Slat002257.1
Basic Information
- Gene Symbol
- -
- Assembly
- GCA_037075145.1
- Location
- JBAMCM010000100.1:9153654-9156582[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.002 0.17 12.6 0.8 1 23 185 207 185 207 0.96 2 17 0.4 34 5.4 4.8 1 23 213 235 213 235 0.95 3 17 0.074 6.2 7.7 1.6 1 23 361 384 361 384 0.91 4 17 3.4 2.9e+02 2.4 0.1 3 22 395 414 394 414 0.94 5 17 2.5 2.1e+02 2.9 0.5 1 20 423 442 423 444 0.91 6 17 0.13 11 7.0 7.7 2 20 459 477 458 480 0.93 7 17 0.017 1.5 9.7 0.3 1 23 557 580 557 580 0.89 8 17 0.0037 0.31 11.8 0.0 1 22 591 612 591 612 0.96 9 17 0.38 32 5.5 2.5 1 23 621 644 621 644 0.95 10 17 0.00025 0.021 15.5 0.5 2 23 669 690 668 690 0.97 11 17 2e-05 0.0017 18.9 7.2 1 23 696 718 696 718 0.98 12 17 9.9e-05 0.0083 16.7 2.0 1 23 748 771 748 771 0.97 13 17 2.8e-06 0.00024 21.6 0.4 2 23 793 814 792 814 0.95 14 17 0.00028 0.024 15.3 2.8 1 23 820 842 820 842 0.99 15 17 0.00028 0.024 15.3 4.1 1 23 848 870 848 870 0.97 16 17 6.2e-07 5.2e-05 23.7 4.9 1 23 876 898 876 898 0.99 17 17 0.00014 0.012 16.3 0.4 1 23 904 926 904 926 0.97
Sequence Information
- Coding Sequence
- atgtcAATGGGCAGTGTGTGCCGCACCTGTGCCTTAGACAATTGCCAAGCCGGGGCAGTGTCTTTATTAGCTTACACCGAAAAACACGGCAAGACCTTGTATGAAATCTTGCAAGAATTAATTCGAATAGATATAAATCCCTGCATTGAAGAAGTGGAAGGCCACCAAATGCCGCGTTGCATTTGCAGTGATTGCTACGAACGCCTTAAGAGTTCCTATGATTTCGTATGCGAGGCGCAACAGGCAAACAAGAAACTCGAAAGCCTGCGCGCAAGCGTACTAAGTCAATGTCTGGATGAAGTGCCCACAGACTTGCCCACGCTATTGAATATCAAAACAGAAggtgaaattgaaatagatgAAATCGGTGTGTCCTTTGAGGAAACCGAGAGTCTGGGTAGCATTTACTGCGAGGCCAATAAAAGAGAACCGAGTGAAACAGAAGACCAGGACTATAAACCAAATCAGAccgaaaaatacaaagaatcTTGTAAAGCAAAAGCgCCTTCGGATAATGATGCATCAAAAAGACCTACAAATTCAGAGGGCCGCTTTGTGTGCGAGGTGTGTGACAAAACCTTTTCCTGGCATCGGGATATGCTGCGCCATGCACGAGCTCATTTTGAAGAGGCCACATTTACTTGCAGCTTTTGCAACAAGACATTTCTACGCAAGGATAAATATATGTTCCATCTCAAATCTCATGAAAAACGCCAGGCCAAATCCGAGGCACTACAGCAAAAGGCCGAATGGCGCTTTGCCAGGCGCTTGTACAGCCCAGGACGGATTAAACGTATTGAATGCAAATTATGCAATAATCGCTGTCAACATATTAAAGATCTCCGcattcatttgaaatgccaTGACCAAGTAGAAACCTTAGCCCATCTGAGCAACGATAATGATGTGATCAGAATTCACTTCGATGGCGGTAAAAATTTGAGCCTAGACGAGATAAAGCACCAAATAATTGCCGACATAAAAGCAcaaaagatagaaaaatatGGCGCTGTGGTAAATTCCTATGGCTATGAGCTCTGTCTCAGCGATTCGGATGAAGAAGGCAAGGACAAATACCAGTATCATTGTGGTCCCTGCAATTTATCTTTCACTCGGAAGTTTCGTCTTATAAATCACACTTTGGAGGAGCACAGCCAGCGGAAATCTGCACCAGCCGAAATGTGCTCCGCCTGTAAGATTGGTTTCGTAGATGACGATTTCTTTGAGCAGCACAAAAGGACTCAGTGTCTCAATCAACTAAAACGTTTCAATTGCTTGAAATGCCCAGGGCGATTCATGTGGCCAgagaatttgaataaacatGCCTGCTCCCAAAACCTAACGGGagaaaaatcagaaatctTACTAAACTGTCAATGCTGTCTTTGCGATcagcaattttcaaaactgtcACATCTGCGCGCCCATTTGCCCCATCATTCGGATGGACACTCTGGCATTGATTCTACCAGCCAAGCGgccttttttatggaatttggCAATGAATTCGCTTCAAATGAAGTGATAGAAGCACGCATTGCCAGTGATTTTTTGGCTCAGGATTATGTCCGCTACTACAACGCCAGCACGGACACGGGTCAGGAACTGGATCTCTACGATGGCGATGAAAGTGAGTCTGAAGAAGCGAATCATTTGTCTCAGTTGGTACACAATTGTGTGATTTGTGGCGAGGATTTTCAACGTCTCAGTCGGTTACTTCAGCATCAGGGCGAAGCTCATGCCAGTGAGGAGACCCAGGGTATCTTTCCTTATGTCTGCAGCACTTGCGGACTTGGCTACGTCAGTGAGGCCTTGCTTATCCAACATCGTCGCAGGCTCTGCGACAAGCAGCATGCTAAGCATGTCTGTCAGAGTTGTAATACCCGATTTATCTGGAAGGTCAACTACCATCGCCACCTGGAGGTCATCCATGGCATTGCCTGCGAAAAGGGTgttaccaaaaagaaaaagtatagACCGCGTGGGTCGAAGTTGGCCAAGTTGCAGTGCGATGAGTGCGATAAAGTCTTTATATGGCTCAAGGATCTGACGCGACACAAGAAGATGCATATGCCGCACTCGAAACATAAGTGTCCGCATTGTGACCGAAAGTTTCATCGCAAAGACGGTCTCAAATCCCATCTCAGAGTGCATAAGCAAGATGAAAAGGCAACAGATATTTTAGAGCCAACCTTAGAGCCAGATGGAGTCACTGAATCAGTAGAATCTACTGATCAAATCTTTCAGTGCCTTGAGTGCCCACGGAAATACAAGCGCAAAGATCGTTTGACCGCACACGTTAAGAAATTTCATACGCCTGGTGTGAGTCCAGTAAAAACTGAGACAACTCAGCTGGTAGGACTGAAGAAAAGTTTCCTCTGCGCCTTTTGTGGCAAAACCGTAAGTTCGTCGTCTAATCTAGTGATACACATGCGTCGGCATACTGGGGAGAAACCCTTTAAGTGCGACCAGTGCGATATGGCGTTTCCTCGCACATCGGATCTACAGTGCCATCGCCGGACCCATACTGGGGAAAAACCACATGTCTGTAGTATTTGTTGCAAGGGGTTTGCCCGTTCCTATAAGCTTCAGCAGCACATGCGTATCCATAGCGGCGAACGACCGTACAAGTGCACCTATTGTGAAAAGTGTTTTACCCAGTCGAACGATCTTACTCTACACATACGTCGTCACACTGGCGAACGTCCTTATCAGTGTGATACTTGTGGAGAACGATTCATACAGGGCACAGCTTTGAAAAATCATCGACTACAACATGGACACCTTGCAAAAAGTGAGGAACTGGAATCCGTACTGTAA
- Protein Sequence
- MSMGSVCRTCALDNCQAGAVSLLAYTEKHGKTLYEILQELIRIDINPCIEEVEGHQMPRCICSDCYERLKSSYDFVCEAQQANKKLESLRASVLSQCLDEVPTDLPTLLNIKTEGEIEIDEIGVSFEETESLGSIYCEANKREPSETEDQDYKPNQTEKYKESCKAKAPSDNDASKRPTNSEGRFVCEVCDKTFSWHRDMLRHARAHFEEATFTCSFCNKTFLRKDKYMFHLKSHEKRQAKSEALQQKAEWRFARRLYSPGRIKRIECKLCNNRCQHIKDLRIHLKCHDQVETLAHLSNDNDVIRIHFDGGKNLSLDEIKHQIIADIKAQKIEKYGAVVNSYGYELCLSDSDEEGKDKYQYHCGPCNLSFTRKFRLINHTLEEHSQRKSAPAEMCSACKIGFVDDDFFEQHKRTQCLNQLKRFNCLKCPGRFMWPENLNKHACSQNLTGEKSEILLNCQCCLCDQQFSKLSHLRAHLPHHSDGHSGIDSTSQAAFFMEFGNEFASNEVIEARIASDFLAQDYVRYYNASTDTGQELDLYDGDESESEEANHLSQLVHNCVICGEDFQRLSRLLQHQGEAHASEETQGIFPYVCSTCGLGYVSEALLIQHRRRLCDKQHAKHVCQSCNTRFIWKVNYHRHLEVIHGIACEKGVTKKKKYRPRGSKLAKLQCDECDKVFIWLKDLTRHKKMHMPHSKHKCPHCDRKFHRKDGLKSHLRVHKQDEKATDILEPTLEPDGVTESVESTDQIFQCLECPRKYKRKDRLTAHVKKFHTPGVSPVKTETTQLVGLKKSFLCAFCGKTVSSSSNLVIHMRRHTGEKPFKCDQCDMAFPRTSDLQCHRRTHTGEKPHVCSICCKGFARSYKLQQHMRIHSGERPYKCTYCEKCFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRLQHGHLAKSEELESVL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -