Basic Information

Insect: Rhodnius prolixus
Gene Symbol: ZFHX3_2
Assembly: None
Location: HiC:64340452-64346998[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00027 0.03 14.9 1.8 3 23 46 67 45 67 0.94

2 15 0.00029 0.033 14.8 0.2 1 23 112 135 112 135 0.96

3 15 0.0027 0.3 11.8 2.8 2 22 190 210 190 213 0.90

4 15 0.57 63 4.5 1.1 3 23 227 250 225 250 0.88

5 15 0.0064 0.72 10.6 1.7 1 23 269 291 269 291 0.97

6 15 0.0031 0.35 11.6 0.7 2 23 298 320 297 320 0.96

7 15 0.00037 0.041 14.5 3.9 1 23 423 447 423 447 0.92

8 15 0.0044 0.49 11.1 0.6 1 22 467 488 467 491 0.89

9 15 0.00059 0.066 13.9 0.2 1 23 547 571 547 571 0.93

10 15 0.012 1.4 9.7 0.2 2 21 679 698 678 699 0.94

11 15 0.13 15 6.5 2.0 2 19 844 861 843 866 0.91

12 15 9.4e-05 0.011 16.4 2.5 1 23 1448 1470 1448 1470 0.99

13 15 0.00046 0.052 14.2 0.8 1 23 1559 1581 1559 1581 0.98

14 15 0.0051 0.57 10.9 0.4 2 23 1771 1793 1770 1793 0.96

15 15 0.47 52 4.7 4.1 2 23 2028 2051 2028 2051 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00027	0.03	14.9	1.8	3	23	46	67	45	67	0.94
2	15	0.00029	0.033	14.8	0.2	1	23	112	135	112	135	0.96
3	15	0.0027	0.3	11.8	2.8	2	22	190	210	190	213	0.90
4	15	0.57	63	4.5	1.1	3	23	227	250	225	250	0.88
5	15	0.0064	0.72	10.6	1.7	1	23	269	291	269	291	0.97
6	15	0.0031	0.35	11.6	0.7	2	23	298	320	297	320	0.96
7	15	0.00037	0.041	14.5	3.9	1	23	423	447	423	447	0.92
8	15	0.0044	0.49	11.1	0.6	1	22	467	488	467	491	0.89
9	15	0.00059	0.066	13.9	0.2	1	23	547	571	547	571	0.93
10	15	0.012	1.4	9.7	0.2	2	21	679	698	678	699	0.94
11	15	0.13	15	6.5	2.0	2	19	844	861	843	866	0.91
12	15	9.4e-05	0.011	16.4	2.5	1	23	1448	1470	1448	1470	0.99
13	15	0.00046	0.052	14.2	0.8	1	23	1559	1581	1559	1581	0.98
14	15	0.0051	0.57	10.9	0.4	2	23	1771	1793	1770	1793	0.96
15	15	0.47	52	4.7	4.1	2	23	2028	2051	2028	2051	0.89

Sequence Information

Coding Sequence: ATGAAAGATGGACAATCAGACATGAGAAGTGATCAAGCTACACAACTGCACCACCATCAGCAGCAAATAACTGAACAACTTTTACAACATCAACGAGAACAGTTAGCAGCAGCTGCCCAACAAGAAGAACGAAACTGTCCATATTGTAATTTTTCCTGCAGTACAGAATCTCAACTACAACAGCACATAATCAATCAACACCAACAACCATCACATCAATCTCAAACGATACATCAGCAACATCAACAACAGCAGACTACGTCAACGCATCAACAGCAGCATcaccagcagcagcagcagcagcagcaacaacagcagcagcagcaaaAAGATTTCCAATGTCCATTATGTCAAGATAGTTTTAAAGACAAAGGTTCTCTAGAAAATCACGTGATGCAGATACATTCGGTGAATTCAGAAGGTTTGCAAAGGCTTTTACTGTTAGTGGATCAGTCGCATTGGTTGAATCAGCCACAAACGAGAAATCAGTCTACATCCAGCTCCTTTTCagacagagaaagagaaaaagatgaAGAGagagaagaacaagaagaagctGAAGATGAACGATGTCAGACATGTAatagaacttttaagaatatcGATGAATTGTGTACTCATCAGAATGAGTCTGGCCACTTAGAACTGAAACAAACACCTAGTGGTCCTGGTTATCTATGCTGGAAGAAAGGTTGCAATCAATATTTTCAGAGTGCACATGCTTTGCAAATGCATTTCAGAGAAATCCATGCTAGAGGAGGCGCTGGACAGAACATGGCCGTGTCTGAGAAACATGTTTATAAGTATAGATGCAATCAGTGCAGTCTGGCTTTCAAGACGATGGAAAAATTGCAGCTTCATTCACAGTACCATCTCATTAGAGATGCTACTAAGTGTGTTCTTTGTGGAAGAAGTTTTAGATCTATACTGGCGTTGCATAAACACGTGGAAACGGCCCATACAGATCTGTCAGAGGAAGAGGTTGCCGCCTATAAACAAAGTTTGATGAACAACCCACTTCTACTGGCTGGCATAAGTGGCCAGATTCTAGATCCTTCCACAAATGAATTATTGAAACGAGAGAGTATGAAAATGGACACTGAAGATATAGAATCGGATGATGTCAAGGAACAGGATGAGTCGAGCCACCAACCAGAAGGCGATAACAGCGATGATTCTATAGTATACAAAGATCAACAATTTCTAGAGGATTACCTCAATAGTCAAGCTATCGCCGAAGATTCGTACAATGATCCTGCAAGGAAGTATAAATGTCATAGGTGTAAGGTGGCATTTACCAGACAGTCATACTTGACCAGTCACAACAAGACACTGTTGCATAGAAAAGGTGAAAAACTTTCTTATCCGATGGAGAAATATTTGGATCCGAACCGGCCGTACAAGTGCGACGTTTGTAAGGAATCATTTACACAAAAGAACATCCTCCTGGTGCATTACAATTCGGTGAGTCATTTGCATAAATTAAAGAGAGCAATGCAAGAACAACAGCAACTGCAACagaataacaacaacaacaatgcAGTTTCACCTCAGGTAGCCGCTGCGGCTGCGCTGGCCGTCCAACTGGGAGTGCCGCCGCCGATGAAGGTGGCCCAAGAAGAGGACGACAAGAAGCCGTACAAATGTAATATATGCAAAGTGGCTTATAGTCAAGGTTCAACGTTGGATATCCATATGAGATCAGTTCTGCATCAGACAAGGGCCTCCAAATTGCAAGATCTTGCTATAACCGGGCAAATAGATTTAAGCAAACCTTTAATCGAACAGCCAGAACCGCAAAAAGCTCAGGACCAGCATAAAAAGTTGATTCAAGACATGCTTGGTTCTTCACCAAAACAACTTCTCTCATCACCGCCTTCCGGAGGTAGTTCTGGATTATCTGGTTCATCGCCGAGTTCGTCTGGACCGCCGCCAGCCGCATCTACGCCAAACTCGGCACCCTCAGTTCCTACTAGTATAAATAACTCAACATCGAACTCTGTGATAGCTTCGTCCCCGAATTCAAGCATGCTTACCTGCAGCCGATGTAATGCGTTGTTCGCTAACCAGGACCAACTCAACACGCATCAACAGTTGTACTGCATGTTCAACAATCCTATGTCCATGTTTCCGCCGCTCCCTACTCCTCCATCTTCTTCCGCTAATCTCTCATCACCCCAGCCGAACAGCAAAACTCCTCCTCCGGTACCGCTTACACCTATGGCAACTCCATCGAACGCCACGGATGAAGCATTTCCTAGAATATCTCTTCCTACTAAGAAATCATCTCAGATGTATAAACATCTGTTGGAAAGCTTTGGCTTTGATCTTGTGATGCAGTTTAATGAAAACCATCAGCGCAGACAAAggaaagagagagaagaaaCGGAAAAGCTTCTATCCGAAATCTCTTCGACAACTCAACCCGTTGAAGAGGCTACAAACACTCCACTTATAGAAGAGCAGGAGAAGGTAGAAgtaaaagaagaggaagaacAGCTGGACGACCTTCCTGAAGTTGCTAAGTCTACTTGTCAACATTGCAATAAAGAATTTTCTAGTGTTTGGGTATTAAAAGCTCATTGCGAAGAAGTTCACAGAGATCTAGTACCTTTGGACTTCCTAGAGAAATATGCCCAACAAATAAAATGTGAGTACGAGAAGAAAGGTGTTCCTGCTCCCACGGTGACGTCAACTACAAATCAAGAAACTTCAACGTCAACCGCCACCACTACTACACCGGAAAAAGATGAAGACAACAAAGAAGCAATCCAAGCTAAAATTGGTATACAGGCACAACAAACTCCTGAAAATGTGACCGCTCCTTCCACTCCAACAGCATCGTCGACACCAGCTTCATCCACAGACTCGCTTCCGGCAACACTTAGCAATTCTCTAGCGGCCGCAGTCGCAGGTATGAGCGGAAACGCGGCAAATATGAACGCCGCTCTTGCTCAGCATATGAACGAAATGCAAGCGGCCCTAAATGTAATGGCCGCCTCGCAATTGCAACAGCAGTTTCAGCAATTCAACCCTATGATGATGGGAATGGCTGGATTAGGCATGGGTCTGCCCTTAGGATTGAACATGCCAGCTCTTGCTGCAATGAATCTACAACCTCCGCTTGTGCCTATGATGATGCCTCCTCCGAATTTCGACTCCATGGTGAATCTTGGGCAAAATCAACCGAACATATTCAATCCTCAAGCAGTGGACGCAGCTGCAATGATTGCCAAACAGCAAGCCATCATGCAGCAACAGCAGCAACAAGCGGCAAGTGCATCTCAACAGAAACGTGCTCGAACTCGCATTACGGACGATCAGTTGAAGATTCTCAGAGCTCACTTTGACATAAATAACTCCCCTTCAGAGGAACAGATCAATGACATGGCAGCACAAAGCGGCTTGCCACCAAAAGTAATTAAACATTGGTTTAGAAATACACTCTTCAAGGAACGTCAAAGAAATAAGGATTCTccttacaattttaataatcctCCATCAACTACCCTCAACTTGGAAGAGTATGAAAAAACTGGTGAGGCTAAGGTGACGCCGTTGACCCCTGAGGAACAGCAGCAAGCGTTAACTCCTCAAGCCAAAGAACCGGCGAAAACTGCTCAACCAGCGAATAGTAAACCTTCGCCGTCACCTGTTCCTCCATCTCCTCAACCGCCGCCTTTTCATCAGCAGCAGGGGTTTCCGCACCCCGATATGATAAAAACGGAACCAAGAGAGCAGGATCCTGAACCGCAGGATGAGAAGCCTCAGTTCAATCACAATCCAATGCAATCACCCGTCAGTCCTAATGAAAGGATGAACATAATTACGTCACGTAATAATTCCCCAGAGAATCTTACactaacatcaattatctcttCTCAGTTGGGCTCTAACGTCACTAGCATGCAACAATCAACAATGACGTCACCTCACCCAAACATGCTACCACCGCCGAAACTAACACCACCAAACTTCCCCCCGCCAAATCACCAACAAATAAATTTGCCAAATTCACAAGACTGTTTCACGCACGCAATGATGGGCAATAATGGCGGAGGTTCCGGCGGTTCTACTGGGAAGCGAGCCAATAGAACACGGTTCACTGATTATCAGATAAAAGTATTGCaggagttttttgaaaataatgcaTATCCAAAGGATGATGATCTCGAATATCTATCGAAACTATTAAGTCTAAGTCCTCGAGTTATAGTTGTGTGGTTTCAAAACGCTCGCCAAAAAGCAAGAAAAGTTTACGAAAATCAACCTCCGGTGGAATTATCGCCTGGAGTTGATGAAACTGGTGCTGGAAGATTCCAAAGGACGCCgggtttaaattatcaatgtaaaaaatgtttgctggTATTTCAGAGATATTATGAACTGATAAGGCACCAGAAGACCCATTGTTTCAAAGAAGAAGACGCCAAGAGATCGGCTCAGGCTCAAGCGGCTGCGGCGCAAATAGCTGCAGTACTATCTTCTGAAGATTCCAACTCCTCGACAATAATTGAACAAAGCGCACAACACAGTCTTGCTGCATTGTCTAACAGCAGCAATCCGTCTACACCAGCCGCTCCAGTCACCCCAACACCTTCTTCCCAGAATATGTTCCCTCCATCGCCAGTTCCTAACACTACAACGACGCCAACACCCGATGGAAAGGATAATTTTCAGTGTGATCATTGCAATTTAGTTTTTCCAAGATTTGAACTTTGGCGAGAGCATCAGCTAGTACATATTATGAATCCAAATCTTTTCCCAACATATCCTCCTGACAGTCCTTTTGGAATTCTCCAGCAACACGCCCAAatgcagcagcagcagcaacaacaacaacaacagcagcaacaacaacaacagcagcagcaacaaTCACAAAACCAACAACAACAGACGCAATGTCAGCAGCAACAACAGCAGTCCCCACAACAGTCACAAagtcaacaacaacaacagacaAGTCAACAACAAAAACTGAGTCTTGATGCGCTAAATCCTAATACCCCACACCCTCTCATTTCAATGCTCGCCTCCAACAAACGTAAATTCGACGAGTTCGAGGAGACCAGTGAAAAAGAGGGCGAACAACCAAAAGATAAGAGGCTAAGGACAACCATTCTACCAGAACAATTGGATTACCTTTATCAAAAGTATCAAATTGAAAGTAACCCTTCAAGGAAGATGCTTGAGAATATTGCTCGTGAGGTTGGTCTTAAGAAGCGAGTGGTGCAAGTTTGGTTCCAGAATACCAGGGCTAGGGAAAGGAAAGGACAGTTTAGGGCTCATTCGCaggtaattaataaaagatgtcCTTTCTGTCCTGCGCTtttcaaagtcaaatctgcccTGGAAAGTCATTTAACAACTAAACATGCAGATCAGTGTTCCAGAGGTGAAATAAACATTGATGCAATTCCCGACGAAGAATCTACCACCGATGCTGCAAGCTTTCAGGATAAGTTTAGCAGTATAATGCCACCAATGTTTTCACAATTCAACGATGTTGAAGGTTCCTTAAAGAAATATTACGAAGAATCTATGAAGAGGTATATGAGTGAAGCATTGCAGAATGGTAAAGAAGCTGCTGATCTGACGATGAAGAAAGAAGGTGAAAGTGGAGATTGTCCTCTTGATCTCAGCAAGCCAGTGGATTTAAGTAGACCTATGAAACTATCCTTGGAGCATATGATGATGGATCAGGGTCCATTGACGGATCTAAGTGAACGAAGTCTTTGCGACGATGATAGCGTATCCGAGTGTACGGACAATATGGAAGATGAGTCTAATCCAACATCTCCAGCCTCGAGTACACAAAGTCAACAGCATCAGCATGCCAAATCAAAGAGGTTTCGCACGCCAATGTCCGCCATACAGGTGAAACTAATGAAAACGCTATTCAGTGACTATAAAACACCAACGATGGCAGAATGTGAGATGCTCGGCAGGGAAATTGGACTACAGAAAAGGGTGATCCAAGTTTGGTTTCAAAATGCTAgagcaaaagaaaagaagtacaaAGCAGCTTTACAAAGTTTAGGCGGTCCAACCACTGAACAGACTGAACGACCACCTGAAGAGTGTAAATTTTGCCAATTTAAATATTCCCATAAATATTCCGTACAGGatcatatttttactaaaaaacatATAGATATGGTTAAGTCCTATTTAGAAAGTTCATTGGTTAAAGACTCTGAAGGGGATTTTACGGTGCCTTCGGCGCCAGGAGCTTCCGGCGAGAGTAATAACAACCACAGCACGCAACAGCAAATGGCCCAGTTGCAGATGCTGCAGCAGATGGCTGGTCTTGCCATTCCCAAGGAGGGCAAAGAACAGCAACAGCCCACTGCAGAGGATATTGCGCTTCTGCAACAGCTCTATGGTGTGGCCAACTATCCACAGGGCTTCATCCATCCGGCGCTACTTTCAGCCACCG
