Basic Information

Insect: Scaptodrosophila latifasciaeformis
Gene Symbol: wek_1
Assembly: GCA_037075145.1
Location: JBAMCM010000100.1:13495628-13501308[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 9 7.6e+02 1.1 0.2 2 16 80 94 79 96 0.82

2 22 0.068 5.8 7.8 0.9 2 21 319 338 318 339 0.93

3 22 0.0021 0.18 12.5 0.2 2 23 355 377 354 377 0.90

4 22 0.17 15 6.5 0.5 1 23 383 405 383 405 0.94

5 22 0.036 3.1 8.7 1.6 1 23 411 433 411 433 0.96

6 22 0.001 0.087 13.5 0.5 1 23 438 460 438 460 0.98

7 22 5e-05 0.0042 17.7 0.5 1 23 466 488 466 488 0.98

8 22 1.3 1.1e+02 3.8 5.8 1 23 494 517 494 517 0.83

9 22 0.4 34 5.4 0.8 5 21 616 632 615 633 0.92

10 22 9.5e-05 0.008 16.8 2.7 2 23 649 671 648 671 0.96

11 22 0.01 0.85 10.4 1.5 2 23 706 727 705 727 0.95

12 22 0.00031 0.027 15.1 1.0 1 23 732 754 732 754 0.98

13 22 0.0055 0.46 11.2 0.1 1 23 760 782 760 782 0.98

14 22 0.0035 0.3 11.8 5.5 1 23 788 811 788 811 0.97

15 22 2.8e-05 0.0023 18.5 1.7 1 23 1072 1095 1072 1095 0.94

16 22 6.2e-05 0.0053 17.4 2.0 2 23 1106 1127 1105 1127 0.97

17 22 0.00032 0.027 15.1 2.5 2 21 1138 1157 1137 1160 0.94

18 22 0.00046 0.039 14.6 0.2 1 23 1166 1188 1166 1188 0.97

19 22 0.00026 0.022 15.4 3.0 1 23 1194 1216 1194 1216 0.97

20 22 0.0052 0.44 11.3 0.2 1 23 1221 1243 1221 1243 0.96

21 22 6.6e-06 0.00056 20.4 0.5 1 23 1249 1271 1249 1271 0.97

22 22 0.01 0.88 10.4 5.9 1 23 1277 1300 1277 1300 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	9	7.6e+02	1.1	0.2	2	16	80	94	79	96	0.82
2	22	0.068	5.8	7.8	0.9	2	21	319	338	318	339	0.93
3	22	0.0021	0.18	12.5	0.2	2	23	355	377	354	377	0.90
4	22	0.17	15	6.5	0.5	1	23	383	405	383	405	0.94
5	22	0.036	3.1	8.7	1.6	1	23	411	433	411	433	0.96
6	22	0.001	0.087	13.5	0.5	1	23	438	460	438	460	0.98
7	22	5e-05	0.0042	17.7	0.5	1	23	466	488	466	488	0.98
8	22	1.3	1.1e+02	3.8	5.8	1	23	494	517	494	517	0.83
9	22	0.4	34	5.4	0.8	5	21	616	632	615	633	0.92
10	22	9.5e-05	0.008	16.8	2.7	2	23	649	671	648	671	0.96
11	22	0.01	0.85	10.4	1.5	2	23	706	727	705	727	0.95
12	22	0.00031	0.027	15.1	1.0	1	23	732	754	732	754	0.98
13	22	0.0055	0.46	11.2	0.1	1	23	760	782	760	782	0.98
14	22	0.0035	0.3	11.8	5.5	1	23	788	811	788	811	0.97
15	22	2.8e-05	0.0023	18.5	1.7	1	23	1072	1095	1072	1095	0.94
16	22	6.2e-05	0.0053	17.4	2.0	2	23	1106	1127	1105	1127	0.97
17	22	0.00032	0.027	15.1	2.5	2	21	1138	1157	1137	1160	0.94
18	22	0.00046	0.039	14.6	0.2	1	23	1166	1188	1166	1188	0.97
19	22	0.00026	0.022	15.4	3.0	1	23	1194	1216	1194	1216	0.97
20	22	0.0052	0.44	11.3	0.2	1	23	1221	1243	1221	1243	0.96
21	22	6.6e-06	0.00056	20.4	0.5	1	23	1249	1271	1249	1271	0.97
22	22	0.01	0.88	10.4	5.9	1	23	1277	1300	1277	1300	0.98

Sequence Information

Coding Sequence: ATGAAaggccaattaaaaaataaaaactctcaAAAAGATCCATCAACGCGTTCGCAAGTAAAGACACTGAACTGGAATATCTGGTGTCGCCTTTGTGCCAAAAAGCATCGCGACAATGTAAACGTCTACTTTTGTACAAATCAGCAGGAACAGGAGCACTTGGCCGCATGGGACAATGTTATTGTGATGGCTAtacgcaaatattttgatgtcAACATTCTTCCCGGAGACGAAATAAGCTGTTCGCTGTGCCCGCAATGTTACACACTCGTCAGCGAATTGCTAGACTTCTCCGACCATGTGAATAAGGTGCAGATAATCTTTGATATGCTACGCCactcaaatccaaaaatagAAGTCGATGAGGCATCCTTACGTATGCAATATGGCCTGAGGGATGACGACTGGAAACACATTATAAAACCTTTGGATAATAAAACAAGGTTAGATCACAAAGATGAGAAACCCGACTTAGCAGAACTAAACATGGGTGTcggaaatgaaagaaatttcaaaagtgaCGAAGAAAAATTGTCTAATGAATTGACGAAGCAGGAAATTGTGGTAGTAGACGATAGCGAACACAGGGCCCTCACAGTGGAATATAAAAGCCCAACGAAAAGAGGTCGAGGCCGTCCTCCGAAACAAAAACCCACTGAAGTGCAAGAATCCACAACACTGTCGCCAGCTGAACCTGataaagaaatggaaaatgcgAATATCAATTTTATGGAGTCACCCGTAGCCGAAGGGTCTCATAGTCCAACAACGCATGCAGAAGAAGACATAGATAAAGTTTTTGAAGAATTCATATCCGAAGTAGGAGACTTAGAAGGCAGTGATTCAGATTCAGAGGACTTGCTAGAAGACGAAGAATTTACCCAAAGCGAAACAAATTCCATTCCATCAGCTGATAACAATAGTTTTGGCATCCTCACAAGAGAAGGTCACATAGAATGCCAAACCTGCGGTGCGtgttatataaatcaattggCCTTTAACAAGCATAAGAAACGCGGTTGCACGCAAGCTAAGCAGAGGCGGAAATCGTCAAAAAAGAAGTCCTGCGACGTCTGCCAAAAGACATATTCTTCTGCTGCTGCACTAAAATTGCACAAAGAGGGAATGCATGAAAACTTAAAGCCCTTTATTTGTGACTGCTGTGGTAAGGCCCTTAAAACAATCACAGCCTTAAACGAGCACAAATTGGTACACACCGACGAAAAACCATTCATTTGTAAAATCTGTAATTCCGGCTTCAAGAATCTCAAGCGTTTAAAATATCACAATCAAATACATGGAGAGCCCAGCTACGAATGTGAAATTTGCGGGAAAATGTTACAGACGCGGCGCACTTGGAATAAACACAAATTGGTACATACCGAAGAgcgaaaatttaaatgtggAGCCTGCGGAAAAGGTTTTAAATACTCCACGGCTTTAAAGAGCCACTTGCTCAGTCACAATGGAATGCGTCCGTATGCTTGTAAATATTGCGATAAAACGTTTGCCTGTAATGTAAATTGCCGAgctcacaaattgaaaaagcacCCTAAGGAAGTTGAACGAGAAGGCAAGGAAAGCCTACTATCCTCGAGACTTAATGTGCCAACACTGGATGAGCTGCGAGCTATTTCAGATTCGAATATTGATGTGGCTTCTCTTCGCCTACAACACGGACTCGGCAATCCAATCAAGCttaaaattctcaaagaaGAGCTGCGGCCTATGAATATAAAGACAAGCGAAGGAGAGAGCTCCGAGCACCCGCTACAACAACAGGAATTCGTGGCAGTAGAAGGCAATGAAAGCGGTATCGTGACAATGGAACAATATGTCATAAGAGAGTGCCATAATATCTATAAACATCGTGCTTCCCTGcgaaagcatttaaaaataggcTGCAAGAAAGCCAATCAGCGTCAGAAGTTGGGAAAGAACACCACATGTGAACTGTGCCATCGGAAATTCTCAAAGGCTTATGCCCTGAAAACGCATATGAAATATGTGCATGAGAACTTAACACCATTTATCTGTGATTGCTGTGGTGCCGGTCACAAGTCCTTAGGGGACTTGAACAAACACAAGCTAGTCCATACTGAGGAACGCCCTTGCGTCTGTGAGGTTTGCAATGCAGCTTTCAAGAATTTAAAGCGCCTGAAGACTCACAAAGAAATACATGGTGAGCCTAGCTATGAGTGTGACATTTGTGGAAAGAAACTGCAGACTCGTGTCACATTCAACCAGCATAAAAGGGTCCACGCAGGCGAGCGTAAATTTAAATGCGGTGTATGTGGAGCTGGTTTTAATTATCGCACTGTACTCAAAGGCCATTTACTGAGCCACACTGGTCTGCGTCCGTACGTTTGTAAATATTGCAAGAAAACCTATGCCACCAAGAGGAACTGCCAAGCTCATCAGTTGAAGAAGCATGCAAAAGAAGTCGAAATGGAAGGCGAAGATGGAGTATCTCCATCGCGGTTGACTGTACCTACACTGGTTGAGCTGCGTGCCATGTACGGCAAAACATCACCAGCTCAGGTCACCTCGACAACGGCAGACTGGCATATGTGGTGCCGCCTGTGCGCCAAGGAGCATccggaaaacaaaaacgtcTACCTCAAAGATGGCGGGGAAGCCTTTCTGGCTGTGGCGATTGGCAAATACTTTTGGGTAAATATTAAAAGGGATGATGAGCTGAGCAATGCGCTGTGCAAGGAATGTTACACCCTGGTGGAGTCATTGATTCAGTTTTCAGAGCGCGTCAACCGAGTGCAGGCACTATTCAATCGACTGCATCTTGCCTCTCCAAAAGAACAACTAGACTTGAACGAAATACGGGATCAAAGTGGCTTGAACTCGGATAAGTGGAAACATATTATAAGCAATTCGGAGGACATAGAACGACCAGCTCAAGTGAAGCCAGTGTCATTTATTGAAGAAGGAGCCTCCGAGTCTTTTGATGAAGATGCAGAGATATTGGCTGAAATTGTACATGAGGAACACTTAGATGCCGAGTCTGAAACGTTTCAGGGATTTGTGGTCCATGATGAAGAGTTAGACAGTTCCTTGGAAGTTGAACAAGAGTCAGCTAGTGAAATTGTAATCAAAGAAGATCCTGAATTTGTACAACTTTCACAAGAAGAGCTAGATGATACCACATCCATCACATTCGATGTTATAGAGGAGGATTCTTCCAAGTCTCAGCATCAGTACAAATGCTCCATTTGTGGTAAATGCTATAAGAGTCCTCTAACCTATAAGAAGCATATCGAAGGGGCGCATCCCTCAGAGTCTTCCGAATTGCAGAAtcttaaatgcaaatattgcCAACGAATATTTACCTCAGAGAATCGCTTGACTGCCCACTATCGCACACATTTGgccgaaaaggaaaaatacaaGGATACCACCTGCAGTTactgcaataaaaattacccAACGCAGGCCTCGCTCAAACGGCACATTAACTGCATGCACGAACATTTAAAGCCCTTCATGTGCGACACTTGTGGCAAGGTGCTGAAGACTCTAACTGCCTTGAACGAGCACAAATTAGTTCACACCGATGAATGCCCCTTCGAGTGCAATGTCTGCCATCGTCGCTTCAAAAACAAGGCCAGACTTAAAaTGCATGCCGACACTCATGGCGGTAGCGTATACGAGTGCGACATCTGTGGCGTTAAGTTGAATACCCGGCGCACCCTAAATATGCACAAGGTGGTTCACTCCAATATCAAGCAATATAAATGTGACATTTGCGGTGCCGAGTTCAAACGCAGCAAGACACTGAAATCCCATTTAATCTTACATGCCGGCCTGCGTCCctataaatgtaatttttgcGGCCAAACCTTTACCAATGGTTCCAACTGCCGCATGCATAAACGTAAGACACATCCAGAGGAATTGGCGGCCGAAGAATCACAAGGCGTGGTGCGCTCCACCACATTGCCTATGCTGACTGAACTGACAGAAGCttcCAAGAAATACAAGAAGAATCAAAACAAGCAGGAGGGAGAGAAAATCCAGATGGTCTTGGTGACCGAAGAAGACGTAGACGATCAATTGGAAGAGGAATCTGGCACTGCTGACAATGTTTTAAGATTGGTATCCACGGAGAGTGCTCCTCAGTCAGATGAATTCTATGGTACCTGCGCTGATATGATTGAGTTTGTGGACGAATTGGAAGAttag
Protein Sequence: MKGQLKNKNSQKDPSTRSQVKTLNWNIWCRLCAKKHRDNVNVYFCTNQQEQEHLAAWDNVIVMAIRKYFDVNILPGDEISCSLCPQCYTLVSELLDFSDHVNKVQIIFDMLRHSNPKIEVDEASLRMQYGLRDDDWKHIIKPLDNKTRLDHKDEKPDLAELNMGVGNERNFKSDEEKLSNELTKQEIVVVDDSEHRALTVEYKSPTKRGRGRPPKQKPTEVQESTTLSPAEPDKEMENANINFMESPVAEGSHSPTTHAEEDIDKVFEEFISEVGDLEGSDSDSEDLLEDEEFTQSETNSIPSADNNSFGILTREGHIECQTCGACYINQLAFNKHKKRGCTQAKQRRKSSKKKSCDVCQKTYSSAAALKLHKEGMHENLKPFICDCCGKALKTITALNEHKLVHTDEKPFICKICNSGFKNLKRLKYHNQIHGEPSYECEICGKMLQTRRTWNKHKLVHTEERKFKCGACGKGFKYSTALKSHLLSHNGMRPYACKYCDKTFACNVNCRAHKLKKHPKEVEREGKESLLSSRLNVPTLDELRAISDSNIDVASLRLQHGLGNPIKLKILKEELRPMNIKTSEGESSEHPLQQQEFVAVEGNESGIVTMEQYVIRECHNIYKHRASLRKHLKIGCKKANQRQKLGKNTTCELCHRKFSKAYALKTHMKYVHENLTPFICDCCGAGHKSLGDLNKHKLVHTEERPCVCEVCNAAFKNLKRLKTHKEIHGEPSYECDICGKKLQTRVTFNQHKRVHAGERKFKCGVCGAGFNYRTVLKGHLLSHTGLRPYVCKYCKKTYATKRNCQAHQLKKHAKEVEMEGEDGVSPSRLTVPTLVELRAMYGKTSPAQVTSTTADWHMWCRLCAKEHPENKNVYLKDGGEAFLAVAIGKYFWVNIKRDDELSNALCKECYTLVESLIQFSERVNRVQALFNRLHLASPKEQLDLNEIRDQSGLNSDKWKHIISNSEDIERPAQVKPVSFIEEGASESFDEDAEILAEIVHEEHLDAESETFQGFVVHDEELDSSLEVEQESASEIVIKEDPEFVQLSQEELDDTTSITFDVIEEDSSKSQHQYKCSICGKCYKSPLTYKKHIEGAHPSESSELQNLKCKYCQRIFTSENRLTAHYRTHLAEKEKYKDTTCSYCNKNYPTQASLKRHINCMHEHLKPFMCDTCGKVLKTLTALNEHKLVHTDECPFECNVCHRRFKNKARLKMHADTHGGSVYECDICGVKLNTRRTLNMHKVVHSNIKQYKCDICGAEFKRSKTLKSHLILHAGLRPYKCNFCGQTFTNGSNCRMHKRKTHPEELAAEESQGVVRSTTLPMLTELTEASKKYKKNQNKQEGEKIQMVLVTEEDVDDQLEEESGTADNVLRLVSTESAPQSDEFYGTCADMIEFVDELED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -