Slat001468.1
Basic Information
- Gene Symbol
- su(Hw)_1
- Assembly
- GCA_037075145.1
- Location
- JBAMCM010000100.1:1919165-1922178[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00059 0.05 14.3 2.2 1 20 233 252 233 254 0.94 2 12 2.5e-06 0.00021 21.8 0.4 3 23 305 326 303 326 0.93 3 12 0.032 2.7 8.8 0.1 1 23 332 354 332 354 0.92 4 12 6.1e-07 5.2e-05 23.7 2.1 1 21 361 381 361 381 0.96 5 12 2.9e-06 0.00024 21.6 0.6 2 23 394 415 393 415 0.96 6 12 0.00016 0.013 16.1 4.1 1 23 426 448 426 448 0.98 7 12 7.2e-05 0.0061 17.2 0.9 1 23 454 476 454 476 0.97 8 12 8.3e-06 0.0007 20.1 0.7 1 23 482 504 482 504 0.98 9 12 9.2e-07 7.8e-05 23.1 3.1 1 23 510 532 510 532 0.98 10 12 3.6e-06 0.0003 21.3 0.7 1 23 536 558 536 558 0.97 11 12 0.013 1.1 10.0 0.6 2 21 567 586 566 590 0.85 12 12 6.5e-05 0.0055 17.3 0.3 3 23 608 629 606 629 0.96
Sequence Information
- Coding Sequence
- ATGAGTAAGAATGAGAAGAAGTCCACTGCGGTGGAAAAGGAGAAACGCAACGCCTCAACACTGCAAATCGTAGATGACTCACAAATATCACCAGCCCGGGAAAAACGCAATTCTAGTACGACAACTACAGGCACATCCCGCATAAAGCTACTCAACGATGCGGCATCATCAGGGGGGAAAGCCAGCGTTAAGCAGGAAAAACGCCAAAGCACCAGTGGAGGCGGCCGTATCAAAATTCTCAATGAAGAGACCCTTACTGGCAAATCTAAATCCCCAGACAAACGTGCCAGCATCTCAGCTACCACTAAAAAATCTGCTACTCCGACAAGCACCGTAAAGATATTAAATGACAAACGCGTAACACCCGCCGCCACTTCTgtggaaacaacaaaaatcaagacatcccctacaaaaaaaaagaaaatggatcACTATGTCTTGCAGTCCGTAAAAAGCGAAGCGAATAAGGCAGATAATACGGGAGATGGTGTGGAGGACGAGAACGACGAAGAGGATAACATTGCTTTCATTCTGGCTGACGATAATATTTTAGAGAGCACAGAAGCCAGAGATACGGCCAGCGGTGAAGAAATCGAAGAAATTGAAGAAGGCAGTGATGACGAAGCCGGTGAGGCCAGTAGCGAAATAGGACAGCAACGTTCCACTGGAAAGAATGGCATGAAGGAAATCGTTGAGCATGTCTGTGGTAAATGCTACAAAACATTCCGACGTGTGAAAAGTCTAAAGAAACATCTAGAATTCTGTCGCTATGACAGTGGCTACCATCTGCGCAAGGCAGACATGCTGAAAAATCTGGACAAGATTGAAAAAGATGCTCTGGTTATGGAGAAGAAAGACATATGTTTTTGCTGCAGTGAAAGCTACGACACTTTCCATCTGGGCCACATCAATTGCCCAGATTGCCCCAAGTCTTTCAAGACACAGACCAGCTATGAGCGTCACATTTTCATCACGCACTCGGAGTTTAATGATTACCCCTGTTCCATTTGCAATGCCAAACTGCGTAGTGCGGCACTTCTCAAGCTACACGAGGTCCAGCATCAAATCCGAGGCAAACCCTATGCCTGCAAGATTTGCGGCAAAGACTTCACACGCTCCTATCACCTGAAGCGCCACCAGAAGTGTTCCTCCTGCTCGGCCAACGAGAACGACACCATGAGCTGCAAAGTGTGTGATCGTGTCTTCTATCGCCTGGACAATTTGCGCGCCCATCTCAAGCAGCATTTAGGCACACAGGTGGTCAAAAAGCCGGAGTACATGTGCCAAACATGCAAGAATTGTTTCTACAGCTTATCAACCCTTAACATACACATACGTACACATACTGGCGAGAAACCGTTCGATTGCGATCTATGCGATAAGAAGTTTTCCGCCTTGGTGGCGCTCAAGAAGCATCGTCGCTATCACACCGGCGAAAAGCCCTATAGTTGCACTGTGTGCAACCAATCCTTTGCGGTCAAGGAGGTGCTCAATCGCCACATGAAGCGTCATACTGGCGAGCGTCCGCACAAGTGCAACGATTGTGGCAAGAGCTTCATCCAAGCCACCCAATTGCGCACTCATTCCAAAACACACTTGCGTCCGTTTCCCTGCGATGAGTGCgatgaaaaattcaagaccGAGAAACAACTCGATCGTCATATGAAGGAGCACACACGCCAGAAGCGCTCAGCACATATGTGCGTGCCCTGCAAGAAGTCATTCCGCACAGCAGAGCTCTTGGAAGAACACACCAAAGCTGGAAAGCATACACCACCGAAGCCAAAGCGCCCACCAGCAAAAGTTATTGAGCGCACAGACTGCGCCATTTGTGACAAGAACTTTGACAGTACCGAGACCTTGCGCTCCCACATACGCTCTGTGCATGAGTGTAATCCTGATGATATCTTTGGCACAGTGGCTCCACCCCCGTCAAAGCGGCCGAAGCGAGGCAAGAAGACTGAGGCAGTGCCAGACTCTCCCGATCCACCAGGTGCCCTCATCTCGAGCAACACTGACAGCAACGGCGTTGTGGTGCGAGAATTTCTGGTGGACGAGGGTGACGGTGTGGCTCAGACCATTATTTTGGAGGACTCGACCTACACCATTCTGCCTTTGGAGGAGAATGAATCGAACAACGCCAACAAAACGGAAACCAGCGAGAGTGCGAAGCCCGAAACAAACCAAGTCTCACCGCAGGTCAAGAAGGAACAACGGAAATCATTGGCTGCCAGCCTGGCTGCTGCCATAGCCGACAATCACGAAGAAGTGCTAAGCGATGATGACTTTAGTGGCGAGGTGCTCACAGAAGAGGACCTCAAGCTCAAAGAGAATGTTGCCAAGCTTATCGACATGCTGGTGGATCCGCCCACCCTCAAAAAATACGGCTGGCCCAATACTTCCGAAGAGACTGTACTCTGCAAGGTGATCGAGAACTGCGGCCACGACCTCAACAAGGGCGGCGAGAGCTATGCTGAATTGGACTACGGCTCACGCATGCGTGAATATTGCAAACTCCTGTTCACTGTTGTGATCCACAATGACTCGATTAAATCCTTACTCAACAATTTCCCCATTGACGATGTCATCGAATATGTACTCGGCAATGATGACGAACAGGAGGAGGGCAAAGAACATATGGACTCGGAAGTCAAAAAGGCTGCGGATGCAGCCGAAGCAAAAGCCCAAGCCAAGGCCTAA
- Protein Sequence
- MSKNEKKSTAVEKEKRNASTLQIVDDSQISPAREKRNSSTTTTGTSRIKLLNDAASSGGKASVKQEKRQSTSGGGRIKILNEETLTGKSKSPDKRASISATTKKSATPTSTVKILNDKRVTPAATSVETTKIKTSPTKKKKMDHYVLQSVKSEANKADNTGDGVEDENDEEDNIAFILADDNILESTEARDTASGEEIEEIEEGSDDEAGEASSEIGQQRSTGKNGMKEIVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLDKIEKDALVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSAALLKLHEVQHQIRGKPYACKICGKDFTRSYHLKRHQKCSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCQTCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYSCTVCNQSFAVKEVLNRHMKRHTGERPHKCNDCGKSFIQATQLRTHSKTHLRPFPCDECDEKFKTEKQLDRHMKEHTRQKRSAHMCVPCKKSFRTAELLEEHTKAGKHTPPKPKRPPAKVIERTDCAICDKNFDSTETLRSHIRSVHECNPDDIFGTVAPPPSKRPKRGKKTEAVPDSPDPPGALISSNTDSNGVVVREFLVDEGDGVAQTIILEDSTYTILPLEENESNNANKTETSESAKPETNQVSPQVKKEQRKSLAASLAAAIADNHEEVLSDDDFSGEVLTEEDLKLKENVAKLIDMLVDPPTLKKYGWPNTSEETVLCKVIENCGHDLNKGGESYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGNDDEQEEGKEHMDSEVKKAADAAEAKAQAKA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -