Rmeg011005.1
Basic Information
- Insect
- Rhimphoctona megacephalus
- Gene Symbol
- topi
- Assembly
- GCA_963989365.1
- Location
- OZ022416.1:16375559-16377496[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 2.7e-05 0.0038 18.4 2.7 1 23 43 65 43 65 0.99 2 14 0.0026 0.37 12.1 0.4 1 23 71 94 71 94 0.94 3 14 0.42 60 5.2 0.9 1 23 100 122 100 122 0.96 4 14 4.4e-07 6.2e-05 24.0 2.2 1 23 128 150 128 150 0.97 5 14 2e-05 0.0029 18.7 2.1 1 23 156 178 156 178 0.97 6 14 0.00066 0.094 14.0 7.1 1 23 184 206 184 206 0.96 7 14 0.00033 0.047 14.9 2.7 3 23 245 266 244 266 0.95 8 14 0.098 14 7.2 1.3 1 14 271 284 271 294 0.84 9 14 1.3e-05 0.0019 19.3 1.3 1 23 377 400 377 400 0.97 10 14 6e-05 0.0085 17.3 1.9 1 23 406 428 406 428 0.97 11 14 1.1e-06 0.00015 22.8 1.9 1 23 434 456 434 456 0.99 12 14 0.0055 0.79 11.1 4.4 1 23 462 484 462 484 0.99 13 14 1.2e-06 0.00017 22.6 1.4 1 23 490 512 490 512 0.98 14 14 0.00012 0.017 16.3 2.9 1 23 518 540 518 541 0.95
Sequence Information
- Coding Sequence
- atGGATCGAGATGAAAATTCCCGAGAGAAACGATATATCACAATAAACAGACGAAGGCTTGTCGTTGAAGCTGAACAATGCGATGAATTGTTACGATCAAAGATCCACGATGGAAATAAGACGCGTTACAAGTGCGAACATTGCGAGAAAATAATATCAACGTCTTATAATTTCATGGCTCATTTGAAAAGGCACAGCGGTGAAAAACCATACGCGTGTTACGTTTGTACGAAAAAGTTTCGCTTCGCCTCGATTCTCAATCGACACGTAAACGCTGTACATCGTGGAGACAAAAAATTTCCCTGTGATCTTTGCGATTGTCGTCTAGCAACGAGAATCTCACGGGACGAACATCGTCGAATTCACACCAACGAAAGGCCACACGTTTGCGAGATTTGCGGCAAAACTTTTAAGCAAAAGGCTTCTCTCAACGTTCACAAACGTTTTCACGCTCGTGATTTTCGGCACAAGTGCCGAATTTGCAATAGATCTTTTGGAAGAAAACAAGATCTGGAAAAACATGAGCTCGTGCACACCGGAGTTAAGCCGCACTGTTGCGAAACTTGTGAaaaacgttttcgaaccgctggCTGTTTGAATCGTCATGCACAGACTCATAAGATTGAAAAATCGTCCCAGGAAGAATTTTACGGAAAAAGGGATACCCTAACAAAGAGCATCGATAAGAGCAACGATATTCTTGTTTACGACGATCAAATGAAAGGCGCGTGTTGCAAAATATGCGATAACAGTTTCTCCCAAATATCCGAGCTCGTCGAACACATGAAACATATACACGACGATCACctttattattgtcattattgTAAAATCGTGTTTCGTGGCCCTGATGAAAGTTTTTACGAGCACGTACGGAATCACGAATATGAGGAGCAAACGAGAAATAACGATGAATCGGAAAACTTGTTATATTTATCCACTGAGAATGATGAGATTAAGCTTGAATCGAATACTCGAGAGATTTGCGATATGCCAACGTCGAGAGAAAACAATGACAATCGGAAAAACACGAAAGCCAATCTTCCCAAAGAGGGCTCAAAAGTTATACTTTTGGATGTACATCATTCCGTTCCCGAAAACATAACGTATGAACCTTCAAAAAGTCCGTACATGTGCGAATTTTGTGGTAAAACGTATTACTCGTTGTTGAATCTACGTACTCATCAGAGAAACGTTCACGCTGGTTTAAAATTGCACATGTGCGATTTGTGCGAGCGTAATTTTGCGTTAAAATCGACACTGGAAAATCATCAACGCTCGCACACAAAAAAATCTCCTTACAAATGtgaatattgtgataaaaaatttcgTACCGCAAATTCAATGTACGTTCATCAACGTATACACGAGGATCGTAAACTATACGTTTGCACCAAGTGCGAAAAGAGATATCTTACGAAACAGTGTTTGTCGGAACATTTGAGGACGCACGAAGATAACACCTCTTATGTTTGTGAAACTTGTGGCAAAAGTTTCGGCTTCAAGAGAAATTTACTTAGACACTTTCGAGTTCACAGTATCGACGAAACTTTCGTTTGTCCGTTTTGTCCCTCCAAGTTTCGACAAAAAAGATATTTGAGAGTACACACGCAGATTCATCATCCCGATAAATAA
- Protein Sequence
- MDRDENSREKRYITINRRRLVVEAEQCDELLRSKIHDGNKTRYKCEHCEKIISTSYNFMAHLKRHSGEKPYACYVCTKKFRFASILNRHVNAVHRGDKKFPCDLCDCRLATRISRDEHRRIHTNERPHVCEICGKTFKQKASLNVHKRFHARDFRHKCRICNRSFGRKQDLEKHELVHTGVKPHCCETCEKRFRTAGCLNRHAQTHKIEKSSQEEFYGKRDTLTKSIDKSNDILVYDDQMKGACCKICDNSFSQISELVEHMKHIHDDHLYYCHYCKIVFRGPDESFYEHVRNHEYEEQTRNNDESENLLYLSTENDEIKLESNTREICDMPTSRENNDNRKNTKANLPKEGSKVILLDVHHSVPENITYEPSKSPYMCEFCGKTYYSLLNLRTHQRNVHAGLKLHMCDLCERNFALKSTLENHQRSHTKKSPYKCEYCDKKFRTANSMYVHQRIHEDRKLYVCTKCEKRYLTKQCLSEHLRTHEDNTSYVCETCGKSFGFKRNLLRHFRVHSIDETFVCPFCPSKFRQKRYLRVHTQIHHPDK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -