Basic Information

Gene Symbol
-
Assembly
GCA_003676215.3
Location
NC:84957041-84959625[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 3.8e-05 0.0027 17.5 4.0 1 23 128 150 128 150 0.95
2 18 0.0089 0.63 10.0 0.1 1 23 156 178 156 178 0.97
3 18 0.0096 0.69 9.9 0.4 1 20 302 321 302 322 0.95
4 18 5.2 3.7e+02 1.3 1.6 1 16 355 370 355 372 0.83
5 18 0.36 26 5.0 4.9 1 23 386 408 386 408 0.98
6 18 0.0089 0.64 10.0 2.7 1 23 414 436 414 436 0.97
7 18 0.0046 0.33 10.9 2.3 1 23 442 464 442 464 0.98
8 18 1.4e-05 0.00098 18.9 2.2 1 23 469 491 469 491 0.97
9 18 0.0013 0.093 12.7 4.9 1 23 497 519 497 519 0.94
10 18 0.032 2.3 8.3 3.7 1 19 525 543 525 546 0.86
11 18 0.00099 0.071 13.0 2.0 1 23 553 575 553 576 0.96
12 18 0.00016 0.012 15.5 3.5 1 23 581 603 581 603 0.98
13 18 3.8e-05 0.0027 17.5 5.1 1 23 609 631 609 631 0.97
14 18 5.5e-06 0.00039 20.1 4.3 1 23 637 659 637 659 0.98
15 18 5.2e-07 3.7e-05 23.4 0.6 1 23 687 709 687 709 0.98
16 18 8.9e-05 0.0063 16.3 0.2 1 23 717 739 717 739 0.91
17 18 0.3 22 5.2 0.0 5 17 748 760 747 761 0.90
18 18 0.0007 0.05 13.5 0.4 1 23 772 795 772 795 0.94

