Rexs007644.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Rhorus exstirpatorius
Gene Symbol
topi
Assembly
GCA_963564615.1
Location
OY751315.1:24458362-24461964[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.43 43 5.2 0.8 1 23 261 283 261 283 0.85
2 16 8.6 8.5e+02 1.2 6.8 2 23 290 312 289 312 0.89
3 16 0.003 0.3 12.0 0.2 2 21 319 338 318 339 0.92
4 16 5.3e-05 0.0053 17.5 0.8 1 23 346 368 346 368 0.97
5 16 1.8e-07 1.8e-05 25.3 1.2 1 23 374 396 374 396 0.97
6 16 0.017 1.7 9.6 1.4 2 23 408 430 407 430 0.90
7 16 0.032 3.2 8.8 5.6 1 23 446 468 446 468 0.97
8 16 0.0049 0.49 11.4 0.5 1 23 474 496 474 496 0.95
9 16 0.0072 0.72 10.8 0.8 1 23 506 530 506 530 0.93
10 16 0.037 3.7 8.6 0.0 1 19 545 563 545 566 0.80
11 16 0.0086 0.85 10.6 0.3 1 23 571 593 571 593 0.98
12 16 2.3e-06 0.00023 21.8 3.1 1 23 599 621 599 621 0.98
13 16 0.00021 0.02 15.7 0.6 1 23 627 650 627 650 0.97
14 16 0.056 5.6 8.0 0.7 1 23 656 678 656 678 0.89
15 16 3.7e-07 3.7e-05 24.3 2.2 1 23 684 706 684 706 0.99
16 16 4e-06 0.0004 21.1 5.0 1 23 712 735 712 735 0.96

Sequence Information

Coding Sequence
ATGACGAGTACGATCATAGCCGATTCGATCAGCACGACATTTAGCGACCGAGAGGATTACATTGATGACGTCGATGAAGTGGCAAGTATCGTCTGGTCGCAGGATGATTCAATTTCACCGGGTGATGTCATCGGGAACGATACGAAATCGGGATCGAATGTTGACGATGAGAGTCCGGGACTTTGCCGATTGTGCGCCGGTCAAGCCGTCAATCCCGTTTACATTTACTCGGAATTTGGCGAATCGATGAAGCTCGCGCACAAAATTAATACGTGCCTGAGCGTTAAGATAAGAAAAACGGATTCTCTGCCGAAGCAATTGTGTCACATATGCGCGGAGAAGATAAATTGGTGCGACACGTTCGACGTGGAGTGCATAAGAGCCGAGGAGACACTGGAAACGATGCTGCGCGACGAGAGAAAACGATTGGAAAATATGAAGACCGCATCAACGACGAGCACGGAATGCGACATGGAAAATTGTCCATTGTGCGTGAACGGTAATATGCGAGCTTTGCGACCGAATGATGATAAGACGAGCTTCGTGGAAACGTCGTTGCGCGACGATGATATAGTCATGGAGAGCAGCGACGAGGAAGCTGAATTGTTAAATCATGATACTGAAAAGGGCGCGAATCGCGACGATTCGACGAGAACGGATTGTCAAGCGAACAATAGCCAGAAATATTTGAAATGCGGCGCATGCACGAATCTTTATCGCACGAAGGATTGCCTCGATGCTCACAAATGCAAGCCGAATATTCAGCTCACAGCGAGACCTTACAAGTGCCAGTTATGCGATATGATATTTCCGTTCGAGGAACGCTTGAATTTTCATGCGAAATATCACAATGGCGCCAGGGAGCTCTACTGCCCGATATGCAATATCACGTTTTGCAAGGAAATCAAGCATTTTCATCATTACAAGCGTTATCATTGCGAGGAAAAGGGCGTATCGTGCCTTCAATGCGGCAAATTATTCCCTAATCAGCAAGAATTGCGCGTTCACGTTTGCGTCGATGGAAAAACCCGTCCGCACGTTTGTGAAATTTGCAGCAAAGGTTTCACCGATGGTTATACGCTTAAGCGTCACGTTGTCACGCATCTGCCGGAAAAACCATACAAGTGTCCGAGATGCGACAAAAGTTTTACCCAAAAGTCACGATTGAACAAGCACATAGCAGGTCACGATGTCGTTATTGACAATAGCCAGATAGCATGGAAATGCCACGATTGCGGTGAAATATTTGACAATTGCAACGAGGCTGATCGTCACGGACGCGATAATCACGAGTCAAGGATAAGCCTGATCGAGGAATTAACGACATCGAAGATATATCATTGCGAATTTTGCAACGGTTGCTTCAACGATCTGTCGTTTCTTCGCGAACATCGGAAGCTTCACGTTATCGAGAAGCCATACACGTGCAGGAATTGCGATAAAACTTACAAATCTTATGCCGAGGCGGTGCTTCACTGGAAGGAGCATCCGCGAAATTTTCGCGTCGCAATCGCGTATCCCTGCGACGTATGCGGCAAGGACATGAAGGAATTGTCATTGCTTTACAAGCATCGACGAAAAAGACGCCACTCAACGGCGCGCGGTTCCGAGCTCCTCGCCAATAGCGTCAAATACGTTTGCGAATTGTGCGGCGAGTCATTCGACGATCGGGCCGTTATGGATGAACACGGAAGGATACAATGCTCGAAATTTCCGTGCGACATATGCGGCAATCTTTTGCCAACCGCGAATTCATTGCACGCACACAAACGACGACACAGCGGCCTGAGACCTTACGTATGCAATATTTGCGGCAAAAGTTATACCCAATCGAGTCACATGTGGACACACAAGAGATTTCACATGGGCGTCAAGCCTTACGCGTGCCAATATTGCGATCAGAGATTCACGATAAAGCCCGATCTTGCCGATCATACGAGGAAAAAGCATACGCGCGAACGTCCGTTCAAGTGCGACGTTTGCAACAAAGCTTTTTTAACGGGTTCGGTGTTTTATCAGCATCGATTGATTCATCGTGGCGATCGACGCTACAAGTGCCATTATTGCGAGAAAGCATTCACGAGAACCGAGGCACTGAATAATCATATAAAGATACACACGGGCGAGAAGCCCCACGCTTGCGATATTTGCGGCAGATGCTTCAGGCAAAAGGGCGACATGAGAAAGCATCGACGCACCCAGCATATCGTTCTTAAACGTGAATTATTGCCATGA
Protein Sequence
MTSTIIADSISTTFSDREDYIDDVDEVASIVWSQDDSISPGDVIGNDTKSGSNVDDESPGLCRLCAGQAVNPVYIYSEFGESMKLAHKINTCLSVKIRKTDSLPKQLCHICAEKINWCDTFDVECIRAEETLETMLRDERKRLENMKTASTTSTECDMENCPLCVNGNMRALRPNDDKTSFVETSLRDDDIVMESSDEEAELLNHDTEKGANRDDSTRTDCQANNSQKYLKCGACTNLYRTKDCLDAHKCKPNIQLTARPYKCQLCDMIFPFEERLNFHAKYHNGARELYCPICNITFCKEIKHFHHYKRYHCEEKGVSCLQCGKLFPNQQELRVHVCVDGKTRPHVCEICSKGFTDGYTLKRHVVTHLPEKPYKCPRCDKSFTQKSRLNKHIAGHDVVIDNSQIAWKCHDCGEIFDNCNEADRHGRDNHESRISLIEELTTSKIYHCEFCNGCFNDLSFLREHRKLHVIEKPYTCRNCDKTYKSYAEAVLHWKEHPRNFRVAIAYPCDVCGKDMKELSLLYKHRRKRRHSTARGSELLANSVKYVCELCGESFDDRAVMDEHGRIQCSKFPCDICGNLLPTANSLHAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACQYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDICGRCFRQKGDMRKHRRTQHIVLKRELLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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