Basic Information

Insect: Saturnia pavonia
Gene Symbol: THAP1
Assembly: GCA_947532125.1
Location: OX383923.1:7400123-7424807[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00028 0.015 16.0 0.4 2 23 411 432 410 432 0.97

2 11 0.75 41 5.2 10.4 1 23 439 462 439 462 0.95

3 11 0.7 39 5.3 3.8 1 23 466 488 466 488 0.95

4 11 0.026 1.4 9.8 3.6 1 23 493 516 493 516 0.97

5 11 0.044 2.4 9.1 1.8 1 23 520 543 520 543 0.94

6 11 0.018 1 10.2 0.0 2 20 556 574 556 576 0.93

7 11 0.74 41 5.2 0.1 2 23 613 635 612 635 0.95

8 11 0.0032 0.18 12.6 1.7 2 23 651 672 650 672 0.96

9 11 1.8e-06 9.7e-05 22.9 3.0 1 23 678 700 678 700 0.98

10 11 2.6e-06 0.00014 22.4 0.9 1 23 705 727 705 727 0.97

11 11 0.019 1 10.2 1.2 1 23 733 756 733 756 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00028	0.015	16.0	0.4	2	23	411	432	410	432	0.97
2	11	0.75	41	5.2	10.4	1	23	439	462	439	462	0.95
3	11	0.7	39	5.3	3.8	1	23	466	488	466	488	0.95
4	11	0.026	1.4	9.8	3.6	1	23	493	516	493	516	0.97
5	11	0.044	2.4	9.1	1.8	1	23	520	543	520	543	0.94
6	11	0.018	1	10.2	0.0	2	20	556	574	556	576	0.93
7	11	0.74	41	5.2	0.1	2	23	613	635	612	635	0.95
8	11	0.0032	0.18	12.6	1.7	2	23	651	672	650	672	0.96
9	11	1.8e-06	9.7e-05	22.9	3.0	1	23	678	700	678	700	0.98
10	11	2.6e-06	0.00014	22.4	0.9	1	23	705	727	705	727	0.97
11	11	0.019	1	10.2	1.2	1	23	733	756	733	756	0.93

Sequence Information

Coding Sequence: ATGATAGTATTGACATTATTGACAGTAGAAGATCTCACCTTTGCCAGACTGCTATCTCGTGTTCCCTCTGAAAGTAAtgttgacagggtgaaaccggcccaTTTGGACGTGACGGCCCCTCGCCGAGCTCCTGAGCCGCCAGCACCTCCTGCAACATCTGCAACACTTACCTCGGCTCCGGACCCTCCTACACCGTTTCCCGTTCCTTCTCCGACCCCTATTACCACTAGAGCTGGTAGGAGAGTACGATTTAGATATAGTTTTCCAATAGACCCTAACATAAAGGAGAAATGGATTGAGGCAACAGGTCGGAAAAATTGGTACCCCTCGAAACCAAGCACTATTTGTTCAAAGCATTTCCACGAGACTGATTTTATTTTTACAAATGGAATTAGGTTTTTAATTGAAGATGCTATTCCGACTCAAGCGATTTTATGCTCTGAGGTTTGCAGAATCTGTTTGGTCTCATGCAACGGGAAAATGTTTTCCTTGAAATTAAATTATTTGAAACAAGCTTACGAAGATCTCATCGGTGTTGAAGCGATCAAATTGGAGGATGAGTACCAGCTACCCCAGAAGCTGTGCTGGGAGTGCGCAGCTCGATTGCTCAGTCACAGCCGCTTCCGAAGCAGAAGTCTCAGGGCGCACTCCATCATGTCGGAGATACTCGACAAACAGCATAATTTGACCAAAGCGAATCTTGCAAGAGTGAATAGAGAGACCAACGAACTCAAGTCATCACTCAAGGCGAAGCATTACGAAGTGAACCATTATGACGTACATATTATATGTGCAGATTATGATGATGAGCTAAAGGAAAATGAAATGGTAGACTTAAAAACAGTAGCAATAGTTAAAGACGAAATGGGAAGTAACGTACACATAGATGAAGATGAACCCAAAATAGCTATATACGTAAATAAATATGATTTCAAAAGAGATGCATCTGAAGATGATGGAGATTTACATGAATCCGATGCGCATTACTTGTCTCAAGTTCGTGTACTATTGGATGAAACTGGGTCAGATGAGAAAGCGGAGCCGAATAAATTAGTTGAAGACAACAAAGTCCAGGTGAAGGAACCGCAGGTAGAATCTACAGTTCGTCCAGGGCAGAAACCGTTTGACCCCAACGAGTTTTATTTCACGGTAACCGAGTTGACCTTCGAAGAACAAGTTGCGGAGTTCGAGAAACGGAAGGAATCATTGAACTACAAGAACGCCGTGTTACGATGCACTGAATGCTACAAATCCTATATAAATGAAGACGCTTACAACAGCCATATGATTAGACATACTGACCAATGCGGCGTATACAAGTGTAGGGTATGCAAACTGCATTTCAAGAAGAATCACGAGCTTCACAGCCACACAAACGCCTGCCACAGAGAGCGGTTCACCTGTAACCAATGCCCCTATACTACAATGAGCCGACACTTGACGAAGAGACACTTTCTCTGGCACAAAGGTGCCAAGTATCACTGTCCTCATTGCCCGCTCGAATTCATAAAATTCACGACTTACATGAGTCACCTAAGGTTGTCGCATCCGTCGGATTTCGTTTGCGAGTTGTGCGGCTTCTCGTTTGTCAGCGCAAAAGGAAAACTTCACCATAAAAAACTGAAACACAAATTCGACAATGCACAAATACCGGATGACGGACCATATTGTGAACTCTGCGATCTGAGATTCATCTCTGTCGAGGCTCTCGAACGTCATCAGGATGTTTCCGCCAGACACAATACAGCAGAAACTGGTAGAGGCAGGGAACCAAACTCTGATCAGAAATTGAGGAAGCACAAGGTAAAGAGGAGAGTGAAGATAGAGGACCCCGTACAGTGTGAACAGTGCAGTATGGTGTTGAAAGGCCCTGTGGCTTACAACGTTCATTTCAAACGGATGCACCCGGATAAGAATCGAACCAACTACCCGACAATCAAAGACCCTTGTATGTGTGAGGAGTGCGGTAAAATATTCAAGAATGAAACGGTCGTGAAATACCACAAGCGGGTGCACACCGGCGAGCGGCCCTTCGTATGCGACCGATGCAATAAATCGTTCCGTACGAAAACGCATTTGATCACGCACATTCAAATCCACGAAGGGAAATCGTATCCATGCGAGCTGTGCGGGAAGAACTACTCGTCACCTAACAACCTACAGCGCCATGTAAATCATCACGCAGGACTGAAGCCTTATACGTGCGAGATATGCATGAAAGCGTTCAAGACGAACACCGAGAAGAAGACTCACGTCACTTACGTACATATGAAGGTACCGTGGCCGAAGAGGAACAGAGCGAGGAGACGCAAGGAGAAAATATACATGGAGTCGAACTGA
Protein Sequence: MIVLTLLTVEDLTFARLLSRVPSESNVDRVKPAHLDVTAPRRAPEPPAPPATSATLTSAPDPPTPFPVPSPTPITTRAGRRVRFRYSFPIDPNIKEKWIEATGRKNWYPSKPSTICSKHFHETDFIFTNGIRFLIEDAIPTQAILCSEVCRICLVSCNGKMFSLKLNYLKQAYEDLIGVEAIKLEDEYQLPQKLCWECAARLLSHSRFRSRSLRAHSIMSEILDKQHNLTKANLARVNRETNELKSSLKAKHYEVNHYDVHIICADYDDELKENEMVDLKTVAIVKDEMGSNVHIDEDEPKIAIYVNKYDFKRDASEDDGDLHESDAHYLSQVRVLLDETGSDEKAEPNKLVEDNKVQVKEPQVESTVRPGQKPFDPNEFYFTVTELTFEEQVAEFEKRKESLNYKNAVLRCTECYKSYINEDAYNSHMIRHTDQCGVYKCRVCKLHFKKNHELHSHTNACHRERFTCNQCPYTTMSRHLTKRHFLWHKGAKYHCPHCPLEFIKFTTYMSHLRLSHPSDFVCELCGFSFVSAKGKLHHKKLKHKFDNAQIPDDGPYCELCDLRFISVEALERHQDVSARHNTAETGRGREPNSDQKLRKHKVKRRVKIEDPVQCEQCSMVLKGPVAYNVHFKRMHPDKNRTNYPTIKDPCMCEECGKIFKNETVVKYHKRVHTGERPFVCDRCNKSFRTKTHLITHIQIHEGKSYPCELCGKNYSSPNNLQRHVNHHAGLKPYTCEICMKAFKTNTEKKTHVTYVHMKVPWPKRNRARRRKEKIYMESN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01316768;
90% Identity: iTF_01317380;
80% Identity: iTF_01317380;