Rexs014639.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Rhorus exstirpatorius
Gene Symbol
znf423
Assembly
GCA_963564615.1
Location
OY751318.1:22477289-22497798[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 9.4e-06 0.00093 19.9 1.5 1 23 97 119 97 119 0.98
2 20 0.23 23 6.1 4.9 1 23 125 147 125 147 0.98
3 20 1.2e-06 0.00012 22.7 4.1 1 23 153 175 153 175 0.99
4 20 0.00025 0.025 15.4 0.2 1 23 181 203 181 203 0.99
5 20 5.8e-05 0.0057 17.4 0.5 1 23 367 390 367 390 0.97
6 20 0.29 29 5.8 0.0 2 23 401 423 400 423 0.88
7 20 0.24 24 6.0 0.1 3 23 493 513 492 513 0.97
8 20 0.0032 0.32 11.9 0.1 3 23 529 549 528 549 0.96
9 20 0.0064 0.63 11.0 3.9 1 23 558 581 558 581 0.94
10 20 2.6 2.6e+02 2.8 0.1 1 23 586 609 586 609 0.91
11 20 4.6 4.5e+02 2.0 0.1 9 23 640 655 638 655 0.94
12 20 0.6 60 4.8 2.1 2 23 683 704 682 704 0.96
13 20 0.0023 0.23 12.4 0.1 1 23 709 732 709 733 0.95
14 20 3.9 3.8e+02 2.2 0.3 3 23 802 824 801 824 0.84
15 20 5e-05 0.005 17.6 1.0 2 23 840 862 839 862 0.96
16 20 1.2 1.2e+02 3.8 0.6 1 12 871 882 871 894 0.76
17 20 0.0046 0.45 11.5 0.1 2 23 1107 1129 1106 1129 0.95
18 20 0.055 5.4 8.1 0.7 1 23 1139 1162 1139 1162 0.96
19 20 0.11 11 7.1 0.2 2 23 1205 1227 1204 1227 0.93
20 20 0.21 20 6.3 1.8 1 23 1234 1257 1234 1257 0.95

Sequence Information

Coding Sequence
atgCTGTTCAAAGGCAATAGTTCGCGATTGGAATTGCTGATCGGTAAGATTCAGGCGCACAAGGAATCACCGTCGCCACCTCGAGGTGACAAATGCACTCCCAGATCCAAAGATGCACTGGGCACCGGTAGCTCATCTTGGCACAGCGAGGATGGCGGAACGAATTCACGACGCGGCGGGGAAACTCCATCGTCATGCGCTACTCCAACGTCAGCGAGTTTTCCATCGGAACCGGAAGTGGATGCAGAAATCGGCATCAATGCCGATGGTAACAATCCCGCAGCGCCATATCCGTGTCAGTTTTGCGACAGAACTTTTCCACGGCTCAGCTACTTGAAGAAACACGAGCAGAGTCACGGCGACCAAATGCCGTATCGTTGCAGTTGGTGCTCGCGGCTATTCAAGCACAAGCGAAGCAGAGATCGTCACGTGAAGCTGCACACCGGGGACAGAAGATACCGTTGCTCTCATTGCGAGGCTGCGTTCTCAAGAAGTGATCATCTGAAAATTCACATGAAAACCCACGACAACCAGAAGCCTTATCAGTGCACAGCGTGTTCGCGCGGCTACAATACCGCGGCGGCCTTAACATCGCACATGCAATCGCACAAGAAGCACCCAAATTCGAATCAGAATCCGAAATTGGACGTTGATTATGGGCGCCGAAGTGTTTCGTCGCACAGCACTTCGTCGCCGCCCATACAAAATTCCCCATCCCCAAGCTTGAATCTCAGTCTGAAtctgaaaaattcattgaaatccCAACCATCGATTCATAACAATGGCAACGGTGGACCTAAGACACCAGTTCTAAATTCACCGTTGAAGCTCGCCTGCATGTACTGCACCAAGGACTCATTCACGAGCATGCAACAATTGCAGTTGCATGTTCATGCGATGCATCAGGCGATACTCAACGGCGAAAGTCTGAGCATGGAATCATCGGGTCAAGCAAAGCCGGAGGCAAGCGATACGAAGTGCCGGGATCAGCAGCCGACGATGGAAGGAAGCGTCAGCAATGAATACGACAGAACGTGTCGTCACGAGGGACGCGAAAAGTTCACGGAAGCAGACAGAGGGAGTTCGTTGGATAATGGATTTTCCTGCGGTCAGTGCACAATGAGATTCTCGAATCTCAGCGAGCTGCGGGATCATCTGCTGACGATACATCGCAACGACGGTTTCGGCACTGCCCTGATGATGTGTCCTCTGTGCGGTATTCCATGCGCCTCCGCTGCCTCTTATGCCGAACACTATGTGCTCCAGCATTGCGATAATCATCGTTTAACGACGAAAGATTCGCGGCATCGCGACTGGGACTTGACAAAAACAAACGGCAGTCGGGAAAGCAGCCGTCCAGGCTCGGAGGATCACGCTGTGACGAGCAGAAACGATCACGGAACCTCCGAAGCCGCGGATCTGACGAAGAAACACTCGAGACCCGGTGATACCGGTTACACAAGCGGTACTCTGCTCTGCGGTCAGTGCGGTGCCGCACTGAGGGATTTCGAGTCATTTCGCGAACATCTGGCTCGTCATCTTCAGGCTGATCAGCAGAGCGGCGAAGTCCTACCGAGAAATCCGTGCCCAAAATGCGGCACAAATTTCCCGGAACGCGAGGACATGCTGGCGCATCTTACCAAGCACTATCTCGGCCAGGTCACCAAGGAATATACCTGCGGTGCTTGCAAAAAGTGTTATCATCATCCTGACCTGCTGCAGCGACATCTTCTCGATGCCCATGCTCATCATCTCTATCGCTGCGCCGTCTGTCGCGATACGTTTGATTCGCGAGTCGCCATACAGGTACACTTTGCAGTCAAACACAGCCAGGAGTGTCAGGTGTATCGTTGCAGCGTTTGCAGTAGTTCGAGCAACGAGAGTTCACCGGACACCTCGCCCGTTGACggtaaaaattgttttcgaaGCGAGGCAGAGATGGCGAATCACGTTAGAACGATTCATGCACCTCGTACGGTCATCGGTGCGAGTCCTACGCGAAAAAGTCCTGCTCCAACGACGGTCACCACCATGACCACCAGTTCCAGATGCGTTTTCTGCGGCATCTGTTGCAACACGGACCTGGAACTGCAGCTTCATCTGGCGAGTCATTCGACCAGCCTGTATCGTTGCCCAATTTGCAGGGAGGGTTACCCCGTTGAATTTTTGTTGGAGAGGCATATGGCGCAGGCGCATCATAGAAACGGTGAGCGGAATGATGGAAGAGACAATGGCAGAGTATACAGAGGATCGAGGTCGCACGATGAAACGACAAGATCACAAAAACGTGGAAGATCACCGGCTTCCAGCAATAACAATTCACTGAATCAACGCGATAACAATAACAAACGTCCGAATTACGGTGCGTCCAATGGGACGACCGTGACCTCGGGTATACAACACTGCGAGCTGTGCGAAAGAGCTGAATTTGCCACGGAAGCGGAGCTTCAGGCGCACAAAAAATTGGTCCACACGCCCATGAAGCTTCAAGCCAAGTCGTTGCCCCTGCTGAGCATGACATGCGCATACTGCGGCGAGGTTTGCCGCTCGCGAAGTGATCTCGAGTCGCACACGAGGATTCAGCATGCTTCGAGCGAGCCCGGGGGACGCCACAAGTGCAATATTTGCGACGAGGTATGTCCCTCGGGTGGCATATTGGCCGAGCACAAGCTTCAGACGCATTGCAAAATTCAGCTCAGCGACACCTGCATCGTGTGCCGCGGCTCATTGGCGAACGATGATCAGTTCATCGAGCATGTGCAACGACACAGCCTGGAGATCAGTGAAACGCAGCAGCGATTGGACAGCTCGCTGCCCCTTTTACCGGCAGCCTGCGTCGTTTGCCGACAAACACTCATCAGCGATTTGGAGTGTCGTCTTCACGCGGCGTATCACTTGAGGGGCTCGAAAGCTCCTCAAATTTCTAGCTCCAGTCCAATTCCGAATCAGAACAAAACAACTCAGCAGCAACGGTCATTCCGTCAGACGTCCCTGAGCTGCTGTCTCTGCTTGCGTGAATTCAGCGCCGATGACTTTGTCAGCTTACCGTCTAATCACGTTGGTAGCGGTTTATCGCCTCTGAGAGTCTGCAAACCGTGTTACGTCAGGCACTCGCAAGGCTTGCCGATACTCAGTTCGCCCTACGAGCACGTTAGACAGTCCAAAGTCGAAAGAGTCAGCTGGATCAGCGACAAGGAATCGAGCAACAGGGAAGTTTCGGGAGATCAGCGGAACGGTGACGGATGTCACAGCGCTGAAGAGCCCAATGGGAATCCGAGGATCGCGATCGAGACAGGTTCGAGCGAGACGGATGACATGAGGTGCAACGAGTGCGGTGTCAAGTTTGAAACTTCTGACGAGGCTGAGATTCACAGAATCAAGGAGCACGGAACGAGCAGAGGAAACGCAAACACCTATACCTGCATACAGTGCCAGATGTCTTTTCCAACTGAGGATAAAATTCGACAACACGTGAGGAAGATGCACCTGGAATCGACGAGAAAAGCCTCGATTGAGGCGCTGCGCTGTCATCTTTGCGTATTCGAAGCGAACAGTCCTCTGCAACTCCAGGGACACCTGATTGAACATACTTTCGCCGGTTGCGCGGGACTCACATGTTACCTTTGCCAGGGCCTGTTCACGACTCCTCTTGCTCTTCAGAATCATATGCTACAGCAGCATGGACTCGGTGCCCGTCCCTATGACTGCAGTTACTGCAGcctaaaatttttctttcgcatcGAATTGGATCATCACGTGTCGATGGTGCATCGCAGAAACGATGCATCATCGCCCAATGTTGACGCTGACCAAGAGTCGGCCGCGGATCATCGAAAAACGTCGTTGGAAGATCCGAGTACGATACGGGCGAGCGATGAGGTGCATGCTGGTAATTCACGTGCAAAGATTGTCACGGTTAAGGAGGAAATTGTTAATAGTCCCGAGGCGAAAGAATTGGAGGAAAATTTTGGGCAAAATGATGACGCAGAACCGAGACCAGAGGAACACGCGGTAGAAACGAAAATTGAATCATTTGGGATAACGAACGACGGTGACAAGATACAATCTTGA
Protein Sequence
MLFKGNSSRLELLIGKIQAHKESPSPPRGDKCTPRSKDALGTGSSSWHSEDGGTNSRRGGETPSSCATPTSASFPSEPEVDAEIGINADGNNPAAPYPCQFCDRTFPRLSYLKKHEQSHGDQMPYRCSWCSRLFKHKRSRDRHVKLHTGDRRYRCSHCEAAFSRSDHLKIHMKTHDNQKPYQCTACSRGYNTAAALTSHMQSHKKHPNSNQNPKLDVDYGRRSVSSHSTSSPPIQNSPSPSLNLSLNLKNSLKSQPSIHNNGNGGPKTPVLNSPLKLACMYCTKDSFTSMQQLQLHVHAMHQAILNGESLSMESSGQAKPEASDTKCRDQQPTMEGSVSNEYDRTCRHEGREKFTEADRGSSLDNGFSCGQCTMRFSNLSELRDHLLTIHRNDGFGTALMMCPLCGIPCASAASYAEHYVLQHCDNHRLTTKDSRHRDWDLTKTNGSRESSRPGSEDHAVTSRNDHGTSEAADLTKKHSRPGDTGYTSGTLLCGQCGAALRDFESFREHLARHLQADQQSGEVLPRNPCPKCGTNFPEREDMLAHLTKHYLGQVTKEYTCGACKKCYHHPDLLQRHLLDAHAHHLYRCAVCRDTFDSRVAIQVHFAVKHSQECQVYRCSVCSSSSNESSPDTSPVDGKNCFRSEAEMANHVRTIHAPRTVIGASPTRKSPAPTTVTTMTTSSRCVFCGICCNTDLELQLHLASHSTSLYRCPICREGYPVEFLLERHMAQAHHRNGERNDGRDNGRVYRGSRSHDETTRSQKRGRSPASSNNNSLNQRDNNNKRPNYGASNGTTVTSGIQHCELCERAEFATEAELQAHKKLVHTPMKLQAKSLPLLSMTCAYCGEVCRSRSDLESHTRIQHASSEPGGRHKCNICDEVCPSGGILAEHKLQTHCKIQLSDTCIVCRGSLANDDQFIEHVQRHSLEISETQQRLDSSLPLLPAACVVCRQTLISDLECRLHAAYHLRGSKAPQISSSSPIPNQNKTTQQQRSFRQTSLSCCLCLREFSADDFVSLPSNHVGSGLSPLRVCKPCYVRHSQGLPILSSPYEHVRQSKVERVSWISDKESSNREVSGDQRNGDGCHSAEEPNGNPRIAIETGSSETDDMRCNECGVKFETSDEAEIHRIKEHGTSRGNANTYTCIQCQMSFPTEDKIRQHVRKMHLESTRKASIEALRCHLCVFEANSPLQLQGHLIEHTFAGCAGLTCYLCQGLFTTPLALQNHMLQQHGLGARPYDCSYCSLKFFFRIELDHHVSMVHRRNDASSPNVDADQESAADHRKTSLEDPSTIRASDEVHAGNSRAKIVTVKEEIVNSPEAKELEENFGQNDDAEPRPEEHAVETKIESFGITNDGDKIQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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