Slat005068.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_037075145.1
- Location
- JBAMCM010000123.1:1331922-1334492[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.068 5.8 7.8 5.9 3 23 263 283 261 283 0.96 2 12 0.0016 0.13 13.0 0.5 1 23 289 314 289 314 0.92 3 12 0.0099 0.84 10.4 0.8 2 23 322 346 321 346 0.93 4 12 0.00025 0.021 15.5 2.0 1 23 358 380 358 380 0.98 5 12 2.3e-06 0.0002 21.9 0.2 1 23 387 409 387 409 0.98 6 12 0.0067 0.56 11.0 0.1 1 23 415 437 415 437 0.98 7 12 0.00081 0.068 13.9 2.1 1 23 443 466 443 466 0.98 8 12 0.0088 0.74 10.6 3.9 1 23 472 494 472 494 0.96 9 12 0.00015 0.013 16.2 3.6 2 23 501 522 500 522 0.96 10 12 3.9e-05 0.0033 18.0 0.3 1 23 632 655 632 655 0.96 11 12 0.01 0.87 10.4 1.2 1 19 661 679 661 683 0.94 12 12 3.7e-07 3.2e-05 24.3 3.2 1 23 689 711 689 711 0.99
Sequence Information
- Coding Sequence
- ATGAATATCGGGAGTCAATACTCCATAGACACCTTATGTCGCATCTGTTTGAATTATCTGCAAAACGATGCTGCTTACGATCTATTTTTGGTACCCGGATTGGCCAAAAAATTGTGCGTATGCACGTCTCTTTCGGTGGAACAACAGGATGGTTATCCAAAAAATCTGTGTTCTCTGTGTTATACCCGTCTCAACGATATGCACGAGTTTCAAATGCTGTGCGTGGAGTCAGTGCAAAAGTTTCAAAACCTTATAGCCACAAACAGCCTTGCCTGTCAGGTAAACACGTTCGATGTTCTGGAGGGAAATGACGGAACCGGCGAACCTGATCCCGATTTAGCTGGTGAGGAAGAAGATCGTGTGAACTTTGATCCCCTGTTAAAccacaaaatggaaattattgaaaacgaAGAAGATGTTTTCAAAATGCTGGAACATGTGGACAAAGAAGCCGAGGAAGTGGAAAAGGATGTCAAGCATGACGAAGTGCTACAACAAGACATGCTAAAAATGTTTACCCACGAATCCTCCAACGATAGCGAAGACGACGCAGACTTTGAACCCGATAGAAATAGTAGTGACGACGATACACCCTTGGCCCAGAGATTGCGCGGAAAAGCTTCCACCAAGTCCAGGTTGAAAAAGTCTACtgccaatgatgatgatgacgacgaagaTTTCACCTCAGAAACGgacaacgacgacgaagaTAATGAtagcacaaaagcaaaaccaaagcgCAAGCGTATTCCTGCTGCAGAGCGTCACCTACATCGCATCATCGACTGCCACATTTGTCACCAGAAATTCAAGAAAGCCATTCGATACGAAGAGCATATGAAGCACCACAACGACCTGTTGCCCTTCCAGTGCAAAGTGGAGACTTGCAAAAAAGGCTTCACCACAGCCGGTGGCCTGCGTCTGCATGTGGATCATGCTCATACCGAGCTATCCGAAGTTCATGCCTGCTCTGTGGAGGGATGCGACAAAACATTCCCGCGTATCCGCCTCTTAACCTTCCACATGAAGAAGGTCCACAACATCTCTAAGGCAGCTGCGCCGCCCCGAGACTACCCCTGCACCGAGTGCGAAAAAGTGTTCCGTTGTCCGATGGCGCTGAAGAAGCATATGTACAAGCACGATGGCAAGGAATTACCCTTCCCCTGCAACATCTGCGGCAAGCGATTCGTCATCAACAGCGCCCTCAAGGATCATCTCATGCGCCATGCCGGCATCAAAAACTATGTGTGTCCCTATTGCGGTGTAGGCAAGACCACACGCCAAGAATGGAACACACACATCCTCACCCACACCCaggaaaagaaattcaagtgCAACATCTGCGACCATGCCTCCCACAACAAACAAAGTCTGGCCAATCATATCAAGATTGTGCACGAGAAGATTAAGAATTACGCCTGCCAGTACTGTGGCAAGACCTTTGGCAAGTCACACGCCTGCAAGATTCACGAGATGACCCACACCGGCGAGAAGCGTTGCGAGTGCAAGGTCTGCGGCAAGAAGTTCCTCTACCCAAAGAGTttaacaaaacatttaaagacACACGAGAAGCGTGTCTTGCGTGCCATCGAAACTTATCGCCAGCGCCAGGTGGAGCTAGGCGAAGGAACACCTTCCGGATCAGACCCCATAGATAACTTGGTAGCCGGACTCACCAACAACGCCGAAGGCGTCGAACCGTCCATGCCCCAGAATGCTGCCGACGAACTACTCAAGGTTTGTGCCGAATCAGTGGCCACCATACCCAAAGACCCACGACGAGTTCAACGTGTGGACATAGCTCAGCTGGCGGGAACAGCTGTGAATCCCATACCGTCTGTGTCAGTGCCTTCCTGGTCGCCTCAGGTCAACTTTACGAAAAAGGAGGGCAAGCACATCTGTCCCGGCTGCGGTCAGGGCTTTAATAACATCGGCAACATGAAGCGCCACTACAAGATTATCCATGAAAAGGTCAAGGACTTTGCCTGTCGTTTCTGTCCAAAGCGCTTTGCCAAGGCGCAAACTCTACGCCACCACGAATGGATACACACTGGCGAAAAGCCTTTTGAATGCAAGATATGTGGTACACATTTCCGCCAAGAGACAGCTCTGAAGCGACATCAAAGGACCCACGAGAACAGACCACCAGTTATTTCCTCCAAGTTCTATGCGGCTCGCGAAGAGCTGGAAGAGCAAGAGCGCAGCAAACGGGAAGCCAGGCGAAAGGCAGATGCAAAGCGCAAGGAGATTGCCGACAAGGCCAAGGCACAACTTCAGAAAATCGAGGCCACCGACAAGAATCTACACTCCTACGACGAATACCAGGAGGCCGCCGCCGAGAGAGCTGCTGCCTCCGCCGAATTGCAGGCCCAACAATTCGAGGAGAACGAAATCAAGCGCAAGGCCGACGAGGAACGACGAAAGATACAAGAGGCCGCCTACGAGCAGCTGGAGGTcttgcagcagcaacagcaattcGATAAGGCACAAAGCTCCTATGATGGCTACTATGCCCAAAAGGCCACCGCCGAAGGCACCAGCCTTGATGCCCTCAAAATTGACCATGTCTAG
- Protein Sequence
- MNIGSQYSIDTLCRICLNYLQNDAAYDLFLVPGLAKKLCVCTSLSVEQQDGYPKNLCSLCYTRLNDMHEFQMLCVESVQKFQNLIATNSLACQVNTFDVLEGNDGTGEPDPDLAGEEEDRVNFDPLLNHKMEIIENEEDVFKMLEHVDKEAEEVEKDVKHDEVLQQDMLKMFTHESSNDSEDDADFEPDRNSSDDDTPLAQRLRGKASTKSRLKKSTANDDDDDEDFTSETDNDDEDNDSTKAKPKRKRIPAAERHLHRIIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCKVETCKKGFTTAGGLRLHVDHAHTELSEVHACSVEGCDKTFPRIRLLTFHMKKVHNISKAAAPPRDYPCTECEKVFRCPMALKKHMYKHDGKELPFPCNICGKRFVINSALKDHLMRHAGIKNYVCPYCGVGKTTRQEWNTHILTHTQEKKFKCNICDHASHNKQSLANHIKIVHEKIKNYACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYPKSLTKHLKTHEKRVLRAIETYRQRQVELGEGTPSGSDPIDNLVAGLTNNAEGVEPSMPQNAADELLKVCAESVATIPKDPRRVQRVDIAQLAGTAVNPIPSVSVPSWSPQVNFTKKEGKHICPGCGQGFNNIGNMKRHYKIIHEKVKDFACRFCPKRFAKAQTLRHHEWIHTGEKPFECKICGTHFRQETALKRHQRTHENRPPVISSKFYAAREELEEQERSKREARRKADAKRKEIADKAKAQLQKIEATDKNLHSYDEYQEAAAERAAASAELQAQQFEENEIKRKADEERRKIQEAAYEQLEVLQQQQQFDKAQSSYDGYYAQKATAEGTSLDALKIDHV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575777;
- 90% Identity
- -
- 80% Identity
- -