Slat002259.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_037075145.1
- Location
- JBAMCM010000100.1:9159426-9162021[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.088 7.5 7.4 1.6 2 20 211 229 210 232 0.93 2 13 0.17 14 6.6 2.7 1 23 322 347 322 347 0.97 3 13 0.095 8.1 7.3 0.1 1 21 354 374 354 375 0.92 4 13 0.00031 0.026 15.2 0.6 2 23 414 436 413 436 0.96 5 13 0.00041 0.035 14.8 1.4 5 23 447 465 444 465 0.93 6 13 0.0035 0.29 11.9 0.0 2 21 492 511 491 512 0.94 7 13 0.00026 0.022 15.4 1.4 1 23 557 580 557 580 0.96 8 13 0.014 1.2 10.0 0.1 2 23 618 640 617 640 0.96 9 13 0.00025 0.021 15.5 0.9 2 23 655 677 654 677 0.94 10 13 3.7e-06 0.00031 21.2 0.6 1 23 691 713 691 713 0.96 11 13 0.00015 0.013 16.1 0.3 1 23 719 741 719 741 0.99 12 13 0.00016 0.013 16.1 5.1 1 23 747 769 747 769 0.97 13 13 0.00061 0.051 14.2 6.4 1 23 775 797 775 797 0.98
Sequence Information
- Coding Sequence
- atgcaactgcCAATTTTTTGCCGCACATGCGATACCCgtgacttaaaaattttgcacgAACTTTCTGCACGTCCGCGAAAGTATGAGGCCAAAACTCTGGCCGACTTACTTGCAGAGCTAACTGATATCGAtATCAATGGGATTGCCACGGAACAAATGCCACAGTGTTTATGCAGCAACTGCACacggaaattgaaaaatgcctATGATTTTGTGCTACAAGCGAGAGCAGCCCACCATATCTtaatgcttaaaattaaaagcgatGAAGCTGAAGTAATAACAGATGGAATTTCAGGTGAACAACAACCAATCCAAGAAGTTTTTGATAATAGTAGCCTGCCTCAAAATGTCCCCGAAGATTGTGCAATCCAAACTGATGAAAACATAGAATCAATACCTGAGCTTCCTTTACAAGGACTTCCCAAGGAAACTGGCATTTCTTtagaaagtgaaaatgaagTACCTCTTAATTCAAACGTAGAGCAACAAACACTGGACTCTCAACATGAAAATCCAGAAGAATTACCTGAGACATCCATAGCAAGTCACGAGCCCCAGTTAAACCAACACAAGAGGGTCAAAAATATTGATCTTAACCTGTGTAAACCTAACGGCTTTAAGCTTATTCAGTGCATGATTTGTCAGgctcatttcaaaaaaatgtcCGAATTGCATAATCATTTACCGCAGCACAGAACCGATCTTGACCTTGATCATATGGCAGAAATTTGGAAGCTAAACCATACCGAGTTAAGGGAATTCTTCTATCCCGAGCTGAAGCTATTGAAGGAAAAGCAACTCAAAGAACGCATTTGCACAGATTTGGAAACTGAAAACTACTCACGTTTCTACTCCATAACCAATCAATGGGGCTATGAAATGGATCTGGATTCCACAGAGACCGAAAGCGAAATTGAAGAAGAGGATGATGGAAATAGACCAGCCCCgaatatctcaaaatattACTGCGAACTCTGTGGTAATCATCAAAGTTATCAACGAAAGTTTGAGCTCTATGAGCACCAGCGTCAAGAGCACTCCTGGTCTGAGGCTCCCCACATTTGTGGGCGCTGTGGTGCCCGCTTTATAAGCCTTTTGCTGTTGACTCAACACTACCTCTCCCAATGTAAGAACACCCAGAAACGTTACATATGCCGGCATTGTCCTATGCGCTTTCAATGGAGGCACAACTTTAAGGCCCACTGCCGGAATCACAAGACCAAGTCTTGCATTCTAGAATGTCCACATTGCGCCCGAAAATTTGATGGGCAAACATCACTGACTACTCACTTGCTTACCGCTCATGCAGACGAGTCAAAACTAATTCCCTGCATTTTCTGCAAAAGAAAGTTTTATCGTCAGGACAATTTGATCAATCACTTAAAGCGGCATAACATCAAGGAGCAGGACATGCCTTTAGCTCAAACCCTGATGGCTGCTACGAGCCAAGCGAATGGTCAAAAATGCATTAGCTGTGAGATTTGCAATCAAAAATTCCAACGAATCGCTGACTTGCGTGTCCACATTCAAGCACAGATTGAATTGGATGATTTCACTCACTCCGAATGCGACACTCTATGGAGCTACTCCATAACCAATGAAAGAGGCTTCGAAATGCATTTGGATGACTCGGAAACCGAAGATGAAAACGCTCTTAGCTACGAATATCTGTGTGACCTTTGTCAAGTCAGTTTCAAACGTAAATTTCAGATGATGCAACATCAGCAGACAGTCCATCCATTTGATAAAATTCCCTACCAATGTGGTCATTGCATATTCAAGAGTGTCTCCAAGaaaattctggAACATCATGAGAAAGTCCAGTGTTTGTGCCAGGCAAAACAGCTCGAGTGTTCCGaatgcaaatacaaattcatGTGGCCCTGGAACCTAGAGCAGCATCTAATAACTTATCATGCTGGTCAACAAAATTCTGAAGAATCTAAGGCCAAACTCCTGCCCTGTCCACACTGTGATAGAACCTATCAGTTGAAATCACGTCTCAACAACCACATCAGGGATATTCACATAAATGGCGATCGAAAGCGCTTGGAGTCTACTAAAAAGTTCCTGTGTTCTATTTGTGGCAAAGAGACCTCGTCCAAGGCCAGTCTCTTGACCCATATGCGACGTCACACTGGCGAGAAACCTTTCAAATGCAATTCATGTGAGATGGCCTTTCCAAGGTACGCCGAACTGGTCTATCATCAACGTGTTCATACGGGTGAAAAGCCCTTTCATTGCGCCATATGTGAAAAGGACTTTGCTCATGCTCACAAATTAAAGAGGCACATGCTAAGCCATAGCGATCTAAAGCCACACAAATGTGTCCACTGCGAAAAGAGctacaaacaaatcaaagatcTTAAGACTCATTTGAAAAGGCACACTGATGAGTctggcaaatga
- Protein Sequence
- MQLPIFCRTCDTRDLKILHELSARPRKYEAKTLADLLAELTDIDINGIATEQMPQCLCSNCTRKLKNAYDFVLQARAAHHILMLKIKSDEAEVITDGISGEQQPIQEVFDNSSLPQNVPEDCAIQTDENIESIPELPLQGLPKETGISLESENEVPLNSNVEQQTLDSQHENPEELPETSIASHEPQLNQHKRVKNIDLNLCKPNGFKLIQCMICQAHFKKMSELHNHLPQHRTDLDLDHMAEIWKLNHTELREFFYPELKLLKEKQLKERICTDLETENYSRFYSITNQWGYEMDLDSTETESEIEEEDDGNRPAPNISKYYCELCGNHQSYQRKFELYEHQRQEHSWSEAPHICGRCGARFISLLLLTQHYLSQCKNTQKRYICRHCPMRFQWRHNFKAHCRNHKTKSCILECPHCARKFDGQTSLTTHLLTAHADESKLIPCIFCKRKFYRQDNLINHLKRHNIKEQDMPLAQTLMAATSQANGQKCISCEICNQKFQRIADLRVHIQAQIELDDFTHSECDTLWSYSITNERGFEMHLDDSETEDENALSYEYLCDLCQVSFKRKFQMMQHQQTVHPFDKIPYQCGHCIFKSVSKKILEHHEKVQCLCQAKQLECSECKYKFMWPWNLEQHLITYHAGQQNSEESKAKLLPCPHCDRTYQLKSRLNNHIRDIHINGDRKRLESTKKFLCSICGKETSSKASLLTHMRRHTGEKPFKCNSCEMAFPRYAELVYHQRVHTGEKPFHCAICEKDFAHAHKLKRHMLSHSDLKPHKCVHCEKSYKQIKDLKTHLKRHTDESGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -