Basic Information

Insect: Rhynchophorus ferrugineus
Gene Symbol: topi
Assembly: GCA_014462685.1
Location: JAACXV010000267.1:2157-16769[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0036 0.28 12.0 3.0 2 21 93 112 92 113 0.94

2 14 2.6e-07 2e-05 25.1 0.5 3 23 152 172 150 172 0.96

3 14 0.065 5.1 8.1 0.6 2 23 178 199 178 199 0.95

4 14 0.22 17 6.4 0.1 2 13 218 229 217 230 0.89

5 14 3.9e-05 0.003 18.2 1.7 2 23 263 284 262 284 0.97

6 14 0.059 4.6 8.2 0.1 1 20 290 309 290 311 0.88

7 14 0.062 4.9 8.1 2.6 2 21 327 346 326 350 0.84

8 14 0.9 70 4.5 2.1 1 23 453 476 453 476 0.93

9 14 0.036 2.8 8.9 1.2 1 23 480 502 480 502 0.92

10 14 7.4e-07 5.8e-05 23.6 2.4 1 23 508 530 508 530 0.98

11 14 0.02 1.6 9.7 0.2 1 23 536 561 536 561 0.96

12 14 0.13 10 7.2 3.3 1 23 567 589 567 589 0.86

13 14 3.7e-05 0.0029 18.3 0.5 3 23 597 617 595 617 0.97

14 14 6.9e-06 0.00054 20.6 0.9 1 23 623 646 623 646 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0036	0.28	12.0	3.0	2	21	93	112	92	113	0.94
2	14	2.6e-07	2e-05	25.1	0.5	3	23	152	172	150	172	0.96
3	14	0.065	5.1	8.1	0.6	2	23	178	199	178	199	0.95
4	14	0.22	17	6.4	0.1	2	13	218	229	217	230	0.89
5	14	3.9e-05	0.003	18.2	1.7	2	23	263	284	262	284	0.97
6	14	0.059	4.6	8.2	0.1	1	20	290	309	290	311	0.88
7	14	0.062	4.9	8.1	2.6	2	21	327	346	326	350	0.84
8	14	0.9	70	4.5	2.1	1	23	453	476	453	476	0.93
9	14	0.036	2.8	8.9	1.2	1	23	480	502	480	502	0.92
10	14	7.4e-07	5.8e-05	23.6	2.4	1	23	508	530	508	530	0.98
11	14	0.02	1.6	9.7	0.2	1	23	536	561	536	561	0.96
12	14	0.13	10	7.2	3.3	1	23	567	589	567	589	0.86
13	14	3.7e-05	0.0029	18.3	0.5	3	23	597	617	595	617	0.97
14	14	6.9e-06	0.00054	20.6	0.9	1	23	623	646	623	646	0.98

Sequence Information

Coding Sequence: ATGAATTCTACTATCGTGATTCTTGTGCATAAAATCGTGGATAACCAGATAGTGTCGACAATACGAGATGAGAAAAATTTAGCATTCGTTTCAGATATGGTGATGCGAACTTATCTGAACCCCGAGCAGTTCAAGTTCGATTTTTCTCGGTATAAATCTGAAATGTTGAATCTGAATGTGGACTTATTTGATCAAGACGAATCACTGACGATCGAAGCTTTAACTGAGAATAACAATTGGCAGCGTGCAGTAAAATTAAACTTCCCGACATTAACAAAGTGCCAAAATTGCGAAACAAATTTTccaacaaaatatcaatatcaaagaCATCAATGTGATTTCAATGCAGATAAAGTAGTGTTTAAATCGAGCCCCGAATGTTTGCTTGTTAGCGACACTGCAATTACTGTTAAAGAACAGGATATATTGGAGGAAAACAAAGAAAACTTAGACTGCGAGGTATGTAATAAGAGTTTTGCTAATAAGGGAAATTTGGAGAGGCATCAAACAACGCACGTAGGGCAAGAAAATGTGTGCGAGTTCTGCGCAAAACGTTTTGTAAGTGAAAACCGTTTGCGCATCCATAAGGAGAATCATTGTAAAAAAGCAGGCGACGTTGCCAAGTTTTATCGCAGTGACGTAACGGTGTGGAAGTGTCAGATGTGCCATGAAGTATTTTCTTCTGCCGATATTGGTGCTTATCATGCTTCAATATGTCAGGAGTTTTCCAATAAAGAAGAATCGAGCGAAACCACCATTGAAAAAATTTCCACAGAGGTTTTGCTGCAGTGTGAATTTTGTAATCGCACATATTCGGATAAGAACCTTTTGTTAATGCACCAACGCAAACATACTACGGCAAAGAATTACGAATGCGTCAATTGTAATAAAGCATTCGATTCGTTTTCCGCGGCATCAGTTCATTGGCTAAAACGTTGTTCGGAATTTTCTAACATTTTCTACTTGCCTCGGTTATCGTATTGTGAGTATTGTGATCGCACATTTAAATCCCACGAGATATTATACAACCACAAGATTAAAAAGAAGCACTACACACCCAAACTGCATTGCATGGTCGACGCAGAAGATCGTACTGATAATGTTGATCGAGTATCTGTTCTGGGAAACAAGGATATagtgaataaattaattgaagacGTGCTGAAAACTTTGGAGGTACCTGTAAAAGAAAACCAAAGCAGAGGGGATCTAGTGGATATTAAAACTGAACTCGAAAGTGACAATAATAGTAACAGTTCTCCAGAAGagtataaaatatcgaaaaaacgtaaaatttcACGCGCGGTACCAGGAAAAAGCAAGAAATTGGCGGCTTCGACCGATGAAGGGTTCAAGTACCAGTGTGAGCGCTGTATTAAAGTGTTTAGTTGCGTGAACAATTTAGAGAATCACAGGACTCAAGAGCATGCAGCCAGTTTTTGTTGTGATGAATGTGGTCAGACGTTAGCGTCTGCTAAGGCTTTACTGATCCACTGCAGAGCACACAAGAGTTTGAAGCCGTACGTTTGTGACACTTGCGGTCGGAGTTACTCACAAACTTCTCATTTGTGGCAGCACATGAGATTTCATCAAGgaataaaaccatttgcgTGTCCCCACGAAGGTTGTGAAGCCAGATACACCATCAGACCGGATTTGAAGGATCACATTCGTAAAGTCCATACCAGAGAGCGCCCTTTCAAGTGTAATGTATGCAACAAGTGTTTCCTGACGGGATCTGTGTATTACCAACACAGATTAATCCACACCAATGACCGTCGTTACGGATGTGAGATCTGCAGCAAGAGGTTTTTCAGGGCGGATGCTCTGAACAACCATAAGAGAATCCATACGGACGAGCGGCCTTATCCTTGCTCGGTGTGCGGTCGACAGTTCCGCCAGAAAGGCGATAGAAACAAACACGTGCGCACTCAACACCCGGATTATCCCGCAATTTGTTTGTAA
Protein Sequence: MNSTIVILVHKIVDNQIVSTIRDEKNLAFVSDMVMRTYLNPEQFKFDFSRYKSEMLNLNVDLFDQDESLTIEALTENNNWQRAVKLNFPTLTKCQNCETNFPTKYQYQRHQCDFNADKVVFKSSPECLLVSDTAITVKEQDILEENKENLDCEVCNKSFANKGNLERHQTTHVGQENVCEFCAKRFVSENRLRIHKENHCKKAGDVAKFYRSDVTVWKCQMCHEVFSSADIGAYHASICQEFSNKEESSETTIEKISTEVLLQCEFCNRTYSDKNLLLMHQRKHTTAKNYECVNCNKAFDSFSAASVHWLKRCSEFSNIFYLPRLSYCEYCDRTFKSHEILYNHKIKKKHYTPKLHCMVDAEDRTDNVDRVSVLGNKDIVNKLIEDVLKTLEVPVKENQSRGDLVDIKTELESDNNSNSSPEEYKISKKRKISRAVPGKSKKLAASTDEGFKYQCERCIKVFSCVNNLENHRTQEHAASFCCDECGQTLASAKALLIHCRAHKSLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCNKCFLTGSVYYQHRLIHTNDRRYGCEICSKRFFRADALNNHKRIHTDERPYPCSVCGRQFRQKGDRNKHVRTQHPDYPAICL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00376594;
90% Identity: -
80% Identity: -