Basic Information

Insect: Rhaphigaster nebulosa
Gene Symbol: Zfy2
Assembly: GCA_948150685.1
Location: OX411306.1:43258848-43292543[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.00086 0.18 13.7 1.4 3 23 54 74 53 74 0.98

2 19 4.5e-06 0.00094 20.9 2.0 1 23 80 102 80 102 0.97

3 19 0.22 46 6.1 4.5 1 23 109 131 109 131 0.98

4 19 0.00055 0.12 14.3 0.5 3 23 140 160 139 160 0.97

5 19 0.00013 0.027 16.3 3.9 1 23 166 188 166 188 0.98

6 19 0.0013 0.27 13.1 0.5 2 23 201 223 201 223 0.95

7 19 2.9e-06 0.00061 21.5 5.4 1 23 229 251 229 251 0.99

8 19 0.011 2.2 10.2 1.7 1 23 257 279 257 279 0.97

9 19 0.0012 0.25 13.2 1.9 1 23 286 308 286 308 0.98

10 19 0.49 1e+02 5.0 7.7 1 23 314 336 314 336 0.98

11 19 3.8e-06 0.0008 21.1 5.9 1 23 342 364 342 364 0.99

12 19 0.039 8.3 8.4 0.1 1 23 486 508 486 508 0.95

13 19 0.0097 2 10.4 0.3 2 23 642 663 642 663 0.97

14 19 0.0015 0.32 12.9 3.3 1 23 669 692 669 692 0.96

15 19 0.00011 0.022 16.5 1.7 1 23 701 723 701 723 0.97

16 19 0.0069 1.4 10.8 0.1 3 23 732 752 730 752 0.97

17 19 0.00066 0.14 14.0 4.5 1 23 758 780 758 780 0.99

18 19 0.034 7.2 8.6 0.3 1 23 791 813 791 813 0.97

19 19 9.1 1.9e+03 1.0 2.3 1 23 821 843 821 843 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.00086	0.18	13.7	1.4	3	23	54	74	53	74	0.98
2	19	4.5e-06	0.00094	20.9	2.0	1	23	80	102	80	102	0.97
3	19	0.22	46	6.1	4.5	1	23	109	131	109	131	0.98
4	19	0.00055	0.12	14.3	0.5	3	23	140	160	139	160	0.97
5	19	0.00013	0.027	16.3	3.9	1	23	166	188	166	188	0.98
6	19	0.0013	0.27	13.1	0.5	2	23	201	223	201	223	0.95
7	19	2.9e-06	0.00061	21.5	5.4	1	23	229	251	229	251	0.99
8	19	0.011	2.2	10.2	1.7	1	23	257	279	257	279	0.97
9	19	0.0012	0.25	13.2	1.9	1	23	286	308	286	308	0.98
10	19	0.49	1e+02	5.0	7.7	1	23	314	336	314	336	0.98
11	19	3.8e-06	0.0008	21.1	5.9	1	23	342	364	342	364	0.99
12	19	0.039	8.3	8.4	0.1	1	23	486	508	486	508	0.95
13	19	0.0097	2	10.4	0.3	2	23	642	663	642	663	0.97
14	19	0.0015	0.32	12.9	3.3	1	23	669	692	669	692	0.96
15	19	0.00011	0.022	16.5	1.7	1	23	701	723	701	723	0.97
16	19	0.0069	1.4	10.8	0.1	3	23	732	752	730	752	0.97
17	19	0.00066	0.14	14.0	4.5	1	23	758	780	758	780	0.99
18	19	0.034	7.2	8.6	0.3	1	23	791	813	791	813	0.97
19	19	9.1	1.9e+03	1.0	2.3	1	23	821	843	821	843	0.88