Sequence Information

Coding Sequence
atggaGAAACgtacacaaataaatttagagAAATTTGATagtttaatacctataaataaaaatatttctgttgAAGCCGAAAACaatcaacaattaataaataatgatatttacattaaaaaagagCCAGAAAACAACACtaattattgTACTTCTGATGAAGAAACAGAACATGTTAACCAGTGCACaagtacaattaaaattgaaagagATGAACTTAACGGTTATATGTTTGAAAGTATAATAGAAGTAATTGACACCcaattaacagaaaaaaatgttcatggtGCTAATCCAATAGTAAATGTTAATGATGATCGTTCTACTATTGTTAATGATTGTTCAACTGTTAGTGAACAGTTACACAATGAAAAGAATCAATACCagtgtaatatatgtaataagcaATTTCATGACAAATATAACTTAGAAGTTCACAAATCATTTCATGCAAATATCAAGAAATTTGAATGTACTGCTTGTGGTGTgcaatttttggatttatcTGATCTTAAAAGTCATTTGATATCTCATATAGACCATGATATACAATTGattgaaaatcaatttgtCCAACAAGAatgtaatagtaatttatgtaataatattaccacaCTTGAAGGAATAAAGAAAAGTTGTCACGACAGTGGAGTTCCTattcaaaatgaaataattatcaaaattacattGGGGTGTTCAGTTGTTCAAATTGAACAACCAAACATTGAAAATTCTTTATTAACTGAAGTTAATAGTATTGATTCAAGAAATAGTGTTGATTcagatttaaatgttataaatgcaGTTAATTCTGTTGCTCTAGTACATCATGAATCTGTTAATGTAGCTGAATCATTTAATGCAAGTTCAGGTAATTCAAAAgaacataaaaatgataaagttTATGAATGCTCAAAATGCAgtagattattttatgatcgttcaagtattataaatcatcTCAACCCTGATAAATATCATTGTACCAACTGTTGTAAGTACATTGATATTTTGTCTTCTTTGAAATATCCTGTTAGCTTTAAACCAGGATCACCagtatattttgaatgtaatGAATGTTACAATGAGTTTTATACACTCAAGAgctttagtaaatataaaagtgcacaaagtaaaaaaaataatgacaggCCATACGAGTGTGGTGTTTGTCTAAAAAcacatataaattgttatcacTTTGCTGCTCATCAACGGTTACATAAAGGTGAGAGACCATACCGGTGTTATGTTTGTAATAAACTTTTTCATGCCAGGTTTAATTTAGAAGCTCACTTGTTTTCGCACCAAAACATCAAAAGATTTGAGTGCTCTTTGTGCTCAAAAATGTTCCTTAAATTAAAGTATCTCAAAATTCATACAAGATCACATTATTCTTTCAAACATAAATGCAACATATGTGGTAAAGAATTTGAATCATTGAATTCTTTGCAAATGCATCAGAATttccattttaaatacaaaccacatacatgtattaaatgtggcaaatcattttcaaaacttcAATCTTTTACACAACATTTGAAAAGGCACagtgatttaaaaacattcaaatgtGTTATGTGTGATAAAAGTTTTAGaacttattttgattttatatgtcATAAAAGAGAATCTAATGGAGAAAAGCCTTACAAGTGTGATATTTGTGAAGATGAATTTACTCAATTAATCGATTGGAAAAAACACAGAAAAACACATCatggtaataaaatgtttgaatgcGACAAATGCCATAAAAAGTTTGTCAGTAAACTTAGTATAAgagtacatttaaaaacacacaaaGAATGGAAAGAACATACATGTaaagtatgtaataaaaaatttgcaaataaacataatttatatgtacatgaaaaaattcataaagattttaaacaatatgtttGTAACATATGTAAAAAGAGTTTTATTTCTCATCGTAATTTTACTCGTCATTTAAATCAACACACAGGTGTCAAGCCAAACCAGTGTAATTGCGAGAAAACATATTCATCAGTTCAATCTCTAAATAGATgcaaaaaagataattatacatgtgatatttgtaataaatcttATAGTAACCCTGAAGAACTCAAGGTTCACAAGACTACACATGAAGAATCTACGTGGAAGAAATATGTATGCCAATTATGTGACAAAGCATTTAGCAAACCTGTATTATTGAGAAATCATGATTTAACTCATCTGAATGATAAATCACACATGAACATTTGCCCAAAGTCTTTTATAACTCAAACAGCTCTAAAACTTCTTAAAAGACAGCATACTGGTGAAAAACCATACAATTGCAAATCATGTACTAAGTCATACCCACAAATTAGTTCATTAGTTCGACACGAAGCTAGagtacacaaataa
Protein Sequence
MEKRTQINLEKFDSLIPINKNISVEAENNQQLINNDIYIKKEPENNTNYCTSDEETEHVNQCTSTIKIERDELNGYMFESIIEVIDTQLTEKNVHGANPIVNVNDDRSTIVNDCSTVSEQLHNEKNQYQCNICNKQFHDKYNLEVHKSFHANIKKFECTACGVQFLDLSDLKSHLISHIDHDIQLIENQFVQQECNSNLCNNITTLEGIKKSCHDSGVPIQNEIIIKITLGCSVVQIEQPNIENSLLTEVNSIDSRNSVDSDLNVINAVNSVALVHHESVNVAESFNASSGNSKEHKNDKVYECSKCSRLFYDRSSIINHLNPDKYHCTNCCKYIDILSSLKYPVSFKPGSPVYFECNECYNEFYTLKSFSKYKSAQSKKNNDRPYECGVCLKTHINCYHFAAHQRLHKGERPYRCYVCNKLFHARFNLEAHLFSHQNIKRFECSLCSKMFLKLKYLKIHTRSHYSFKHKCNICGKEFESLNSLQMHQNFHFKYKPHTCIKCGKSFSKLQSFTQHLKRHSDLKTFKCVMCDKSFRTYFDFICHKRESNGEKPYKCDICEDEFTQLIDWKKHRKTHHGNKMFECDKCHKKFVSKLSIRVHLKTHKEWKEHTCKVCNKKFANKHNLYVHEKIHKDFKQYVCNICKKSFISHRNFTRHLNQHTGVKPNQCNCEKTYSSVQSLNRCKKDNYTCDICNKSYSNPEELKVHKTTHEESTWKKYVCQLCDKAFSKPVLLRNHDLTHLNDKSHMNICPKSFITQTALKLLKRQHTGEKPYNCKSCTKSYPQISSLVRHEARVHK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-