Basic Information

Insect: Rhaphigaster nebulosa
Gene Symbol: hb
Assembly: GCA_948150685.1
Location: OX411309.1:99603913-99607686[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00067 0.14 14.0 1.2 2 23 152 173 151 173 0.97

2 8 0.0029 0.62 12.0 0.7 2 23 176 198 175 198 0.96

3 8 0.03 6.4 8.8 1.0 1 23 225 247 225 247 0.98

4 8 0.0015 0.33 12.9 3.1 2 23 255 276 254 276 0.97

5 8 7.1e-05 0.015 17.1 4.5 1 23 282 304 282 304 0.99

6 8 0.029 6.2 8.8 5.1 1 23 310 334 310 334 0.93

7 8 0.0004 0.085 14.7 0.6 1 23 516 538 516 538 0.96

8 8 0.0021 0.44 12.4 0.6 1 22 544 565 544 568 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00067	0.14	14.0	1.2	2	23	152	173	151	173	0.97
2	8	0.0029	0.62	12.0	0.7	2	23	176	198	175	198	0.96
3	8	0.03	6.4	8.8	1.0	1	23	225	247	225	247	0.98
4	8	0.0015	0.33	12.9	3.1	2	23	255	276	254	276	0.97
5	8	7.1e-05	0.015	17.1	4.5	1	23	282	304	282	304	0.99
6	8	0.029	6.2	8.8	5.1	1	23	310	334	310	334	0.93
7	8	0.0004	0.085	14.7	0.6	1	23	516	538	516	538	0.96
8	8	0.0021	0.44	12.4	0.6	1	22	544	565	544	568	0.91

Sequence Information

Coding Sequence: ATGTATTCTTTGACCACCGTTAAGCCAGATGCCAGTTGGAATGAGATGATTATAACTCCTGATATATACTTTAACAATCCGAGGATGAACATCGGTGTGCAATACGATCCTAGGCATTCTGTCTTTCCCAATTTGGACCACCATCCATGGATGGCATCTCCGACTCCAGCTCAGGTCGTTAAAGAGGAGCCGCGTGACGACGCCGAGTATGGGCAAAACGCTCAGGACAGCCGGCTGCCGCTGACACCACCCCCCTTCCAGGGCTACCCTCCAGCGAACGCCTACCGCGACGCCACGCCCCCCAAGGACACGCCCCCCGCCTCCACGCCCTCGCCGCAGGAGAAGCAAGAGGGCAGCTCTAACTCCGAAGGAGAGTACTATGAGAGCGGGGACTCCCTTAAGAGGCTTCAGATGGCCCTTCATAGGACTGGCATGATAACTGAAGAGAAGCTGCAATGCCCTGTCTGCGAATTTTCTTGCAGCGTCAGATCCCAGTTTAATGAGCACCTGTTGTCACATGAAACTAAATGTTCCATGTGCGATTTCAATGGAGAAACCAGTGAGAAGTTGAGAGAACATATGCGAAATGTCCATGACTGCGATGATGACAGCACCTGGGGCGATGATGAACTCAATACCCCCAAAGTGAATTCTCAGGGGAAAGTCAAAACGTTCCGGTGCAAACAATGTGAGTTTTCAGCTGTGACAAAACTTGAATTCTGGGAACATTCTCGTACCCATATTAAACAAGAGCGCCTACTCACTTGTCCCAAGTGCCCATTTGTGACCGAGTACAAACACCATCTGGAATATCATTTGAGGAATCATTTTGGATCGAAACCGTTTAAATGTGACAAATGTTCTTATTCTTGTGTAAACAAGTCTATGCTCAATTCTCATTTGAAAAGTCACAGCAACATTTACCAGTTCAGATGTGCTGATTGTACCTATGCTACTAAATATTGTCACAGTTTGAAGCTGCATTTAAGAAAATATGCTCACAGTCCAGCCATGGTCTTAAATCCTGATGGTTCTCCTAATCCATTACCTATTGTAGATGTCTACGGTACCAGGCGTGGTCCAAAACAGAAGCCTAAGCAAGACCAACAACAGCAGCAACCTCAAGTCCCTAATATCTTCAACCCTTATACTTTACTTCCAACACAGATGCCATATTATAATATTCTTAATGGATTTGGAGGGTTTCCTTTCCCTCAAGATGTAAACATGGAAGAAAAGAATAACAACGTTGAGAAAGAAGAAGTCAGAGAAGAGAAAGCTCCTCTTGATTTGAGCTGTCCTGAGCCGATGGTCGAAGACAGCAATCAAGAGGCTCCAGTTAAAAATAGGAGAAAAGGAAAAGCTTTCAAACTTGACAGAATCGCTCTTCGTCTTCAGCAGCAAGTTGAAGTGGATGAACAGCAGCCAGACTTGCAACAGCCGACTCCACCTCCTGTGGTTTCAGAGCCTGCAAAATCACCAGAAATCAAGTCCTGTGAAGCAGACAGTGAACAGAAGACAGAGAAGACAGAATCAAAAGATGACTATAACTGCACTTATTGTGATATTTCATTTAAGGACATTGTGATGTATACAATGCATATGGGTTATCATGGTTATGAGGATCCTTTTAAGTGTAACATGTGTGGGCAGCAAACAACGGATAAGGTCGCTTTCTTTCTTCATATTGCAAGAACATCACACTCATAA
Protein Sequence: MYSLTTVKPDASWNEMIITPDIYFNNPRMNIGVQYDPRHSVFPNLDHHPWMASPTPAQVVKEEPRDDAEYGQNAQDSRLPLTPPPFQGYPPANAYRDATPPKDTPPASTPSPQEKQEGSSNSEGEYYESGDSLKRLQMALHRTGMITEEKLQCPVCEFSCSVRSQFNEHLLSHETKCSMCDFNGETSEKLREHMRNVHDCDDDSTWGDDELNTPKVNSQGKVKTFRCKQCEFSAVTKLEFWEHSRTHIKQERLLTCPKCPFVTEYKHHLEYHLRNHFGSKPFKCDKCSYSCVNKSMLNSHLKSHSNIYQFRCADCTYATKYCHSLKLHLRKYAHSPAMVLNPDGSPNPLPIVDVYGTRRGPKQKPKQDQQQQQPQVPNIFNPYTLLPTQMPYYNILNGFGGFPFPQDVNMEEKNNNVEKEEVREEKAPLDLSCPEPMVEDSNQEAPVKNRRKGKAFKLDRIALRLQQQVEVDEQQPDLQQPTPPPVVSEPAKSPEIKSCEADSEQKTEKTESKDDYNCTYCDISFKDIVMYTMHMGYHGYEDPFKCNMCGQQTTDKVAFFLHIARTSHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00715384;
90% Identity: iTF_00715384; iTF_00764219;
80% Identity: -