Sequence Information

Coding Sequence: ATGACGGTGAACAGTAGAATGTGTGTCGATCCAAGTTTTCCTGCTAATTCTTCAACTGTTATACCAGGATTTTCTTCAACAGTAGCCTGCAGGAGTTCGTCGCCAAGCTCTATTGGTCGACCTGCCCGAGACTCATTTTCAAATGAAAGGCTCAATCTCTGTCCATATTGTGATTACCGTACATACAATGTGGGCCATTTCAAAGTTCATATGAGACAACACACAGGGGAAGCGCCGTTTGCGTGTGAATATTGCCCATATCGCTCTAAGCAGAAGTCAAATTTAAAGAGGCACTTAAGGCAACATCTTGAAGGAAAAGATAATTTTGAATGTGAAATGTGTTCATTCACTTGTACGAAAGAAAAAGTCTACAAACGGCATTTGAAATTGCACCAGCGTTCACGGCCATTGAGGCCATGTCCATTCTGTGATTATTTCTCTTCAAGTCTTGCTCATCTAACTGTGCATATAAGACAGCATACAGGAGAAACTCCTTACCATTGTGGTGTGTGCCAATACAAAACAGTTCAAAAATCAAATCTTACTAGACACTTGAAAAAACATCGCCATCACCGTGTAAGCAAAGCTGATAAACTGCGTGTATGTGCACATTGTAATTACCGAACTCCTAACTCTGCACACTTATTGGCCCATATTAGGGCTGCTCATACTGGAGAAGCTCCATATAGTTGTAAGCATTGTGATTATAAGTCAGCTCAAAGATCAAATTTGAAGAGGCACATGAGAAAGCATACAGGCGAACGCCCATTTTCATGCCATCTTTGCAGTTATTCTACTGCATATGCTTATGTACTGAAAAAGCATATAGAAAATCACCCGGAACAGGAAGAGAAATTCAATTGTGATTCTTGTGATTATTTTACTAACTCATCTGTTGAATTTAAAAGACATATAAAAACACATAGTGGAAGATCTATGTATTGTTGTCACTTTTGTGGTTATATTTCTCTTAACTCAGATCATTTTAAGGTTCACTTACGAAGACATACCCAAGAAGCCCCTTATCAGTGCCATCATTGTGACTATAGATCGGCTCAGAGATCTAACCTCAAGAGACATATTCAGACGCACACTGAAGAAAACAAATGGAGTAAAGATATTGAAAATAGTAACGAAACACAACATGTTATGGAATCTGAAATTTCTGTTTTGGATGTGGAATCAAATGAAGTTGTAGATAATTCACAAACACTAAGAGAAAATGATATTCCTGAGAATGTTCAAATAATTGATACTACTAATGTTGGACATGAAGATGTTGAGATTTATGAGTCAGAGGAAGGCTATGTTGAGGCAGAGTATAGTCCAGATGGAGAAATAGAAGAAGCTGCTAATACACTCCCAGAGTCAACTATGGAAGTTGTTGGCGAAGAGCATGTCATTACTACTCCAACAGAAGGTGAATATGATGTTTATAAAGATTGTGGAAAAATCTATCTCTGTTCTTACTGCTCCTACCAATCATCCAGTGCTGAAGATATTCAAGCTCACATACAAGAGCACGATGGTACTCTTGTTAACGGTGTTGAAGCTACAGAAAATGAAATATCTGAATCAGATGGTGTAAAAACGAATAATATTAGTTTTCTTAACAAATCACAAACTGAAAAACTGAAAGAGTTCAAACGCCTTTTGCAGGAAGgCACAGGTGGAAGTGCTCCAAATGTGGTCCATGTTGCAAAGTTACCTCAACAACAAATTGAAGCTGGAAGAGATGAATATTATCGACAATCTGTTGAACCTGCTGAATACAGAAATCAACCTTCTCCAGAAGAAGTGACCTTGTATGGAGAAGTAGAAGAGAATTACGAACAGGAGGAAACAATCGATCAGGATGCTGCATTAAAAGATTCATCTGTCATAATTGTTGGTACTCCTGAAGAATTGAAACAAACAACAAATGAGTGTGAACTGTGTGGTTTTCACGCAAGAACTATTTGGGAACTTAAATCTCATATAAGAGTTCATACTGGTGAAATGTCGTTTGTTTGTCCTCAGTGTCCCTTCAAAACAAATCAGAAATATAGTTTTCAAAGGCACGTGAGACACCTGCACGGTTGGAGAGGCAATAGGCCTCCTTATCAATGTAAATTATGTGACTTTAGGACAAAAAATAAAGAAAATCTTATCAAGCATGCGCAAAATCATTCAAAAAAGATGCCATCTATTGACTGTAATATATGTGAGCAAACGTTGGGATCAATTGCAGAATTAAAAAGCCACATGAAAATACATATTGGTGAAGCACCTTATGAATGTTTCTATTGTGGAAAACTGACTGCTCGTAAACTTCATATGAGAAGACATATGAAGAAACATATTTGTACAATGGAAGGAAAAGGACCACCTTACGATTGTGATTCTTGTGGTTACCAAACTGTTTTTGAAGTAAATTACTTAAGGCATTTAGAAACGCATGAATTGGATCCTCCTAGAGCTTTCATATGCCATTATTGCCGTTTTGTCACATTAGATAATAAAGTATTCAAGAAGCATCTTGCAGATCATAAGAATCCAGGGTCTGGAGAATTAGACAATCTCTTAATCGCAGAAGAAACAGAGAGTGATTCAGTGAATAATAATGATGCTGATGATACCAGCAAACATAAAAGgaaaCCTTTACGCGAACACAACACATCCATTGATGAGGCTTTTGAAAAATCTGAAAAAAATTATACTTATACTCCTTTGCTGAAGCAAGGCAAAATAAAAAATTTGGAAACCACAAGTTCTTCAAGTAAATCAAAATTTAGATCAAAAAGATCTTCGAATTCTACCATCATCAAAAAAAGGGAATATATCAGGCGTGCTGGAAATATTTCTGAATCAGAGTTGAGGATCAGGCGGAGATTGGATTTTGGTATCAAGAAAGTCCCTAAAGATCCGAAAGAAGGTTTTACTGTTGAAATATGTGGTGAAATCTTGAAATCGAAACGTCAATTAAGAGATTTCTCTGATTATGGGAAGTTAATCAAAAGATCAGATTTAGATCTTTCAACTGTATTAGAAAAGGAGTCGCATATAGAAAATATGTTTGTGCCGTTAAGGGAAAGCATTCATGCATTAAAAGAGCTAAAGAATAGTGATGATAATGTAGTCACGTTCACAATCTATTTTAAAACTAAAGATGAGCCCGACCCTGTTGATATTAGTGATAATATGACTGATATTGAGGCAGAACTGTTATCTGACTCAAATGACACCGACATTGATTCTCTCAAGTCAGATGATGAACTATTGACACCAATGGATTTATTGGATGGCGATAAAAATGGTTCTTTTGATGAAGTGAAAGCATCAAGAAAGGAATTAAATCATAATGATAATGGTATTTCATCAGCGAAACAAACATCTAACAGGAAAAAATTGCCCTTAAGTTCTGGTATTGATACAATTAGGTTCTTTCAAAATAAAATTAAGGAACGGAATGCAAAAATGAAACAAATGAGGCGGCTCAAAGTTTTAAGGAACACAATTAACTGGAATAAAAATGGTACTAAGTCGGAATCAGTTAGTTCAAAAAATTGTGTCCAAGTTGAGTATTCTTATAGTGACAATGTGGAGATGGAGGAAGTTGTGGTTGACCACAATATTGATGCATTACCTAGTCTTGTATCATAA
Protein Sequence: MTVNSRMCVDPSFPANSSTVIPGFSSTVACRSSSPSSIGRPARDSFSNERLNLCPYCDYRTYNVGHFKVHMRQHTGEAPFACEYCPYRSKQKSNLKRHLRQHLEGKDNFECEMCSFTCTKEKVYKRHLKLHQRSRPLRPCPFCDYFSSSLAHLTVHIRQHTGETPYHCGVCQYKTVQKSNLTRHLKKHRHHRVSKADKLRVCAHCNYRTPNSAHLLAHIRAAHTGEAPYSCKHCDYKSAQRSNLKRHMRKHTGERPFSCHLCSYSTAYAYVLKKHIENHPEQEEKFNCDSCDYFTNSSVEFKRHIKTHSGRSMYCCHFCGYISLNSDHFKVHLRRHTQEAPYQCHHCDYRSAQRSNLKRHIQTHTEENKWSKDIENSNETQHVMESEISVLDVESNEVVDNSQTLRENDIPENVQIIDTTNVGHEDVEIYESEEGYVEAEYSPDGEIEEAANTLPESTMEVVGEEHVITTPTEGEYDVYKDCGKIYLCSYCSYQSSSAEDIQAHIQEHDGTLVNGVEATENEISESDGVKTNNISFLNKSQTEKLKEFKRLLQEGTGGSAPNVVHVAKLPQQQIEAGRDEYYRQSVEPAEYRNQPSPEEVTLYGEVEENYEQEETIDQDAALKDSSVIIVGTPEELKQTTNECELCGFHARTIWELKSHIRVHTGEMSFVCPQCPFKTNQKYSFQRHVRHLHGWRGNRPPYQCKLCDFRTKNKENLIKHAQNHSKKMPSIDCNICEQTLGSIAELKSHMKIHIGEAPYECFYCGKLTARKLHMRRHMKKHICTMEGKGPPYDCDSCGYQTVFEVNYLRHLETHELDPPRAFICHYCRFVTLDNKVFKKHLADHKNPGSGELDNLLIAEETESDSVNNNDADDTSKHKRKPLREHNTSIDEAFEKSEKNYTYTPLLKQGKIKNLETTSSSSKSKFRSKRSSNSTIIKKREYIRRAGNISESELRIRRRLDFGIKKVPKDPKEGFTVEICGEILKSKRQLRDFSDYGKLIKRSDLDLSTVLEKESHIENMFVPLRESIHALKELKNSDDNVVTFTIYFKTKDEPDPVDISDNMTDIEAELLSDSNDTDIDSLKSDDELLTPMDLLDGDKNGSFDEVKASRKELNHNDNGISSAKQTSNRKKLPLSSGIDTIRFFQNKIKERNAKMKQMRRLKVLRNTINWNKNGTKSESVSSKNCVQVEYSYSDNVEMEEVVVDHNIDALPSLVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00764036;
90% Identity: iTF_00764036;
80% Identity: -