Protein Sequence: MKDGQSDMRSDQATQLHHHQQQITEQLLQHQREQLAAAAQQEERNCPYCNFSCSTESQLQQHIINQHQQPSHQSQTIHQQHQQQQTTSTHQQQHHQQQQQQQQQQQQQQKDFQCPLCQDSFKDKGSLENHVMQIHSVNSEGLQRLLLLVDQSHWLNQPQTRNQSTSSSFSDREREKDEEREEQEEAEDERCQTCNRTFKNIDELCTHQNESGHLELKQTPSGPGYLCWKKGCNQYFQSAHALQMHFREIHARGGAGQNMAVSEKHVYKYRCNQCSLAFKTMEKLQLHSQYHLIRDATKCVLCGRSFRSILALHKHVETAHTDLSEEEVAAYKQSLMNNPLLLAGISGQILDPSTNELLKRESMKMDTEDIESDDVKEQDESSHQPEGDNSDDSIVYKDQQFLEDYLNSQAIAEDSYNDPARKYKCHRCKVAFTRQSYLTSHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQLQQNNNNNNAVSPQVAAAAALAVQLGVPPPMKVAQEEDDKKPYKCNICKVAYSQGSTLDIHMRSVLHQTRASKLQDLAITGQIDLSKPLIEQPEPQKAQDQHKKLIQDMLGSSPKQLLSSPPSGGSSGLSGSSPSSSGPPPAASTPNSAPSVPTSINNSTSNSVIASSPNSSMLTCSRCNALFANQDQLNTHQQLYCMFNNPMSMFPPLPTPPSSSANLSSPQPNSKTPPPVPLTPMATPSNATDEAFPRISLPTKKSSQMYKHLLESFGFDLVMQFNENHQRRQRKEREETEKLLSEISSTTQPVEEATNTPLIEEQEKVEVKEEEEQLDDLPEVAKSTCQHCNKEFSSVWVLKAHCEEVHRDLVPLDFLEKYAQQIKCEYEKKGVPAPTVTSTTNQETSTSTATTTTPEKDEDNKEAIQAKIGIQAQQTPENVTAPSTPTASSTPASSTDSLPATLSNSLAAAVAGMSGNAANMNAALAQHMNEMQAALNVMAASQLQQQFQQFNPMMMGMAGLGMGLPLGLNMPALAAMNLQPPLVPMMMPPPNFDSMVNLGQNQPNIFNPQAVDAAAMIAKQQAIMQQQQQQAASASQQKRARTRITDDQLKILRAHFDINNSPSEEQINDMAAQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLTPEEQQQALTPQAKEPAKTAQPANSKPSPSPVPPSPQPPPFHQQQGFPHPDMIKTEPREQDPEPQDEKPQFNHNPMQSPVSPNERMNIITSRNNSPENLTLTSIISSQLGSNVTSMQQSTMTSPHPNMLPPPKLTPPNFPPPNHQQINLPNSQDCFTHAMMGNNGGGSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPPVELSPGVDETGAGRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTIIEQSAQHSLAALSNSSNPSTPAAPVTPTPSSQNMFPPSPVPNTTTTPTPDGKDNFQCDHCNLVFPRFELWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQMQQQQQQQQQQQQQQQQQQQQSQNQQQQTQCQQQQQQSPQQSQSQQQQQTSQQQKLSLDALNPNTPHPLISMLASNKRKFDEFEETSEKEGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHSQVINKRCPFCPALFKVKSALESHLTTKHADQCSRGEINIDAIPDEESTTDAASFQDKFSSIMPPMFSQFNDVEGSLKKYYEESMKRYMSEALQNGKEAADLTMKKEGESGDCPLDLSKPVDLSRPMKLSLEHMMMDQGPLTDLSERSLCDDDSVSECTDNMEDESNPTSPASSTQSQQHQHAKSKRFRTPMSAIQVKLMKTLFSDYKTPTMAECEMLGREIGLQKRVIQVWFQNARAKEKKYKAALQSLGGPTTEQTERPPEECKFCQFKYSHKYSVQDHIFTKKHIDMVKSYLESSLVKDSEGDFTVPSAPGASGESNNNHSTQQQMAQLQMLQQMAGLAIPKEGKEQQQPTAEDIALLQQLYGVANYPQGFIHPALLSAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01301461;
90% Identity: iTF_01301461;
80% Identity: iTF_01301461;