Basic Information

Insect: Rhaphigaster nebulosa
Gene Symbol: ZNF219
Assembly: GCA_948150685.1
Location: OX411308.1:26504525-26527192[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.014 3 9.8 1.3 1 21 115 135 115 136 0.94

2 12 2e-05 0.0041 18.8 1.7 2 23 157 178 157 178 0.98

3 12 1.8e-06 0.00038 22.1 0.8 1 23 184 207 184 207 0.96

4 12 0.0013 0.27 13.1 0.9 1 23 213 235 213 235 0.90

5 12 9.1e-05 0.019 16.7 0.5 1 23 241 264 241 264 0.96

6 12 0.00074 0.15 13.9 0.3 2 23 270 291 269 291 0.97

7 12 0.00013 0.027 16.2 0.3 2 23 296 318 295 318 0.94

8 12 2.5e-05 0.0053 18.5 0.7 2 23 323 344 323 344 0.98

9 12 0.00082 0.17 13.7 0.3 1 23 350 372 350 372 0.91

10 12 7.1e-06 0.0015 20.2 0.2 1 23 378 400 378 400 0.98

11 12 8.5e-05 0.018 16.8 3.4 2 23 406 427 405 427 0.97

12 12 0.00011 0.024 16.4 1.6 3 23 438 459 436 459 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.014	3	9.8	1.3	1	21	115	135	115	136	0.94
2	12	2e-05	0.0041	18.8	1.7	2	23	157	178	157	178	0.98
3	12	1.8e-06	0.00038	22.1	0.8	1	23	184	207	184	207	0.96
4	12	0.0013	0.27	13.1	0.9	1	23	213	235	213	235	0.90
5	12	9.1e-05	0.019	16.7	0.5	1	23	241	264	241	264	0.96
6	12	0.00074	0.15	13.9	0.3	2	23	270	291	269	291	0.97
7	12	0.00013	0.027	16.2	0.3	2	23	296	318	295	318	0.94
8	12	2.5e-05	0.0053	18.5	0.7	2	23	323	344	323	344	0.98
9	12	0.00082	0.17	13.7	0.3	1	23	350	372	350	372	0.91
10	12	7.1e-06	0.0015	20.2	0.2	1	23	378	400	378	400	0.98
11	12	8.5e-05	0.018	16.8	3.4	2	23	406	427	405	427	0.97
12	12	0.00011	0.024	16.4	1.6	3	23	438	459	436	459	0.96

Sequence Information

Coding Sequence: ATGGACCTGGCTTCCAGTTCTCTAGATTCTGTGAAACATGAGAACTCAGATGAATTAATGTTTAGTGAGGATGAAGATGATATTCCCAGATGTGGTGTTTCTCTTAATGAACTTAAAACCAAAATAAAAACGGAATACTCATCAAACAAAGAAGAGGAAGACAATAATGTCCAGAGCAAAGATGAAGAAAATGACAGTATTCCTTTAACCACCAAAAAAGAAGTGGAAGAAGATTTGGAGGTGGAACTGAAAGTCAGCCGCTTCTTGGAAAATCCAGATGTTGATGTTAAGAGAACTCGTAAAAGAAAAGGGAAAAAAAAGTCAACAAAATCAGCTTGTAAATTTAAGTGTAATCAGTGCAGTGCATTGTTCCGTTACAAGTCAACTCTGTCCTACCATGCAAAATCTGGCTGTGGGCGTGGTCTTCTTTCCAGCCAAGGGGGTGTTGTAAAATCCTCTGGATCTGCCACCTGTCATATTTGTGGAAGACGATTATCCTCACGTACTAGTTTGATGGTTCACCTTAGGATTCATACAGGTGAAAGGCCTTTCAAGTGTGGTGAATGTGGTCAAGCGTTTACTCAAAATGCTCACCTAAAAGATCACACTGCTAGATTGCACTCAGAAGGGGAAATATTTCTTTGTCGCATCTGCAATAAGACTTTTCCTAACCGAGGGAGACTGAGGGAGCATTCTACTGAACATGAAAGTCTGCGTGGCTTTCAGTGTCAGGAATGCAGTAAAAGGTTTCCAACTGAGGAAAGGCTTGAATCCCATAAACGTGCTGGGCATGAGAGCAAACCGCAGTCGTGTCCTCTCTGTGGAGCAGCTTGTGAATCGCGTGTCGCTCTCAAATCTCACCTTTCTACGCATTCTCCACCCCTTCGCTGCCCTCTTTGTGATCAGTCATTTCCGAGTTTGTCCTCATGGAGACAACATGTTACTAGGCAGCACAGAGCTTCTAGAAAATGTGGGTATTGCGAAAGAACATTTTCATCAGATTATGATCTAAGGGTCCATGAGCGATCACATACGGGAGAGCGGCCATTTCCTTGTGAGTTTTGTGGTCGTGCTTTTTCTAGGAAGTCCATTCTTGGAGTACATAGAACCTTGCATACTGGGCAACGAGATTTTGTTTGTTCTCAGTGTGGAATGGCATTTAATAGAAAATCCAAATTAGATGTTCATATTGCATCTCACCTTCACACAGCTCTCCCTTGCCAGGTATGTAATAAAACTTTTAAATGCAAAGCATACTTGACATCTCATATGAAGACCCATGGAAGGCAGGAGGAAGTTGGAAATGTTATTTGCCATAATTGTGGTAGGGCATTTGGTTCAAAGCGAGGTTTGCTTCACCATCAAGCAACCCAACATCCATTGCCTATCAAAGAAGAGTTCTTTCAAGCAACTTTATTTAATTCATTTATTAAGCAGGAGCCATATGTGTTACCAGATGAAACTTCTTATTTAAACATTAAACAAGAGCCAGTTGCACAGCCAATTTTAGGTGCAGAGGTTTGCCTCTGGGTTAAAAGTTGCTGGTATCAAATGATATCAAATTCACCCAGAAAAATAAAGGTTTTGTGTAAAAGACTTTAA
Protein Sequence: MDLASSSLDSVKHENSDELMFSEDEDDIPRCGVSLNELKTKIKTEYSSNKEEEDNNVQSKDEENDSIPLTTKKEVEEDLEVELKVSRFLENPDVDVKRTRKRKGKKKSTKSACKFKCNQCSALFRYKSTLSYHAKSGCGRGLLSSQGGVVKSSGSATCHICGRRLSSRTSLMVHLRIHTGERPFKCGECGQAFTQNAHLKDHTARLHSEGEIFLCRICNKTFPNRGRLREHSTEHESLRGFQCQECSKRFPTEERLESHKRAGHESKPQSCPLCGAACESRVALKSHLSTHSPPLRCPLCDQSFPSLSSWRQHVTRQHRASRKCGYCERTFSSDYDLRVHERSHTGERPFPCEFCGRAFSRKSILGVHRTLHTGQRDFVCSQCGMAFNRKSKLDVHIASHLHTALPCQVCNKTFKCKAYLTSHMKTHGRQEEVGNVICHNCGRAFGSKRGLLHHQATQHPLPIKEEFFQATLFNSFIKQEPYVLPDETSYLNIKQEPVAQPILGAEVCLWVKSCWYQMISNSPRKIKVLCKRL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00757507;
90% Identity: iTF_00764021;
80% Identity: -