Rfer017227.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Rhynchophorus ferrugineus
Gene Symbol
zfh1
Assembly
GCA_014462685.1
Location
JAACXV010000032.1:689053-719510[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.016 1.2 10.0 2.4 2 23 162 184 161 184 0.93
2 9 0.0015 0.12 13.3 0.2 3 23 215 235 213 235 0.95
3 9 2.9e-05 0.0023 18.6 1.0 2 23 242 263 241 263 0.97
4 9 1.7e-06 0.00013 22.5 5.9 1 23 272 294 272 294 0.99
5 9 0.00014 0.011 16.5 1.0 1 21 300 320 300 321 0.95
6 9 0.018 1.4 9.8 0.2 2 19 563 580 563 580 0.96
7 9 4.3e-06 0.00034 21.2 1.4 1 23 915 937 915 937 0.95
8 9 0.00017 0.013 16.2 9.4 1 23 943 965 943 965 0.98
9 9 0.0019 0.15 12.9 5.0 1 21 971 991 971 992 0.96

Sequence Information

Coding Sequence
atggTGCGGATTTTCCAGATCGCGAGCGATGGAAAAAAAGAGGGAAAAACAAAAGTTGAGTATTTGCGAAGTAGGCGCCGCGACAGGAAAAATTCCCGAACGGTACGGCGTGTGAGCGGGCGTCATGCCCACGGTCGTTCCAAGATCGGCGGGCCGAGCGTAGCAGCAGCGTCCGAGACGATCCGGCTCGGGGGTGGGGAGAGCTTCGCCGGCGTCATCCTCGCGACGGCGGTGGTGGGGATGACGCCCGTCGTCACCGTAGCACGTACAACATCGCACAGTGCACGTCCTGAGTTTGGGTCGGTGCGTGGCACGGAGTCTCATTCGGCCATGGTTGCGCGAAGTGAGAACATGTTTAGTTACGACAGTTACTCCTACCGGCTCTGGAGTTTAGCCAATGTCTGGAACACCTGTCAACCTCCGCTGACAAACGGAAGCCTCAAAGAAGTTGAAGACCTCAACACAATCCCCGAATATTTGATCAAGTGCCCCCATTGCCAGAAAGGATGTCAGAGTTTCTCGGCGTTGAAGGAGCACACGGAGCTCGTGCACACCGAACTGACAGCTTCGTCGGAGACCAGCATGTCAGTTACCAGTGCCGTCTCCCCAACCCCTCTGGGAGGGCCCGGTGGTCCTTACGGATGCACCCAATGCAGCGCGTCCTTCGCATCGAAAGAACAATTAGAGAAGCACGAACTATTACACTCACCGAACGCTCAAGTGTCGTGTAAAACGTGCAACAAAACCTTTGCCAATGTCTATCGGCTCCAAAGGCACATGATCAGTCACGACGAGAGCGCAGTACttcgaaaatttaaatgtaCCGAGTGTGATAAAGCTTTCAAGTTCAAACATCACCTGAAGGAACACATACGCATTCATAGTGGCGAGAAACCCTTCGAGTGCGTCAACTGTGGAAAGCGATTTTCCCATTCGGGGTCGTACTCCAGTCACATGACGTCAAAAAAATGTTTGGTGATGAACCTGAAGCAAGGTCGAAACCGAACGCTCTTAAACAGCAACATTCTGGATAAGAACGTCCAACAAGGTCTTAAGGGACCGAAAAGAACTTCAGTCAGTTCCATCAACAACAACATCACGACTAGTCCCAATCATAACTCACCGTTCATGCCGATCTTACCCAAGTACTCTGAAGCTGCGGCTGCTGCGGCTTTGTTCCAGTCCCAACTCGCCAGTAACGCATCGGTGTCTCCTTACTATTTAACACCGCACAGTCTCTTAAACTCTGGACATCCGATGAACGCGTATGTACCAAACATCGGGCATATTCTTGAACAGTTCCATCAAAGAAACGCCAACGCAATAAGCAACGCCCTGATGGACACGTCTGAAACGAAAATGTCTGAAGAGTCTTGTAAACAAGAAGAGAAGACCAGCACGATAAAAAGGGAATCCCACCAAAGACCTGACGATTTCGACGACATGTCGAAATCCAACGCGTCTGAATGCGGTGATTTGGTCATGGACGAAGATGCGGATAATCAAAGCGCAGAACTAAACAAGACCGAGGAGAAAGTCTCGGAGAAACCCGAGTTTAAAGTGTTACAGCACGAAGAACCGAATTCTTCGCAGGAAGAAAGGACGTCTGACGCAAAAAACCATGAGGAATCACCTAATAATGTTGAGAATGAATCGTCGCAGGAACCATCGCAAGAAGATTGCAGAACCTGCATGCATTGTAACAAGATCTTTAATTCTGCGGCGCTGCTTGAAGAGCACGATTGTAAAGACACTCAAAGCGAGGGTTTGGCTGCGAAATTAGAAGCTGCCTTAACGCCAAAGTCTGATAACTGTTCCAACGAAAACATGAGCGGCGGCGAGGATCATGACTTCGAAAGGTCCAGCTACCACACAAACGACGAGATGGATTCAGAAAATTACACAACAACAGATCACGTAAACGAAGACGGGAGAAAGGTGCGGGTTCGATCGCTGATCTCCGAAGAGCAGCTAAAGATACTCAAGGACCACTACAAGAACAATCCGAGACCGAAACGGGAAGATCTCGAAAAGATCGCGGGGAGCATTGGGTTCCCCGTCAGGGTGGTGCAGGTATGGTTCCAGAATACCAGAGCGCGAGATCGACGGGAGGGGCGCTTGATTCCAGTTCCTTACAGTCCAATAGCATCAGGGTCTCGATATTCCGTGCCTTCAACTCCCTTAACCTACCCGGTGATGTCCAACGAGGACATCTCGGAGCAACCTCTTGATTTATCCGTTAAGAGGGACGCGAACTCGAACGAGACGTCTCCGTCGTCCTCTCCGAAACGGCCTCATTCAGTCAGTCATTCCGAATCCCATGACGAAGTCGTGAACTTAAGTCATAAGTCATCCAGGAGCCCCACTCCCTATTTGCCTTATCACAATAATTTCCACTCAAACTCGTCAGATCCAAGTCAGTCGCCTTCTCCACTGGAATTTAACAGTAGTCGGCTGGCGCAAATCTTTAACCAGCCCGCTCACAAGTTAACAGCCTTGCCCAATATGAGTTTGGTTCCCATGGATCAATTGATGCATTTCGGCACGCCCGATTTATCCCTCAGCTTATCCCAGTTCATTAACAGTCGAATGTCCAGCTTAAGTCCAAATTCGACGCATTCTCTGCATGATTCCGCACAGGAGGACGACATGATTCAGAGTAGGCGACATAAAATTCCACCGTTCATGTTAAAGAACATGAATAGTCCAGCTTTAAGTCAGGAAACGGAAGTGGAAGGGCAGTTTCAATGTGATCAATGTGATAAGGCGTTCTCAAAACAAAGCTCCCTGGCGAGGCATAAATATGAACATTCTGGTCAACGTCCACACAAATGTGATGAATGTCCAAAAGCTTTCAAACATAAGCACCACCTCACTGAACACAAGAGGTTACACTCTGGGGAAAAACCTTTTCAGTGTAAAAAATGCCTGAAGCGATTCTCCCACTCTGGTTCATTCAGCCAACATATGAACCATCGATACTCTTATTGTAAGCCTTACAGAGAATAA
Protein Sequence
MVRIFQIASDGKKEGKTKVEYLRSRRRDRKNSRTVRRVSGRHAHGRSKIGGPSVAAASETIRLGGGESFAGVILATAVVGMTPVVTVARTTSHSARPEFGSVRGTESHSAMVARSENMFSYDSYSYRLWSLANVWNTCQPPLTNGSLKEVEDLNTIPEYLIKCPHCQKGCQSFSALKEHTELVHTELTASSETSMSVTSAVSPTPLGGPGGPYGCTQCSASFASKEQLEKHELLHSPNAQVSCKTCNKTFANVYRLQRHMISHDESAVLRKFKCTECDKAFKFKHHLKEHIRIHSGEKPFECVNCGKRFSHSGSYSSHMTSKKCLVMNLKQGRNRTLLNSNILDKNVQQGLKGPKRTSVSSINNNITTSPNHNSPFMPILPKYSEAAAAAALFQSQLASNASVSPYYLTPHSLLNSGHPMNAYVPNIGHILEQFHQRNANAISNALMDTSETKMSEESCKQEEKTSTIKRESHQRPDDFDDMSKSNASECGDLVMDEDADNQSAELNKTEEKVSEKPEFKVLQHEEPNSSQEERTSDAKNHEESPNNVENESSQEPSQEDCRTCMHCNKIFNSAALLEEHDCKDTQSEGLAAKLEAALTPKSDNCSNENMSGGEDHDFERSSYHTNDEMDSENYTTTDHVNEDGRKVRVRSLISEEQLKILKDHYKNNPRPKREDLEKIAGSIGFPVRVVQVWFQNTRARDRREGRLIPVPYSPIASGSRYSVPSTPLTYPVMSNEDISEQPLDLSVKRDANSNETSPSSSPKRPHSVSHSESHDEVVNLSHKSSRSPTPYLPYHNNFHSNSSDPSQSPSPLEFNSSRLAQIFNQPAHKLTALPNMSLVPMDQLMHFGTPDLSLSLSQFINSRMSSLSPNSTHSLHDSAQEDDMIQSRRHKIPPFMLKNMNSPALSQETEVEGQFQCDQCDKAFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCKKCLKRFSHSGSFSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00376140;
90% Identity
iTF_01307133;
80% Identity
iTF_01307133;