Basic Information

Insect: Rhamphomyia laevipes
Gene Symbol: ZFX
Assembly: GCA_963920725.1
Location: OY987255.1:133033901-133035361[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 9 1e+03 1.5 0.1 5 13 26 34 25 36 0.86

2 12 2.6 3.1e+02 3.2 2.8 1 23 38 63 38 63 0.91

3 12 0.00046 0.054 15.0 1.4 1 23 187 209 187 209 0.98

4 12 0.00081 0.094 14.3 2.1 2 19 215 232 215 235 0.93

5 12 4.4e-06 0.00051 21.4 1.2 2 23 256 277 255 277 0.96

6 12 6e-06 0.0007 20.9 3.7 1 23 282 304 282 304 0.99

7 12 3.6e-05 0.0042 18.5 0.4 1 23 310 332 310 332 0.98

8 12 0.0035 0.4 12.3 0.8 1 23 338 361 338 361 0.95

9 12 0.0051 0.59 11.7 3.9 1 23 367 390 367 390 0.97

10 12 8.3e-05 0.0096 17.4 0.4 1 23 398 420 398 420 0.97

11 12 0.0023 0.26 12.8 0.2 1 23 426 448 426 448 0.96

12 12 4.4e-05 0.0051 18.2 0.4 1 23 454 476 454 476 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	9	1e+03	1.5	0.1	5	13	26	34	25	36	0.86
2	12	2.6	3.1e+02	3.2	2.8	1	23	38	63	38	63	0.91
3	12	0.00046	0.054	15.0	1.4	1	23	187	209	187	209	0.98
4	12	0.00081	0.094	14.3	2.1	2	19	215	232	215	235	0.93
5	12	4.4e-06	0.00051	21.4	1.2	2	23	256	277	255	277	0.96
6	12	6e-06	0.0007	20.9	3.7	1	23	282	304	282	304	0.99
7	12	3.6e-05	0.0042	18.5	0.4	1	23	310	332	310	332	0.98
8	12	0.0035	0.4	12.3	0.8	1	23	338	361	338	361	0.95
9	12	0.0051	0.59	11.7	3.9	1	23	367	390	367	390	0.97
10	12	8.3e-05	0.0096	17.4	0.4	1	23	398	420	398	420	0.97
11	12	0.0023	0.26	12.8	0.2	1	23	426	448	426	448	0.96
12	12	4.4e-05	0.0051	18.2	0.4	1	23	454	476	454	476	0.97

Sequence Information

Coding Sequence: atgtcAACAGACATTAAAGTAGAATTGTTATCTGAGGATTTGGAAAATGATATTCCAACATTTAACCAATCTGATAAATGCGGAGAAGTTTTTGTAACAAAAAGAggaatattttcttgtttttgcattgtttgcaaacaaaattttgaGGAAATTAACCATTTTAcggaacatattttattattacatctTGATTTAAGTTCAgctcaaaataatttatttaatttaatacaaaataataatgtagaagTTGATGATATATCCAAGACTTCAATTCCtcataatttattggaaattaaaaagGATGATGTGGAAAATATAAACACAGATTGCTTAAAAATATTGAggaaaaaaatcgaaattactTTGGATGTATTTGATCCACTAAATTTAGAATATGAAGAAGATATCAAAGTCGAAACTGAATCATCTGGAAGAGAAATTTTCTGCGAAAAAGAAGCCAGTACCATAGCAAAAGTAGGTGATTGGAATTCACGAAATTCTGATGATGAAGAAACATTtgatttcaatgaaaatgaaatggaTGAGAAGTTTCCTTTTAAATGTGACATTTGTAATAGGTCGTATAAACTTAAAAACGCATTTGTTGCTCATAAAAAGCTACACGAAAATGTAATACCTAGTTGTTCACATTGTGGCAAGAATTTTGGAGATAAACAGTCATTTAAAAGACATAATCAAGAACTATGTGCACAACGAAAAGAACTTGGTGTTAAAAATACATCAAAAGAGTTAGaagatattaaatgtaaatattgtccgaaaatatttaaaagatattcaTCTCTTAAATGGCATGAAGATCGTCATTTCAATTCACCATTTAAATGTGATCATTGTCCAAAAACTTTtatgctaaaatatttattacgtgATCATTTAAGAACTCATACTGGTGAAAGACCGTTTAAATGTGAATATTGTCCAGCAGCCTTTGGCCATGTGGCAAATTTTAAACGACATATTTTAATACATGTTGgagaaaaaacttatttatgtaCTTTTGGTTGCGGTAAAGCATTTTATAAGGAACGTGAACGTACCGTACATGAGCGTACGCATACTGGTGAAAAACCATATGTTTGTGAATTATGCGGACGTTATTTTGCATATCAATGTAAGCTTAGCTTGCATAAGAAACGCTTTCATAtggataataaaaattggtCACATAAGTGTGATCAatgtaataaagtttttttaacgCCAGGAGAATTGCGTAATCATATTGTTGTTCATACTGGTGAAAAGCCATTTGCATGTGTTCAGTGTCCTGGTCGATTTAGTAAACCGAGTGGTTTGAGAGAACACAAGAAATTGCATTCGGGTGTTAAGAAACATGTGTGCAGCATTTGTAATAAAGCATTTGCTCAAACTGCTGGTTTATATGGTCACATGAAATCTCAtggaattattaaagaaaataccgaaataaattaa
Protein Sequence: MSTDIKVELLSEDLENDIPTFNQSDKCGEVFVTKRGIFSCFCIVCKQNFEEINHFTEHILLLHLDLSSAQNNLFNLIQNNNVEVDDISKTSIPHNLLEIKKDDVENINTDCLKILRKKIEITLDVFDPLNLEYEEDIKVETESSGREIFCEKEASTIAKVGDWNSRNSDDEETFDFNENEMDEKFPFKCDICNRSYKLKNAFVAHKKLHENVIPSCSHCGKNFGDKQSFKRHNQELCAQRKELGVKNTSKELEDIKCKYCPKIFKRYSSLKWHEDRHFNSPFKCDHCPKTFMLKYLLRDHLRTHTGERPFKCEYCPAAFGHVANFKRHILIHVGEKTYLCTFGCGKAFYKERERTVHERTHTGEKPYVCELCGRYFAYQCKLSLHKKRFHMDNKNWSHKCDQCNKVFLTPGELRNHIVVHTGEKPFACVQCPGRFSKPSGLREHKKLHSGVKKHVCSICNKAFAQTAGLYGHMKSHGIIKENTEIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -