Basic Information

Insect: Scaptodrosophila latifasciaeformis
Gene Symbol: zfh1_3
Assembly: GCA_037075145.1
Location: JBAMCM010000100.1:18415145-18444265[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0038 0.32 11.7 3.6 2 23 80 102 79 102 0.95

2 9 0.0024 0.21 12.3 0.1 1 23 304 326 304 326 0.96

3 9 3e-05 0.0026 18.3 1.8 2 23 340 361 339 361 0.97

4 9 1.6e-05 0.0013 19.3 6.4 1 23 370 392 370 392 0.99

5 9 0.00031 0.026 15.1 1.2 3 21 400 418 398 419 0.94

6 9 0.0017 0.15 12.8 0.5 2 21 661 680 660 681 0.92

7 9 4.9e-05 0.0041 17.7 0.5 1 23 1052 1074 1052 1074 0.94

8 9 5.2e-05 0.0044 17.6 7.4 1 23 1080 1102 1080 1102 0.98

9 9 0.0026 0.22 12.2 4.3 1 21 1108 1128 1108 1129 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0038	0.32	11.7	3.6	2	23	80	102	79	102	0.95
2	9	0.0024	0.21	12.3	0.1	1	23	304	326	304	326	0.96
3	9	3e-05	0.0026	18.3	1.8	2	23	340	361	339	361	0.97
4	9	1.6e-05	0.0013	19.3	6.4	1	23	370	392	370	392	0.99
5	9	0.00031	0.026	15.1	1.2	3	21	400	418	398	419	0.94
6	9	0.0017	0.15	12.8	0.5	2	21	661	680	660	681	0.92
7	9	4.9e-05	0.0041	17.7	0.5	1	23	1052	1074	1052	1074	0.94
8	9	5.2e-05	0.0044	17.6	7.4	1	23	1080	1102	1080	1102	0.98
9	9	0.0026	0.22	12.2	4.3	1	21	1108	1128	1108	1129	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCGTCGTCTTCACGTTTTGGCCAAGAGGATAACATTATTCAGCAAAGTATGCCATCATCCACAGCCTTCTCCATGCAGTTTCCCTCCTTGGCCTCCAGTCTGCACCACCATCAAGTGCTGAGCAAGGCAAGCAATGCCGCCAGTCCAGAGCAGGAAGAACTGGAACATCATGCAGCCGGAGCCACAGCTATGGTGGGCTGTGCCGATGACTACCTGATCAAGTGCCATCAGTGCCACAAGCGTTTCACAGAGTTTCAGTCTCTCAGCGAGCATATAGCCAGTGAGCATCCCTTGGATAAGCTAAATTTCGACTCAGCCCGAGCCGCCAGTGCCATGGGCGCCACACAGCCGGAAAGTGATGCCGACGAGGCTGATCCCATGGACGAGGGCGAGCAGagcaatagcagcagcagtcgcAAATACACCAAGTCTCCGGCCCACTCGGCCAGCCactccagcaacaacaacaacaatgagacgACAAagaatcacaacaacaataacaacaacaacagtcacagtcacagtcacCACAGTATTAACAAGCACTCACCCATGTGCTCACCCAGTGGAGCCGCAGCTTCATCAGCCCCAGCAGATGTCTTTACCTCCGGCCCCTTGCCCCCGCACATTCAGGCCCAATTTATGGCCGCCGCCCTGGCCATGCAAACGGGCCGCTCGGCACGCTCGGCTGTCTCACCGAACTATTCGCTTTTACCGCCAGCccatcaccaccagcaccTTCCACATCCACATCCGCACCAGCCACAGCATCTGCTCAATggcggcagcaacagcagcgtGGGCAGCAATTCCGCCTACGACCTGGACCTGACCACGGCCCGATCCACCTCCAGTCCCGGCTCCACCACGGGTGATCTCAGTGGCACATACCCCTGCATGCAATGCACGGCGGCTTTTGCCACACGCGACCAACTGGAGCAACACGAACTGCTGCACTCACCGAGCGGCCAGCCCAGCACCCAAAATGTCACCCAGACTTGCAAAATATGCCACAAAGCCTTCGCCAATGTGTACCGCCTCCAACGGCACATGATCAGCCACGATGAGTCCGCTCTGCTCCGGAAATTCAAATGCAGCCAATGCGACAAGGCCTTCAAATTCAAGCACCACCTCAAGGAGCATGTCCGGATCCACTCGGGCGAGAAGCCCTTTGGCTGTGACAACTGCGGCAAGAGATTCTCGCACTCGGGCTCCTTCTCCTCCCACATGACCTCCAAGAAGTGCATCAGCATGGGTCTCAAGCTGAACAATAATCGAGCCATGCTCAAGTCCCTGGACAAGAGCGGTCCGGCTGGCAATGGGCGCTCGGCCTCCGACCAGCAGACAGCGGGCAAGCGGTCCAACAAAATGCCAGAGCCCCAGGCACCCCAGGCGGGTTTGCCCCTGCCGGCTCTGCCGCCTGCATTGCCCAATCCCATGAACTATTTTGCCGGCGATGCCCAGGCCAATGGCGGACCCAGTCAAATCTACAGTGCCATGAATGCCCTGATGAGCGTCTTCCCAAATGCCTTCTATAGCATGGCTCCCGATCCTCGGATGCCACCCTACAATATCCAGCGGCTGTTGGagttgcagcagcagcagcagcagtcggTGGCAGCGGCCGCAGCCTTGTATGATGAAATGAAGGAGAATGTGAAGCATGAAGAGGACCTGCCGGATGAGCCCAAACTGGTGATGGACTTGGAAGACTCCGAGGCCAAGGAGCCTGTCAAGACACCCAAGCCTGCTACACCGAAGGCAGAGGAAGAACCCCTGGACGAGGCCCCTGTTAAGCAGGAGCCCAGTCGAGAACCCACGCCCGTAGCCATCAACCTGGAGAGCAATCCAGCCACACCCAAGTCCATTAAGGTGGAGCAAGAAGAGCCCGTCGAGCTGTCCGTCTCACCGGCGGCTGCTCGACCCCAAACACCCCTCGAGCCTGTCAATCCCGAGCTGCGGTGCAGCCGTTGCGACAAGCAATTCAACCATCCCACAGAGCTGGTCCAGCACGAGAAGGTACTCTGTGGCCTAATCAAAGACGAACTGGAACAACATTACCAACAGGCCCAGCACCGCCTACATGAAGATGCCCAGGGCTCCAGCTTCCTCCTGCGCTCGGCTAGCGAAGCCGACGAGGAGGAAGAGCATCCCGAGGGCGATGAAGATCGCCAGGAGCTCGAGAGCCGCCACGACTACAACGGCAATGGCAGCGACAGCGGGGAGCGCAAGGTCCGTGTGCGCACCGCCATCAAcgaggagcagcagcagcagctgaagcaGCACTACGCCCACAATGCCCGTCCTAGTCGGGATGAATTCCGTCTCATAGCCGGCCGTCTCCAGCTAGATCCTCGAGTGGTTCAGGTCTGGTTCCAAAACAATCGCTCCAGGGAGCGCAAGCTCCAGAGCTATGCCGTGGCCGCAGCTGCCAGCACCAGCGAAGCCCTGCCAGCCTCTGCACCCAGATCTGGCGAGGATCAGCCTCTGGATCTGTCGGTCAAACGGGATTCACTGACACCGCAACGAAACTCACCCTTGTACGGTGTGGCTCCCCAGCAGGCCAACAGTGCCGGGCCCAACGACTTTCAGGAGGCCATGAATCTAAGCCGCAAACTCTCCACTTCGGCCTCGCTCTCACCGGCCTCAGTGTCACCCTCGTCGGGCGCCTCAGTGCCCCAGGCCTTCAAGCAGCAAGCCTTCTATTTGGGGGGCGCCCCGCCACCACATCATCCACGCCAGACGCCCTCTCCACCCCAACTGCTTGAGACCACACCCACCACAGCCGTGCTCCCGCAGCACAGCTCCACCCCACGCAGTGGACCCAACAATGCCTTCCTCAGTCTGGCCAGCCATCTTCCACCCTACCTGCTGCCCGGTAGCATGCATCGCGGCCTGGTGCCCATGGAGTCCCTCTTCCAGATGACGGCCAGCGAATACGGACGCAATCCTCTCATGAACAGTATTAAGCTGCCCGACTACCGCGGCACCAGCCTCAGCCCTGGCGGCTCCGAGAAGCGTTCCTGGCGCGACGACGACTCCCGCGAAGACGACTACGGCGGTCTGCACATTTCCAAGCCCAAACGGGCCAAGGCCGAGACCCACGGCCATGCCGGCGATCCCGATCTGCCCTTCGTCTGCGATCAATGCGAAAAGGCCTTCGCCAAGCAGAGCTCCCTGGCCCGCCACAAATACGAGCATTCCGGTCAACGGCCCTACCAGTGCATGGACTGCCCCAAGGCCTTCAAGCACAAACACCACCTGACGGAGCACAAGCGCCTGCACAGCGGCGAGAAGCCCTTTCAGTGCTCCAAGTGCCTGAAGCGTTTCTCCCACTCGGGCAGCTACTCCCAGCACATGAACCACCGTTACTCCTACTGCAAACCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSSRFGQEDNIIQQSMPSSTAFSMQFPSLASSLHHHQVLSKASNAASPEQEELEHHAAGATAMVGCADDYLIKCHQCHKRFTEFQSLSEHIASEHPLDKLNFDSARAASAMGATQPESDADEADPMDEGEQSNSSSSRKYTKSPAHSASHSSNNNNNETTKNHNNNNNNNSHSHSHHSINKHSPMCSPSGAAASSAPADVFTSGPLPPHIQAQFMAAALAMQTGRSARSAVSPNYSLLPPAHHHQHLPHPHPHQPQHLLNGGSNSSVGSNSAYDLDLTTARSTSSPGSTTGDLSGTYPCMQCTAAFATRDQLEQHELLHSPSGQPSTQNVTQTCKICHKAFANVYRLQRHMISHDESALLRKFKCSQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRAMLKSLDKSGPAGNGRSASDQQTAGKRSNKMPEPQAPQAGLPLPALPPALPNPMNYFAGDAQANGGPSQIYSAMNALMSVFPNAFYSMAPDPRMPPYNIQRLLELQQQQQQSVAAAAALYDEMKENVKHEEDLPDEPKLVMDLEDSEAKEPVKTPKPATPKAEEEPLDEAPVKQEPSREPTPVAINLESNPATPKSIKVEQEEPVELSVSPAAARPQTPLEPVNPELRCSRCDKQFNHPTELVQHEKVLCGLIKDELEQHYQQAQHRLHEDAQGSSFLLRSASEADEEEEHPEGDEDRQELESRHDYNGNGSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDEFRLIAGRLQLDPRVVQVWFQNNRSRERKLQSYAVAAAASTSEALPASAPRSGEDQPLDLSVKRDSLTPQRNSPLYGVAPQQANSAGPNDFQEAMNLSRKLSTSASLSPASVSPSSGASVPQAFKQQAFYLGGAPPPHHPRQTPSPPQLLETTPTTAVLPQHSSTPRSGPNNAFLSLASHLPPYLLPGSMHRGLVPMESLFQMTASEYGRNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSREDDYGGLHISKPKRAKAETHGHAGDPDLPFVCDQCEKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01318932;
90% Identity: iTF_01318932;
80% Identity: iTF_01318932;