAGTCTGGCTTTGTGGATGGCAGTGGACATAGTAGCTATTTGCTGAATACCTCGGCTGCAGCGGTAGCGGCGTCGGCGGGCATGAGAAGTGTGGACACTGGTTTGGGTCTGTCGTCACGTGCCAGCAGTCACAGCAGTGGTCATAATTCGGGCTCATCTTCGCCGCAGGGCGGGCATTCGAGTGCCGAGTCTAGCATCTGGGCTGGTGATGAGTCGAGGAAATATGTCTGCCCCATTTGTGATGAGGTCTCGGCCACACCCCATGAGTTTACCAATCATATACGCTGCCACAATTATGCCTCAGGCGATACCGAGAATTTCACTTGTCGCATTTGCTCAAAGGTCTTGTCTTCAGCCTCTTCGCTGGATCGTCATGTCCTTGTCCATACCGGAGAGCGTccatttaattgcaaatattgCCATCTGACCTTCACCACAAATGGCAATATGCATCGTCATATGCGCACCCACAAGGAGCACCAACAGCAGCCCCAAAGACGACACTCGCAGAGCGCCAAAAATTCCGTATCAGCCGAATTGGCTGGCCAACGTTTGAATGGCGGTGGTCCCGGATTGACCAGTGCCCCAGTTAGTGTGACCGGCGGTGCCGGTGAGAGTTATGAGAGTGATGCCAGCTGCTCCACCGACTTGTCGAGTGGACAGAGTcagcacagcaacaacaacaacaacaacagccacaaaacGAACAACAATAATATGGAAGATCTTAAAGAGACAACAGGTGTATTGATGCTGGTGAAGCAGCCACGCCTCAAGACCACAATCAATAACAATATCATCAATGCCGAAGAGGAtgaggaggaagaggaggcGGCGGCAGAGGCAGAGAATGCCGCTGAGGACTTGGAGGAAGATGAAGAGGAGGCAGATGCCGAGACAAGCAAGGCATTGCTAGTGTCCAGTCCTCTCACCTCACCCTCCCACGAAGCCATTACCAGTACACCAGATGTGGCCACATTGCTGGCCAGTGCCTCGTCCACAGCCTCGGCCTCAGTGTCGCCGGGTCTCGGTCTCAACTGTCCAGCCTGTCCAGCCGCAGACTTTGAGAATCTACCCTCGCTATATGCCCACTTAGATGCCGAGCATGGTGACATACCGGCCAAGTGCCGCGACTGCGAGGTGGTCTTTCGCACACACCGACAAATGCAGACCCATCCCTGTACACAGAGATCTGGTCATTCGGTAGGCGAATTGCCGCCACTCTTGGCCACCAGCTCATCGCCTCTGCCCGAACCCGATATGGAAGATGACGAAGACGAGGATCCCGAAGCCGAAGCTGATGCCGATCTCGAGCAACGCGAACTTTTCTTTCGTCAGCTTCTGCTCAAGAACAAAGCTTCAGCTAACGCCAACGCAACCAAGGAAGCAAATCCACCAATGCTCTCGCCCATTTATGACAATCCACCCGATGCCTATGCCCAGGTCAAACTGGAGACAGACACCAAAGATCTAGCAGATATCCAATCCATACTAAACATGACCTCCTCCTCGTCCACCTCGAATTTCTTGCGCAACTTCGAGCAGACCGTCAACACTCCCTCCAGTCAGTACAGTCTCGACGGCAAGGACGAGGAAGAGGCCCAAGATGCCTTCACCTCCGAGTTTCGTAAAATGAAGATGCGCGGTGAATTCCCCTGCAAGCTCTGCGTAGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGTCACAATCGTATCCACCTGAGCGCCGTCGGTTCCAACGGACCCTTTCGCTGCAACATGTGCACCTATGCGATCTGCGACAAGGCAGCCCTGGTCCGTCACATGCGCACCCACAATGGTGATCGTCCGTATGAGTGCGCCGAATGCAATTACGCCTTCACCACCAAGGCCAATTGTGAGCGGCATTTGCGTAATCGTCATGGCAAGACCACCAGGGATGAGGTAAAACGTTCGATTGTCTATCATCCGGCCGAGGATGCCTCCTGCGATGAGGGTGGCTCGTCCAAATCCCTTTCCCGTCTCCAGCAAATGTATGCGGATGGCGGTGATCTCGACCTGGCCGAGCTGAGCTATCGTTCGAGTAGTCCCACACCACAGCCAGCGCCGCCGCCGCTAGCTTCGTCATCTTCGTCGTCAGCGGCTGTGGATACCCAACGAGTCACACCTGTGTCCCAGCTCAAGAACATGCTCCTAGCCGAGGGTCAATcccaaaagcagcagcaacaacagcagccgccACTCAAAATCCAAGTCAAAAGTCTCGATCAATTGGTCGAGAAGACCCAACAAACCGAGGCGGTCAGCACACCCAACTCAGCCAAGCCCATGGACCTAACCATGGATGTCTTGGATCTGAGCAAGAAGCCCTCAGCCCCAGCCACCCAAGCCATGTTGCCACCAGAGCTCGACTTGGCTGCCGTTCtcgagcagcagcaacagcaacagctccTCCTAGCCCAGCAGCAGTTCTTTACCAACGCAGATCCGTATGTCCAAATCCTGAGACAGTTCATGTTACAGCAATCCTTATTTAACTTTATGCCGCCCACCAATCCGGCTGAAGCTCTTATGACACGGATGTACAAGATGCCGGGAGCAGGTGGAGTGGGTGGAACACCTGCAGCTGGCGTAGAGAAATCAAGTTCGCCTACTCTCTTGCCACAGATTAGCCCGCTGATGGCCGGTTCGGAGAAGACCCCTTTAATGCCAGCCCGGACTGTGGGTACGTCCAATCTGGCGCCTCTGCCTGGTGGACCCGTCAAAATGGTGATCAAAAATGGTGTGCTCATGCCCAAACAGAAGCAGCGTCGCTATCGTACCGAACGTCCCTTTGCCTGCGAGCATTGCTCGGCTCGCTTCACCCTACGCTCCAACATGGAGCGTCATGTGAAACAACAGCATCCCCAGTTCTATGCCCAGCGCCAGCGTAGTGGTCATCATGTGATGCGTGGACGTGGTGCCATGGGTCTGAGTTCTATGGGACGTCTGCAGGCGGCAGTTGGTGCCGGATTCGGTGTGCCCCAATCGGCACATTCCAAtggcagcggtggcagcagcaacagtggcATCTCACCCATTTCGGAGCAGGTGAAATATGCCATTTTGGCCCAGCAATTGAAGGCTCACAAGGACACGGATCTGCTGCAGCAGGCTCTGGCCCATGGCTCGAGCAGTGTGGCGGGTGCCAACTCCCTGCTTAACTTTGGCTATAATCAGCTAAATGGTGGTGGCCCAAATGTCCAGACCAATGGTACCCTCGACGATGATGAACCCAAGCTGATCATAGACGAAGATGATCAGGTCTTGGATGAAGATCCCGAAGAGGACGAGGAAGACGAGGAGGATGAGGAAGACCTGATGGACTCGAAGCCAGAAGTTGAAGATGAGCTGGTAGCGGAAACCGATAAGCCAGAACCAACACCACCAGCTGCTGATCCCAAGAAATTGCCCGAAGCCATTGAAGAATTGGCCAGAACCAAGCTCACACCACCCTCCATGGAGACGGCCAAAAAATTAGCCAACACCATCTTGGAGCAGGCCATCAAGGCTGCTTCCCCAACTGCcacagctgctgctgcccttGCTCCTGCCTCCGGGGAAATCCAGGCCCCGCCCACACCGATACCCACCGCCCCCACACCAGCACACACCATGAAATCAATGATTGCTCAGGTCGAGTCTGTGGCCAAGTCCCTCAAGGAGGTGGCCAGTTCGCGTTTCAAAGATGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTCGTCGACAATGCCACCAGCAATCAGGTCTCCTTCAACACATATTTCCGACCCAGCGACGTGGCCAATCACATGGAGCAGAGCGACGAAGAGGGTCTCGTTGCCTCCGGCAGTGCCAGTGAGAGCAACAATTCCGGCACCGAAGATgtcaccaccagcaccaccgaGCCCAAAAAGAAATCTGCCTACAGCCTGGCCCCCAATCGGGTATCCTGTCCCTATTGCCAGCGCATGTTCCCCTGGTCCAGTTCCTTGCGTCGCCACATTCTCACCCACACTGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTCCTCTTTACCACGAAAAGCAACTGCGATCGCCATCTCCTGCGCAAGCATGGCAATGTCGAATCCGCCATGTCCGTCTATGTGCCCACCGAGGACGTCAACGAGCCCATTCCAGTGCCCAAGTCTGTGGAGGAAATCgaacagcagcagcgccaGCGTGAAGAGGAAGAACGCCGCCGTAAGGCCGCCGCAGCCGAGGCCGAGCAAGAGGAACGCGCCCAGCTGGAGGCCCAGCGTCAGCGGGAACgcgagcagcaacaacaggagcAACTCCTCGAGCAGTTGGCCGTAGCCAATCAGATCAACCAGCGCATCAATGCGGCCGTTGTGGCAGCGGCTGCGGCCaatgccagtgccagtgccagcgCCCTCGAGGCCAGCGCCGGGGCCAACTCGGATCTGCCCTACAAGTGCCATCTGTGCGAGTGCTCCTTTGGGGAGCGTCTGCAGTGCCTGGATCATATCAAGCAACAGCATGGCCAGGAGTTTGCCCTGCTGCTGGCCAAGGGTGCCATTGAGACGGATGTCCTGGAGCCACCACTACCGCCACCCCTCAGCCTTGCCGGCTCAGATGAGGAGCAAGGCGGAGGCGTCGGTGGTCTGGGCAATGCCAATGGCTCACGCGGAGCCAGTGGCAAATATCCGGACTATAGCAACCGCAAGGTGATTTGCGCCTTTTGCATGCGTCGCTTCTGGTCCACCGAGGATCTGAGGCGCCATATGCGCACCCATTCGGGTGAGCGGCCCTTTCAGTGCGAGATTTGCCTGCGCAAGTTCACCCTGAAGCACAGCATGCTGCGTCACATGAAGAAGCACAGTGGCCGCCCCTACAATGGCACCAATGGGGCTGGCTCCGAGCATGGCGGCTCGGATTGCTCCGATGATGAGCAATCCtccacaccaccaccaccgccaccaccacttCCGCCGCCACCAGCCTCGAATGGCACTAGctcacacaacaacaacaacaacaataataacaacaacaataacaacaaattgagCATGCGTCCACCCAAGCTACACGAGCTGCTGGACAAGACGAGCGAATGGCGCGCCAGCCACCTGGGCGAGCACAAGGAGAATCTGGGCGAAATGGCCTCACCctcggcggcagcagcagcagcagtcagcGCTGGCAGCGATCTCATTGGCAATCTCCTCGGCATCAATGACCAAGGCATACTCAACAAGCTGCTCTCCTCCGCCGAAGAAGCCGCCAAATTTTTGGGCGTCGACAACAAGTAA
Protein Sequence
MLASQQKTTTSALPPPPPIAAEPTTTTTQTNLENAIKMERRDSSTSESSLEHLDLGRTPKKLTTTSGNPQPTSTPHTNGTASGAELNNTTSPNTLTRKRKHRQHLDQQSQAEHLYSDRDESALAGQNERAPRHKQRRVSGRPVTASIVGGDSSSLRKKFRLNRSGGGAGNGGGELGESGFVDGSGHSSYLLNTSAAAVAASAGMRSVDTGLGLSSRASSHSSGHNSGSSSPQGGHSSAESSIWAGDESRKYVCPICDEVSATPHEFTNHIRCHNYASGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCKYCHLTFTTNGNMHRHMRTHKEHQQQPQRRHSQSAKNSVSAELAGQRLNGGGPGLTSAPVSVTGGAGESYESDASCSTDLSSGQSQHSNNNNNNSHKTNNNNMEDLKETTGVLMLVKQPRLKTTINNNIINAEEDEEEEEAAAEAENAAEDLEEDEEEADAETSKALLVSSPLTSPSHEAITSTPDVATLLASASSTASASVSPGLGLNCPACPAADFENLPSLYAHLDAEHGDIPAKCRDCEVVFRTHRQMQTHPCTQRSGHSVGELPPLLATSSSPLPEPDMEDDEDEDPEAEADADLEQRELFFRQLLLKNKASANANATKEANPPMLSPIYDNPPDAYAQVKLETDTKDLADIQSILNMTSSSSTSNFLRNFEQTVNTPSSQYSLDGKDEEEAQDAFTSEFRKMKMRGEFPCKLCVAVFPNLRALKGHNRIHLSAVGSNGPFRCNMCTYAICDKAALVRHMRTHNGDRPYECAECNYAFTTKANCERHLRNRHGKTTRDEVKRSIVYHPAEDASCDEGGSSKSLSRLQQMYADGGDLDLAELSYRSSSPTPQPAPPPLASSSSSSAAVDTQRVTPVSQLKNMLLAEGQSQKQQQQQQPPLKIQVKSLDQLVEKTQQTEAVSTPNSAKPMDLTMDVLDLSKKPSAPATQAMLPPELDLAAVLEQQQQQQLLLAQQQFFTNADPYVQILRQFMLQQSLFNFMPPTNPAEALMTRMYKMPGAGGVGGTPAAGVEKSSSPTLLPQISPLMAGSEKTPLMPARTVGTSNLAPLPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGAMGLSSMGRLQAAVGAGFGVPQSAHSNGSGGSSNSGISPISEQVKYAILAQQLKAHKDTDLLQQALAHGSSSVAGANSLLNFGYNQLNGGGPNVQTNGTLDDDEPKLIIDEDDQVLDEDPEEDEEDEEDEEDLMDSKPEVEDELVAETDKPEPTPPAADPKKLPEAIEELARTKLTPPSMETAKKLANTILEQAIKAASPTATAAAALAPASGEIQAPPTPIPTAPTPAHTMKSMIAQVESVAKSLKEVASSRFKDESQDLVPVAKLVDNATSNQVSFNTYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTTSTTEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVNEPIPVPKSVEEIEQQQRQREEEERRRKAAAAEAEQEERAQLEAQRQREREQQQQEQLLEQLAVANQINQRINAAVVAAAAANASASASALEASAGANSDLPYKCHLCECSFGERLQCLDHIKQQHGQEFALLLAKGAIETDVLEPPLPPPLSLAGSDEEQGGGVGGLGNANGSRGASGKYPDYSNRKVICAFCMRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRPYNGTNGAGSEHGGSDCSDDEQSSTPPPPPPPLPPPPASNGTSSHNNNNNNNNNNNNNKLSMRPPKLHELLDKTSEWRASHLGEHKENLGEMASPSAAAAAAVSAGSDLIGNLLGINDQGILNKLLSSAEEAAKFLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-