Basic Information

Gene Symbol
-
Assembly
GCA_033032175.1
Location
CM065334.1:4446889-4463838[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.01 1.1 11.0 1.8 1 21 284 304 284 305 0.94
2 13 0.00011 0.012 17.2 0.3 3 23 318 339 316 339 0.96
3 13 0.74 81 5.2 0.1 1 15 376 390 376 396 0.81
4 13 4.9 5.4e+02 2.6 1.5 2 23 403 424 402 424 0.96
5 13 2.7 3e+02 3.4 2.8 1 23 670 693 670 693 0.90
6 13 0.62 67 5.4 0.8 1 23 747 768 747 768 0.81
7 13 0.3 33 6.4 3.7 2 23 814 835 810 835 0.88
8 13 0.00024 0.026 16.2 0.7 2 23 851 872 850 872 0.97
9 13 6.8e-07 7.5e-05 24.2 1.7 1 23 878 900 878 900 0.98
10 13 0.0049 0.54 12.0 0.3 2 23 906 927 905 927 0.96
11 13 0.13 14 7.6 2.7 2 23 934 956 933 956 0.95
12 13 2.4 2.6e+02 3.6 0.2 1 20 963 982 963 983 0.91
13 13 0.00058 0.063 15.0 0.5 3 23 995 1016 994 1016 0.97

