Rfun031908.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Rosalia funebris
Gene Symbol
-
Assembly
GCA_037954035.1
Location
JAZFAV010000019.1:4506974-4516381[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.00034 0.041 16.1 3.2 1 23 341 363 341 363 0.98
2 21 0.015 1.7 10.9 0.3 1 23 372 394 372 394 0.98
3 21 0.0013 0.15 14.3 1.0 1 23 434 456 434 456 0.99
4 21 1.6 2e+02 4.5 4.8 1 23 465 487 465 487 0.98
5 21 0.0068 0.82 12.0 1.4 1 23 496 518 496 518 0.98
6 21 0.037 4.5 9.7 3.1 1 23 527 549 527 549 0.98
7 21 5.3e-06 0.00064 21.8 2.7 1 23 558 580 558 580 0.98
8 21 2.5 3e+02 3.9 6.3 1 23 593 615 593 615 0.98
9 21 0.0022 0.26 13.5 3.8 1 23 626 648 626 648 0.99
10 21 0.0083 1 11.7 1.2 1 20 657 676 657 679 0.94
11 21 0.0086 1 11.7 0.8 1 23 1015 1037 1015 1037 0.98
12 21 0.0012 0.14 14.4 0.4 1 23 1046 1068 1046 1068 0.98
13 21 0.11 13 8.2 3.1 3 23 1079 1099 1078 1099 0.95
14 21 0.0034 0.41 12.9 1.1 1 23 1108 1130 1108 1130 0.98
15 21 0.07 8.4 8.8 2.0 1 23 1139 1161 1139 1161 0.98
16 21 0.00071 0.085 15.1 0.9 1 23 1170 1192 1170 1192 0.99
17 21 0.014 1.6 11.0 0.9 1 23 1201 1223 1201 1223 0.98
18 21 0.035 4.2 9.7 0.6 1 23 1232 1254 1232 1254 0.98
19 21 0.33 39 6.7 0.5 1 23 1263 1285 1263 1285 0.96
20 21 0.0069 0.83 12.0 2.3 1 23 1294 1316 1294 1316 0.98
21 21 0.0062 0.74 12.1 1.4 1 23 1325 1349 1325 1349 0.92

Sequence Information

Coding Sequence
aTGAATGTAGAAGAAAAACACATTTGCAGATTGTGTTTTGACGTAACAAATGatgaatttaatgaaatagaTGATATTATGGGCGATATGTTGGAAGTGCTGTTATTAGAAATGGATTTGAAGATAACTGAAAGCCCTGTTATATGTGAGACTTGTACAGGAATCATCACAggattgttatattttaaattggtcTGTCTCCATAacgaaaaacttattttatcttTTGCCATTAATGAAAAAGAAGCTAAATTTGAATTGATGGATGTAGTCCGTAAAAAGGGAGATTCAGAAATGGCGGttgaagaaaatttcaggtgtCGTTTCTGTATGAATGGGataaaaaataacgattttGTCTCTATAGACATTTTAATGGAGGAAGCATTGTATAAGGATACATTACCAGCATTTATGCCAGAAATTGACTTCAGCCTAGTCAAGAGTCCCATAGTTTGTACTTCTTGCAAGGAAAATTTAGACTATTATTTCAAGTTAATAAAGGATTGTTTGAATGTAGAAAACcaaatacataaattttgtCAACATGGAGAGAATAGTAGATCAGGAAATGAACATTCCAATGTATTACGTTTTCTGTGTCGTAGTAACTATGTACGTAGTCGCTTCAGGGCTGAGAAATGTACATGGACACAATCTGACAAACGGGAAACAACTACATCTGAGTACTCATGCCAATTAACGCAGGCTGAAGAAATATTGGAGATCAAAGATGACGGAGAGTTGTTAAATGAGGATTCTTGTGAACGTCGATCACTAAATGGCGATAGGTATTCCTATAAGGGAAATTATAACCTTTTGCAAACTAGTATATGTTCAGAAAGTGATACAAAcagttgtaatatatttactgaTAAGACAAAACAGACACAATCTCGGGAGAGGAATACAATAGATAAACTAAATCACAAGTGTATACTGTGTAATTACACAGAAAAGTGCAAACATTTAGTGCGGGAACACATGCTGAATCACAAGGATCCTTCAGAAGCGGACATGTACAAATGTTCACACTGTCCCTATAGGACTAAGCGGGAAGGCTATCTTAAACAGCATATGCTACTCCACACGGATGCCTCAGAAGTAAAAACTTACAAATGTGACTCGTGTGCTTATGTGACAAAGTACAAAGGTGCATTACAACAACACGCGTTAACCCATAAAGATGCGTCTGAAGTAGAAACGTACAAGTGTTCACGTTGTCTCTACGAGACCAAGTGCAAGCGCTACCTAAAAGGTCACATGTTAGTCCACAAGGACGTCTCGGAAGTAGCAATGTACAAATGCGAATTCTGTACGTATGCCACCAAACTCAAAGCTAACCTACAACGACACGCGTTAACCCACAAAGATGCATCTGAAGTAGAGACGTACAAGTGTTCACGTTGTCTCTACGAGACCAAGTGCAAGAGCTACCTAAAAAGTCACATGTTGGTCCACAAGGACGTCTCGGAAGTAGAAATGTACAAATGCGAGTCATGCACTTACACTGCGAGAAATAAATATAGCTTACAACAACACGCGTTGAGCCACAAGGGCGTGTCTGAAGTAACGATGTATAAGTGTTCGCTATGTTCATACGAGACGAAATGGAAGAGCCACCTTAAGAGGCATATCGTCAGCCACAAGAACGCTTCAGAGCTCGAAATGTACAAGTGTCCGCTATGCGATTATCAGTTCAAACACAAAGAGAACATGAAGCGTCACATATTAGTCCACAAGAATCGTTCCGAACTGGAATGCACAACTGAGATGCACAAGTGCACAAGGTGCGCCTTCGAGTCGAAATACACAGGCTGTCTGAAGAGGCACATGCTTACCCATCTCCAGGCTAGCTCTTCGGAAATAACGACGTACAAGTGTCCAACGTGCCCTTTTCAGACCAGACATAAACGTAACATAAAACAGCACATGTTAACCCATAAAGAAGGATCGGAATTGAAGATGTACAAGTGTTCGATGTGCCCCTTCGAGACGAAATATAAAGGTAACTTGACGAAACACGTGCCTAAACACACCTATGGGAGTGCCCAAAAACTATGTTTAAATATGAATGataatgaaattgataaaatagaTGAAATAATGAGAGGAATGCTAGAAGTTCTCTTATTAGAAATGgATTTTAGTATAACTGAAAAACCTACGACATGCAGGACCTGTACAGGCATTATCAAACGATTATTTTACTTCAAATCGGCCTGCATCTGCACTGAAAAACTTTTAGTTTCTTTCGTTGTTAACCTAGACGAGACCGAATTTGAAATCAAGGACATAGATCATGACAAGGGATGCATAGAAATGGTAGTTGAAGGAAGTTTCATGTGTCGATTTTGTATGAATAGGataaacagaaataattttgtgCCTGTAGATATTTCAGTGGAGGAATCAATGTACAAGGAGATGTTACCAGTATTTATGCCAGAAATGGATCTCACCATAGTCAAGGTTCCTATAGTTTGTACGCCTTGTAGAGAAAATTTAGAATGTTATTTCTTGTTCATAAAGAACTGTTTGGGCATAGAGAACGAACTATATGAGTATTGCCAAAATGCAAGTAGTAACCGATCGGGTAGAATTAAATTAGCCGatgtatttcattttctatttgaTGATAACTCAAGACAATTCGATAAATATGCAGGAACCCATCCCATCAAAAGCGAATTAAAATCCAAAGAGCTATTATACTCTCGTGATTTTATGAACATTGGAGAAATATTGGACGCCAATGAACAAATGTGGTTAAACAATGACCCTCGTGAAAGTCTTTCAGAAATAGGATTAGACAATGAGAGGTACCCCTATGGGCAAAATAAACTTGCACAATCTAGCGTACATTTGGATATGGATATGTATAGTCAATACACGCCTACTAGTGGAACAGAACAGAGCCAGTATTGCAACGGGAATGAGACccccaaaaataattcagacaaaTGCAAAAGTTTGCTGTGTCCAAACGTTGCAACATACAAAAGGGCATTAAAAGACGAGGGTGGTTCAAAAGTAGACATGTATGAGTGTTCACATTGTCCCTACAAGAGTGGTGTGAAGTCCAATATTAAACAACATATCTTAGTCCATAAAGATGtctcagaaataaaaatatacaagtgCGGATTGTGTACTTATGCGACGAGATACAAATCCGCGTTAAAAGCCCACTGGCTATCCCACAAGGATCTCTCCGAAGTAGATATACAATTGTGTCCATGTTGTCCATACAAGACGAAGGTAAAGGGCCATCTTAAGAAACACATGTTGGTCCACATGGACGCCTCGGAAGTAACGATGTATAAGTGCGAATTGTGTCCGTTCGTGACAAAATACAAATCTGCTTTACATGAACACGCGTTGACTCACAAGGATGCTTCAGAAGTAGACATGTATAAGTGCTCGCTTTGTCCATATGAGACCAAATGGAAGCGCCATCTCAAAAAGCACGTGATAATCCATCAGGACGCCTCCGAAGTCGATATGTATAAGTGCTCGGATTGCCCGTATGAGGCCAAGTTAAAGGGCAACCTGCACAAACATATGTTAGTCCACAAGGACATTTCAGAAGTGAAAATGTACAAATGTGAATTATGTAGTTACGCGACAAAGTACAAAAACTCGTTACGAGGACACGCGTTGACTCACAAGGACACCTCTGAGGTGAAGACATTCAAGTGCGGATTGTGCACGTTCGTGACGAAATACAAACGTGCTTTGGAGCTGCACGCGCTGACTCACAAGGATGtctctgaaataaaaatatataagtgcTCGCTTTGTCCATACGAGACGAAGTGGAAGAAGCAGCTGAAGGAGCATGGCCTGATCCACAAGGACGAGTCGGAGGTGGAAATGTACATGTGTTCGGTATGCAATTTTCAAACTAAACGTAAACGTTACGTCAAAGTGCACATGTTAACGCATAAGAGGGCGTGGGAATTGGAGACGTATAAGTGTGCAGTGTGTGCGTTTgagacaaaatataaaagtaacctGATGAAGCATATGCTCAAACGCTCCCATAAAGTGTCTCAGAAGTAA
Protein Sequence
MNVEEKHICRLCFDVTNDEFNEIDDIMGDMLEVLLLEMDLKITESPVICETCTGIITGLLYFKLVCLHNEKLILSFAINEKEAKFELMDVVRKKGDSEMAVEENFRCRFCMNGIKNNDFVSIDILMEEALYKDTLPAFMPEIDFSLVKSPIVCTSCKENLDYYFKLIKDCLNVENQIHKFCQHGENSRSGNEHSNVLRFLCRSNYVRSRFRAEKCTWTQSDKRETTTSEYSCQLTQAEEILEIKDDGELLNEDSCERRSLNGDRYSYKGNYNLLQTSICSESDTNSCNIFTDKTKQTQSRERNTIDKLNHKCILCNYTEKCKHLVREHMLNHKDPSEADMYKCSHCPYRTKREGYLKQHMLLHTDASEVKTYKCDSCAYVTKYKGALQQHALTHKDASEVETYKCSRCLYETKCKRYLKGHMLVHKDVSEVAMYKCEFCTYATKLKANLQRHALTHKDASEVETYKCSRCLYETKCKSYLKSHMLVHKDVSEVEMYKCESCTYTARNKYSLQQHALSHKGVSEVTMYKCSLCSYETKWKSHLKRHIVSHKNASELEMYKCPLCDYQFKHKENMKRHILVHKNRSELECTTEMHKCTRCAFESKYTGCLKRHMLTHLQASSSEITTYKCPTCPFQTRHKRNIKQHMLTHKEGSELKMYKCSMCPFETKYKGNLTKHVPKHTYGSAQKLCLNMNDNEIDKIDEIMRGMLEVLLLEMDFSITEKPTTCRTCTGIIKRLFYFKSACICTEKLLVSFVVNLDETEFEIKDIDHDKGCIEMVVEGSFMCRFCMNRINRNNFVPVDISVEESMYKEMLPVFMPEMDLTIVKVPIVCTPCRENLECYFLFIKNCLGIENELYEYCQNASSNRSGRIKLADVFHFLFDDNSRQFDKYAGTHPIKSELKSKELLYSRDFMNIGEILDANEQMWLNNDPRESLSEIGLDNERYPYGQNKLAQSSVHLDMDMYSQYTPTSGTEQSQYCNGNETPKNNSDKCKSLLCPNVATYKRALKDEGGSKVDMYECSHCPYKSGVKSNIKQHILVHKDVSEIKIYKCGLCTYATRYKSALKAHWLSHKDLSEVDIQLCPCCPYKTKVKGHLKKHMLVHMDASEVTMYKCELCPFVTKYKSALHEHALTHKDASEVDMYKCSLCPYETKWKRHLKKHVIIHQDASEVDMYKCSDCPYEAKLKGNLHKHMLVHKDISEVKMYKCELCSYATKYKNSLRGHALTHKDTSEVKTFKCGLCTFVTKYKRALELHALTHKDVSEIKIYKCSLCPYETKWKKQLKEHGLIHKDESEVEMYMCSVCNFQTKRKRYVKVHMLTHKRAWELETYKCAVCAFETKYKSNLMKHMLKRSHKVSQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-