Rros009470.2
Basic Information
- Insect
- Rhingia rostrata
- Gene Symbol
- zfh1_2
- Assembly
- GCA_949824845.1
- Location
- OX463756.1:18647247-18694200[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.82 1e+02 4.4 0.3 2 23 57 79 56 79 0.90 2 9 0.00012 0.016 16.4 0.1 1 23 276 298 276 298 0.98 3 9 3.5e-05 0.0045 18.1 1.7 2 23 308 329 307 329 0.97 4 9 1.4e-05 0.0017 19.4 6.6 1 23 338 360 338 360 0.99 5 9 0.00029 0.037 15.2 1.2 3 21 368 386 366 387 0.94 6 9 0.00033 0.041 15.0 0.5 2 21 635 654 634 655 0.92 7 9 1.3e-05 0.0016 19.5 0.5 1 23 1005 1027 1005 1027 0.94 8 9 3.8e-05 0.0047 18.0 7.3 1 23 1033 1055 1033 1055 0.98 9 9 0.0024 0.31 12.3 4.3 1 21 1061 1081 1061 1082 0.96
Sequence Information
- Coding Sequence
- ATGCCATCGTCACCAGCGTTCTCCATGCAGTTTCCATCACTGGCATCGAGCTTACACCACCACAGCCAAATTAAAAACGAAGATAGCAGTACAGCATCATCGGCGGCAACAGCCGCCACAACCACCCAACAAGGTGGCGGCGGAGGAGGTGTCGGTGACTTTATAGTCAAATGCCCGCAATGTCCTCAACGATTATCTGGCTTTCAGGCTCTCCATGAACACCTTGTGAATGAGCATTCACATGACAAATTCACCTTCGAGAACCACCACAATGACTACCACATAGATCGTGAAATGGATTACAGCACCGGTCGGCATGATAACAAACAAATgcacaataacaacaacaatttaaacaataacaacaacaataacaataaaaacaacaacaatttaaaaCTCCATAGTATTAGCAACAACAATTGTCATTCGTCCTCCTCCACCGGTTCAACATCACTGATACCAAATGGCAATGGTCAAACATCACCCGTACCCTCATCGCATTCACCTCTGGTGGGAGCAAGTGCCCAACAACGCACCACCCCACCAACCGATCTCAGTTCACAGTATCATCATCATGCGATGGCAATGGCCGCCCTAGCTGTTGGCATGTCCACATCGGCCACAGCCGCATCCAATGGTTATGATGCAAGTAGTGCTGCTGCCATGGCCGCTGCTGAGGCGATGGCAATGGCTGGTAGTCGGTCAACTACGAGTCCATTGAATGGTCATAATGTTGGCAATGGTGGTGGCATGGTGAATGGTAATTGTGGTGCATCAACggcgtcatcatcatcgtctaCGTCATCGATGTCGGCTGGTCCCTACCAATGTTCACAGTGTTCGGCTGCATTCCCAAACCGTGATCTCCTCGAGAAGCATGAACTGATGCATTCACCGAATTCAACAGGCGTTAATCAGAGCTGCAAAATCTGCCATAAAGCATTCGCCAACGTATACCGTCTGCAACGGCATATGATCAGTCACAATGACTCGGAACTGTTGCGTAAATTTAAATGCACCCAATGCGATAAGGCCTTCAAGTTTAAGCACCACCTTAAGGAGCACGTACGCATCCATTCCGGTGAGAAGCCATTCGGTTGTGATAATTGTGGAAAGCGTTTCTCACATTCCGGTTCGTTTTCGAGTCACATGACCTCGAAGAAATGCATCAGTATGGGACTGAAGTTGAACAACAACCGGGCGATGTTGAAGAGCTTAGAAAAGAGCGGAGTGTTGGGTGGTAGTCCAAATGGTAAGCGATCTGGACAACCTCCAGCTGGAGCGAATCCATTGAACTACTTCCCACATGGTTTGGGCGGCGGCGGGCCCGATGGACCAACGAATCCACCGAACGGTAGTAATTTCTATCAGATGCTGCCAAAGTACAGTGACTATGGTGCGATGAATGCTGCACTCCTGGCCAcattccaaaatccattttataaCATGGCTGCGTTGAATCCAAACATCCATCCGTACAGCATACATCGGTTGTTGGAGTTGACGGCAGCCGGTAATCAGAGATTGCAATCGGATCCGGAAGATCTCATCGAAGAGGTAACTGAAGATGTAGCCGATGAGCCAAAACTTGTAATGGATCTTAAGGACGATTGTGAGAAGGATGCCGATGTCGAGGATGATCATGCCCGTACTTACAGCCGCAGTGACGATGAGGATGATGGCGATAGTCGCAATAGTAATAGTAGCACACCACAAAAGCCAAACTATGACGATTTTAGTGCTCAAGATATGGAAATCCCCCGAATTCGGAGTCCAAGTCCTGTACCAGAGGAAGAGCGACCACAATCGCCCGAGATCAAAGTGgaggaagaagatgaagaaaagAATACTTCACACGAAGAAGTTGAACCAGAGGACGATACCCCGTTGAGTGATTTGCGCTGCAGTCGTTGCGATAAGTCATTCAACCACCCCACAGAGTTGGTTCAGCACGAAAAGGTCCTATGCGGACTAATCAAGCATGAActccagcaacaacaacaacaacagcaccaTCAGCAACTACAACATCACTTCCAATCGAATGAATCCGATAACGGAAACTCCTCATACCTACACTCTGGCAGTGAGGAAGAGCTTGAAGATCGTGAATCGAAAAACGGCAGTGAAGCAGGCGAAAGAAAAGTGCGCGTGCGCACAGCAATCACCGAGGAACAACAAACCGTACTGAAACAACACTATGCCGTCAATGCGCGACCAAGTCGGGATGAATTCCGTGTGATTGCAAATCGACTCTCACTCGACGCTCGAGTTGTGCAGGTATGGTTCCAAAATAACCGCTCCCGAGAGCGAAAAATGAATAACAGCTTCAGCAAAGGTTACCCATCAATGATTCCGGAGCCTCAACAACCCGTAAGCCCACCGCCACCAGCTTTTGAGTCGGTGAAAGAAGATCAACCACTCGATTTATCCATTAAGAAAGAGAAAGCAAGCAACCAGCAGGCGGCACATTCTCCACTCTATGGCAGTGTTCCCATGCAGGTCGATGCCACCGAAGCCATCAACCTAAGCTTCAAACTGTCCCCCTCACCGACTGCGTACAAGCAACCGCTTTACTACGGTGCTTCAATGCCCAGTCAGCGTGGTACAGACATTCCAGCGCCACATCATTACATTCGTCAGACACCGTCACCAAATGAGGCGATGCCACCAACTCAACGGTATCCCTCTAGTCATCCATATATGATGCCCAGTGCGGCCGCTGCCCGTGGTATGGTTCCGATGGAGTGTCTCTTTCAAATGACCCCCGAATATGCCAGGAGTCATCTGATgggaaatattaaaatgaaCGGTGGCAGTGATCGTGGTACAAGCTTGAGTCCTGGATCTGAAAAACGATCATGGCGAGATGATGAATCGAGGATCTCTCATGAAGATGAGTACgtagcggcagcagcagcagcggcgGCGGCTTCCGGTCTAATGCCACCACAACTAAAGCGGACGAAGAACGAGACGCATGGTCATGCTGGTGATCCGGATTTGCCGTTTGTGTGCGATCAGTGTGATAAGGCGTTTGCTAAACAAAGCTCGCTGGCGAGACATAAATATGAACATTCTGGTCAACGTCCTTACAAGTGCGTCGATTGCCCAAAAGCCTTCAAACACAAACACCATCTAACCGAACACAAACGTCTGCACAGCGGTGAAAAACCCTTCCAGTGCTCCAAATGCCTGAAACGTTTCTCACATTCCGGCtcctatagccagcacatgaaCCATAGGTACTCCTACTGCAAACCGTACAGGGAATAG
- Protein Sequence
- MPSSPAFSMQFPSLASSLHHHSQIKNEDSSTASSAATAATTTQQGGGGGGVGDFIVKCPQCPQRLSGFQALHEHLVNEHSHDKFTFENHHNDYHIDREMDYSTGRHDNKQMHNNNNNLNNNNNNNNKNNNNLKLHSISNNNCHSSSSTGSTSLIPNGNGQTSPVPSSHSPLVGASAQQRTTPPTDLSSQYHHHAMAMAALAVGMSTSATAASNGYDASSAAAMAAAEAMAMAGSRSTTSPLNGHNVGNGGGMVNGNCGASTASSSSSTSSMSAGPYQCSQCSAAFPNRDLLEKHELMHSPNSTGVNQSCKICHKAFANVYRLQRHMISHNDSELLRKFKCTQCDKAFKFKHHLKEHVRIHSGEKPFGCDNCGKRFSHSGSFSSHMTSKKCISMGLKLNNNRAMLKSLEKSGVLGGSPNGKRSGQPPAGANPLNYFPHGLGGGGPDGPTNPPNGSNFYQMLPKYSDYGAMNAALLATFQNPFYNMAALNPNIHPYSIHRLLELTAAGNQRLQSDPEDLIEEVTEDVADEPKLVMDLKDDCEKDADVEDDHARTYSRSDDEDDGDSRNSNSSTPQKPNYDDFSAQDMEIPRIRSPSPVPEEERPQSPEIKVEEEDEEKNTSHEEVEPEDDTPLSDLRCSRCDKSFNHPTELVQHEKVLCGLIKHELQQQQQQQHHQQLQHHFQSNESDNGNSSYLHSGSEEELEDRESKNGSEAGERKVRVRTAITEEQQTVLKQHYAVNARPSRDEFRVIANRLSLDARVVQVWFQNNRSRERKMNNSFSKGYPSMIPEPQQPVSPPPPAFESVKEDQPLDLSIKKEKASNQQAAHSPLYGSVPMQVDATEAINLSFKLSPSPTAYKQPLYYGASMPSQRGTDIPAPHHYIRQTPSPNEAMPPTQRYPSSHPYMMPSAAAARGMVPMECLFQMTPEYARSHLMGNIKMNGGSDRGTSLSPGSEKRSWRDDESRISHEDEYVAAAAAAAAASGLMPPQLKRTKNETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYKCVDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01542099;
- 90% Identity
- iTF_01300321;
- 80% Identity
- iTF_01300730;