Basic Information

Gene Symbol
CalpC
Assembly
GCA_963920725.1
Location
OY987255.1:139648259-139651007[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 6.2e-05 0.0072 17.8 0.8 2 23 438 460 437 460 0.97
2 7 0.26 30 6.4 6.2 1 23 466 488 466 488 0.98
3 7 1.5e-07 1.7e-05 26.0 2.4 3 23 497 517 496 517 0.98
4 7 2.4e-05 0.0027 19.1 1.2 1 23 523 545 523 545 0.95
5 7 0.039 4.6 8.9 0.7 1 23 552 574 552 574 0.98
6 7 7.8e-06 0.0009 20.6 3.6 1 23 580 603 580 603 0.97
7 7 0.021 2.5 9.8 1.5 1 23 609 632 609 632 0.94

Sequence Information

Coding Sequence
atgttatttttggcCGAGTCCGAaaCTATTAATTGTTTTGAATTACAAGAACTCCTAGAAGCATGCTTACCAAATGATTATATTAAAGGTTGTGCAAATATTGATATTTGTCGGCAAATAATAGCCTTACAGGATaaaACTGGAACTGGTCGTATAAATTTCttacaatttaaaacatttatgattaatttaaaatcatggCAAGgtgtctttaaaatatatacaaaagagAAAGCTGGTGTACTTAGATCAGAACGTTTAAGGGATGCATTATGTGATGTTGGTTTTCAATTAAGTACAGATATTATGACTAAAATATATATGCTAGAAGCaagaatcaaaaatattttattagctaatttaccattattaattttcgttatttatcATATTGATGATGATGCACCagacgaaaataatttattacacatatttgaaattggtgcaatgacaataaaaaatgaaaatggtaaaGATATACGTTTAATAGATATGATAATATCAACAACaggattaataattaatgaaaatctaaatgacaattatgatgataataatttgccactacaaatttgtaataattgtattCAAAATGTTAGTaatgcatatttatttaaaatacaatcacAACAAGCAAATGAAActctaaacaaaatttgttcTGAATTGGATTGTAACAGAAATGAAGTCAAAACAAATATAGATAATTTACAAGTTTCTAAACCATTTGAAATAATTAGAGATGGCACTAATATATTTGTTGAAAATGATGAGAACATTAAACAGATTTGTTTTGAGAAAATGGAAACTATAGAAACTAGTACAGATGATTTATTAGATGAACGTGATGATgatgaattggaaaaaaaaaatcttcaagttatagaaattgaatacgaagaaattatttatgacagtaataatgttttaatagaAGAAGAACCAGTAATAAAACATGAATATCAAGGTTTACAAAATGAAGTTGAATTAAATGAGCAAGAAGAATATCAAAAActagaaaatgaaattgaaccgtataatgataatattgataGTGAATCATATACTGAACCAGAAAATTCTCAAAGGcaagttttattttaTGATTCAGTATTTATTAAGTCATTTGTAAGaaattccatacaaaataacgaaGAAGATTATCAAagattagaaaataatgaagctgaactaataaataatgaaaatatagataGTGAACCATATATAGAACCAGAAAATTCTCAAAGtgattCACAATTTCCTAAATCATCtgtaataaattcaacaaaatcagGTCAACTAAATCTTCAGTGCCCCGAATGTTTTGAAAAGTTCACTACAAAGAAACGTTTAATCGATCATGTTCGTACACTTCATCCAAATGTTAAAGCTTTTGAATGTGAAACATGTCATCAGAAATTCCTATTACATCAAACATTAAAACGTCATCAGAAAATCCATCAAGCCAaccaaaaagataaaaattgtaatttctgtGATAAGAGTTTTACACGTAATGATGATTTAAAACGTCATGTTCGGACACATACTAATGAACGTCcatatttatgtacattttgTTCGAAAAGTTATAAACAAAGTTCTGAATTAAAAGAACATTTACTTATACATACCGAAAATCGTCAAATTTACACATGTACAATTTGCTCAAAGACGTTATTAAGTCGTAACGGAATGTATGTACATATGAAAGTACATGCAAATATACGGAatcataaatgtaataaatgtaataaggAATTTGTTACATCAGGTGAATTAACATCACATATACGACATATTCATACGGATCGAGAACgttttttatgtgaaatttgtcgaatgtattttaatacaataaaaacattaaaatcacaTTGGAATCGTCGTCATACTGAGAGTatgaatgtaaaattatttaatgataataatacagaaaaatcttcagatataattagtaaaaaagatgaaaatttaaatgataatagtTGTGGTGGTGATGGTGATTTTAGTAACAAGAATGGAGCAATTGCTCTAATTCAGTGTGGTGAATTAGAAAACTTTTTAGCTAGTTAA
Protein Sequence
MLFLAESETINCFELQELLEACLPNDYIKGCANIDICRQIIALQDKTGTGRINFLQFKTFMINLKSWQGVFKIYTKEKAGVLRSERLRDALCDVGFQLSTDIMTKIYMLEARIKNILLANLPLLIFVIYHIDDDAPDENNLLHIFEIGAMTIKNENGKDIRLIDMIISTTGLIINENLNDNYDDNNLPLQICNNCIQNVSNAYLFKIQSQQANETLNKICSELDCNRNEVKTNIDNLQVSKPFEIIRDGTNIFVENDENIKQICFEKMETIETSTDDLLDERDDDELEKKNLQVIEIEYEEIIYDSNNVLIEEEPVIKHEYQGLQNEVELNEQEEYQKLENEIEPYNDNIDSESYTEPENSQRQVLFYDSVFIKSFVRNSIQNNEEDYQRLENNEAELINNENIDSEPYIEPENSQSDSQFPKSSVINSTKSGQLNLQCPECFEKFTTKKRLIDHVRTLHPNVKAFECETCHQKFLLHQTLKRHQKIHQANQKDKNCNFCDKSFTRNDDLKRHVRTHTNERPYLCTFCSKSYKQSSELKEHLLIHTENRQIYTCTICSKTLLSRNGMYVHMKVHANIRNHKCNKCNKEFVTSGELTSHIRHIHTDRERFLCEICRMYFNTIKTLKSHWNRRHTESMNVKLFNDNNTEKSSDIISKKDENLNDNSCGGDGDFSNKNGAIALIQCGELENFLAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-