Sequence Information

Coding Sequence
ATGGCGGAGCGCAGTAAAATACAAACTCCCCGAAGCAAATTACCAACAAGAAAAGGTTTGGATTCGgaggataaaaatatttacgatttGCAGaatGACATTGATATGcagcttaataatattaaaattgaagtcaTGGATAATGAATATCTAGATGAAGAAGAACTGACAGTCAAATCACCATTACAATTCTCCATCAAAGTGGAAGTTGAGGAATACAGTGACCAatccaataattttaaactggAAGATGACAGAGCCACAGTGTTTTTTCCAGTGACAGAGCATACACCTTGTGAAGAACAAAATCCACCAACTGACTATGCACCAGAGAGATTAGGTGTGGTTAATTCAGAAATTAATAGTAAACCTAAACATAATACATTATACTTATTTGAAGGAGATGAAACAGATATTTGTTTAGAAGCTGATCGCATAGCATTAAACTCAAGCAACATTGTAGATAAAATCCTAGCAAGGGAAGTGAGAAATTTATGTGGAGTACTTGCAAAACCTAATCTTGAAACAACACCATTACATAGACAAATATATACCGTTTACAAAAAATGGAAATCTTGGTGTAACTCAACAAAAATGTATGAACAACCCTTATTTTATAAGTGTTATATATGTGAAAAATCCTGGTGGTATTTAGGACCGTTTGTGGAACACGCAAAAGAACATGCTTTagaagtatatacaatatatctGGAAACAACCAGAACATTTTTGTGTAACATAGTACTGGCTAGTAATGTGTCCAAATCAGAAAAATTCATACACACTGATGGAGACTGCTGGAGGTGTAATAAACCTTATAGCTTCCATGAGAAGACCACTAATCTATGCTACAGATGTAAAGGTTGTCagaaagattttttcaaatgtaGCACATTATGggaacatgaaaatatttgctctaaAATTACACACAGTATGAATAGCATTGACTGCAAAATATGCAAATATGTGTTTGAGTCTTATAATGATTTGGAAAGACATCTTCTTACGAGTCACACTGTTAGGTCAGACTTGTTCATATGGACGTCATACAAGAAATGCTTTATCTGTGACAGGATACATTATAACAACAATGGCAAGACATgttcaaagaaaaattataagttTGTATGTGAATTGTGCTCCAGGAGATTTGCCAGCCAACTCTTGGTTGACAGTCATAAATCATGCACGCAAAGTGATGTACAGTGTGCAGTGTGCGACACAGTACTGCCGAAGCATTGTATGCAGATAAAACACTATATTACCCATACTGACATGTTTAAATTGGTTTGCAAATGTTCCAAATGTACggaagtgtttttgttttggGAGCAGAACTCCATGATAAAGCATCAATGTCTATGGCATAAGAATAAAAGCAAACAAGAATGTTATTTTGAATTGATTTTAATACCAACAAAATGTATTGAAAAACTGAAGGTGGTTAATCCCGAGCCTGTTccattttTTGCGGCAGTGTACGATGATGCGGCGAACAAGGAAACGACAGTGGTGAACGCGTACGAAGATGAACCTGTCACTGAGTATGAAATAAAGCATGAAGTCGTCGATAGTGAGGAAAGTGATGGAGACGTCAATAGATATATCATCGAGGACAGTAACTCCACGTATGATGGAACGACGACAAATATATTCCAGAGTTCGGGAACGAGCAACAGTCAAATAGAAGCTGAAATTAAAACTGAGCTTATGGACTCCAGTGGTGTAGACATGGCAAACATTTCGAGGGACTCAGACGACGGTGAAGAACGACGATTGGTGATGGATATTGGGGAGCACGAGGAAGGCAAGTTCGTTAGAAAGAAGAGACAGAAGAGGGGGCGAGGTGCCTTGTGTTATAAACGTGTTCCCAAGATTTATTCGTGCAGAAGATGCCCTTACCAGGGAATACACAGGGAATATAAGGACCACGTGCTGACTTCATGCATGACGAGTCGTGCAAGGAAATCGATGCTTCAAGGGGAATCGAAATTACATAAACCGCACAAGTGCAGCAGGTGTAAAGTCACCTTCATCTCACTAAACGGCTACCTATATCACTTCGCGAAAAGCCATGGGTACAAAGAGTTCAGCTGCCCGGTCTGTTTCGAAGTAGGCCTGAAAACCAAGTTGTCGTCTCATTTCAATTTCCACGTGAAGCAAATGTTTCTGAAAGTTAAGGCGCTGTCTGCAGACAGTAGTAATAAAACAACTATTATTGCATCGAACGTGCGTTACGAATGTAAAGAGTGCAAGAAGGTCGTCGAGGACACTAACTTCTTCCAACATTGGGAAAGCCATTATGAAGTGAAGAATTTTGACGATATAATGGAAGTTGACAATGTGGAACATATTCTGAACTCGTCGGCGCCTGCacttaatattaaacatttgaTAAGTAAACTTTTGACGCTGCGTTCAAACTACACGTGTCGCACGTGTATGATATGCGATCGGCATTTCAGCAGAGTTAATGATAGTAAACGGCATATCATAGAACACCTCTTAAGCGAtgcttacaaaaacaaatccgGCTACGGGTGTTTGagATGCCAGATATGCCAAGAGATGTTCGAGAAATCAGATGCATACAAGAAACATCTTCGGGAACACGCCTCCCTGCCTATATACAAATGCGGTTTGTGTGACAAATCCTTCAGTGACTCGAGTAACTTcgtgaaacataaaaaaattcataatatcCAAGTTCTAGTCTGCGAtatatgcaaaaataaataccaGGCGAAGTCATCTCTAGAGAAACATATGGAGATACACAATACGACGAAACCGATCACTTGCAAGTTATGTTGCAAGATATTCTACTCCGAGGCGTCCTTCAAGAAACACAGAAGGGCTGTTCACGAAAGGCACAGGGCTAAGTACAAATGCCTTATATGCGAGAACAAGTACACCACCCTGAAAGGCAAGTGGGATCACATGTGGCTGGTTCACAAGGAACGCAAGTTTAAAGCGGACTGTCCGATCTGCCAGAAGGCTTACAGAAAGTTTCAGGACGTGAAACGGCATGTACGTACGGAGCATGGTTCTATCGAAGTGAAGAATGTTATGAGGTTGAGCAACCAGCGTAATGGGCATATTAAGGACTTTTTTAAACATGGCTGCGGTTTAAAGCTTGGTGCTAAGGAGACTCTAATAATTTACGATTGA
Protein Sequence
MAERSKIQTPRSKLPTRKGLDSEDKNIYDLQNDIDMQLNNIKIEVMDNEYLDEEELTVKSPLQFSIKVEVEEYSDQSNNFKLEDDRATVFFPVTEHTPCEEQNPPTDYAPERLGVVNSEINSKPKHNTLYLFEGDETDICLEADRIALNSSNIVDKILAREVRNLCGVLAKPNLETTPLHRQIYTVYKKWKSWCNSTKMYEQPLFYKCYICEKSWWYLGPFVEHAKEHALEVYTIYLETTRTFLCNIVLASNVSKSEKFIHTDGDCWRCNKPYSFHEKTTNLCYRCKGCQKDFFKCSTLWEHENICSKITHSMNSIDCKICKYVFESYNDLERHLLTSHTVRSDLFIWTSYKKCFICDRIHYNNNGKTCSKKNYKFVCELCSRRFASQLLVDSHKSCTQSDVQCAVCDTVLPKHCMQIKHYITHTDMFKLVCKCSKCTEVFLFWEQNSMIKHQCLWHKNKSKQECYFELILIPTKCIEKLKVVNPEPVPFFAAVYDDAANKETTVVNAYEDEPVTEYEIKHEVVDSEESDGDVNRYIIEDSNSTYDGTTTNIFQSSGTSNSQIEAEIKTELMDSSGVDMANISRDSDDGEERRLVMDIGEHEEGKFVRKKRQKRGRGALCYKRVPKIYSCRRCPYQGIHREYKDHVLTSCMTSRARKSMLQGESKLHKPHKCSRCKVTFISLNGYLYHFAKSHGYKEFSCPVCFEVGLKTKLSSHFNFHVKQMFLKVKALSADSSNKTTIIASNVRYECKECKKVVEDTNFFQHWESHYEVKNFDDIMEVDNVEHILNSSAPALNIKHLISKLLTLRSNYTCRTCMICDRHFSRVNDSKRHIIEHLLSDAYKNKSGYGCLRCQICQEMFEKSDAYKKHLREHASLPIYKCGLCDKSFSDSSNFVKHKKIHNIQVLVCDICKNKYQAKSSLEKHMEIHNTTKPITCKLCCKIFYSEASFKKHRRAVHERHRAKYKCLICENKYTTLKGKWDHMWLVHKERKFKADCPICQKAYRKFQDVKRHVRTEHGSIEVKNVMRLSNQRNGHIKDFFKHGCGLKLGAKETLIIYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-