Slat003896.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_037075145.1
- Location
- JBAMCM010000100.1:23521281-23527610[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0049 0.41 11.4 0.5 1 23 1482 1505 1482 1505 0.97 2 13 8.1 6.9e+02 1.3 0.2 1 23 1679 1701 1679 1701 0.91 3 13 0.00018 0.015 15.9 2.7 2 23 1704 1725 1704 1725 0.97 4 13 7e-05 0.0059 17.2 0.2 3 23 1733 1753 1731 1753 0.98 5 13 5.8e-07 4.9e-05 23.7 4.1 2 23 1760 1781 1759 1781 0.97 6 13 5.5 4.6e+02 1.8 0.4 5 23 1794 1812 1792 1812 0.96 7 13 1.4 1.2e+02 3.7 5.4 3 23 1819 1840 1817 1840 0.93 8 13 0.075 6.4 7.7 0.1 2 23 1851 1871 1850 1871 0.96 9 13 5.6e-05 0.0047 17.5 0.4 1 19 1877 1895 1877 1899 0.95 10 13 9.7e-05 0.0082 16.7 1.3 1 23 1907 1929 1907 1929 0.97 11 13 0.0001 0.0088 16.6 7.6 1 23 1935 1957 1935 1958 0.96 12 13 0.0002 0.017 15.7 5.9 1 23 1963 1985 1963 1985 0.98 13 13 0.0017 0.14 12.8 6.0 1 23 1991 2013 1991 2014 0.96
Sequence Information
- Coding Sequence
- ATGGTCGAAAGTGTGCAGTGCCCCGTGTGCACTCTGTATTTGCATGCGGGCATGAATCTCTCGGATCACTTGGATACACATCCCAAAGAGCAGGTTATCAAGGCTCTTGTGCAAATGACAATCGCGGGCAATGGGCCGGCCAATGCTCTGGCAGCTGTCCTGGCCAGCAGTGGCTCAGATGATACGGCGGCCAGCGCTGGCAGTGGGGCTGATGTGAAGCCACTTGGGGACACCAGTAGCCTGTCCAAGTTGGTCAGCGCCATAGTCACTGctactgccaccgccaccaccaacacaTCTGCATCAGCAACGTCCTCTTCAACCGTGACTGCTGGCCTGGAACCCGCTGAGTTTGTAgccagcagcagtagcagcagcaagcCCCACAGTGGCAATTGCCACACcaacaataaattgaataatccaccgactaaacaaaaatatgaggGACTGAAAATCACAATGCCAAACCAGCCAAATCCAAGGTTGACAGCCGGCGAGGCCACatccacactcacacccaccaccaccaccaccgccagcgCCGCTACCGCCGCCACCAGCAATTATCAGCAGCAACCCCAACAGGCGCTGAGTCTGCCAGCCGGCGAATTCCGTTACGAACAACAGGCAACGCCTCACTTTCAACATACCAATCGTACAACCGTGGCGGCAACACCAGCCCTGGCCTACAGTGCGAGTGGCTTGCATCCAGCAACACCCCAGCCTCAtccacagcaacagcatcagcacTATGTGACCACCACCCAGCAGCTGCAGCGTCATGGGCCACAACAGCACCCGCCGCACTCTCTGCATCAGCCCACACACTTTGCCACACATCAGCAGAGTCTGAAGTATTATACCACCAACCTGcctccgccgccgccgctaCAGCTCTTTGGCCAATTGCCGACGACCTCGCAGTCGGCTCAGCATCAGAAGCCACCGCCCGCTTACGGGGCCGCCATCAGTCAAATTCGATCTCAGcacaaccaaaataaacaacaacaccaacaacatcatccacaacaacaacaacaacagcagcagcaacagcagcatcatcaccaccagcaacagccGCAGCCGCCACAAACCCTTACCAGCATAACCATACACCAAATCCAACCACCGACAGCTGATGCCGTAGCTGTAGCTGCCGCCGCTGCAGCTGCTTCAAtggccacaaaacaaaataataaaaccactGCAGCCGCCCATACGGATATCTTTTTTAATCTCCCACCACCACCGAACCCAGCGCCAGTGGCCAACGCCAGCACTACCGGCGCCGCAACCGCAGTAACTTCTGCTTTGCCTACGTCATCAGGGTCCAACACTAGAATGCCCACGCCCACACCGGCCCATCTAGCACATTTGCCGCATCAGCCCTATGCGGCAGCTTCCCATCTGCCTGTGACGGCCCCACAAAACCCTAGCGGGAATAATAGACCAAGCCAGGTCTCGCCGGCCCGTTCAGCCGCGTCCAGTGCTCGTCAAACCAATTCACCCTTCGGAGCTTTGCTaaccgctgctgctgccgccgtcTGTGCGTCGCCCTCATCGGTTCTGCGCTATGCCGAGTCGCCGGTGGCCCACTATCTGGAACGAGAGAACGGTGACTTTATTGTCCAGGAGACGCCCAAGCATATTGTGGAGTGCGTGGAGAAGGAGGATGGTGAATTCTCGGTTATCGAACGCATTTATCAATCGCCACCAAGTGTGCTCCGTATccacgacgatgacgacgacgatgatgatgacgagaAGGAGGAGTCACACGATCCAGCAAGGCACAAGAAGCAAGAGAATGATGAGCGCCTAGCTGATGAAGGCGATTACGAGCGCGAAGATAGCCGCAGTCGACCATCAACCAGCAACTCCGCCGCCAACAAGAAACAACGTTCTTCCAAAATTACTAAAACCAAGGTCAACACTAAATTGGGCAAGTCTTCGCAAATACCCTTGAAACCCATACCAGACGACGTGGACATGATGAGCCTGAGCAGTGGCTCCGACAACGAGGAACCAACTCAACCGTTGGCCAACACTGCCAATCACCAGCCGCTCAGCCTGTCGGCctccaccagcaacagcaacacctTGACCCATTCGGCCACCACAGATGGTAATTCCAATTCCAATGCCAGTGGTGGCACCAAATCTAAGAAGAATCGTATAACCGTGCTCAGCGATGTTCCATTGAATATGAATGAATATTTGGATTTGGTGGGGAACATTGTGGCCTCAAGCCGGATAACTGCATCGCGACCCTTTGCCGCCATGGCTCCCCTACCGCTTGTGAAGGTTGAAAAGGAAGAGCCTCTGGATGATTATGATGCTGAGTCGATATCTGCTTTTTCCCATCAGACGCACACGCCCAGTGCGGAGATCGAGACTGAGGATGTAGAGCAAAAACCAAGTCTAGATGATCAGCTACATGTTCAGCAGGCAAGTGGCAGTGTGATGAGTGCTAACAATGGCGGTCATTGTACCACCAGTGTTATACGCATGGCCAGTGCCAATGCGCCGCCACCAACAGAGGATTTCACTCCGGAAGACTTGACACAGCCGCCCACTATGAAAATTGAGGTAGAGCCCACCGCTTTGATGCCCCAGAGATTTGCAGCGCCAGCCATACAGCAGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGtcaaccacaacagcaacggTGGCAgccacaaagacaaaaaagactgacattgccaccgccaccagcaccagcatcACCAGTCTAGAGCCCAAAGCCTCTACTTCGGCAGCGGCCCAAACCCTCAGCATATCACAGACCCTTATAGCCAATACCAGCGCCCTTGAGGTGGTCCATATCAAGAGTGAAGTCTGCGAACCGCCCAGCATTAGCATGGGCAGTATACTGGAGAAGCACCTTACCACCAATTACGGCTATCCAGGTCAGCAGTCCCAGCAGCGTCGCAAGATTTCCGCCgttaatgatgatgatgcccGGGTGTTGCTGGAGTTTGCCAATTCCAAGCAACCACCGGTGGATGGCTCAGCCAGCACCACCTTTGTGGTGAATGCAGCCACCTTCCCATCGGCCAATTCGGTATTTGCCAGCGGCAGCACAAACGCCACCAGCACTGCACACATGGgcacacaaaagaaagaggaatACATTTTACCTGATAACAATCTGGATGTGGATGAGATTGTGATATCTTCGTCATCTTCCTATGCCTCCTCCCAGCAGCAGGCGGCAACCAAAGTTTCAGCAGTTCCACATCAGCCTCAGCATTCCAATCAAACACATCAAAGTCAGCAGCAGCTCACACAGCAAATGCAGCCCAACTCCTTCAacgattttaatttcaatctcTACCAGGCCACCGCTACTGGATCGACGGCAGTGGGCAAATTTAGCCCCTTCAATTTCCAGCCGCAGCAACCCACGCACAGCGGGACTAGTGAAGCCACCAATGCGGCCACCGTGGCCTCGTCGTCTAGTTCCTCGGCCAGTTCATCAGCCGGCTCCGTTATTATGGATCACGACTCCATGAATGCCACCTTCCCGGTGGCCAAGGATCGTCAAATCCGTGATCCCTCCTCTCTAGCCCAGGGCAGTGGTCCGAGTTCCTGGTATCAACACCAACCGCACGATGGTGCCCAGCCCACCAATTTCAATGCAGCACTCGCTGCCGTCGACTGCTGCAGTGTGGCCGTGGATGGCGATGCCAATGGGGCCAAATATCTAGATCTGGATACCTGCAAGCGGGAGCGTCCCAGTGgcagtagcagcaacaacagcatttCCATGACCACAGCCACAAATCTGTTATCCGGCTCGGTATCCGCCTCAACCACATCCTCTTCGTTTGCGGCTGCCGCAACTGAGAGCAGCCTGGTCGGAGGACTCAATATACGCACTGATGAGAAAATGCCCGCGAAGGGTGAAATTTCCGAGCAGGAAAGCAATTGTGACATTGAAAACTCCTGGAGTCAATCGATGTATGGCGGAGATCTATCACCGCGTTACTTTAGGAATCAATTCTCAGCTGGTTCATACAGTCACATGCCGGACTGGAGGGAAAATTATTACCCAGCCGAAGATTTGAGCTCTCCGCAACGAGACACAAAACGTTTCGACTTTCGTCTGCCCGTGGATGTGGCCAACAATTCAGTGGCCGATTATATGTTCCCCAATCAGGGCAATCAAGATTTGGATAGCTCCAGTGATCAAGAGCATTCCCTGCTGaccaataagaaaaataagcgCAGCGGCAGTCTTCACTTCATGGAAGATACACCCCCCTCAACGTCTTCGGCTTTGCTGGCTGGTCCACCTATAGCCTCGACCTCCCGGGCTGCCGCCGCAGCAGCTGCCACCTCAGGCCTGGGCAATAGCTTCTTGCCGCCGGCCACCATGGCACAGCCAAAACCGCCACGTCGCAAGATCTATAAATGCCCCCACTGCGAGGTCATCTTTGAGAAGCTAAAGGAACGCAATGCCCACATGATCAGTGATCACAACTATGTGCGTCAAAATCGTCGGCTCATCTGCACCCAGGCAGCCGTGGCAGGTCCCCCACAAGCCACTTCTAGCACAACGGCTGCTCAGCTGCTGGCCTCCCAGCAGGAACAGTTGTTGGCTatgcccagcagcagcagcggcatcAATTCAAGCACTCTGGTGGAGGACTCCAAAGATGGCATTATAAAGATCAAGCAAGAGCAGTGCTCggatcagcagcagcaaaagctACCCACCTCGCGTCGTGAAACGCTGGATCAGCTAGAAGCGAAGACCGAATTGCCAGATGTCAAGGACAGCGGTCTGCTGGTGGAGCCCACCAATGCGGATATCAAGCCACACGAAGCCCTACTCACCCAAATGGACGAGAAGCCCCAACTGCAGCCCCTAGCCATGACCACTCCGGCAGCCAAATTGGCTGCCCTCTATCGCATGCTTATTGCCTTCAATGAGTCAAAATTGGGCCAAGATCGCACCATCAGCGAGTTGGAGCAAAAGGCCATGGAGAAGTCAATTTTCCTCTGCTACGTCTGCCGCACGGATTTCCCTTCGGTGAAGCTATACGATGCCCACTTGACCGAGCATCCAGCCGAGTGTTTTACTTGTGGCAAAAAGTTTTATCGCTGGAAGAACTTCTCGCTGCATCTAAAGCGTCATCTGGGCTGGAAGGAATTCGGCTGCTATGTCTGtgacaaaaaatttgtagtcCGCAGCGCCCTTGTCGAGCATATGCGCATGCATACTGGCCAATCGCCgctcaaatgcaaaatttgcGgtaaAAAGTTTAAGCGTTATTCGAACTTGACGCAGCATCGTAAACGCCACACCAAGATGATTGTGCGCAAGAAGGAATACGTTTGCCATTGCGGCGAAGTGCTGCCATCCAAGGCGCGCTTCCTTTGGCACAAGGAGACCCACGACCTCAAACCCAAATGCTGTCCCTATTGCTGCGATCGTTTTGTACATGCCAATTCCTTGCGTCGACACATTCGTCTAGCCCACTCGGATAAATTCGACTATGCCGAGCCCATGGAATGCCCCATTTGCAAGCAGATCTTTGCCAAGACCTCGATCAAGGCGCACATGGCCACCCATTCAACCGAACCGCAATATGATTGCGCCATTTGCAACAAATCCTTCTCAACCAAATGGAATCTAAAGATTCACTCCTGGGTCCATGCCAATCGAACGGCCAAGCCCTTCAAATGCGATCACTGCCCCAAGGCATTTGTACGCGAACTGGACTTTAAGAACCATCTGAATGCccacaaacaaattaagccGTACACCTGCGAATATTGTGGATGCAAATTCATTCGTAAATACAACTACATGCGACATCGGCGCGAGCATCACGGCAACAAGAAGTTCACTTGCGATCAGTGCGACAAATCCTTCCATCGTCACTATTACTTGATTGAGCATCGACGCATTCATACGGGCGAACGGCCCTTCCAGTGCACCATTTGCGGCAAAAGTTCCACCACCAAGACCAATCATAATAAGCATCTAAAAATACATCATTCGCGTGATCCCTTCACCGTTGAAGTGTaa
- Protein Sequence
- MVESVQCPVCTLYLHAGMNLSDHLDTHPKEQVIKALVQMTIAGNGPANALAAVLASSGSDDTAASAGSGADVKPLGDTSSLSKLVSAIVTATATATTNTSASATSSSTVTAGLEPAEFVASSSSSSKPHSGNCHTNNKLNNPPTKQKYEGLKITMPNQPNPRLTAGEATSTLTPTTTTTASAATAATSNYQQQPQQALSLPAGEFRYEQQATPHFQHTNRTTVAATPALAYSASGLHPATPQPHPQQQHQHYVTTTQQLQRHGPQQHPPHSLHQPTHFATHQQSLKYYTTNLPPPPPLQLFGQLPTTSQSAQHQKPPPAYGAAISQIRSQHNQNKQQHQQHHPQQQQQQQQQQQHHHHQQQPQPPQTLTSITIHQIQPPTADAVAVAAAAAAASMATKQNNKTTAAAHTDIFFNLPPPPNPAPVANASTTGAATAVTSALPTSSGSNTRMPTPTPAHLAHLPHQPYAAASHLPVTAPQNPSGNNRPSQVSPARSAASSARQTNSPFGALLTAAAAAVCASPSSVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLRIHDDDDDDDDDEKEESHDPARHKKQENDERLADEGDYEREDSRSRPSTSNSAANKKQRSSKITKTKVNTKLGKSSQIPLKPIPDDVDMMSLSSGSDNEEPTQPLANTANHQPLSLSASTSNSNTLTHSATTDGNSNSNASGGTKSKKNRITVLSDVPLNMNEYLDLVGNIVASSRITASRPFAAMAPLPLVKVEKEEPLDDYDAESISAFSHQTHTPSAEIETEDVEQKPSLDDQLHVQQASGSVMSANNGGHCTTSVIRMASANAPPPTEDFTPEDLTQPPTMKIEVEPTALMPQRFAAPAIQQRGPKKLVIKPKSTTTATVAATKTKKTDIATATSTSITSLEPKASTSAAAQTLSISQTLIANTSALEVVHIKSEVCEPPSISMGSILEKHLTTNYGYPGQQSQQRRKISAVNDDDARVLLEFANSKQPPVDGSASTTFVVNAATFPSANSVFASGSTNATSTAHMGTQKKEEYILPDNNLDVDEIVISSSSSYASSQQQAATKVSAVPHQPQHSNQTHQSQQQLTQQMQPNSFNDFNFNLYQATATGSTAVGKFSPFNFQPQQPTHSGTSEATNAATVASSSSSSASSSAGSVIMDHDSMNATFPVAKDRQIRDPSSLAQGSGPSSWYQHQPHDGAQPTNFNAALAAVDCCSVAVDGDANGAKYLDLDTCKRERPSGSSSNNSISMTTATNLLSGSVSASTTSSSFAAAATESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGGDLSPRYFRNQFSAGSYSHMPDWRENYYPAEDLSSPQRDTKRFDFRLPVDVANNSVADYMFPNQGNQDLDSSSDQEHSLLTNKKNKRSGSLHFMEDTPPSTSSALLAGPPIASTSRAAAAAAATSGLGNSFLPPATMAQPKPPRRKIYKCPHCEVIFEKLKERNAHMISDHNYVRQNRRLICTQAAVAGPPQATSSTTAAQLLASQQEQLLAMPSSSSGINSSTLVEDSKDGIIKIKQEQCSDQQQQKLPTSRRETLDQLEAKTELPDVKDSGLLVEPTNADIKPHEALLTQMDEKPQLQPLAMTTPAAKLAALYRMLIAFNESKLGQDRTISELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQSPLKCKICGKKFKRYSNLTQHRKRHTKMIVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPICKQIFAKTSIKAHMATHSTEPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCDHCPKAFVRELDFKNHLNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFQCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -